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514 条记录 (耗时 0.014 秒)

    Aurone derivatives
    81.
    发明授权
    Aurone derivatives 失效
    Aurone衍生物

    公开(公告)号：US4259340A

    公开(公告)日：1981-03-31

    申请号：US71515

    申请日：1979-08-31

    申请人： Stephen R. Baker ,  William B. Jamieson ,  William J. Ross

    发明人： Stephen R. Baker ,  William B. Jamieson ,  William J. Ross

    IPC分类号： C07C45/63 ,  C07C65/40 ,  C07D257/04 ,  C07D307/83 ,  C07D307/92 ,  C07D317/30 ,  C07D405/02 ,  C07D405/10

    CPC分类号： C07D257/04 ,  C07C45/63 ,  C07C65/40 ,  C07D307/83 ,  C07D307/92 ,  C07D317/30 ,  Y10S514/826

    摘要： Substituted aurones of formula (I): ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are the same or different and can each represent hydrogen, halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.3-8 cycloalkyl, optionally substituted phenyl, C.sub.1-6 haloalkyl, amido, amino, cyano, hydroxy, nitro, C.sub.2-4 alkenyl, carboxyl, tetrazol-5-yl and --CH.dbd.CHCOOH; orwherein R.sup.1 and R.sup.2 taken together can represent a group of formula --CH.dbd.CH--CH.dbd.CH-- provided that at least one of R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is carboxyl, tetrazol-5-yl or --CH.dbd.CHCOOH;or a pharmaceutically-acceptable salt or ester thereof, are effective in the prophylactic chemotherapy of allergic conditions such as bronchial asthma.

    摘要翻译： 取代的式（I）的噢：其中R 1，R 2，R 3，R 4，R 5和R 6相同或不同，各自表示氢，卤素，C 1-6烷基，C 1-6烷氧基，C 3 -8环烷基，任选取代的苯基，C 1-6卤代烷基，酰氨基，氨基，氰基，羟基，硝基，C 2-4烯基，羧基，四唑-5-基和-CH = CHCOOH; 或者其中R 1和R 2一起可以表示式-CH = CH-CH = CH-的基团，条件是R 1，R 2，R 3，R 4，R 5和R 6中的至少一个是羧基，四唑-5-基或-CH = CHCOOH; 或其药学上可接受的盐或酯在过敏性疾病例如支气管哮喘的预防性化学疗法中是有效的。

    Stilbene optical brighteners
    86.
    发明授权
    Stilbene optical brighteners 失效
    STILBENE光学亮片

    公开(公告)号：US3781279A

    公开(公告)日：1973-12-25

    申请号：US3781279D

    申请日：1971-02-23

    申请人： STERLING DRUG INC

    发明人： CROUNSE N ,  DESAI K

    IPC分类号： C07C45/71 ,  C07D209/08 ,  C07D307/79 ,  C07D307/92 ,  C07D333/54 ,  C07D333/56 ,  C09B23/00

    CPC分类号： C07D307/92 ,  C07C45/71 ,  C07D209/08 ,  C07D307/79 ,  C07D333/54 ,  C07D333/56 ,  Y10S514/843 ,  C07C49/84

    摘要： BENZOFURANS, BENZOTHIOPHENES, INDOLES, NAPHTHOFURANS AND BENZOFURANOBENZOFURANS WHICH ARE SUBSTITUTED BY 4VINYLPHENYL GROUPS WHEREIN THE 2-POSITION OF THE VINYL IS SUBSTITUTED BY A MONOVALENT AROMATIC RADICAL HAVING ONE TO THREE AROMATIC RINGS ARE OPTICAL BRIGHTENING AGENTS USEFUL FOR WHITENING AND BRIGHTENING NATURAL AND SYNTHETIC FIBERS, PAPERS, RESINS AND THE LIKE. THE COMPOUNDS ARE CONVENIENTLY PREPARED BY INTERACTING BENZOFURANS, BENZOTHIOPHENES, INDOLES, NAPHTHOFURANS OF BENZOFURANOBENZOFURANS WHICH ARE SUBSTITUTED BY A P-TOLYL GROUP, WITH AN AROMATIC ALDEHYDE OR PREFERABLY THE ANIL DERIVATIVE THEREOF.

    摘要翻译： 2-苯基萘并[1,2-b]呋喃，2-苯基萘并[2,1-b]呋喃及其在苯环中被烷基，卤素或氰基取代的衍生物可用作抗生素剂，并且通过 具有强酸的萘氧基苯乙酮。

    Certain benzofuran derivatives useful for relief of pain,inflammation,pyresis and tussive irritation
    89.
    发明授权
    Certain benzofuran derivatives useful for relief of pain,inflammation,pyresis and tussive irritation 失效
    某些苯唑嘌呤衍生物有助于缓解疼痛，炎症，呕吐和刺激性刺激

    公开(公告)号：US3665074A

    公开(公告)日：1972-05-23

    申请号：US3665074D

    申请日：1969-05-20

    申请人： HAESSLE AB

    发明人： BRANDSTROM ARNE ELOF ,  CARLSSON STIG AKE INGEMAR

    IPC分类号： C07D307/83 ,  C07D307/92 ,  A61K27/00

    CPC分类号： C07D307/92 ,  C07D307/83

    摘要： The specification discloses benzofuran derivatives characterized by the formula: WHEREIN R represents a lower alkyl group, a phenyl group or a lower alkyl, lower alkoxy, dioxy-lower-alkylene, fluorine, chlorine, bromine or trifluoromethyl substituted phenyl group or a lower alkoxy substituted styryl group, R1 represents a hydrogen, fluorine, chlorine or bromine atom or a lower alkyl or lower alkoxy group, or together with R2 represents a benzo group, R2 represents a hydrogen, fluorine, chlorine or bromine atom or a lower alkyl or lower alkoxy group or provided R1 is a hydrogen atom, a nitro, amino, hydroxy, lower acyloxy, lower alkoxybenzoyloxy, lower dialkylamino or lower acylamino group, A represents an alkylene group containing not more than four carbon atoms, R3 represents a hydrogen atom or a lower alkyl group, R4 represents a lower alkyl, Beta -phenylethyl or benzyl group or NR3R4 represents a pyrrolidino, piperidino, hexamethyleneimino, morpholino, lower dialkylmorpholino, piperazino, lower alkyl piperazino, benzylpiperazino or tetrahydropyridino group, in the form of the free base or of a pharmaceutically acceptable salt thereof.