公开(公告)号：US09594078B2

公开(公告)日：2017-03-14

申请号：US12241583

申请日：2008-09-30

申请人： Young Ho Choi ,  Jaean Jung

发明人： Young Ho Choi ,  Jaean Jung

IPC分类号： G01N33/558 ,  G01N33/551 ,  G01N33/533 ,  G01N33/543 ,  G01N21/84

CPC分类号： G01N33/533 ,  G01N21/8483 ,  G01N33/54306 ,  G01N33/54366 ,  G01N33/558 ,  G01N2458/40 ,  Y10T436/143333

摘要： The present application discloses an analyte detection apparatus having at least one reservoir area and a wicking membrane, wherein a labeled specific binding partner is impregnated on the reservoir area; and a region on the wicking membrane where at least one chemical component is immobilized.

摘要翻译： 本申请公开了一种具有至少一个储存区域和芯吸膜的分析物检测装置，其中标记的特异性结合配偶体浸渍在储存区域上; 以及固定有至少一种化学成分的芯吸膜上的区域。

公开(公告)号：US09575056B2

公开(公告)日：2017-02-21

申请号：US13554417

申请日：2012-07-20

申请人： Hyeon Suk Kim ,  Tae-Hee Koo ,  Young Ho Choi

发明人： Hyeon Suk Kim ,  Tae-Hee Koo ,  Young Ho Choi

IPC分类号： G01N33/52

CPC分类号： G01N33/526 ,  C12Q1/32 ,  C12Y101/01027 ,  C12Y101/01049 ,  G01N33/523 ,  G01N33/98 ,  G01N2333/90209 ,  G01N2333/904

摘要： The present invention relates to a strip for an improved lateral flow assay of a biological sample on a single plane and a lateral flow chromatography assay using a test device containing the same. The strip of the present invention consists of a single-pad, which can improve lateral flow assay by providing an easy and simple procedure and clear visual reading. The strip of the present invention is consisted of sample application (sample) zone and reactant-resultant zone where the reaction mixture is deposited (reactant) are all on a same plane. In addition, the present invention provides a chromatographic method wherein hemoglobin is separated from analyte by a differential chromatography on the solid phase. Any interference of detection of the result by hemoglobin is removed by the present invention. The present invention provides advantages including an easy and simple procedure with a quick and clear response.

摘要翻译： 本发明涉及一种用于在单个平面上生物样品的改进的侧向流动测定的条带和使用含有该条带的测试装置的侧向流色谱分析。 本发明的条带由单垫组成，其可以通过提供简单且简单的程序和清晰的视觉读数来改善侧向流动测定。 本发明的条带由反应混合物沉积（反应物）的样品施加（样品）区域和反应物生成区域都在同一平面上。 此外，本发明提供了一种色谱法，其中通过固相上的差示色谱法将血红蛋白与分析物分离。 通过本发明除去血红蛋白检测结果的任何干扰。 本发明提供了包括具有快速和明确响应的简单且简单的程序的优点。

公开(公告)号：USD694424S1

公开(公告)日：2013-11-26

申请号：US29440920

申请日：2012-12-28

申请人： Access Bio, Inc.

设计人： Joon Hyeok Kwak ,  Tae-Hee Koo ,  Hyeonsuk Kim ,  Young Ho Choi

公开(公告)号：US20130022969A1

公开(公告)日：2013-01-24

申请号：US13554417

申请日：2012-07-20

申请人： Hyeon Suk KIM ,  Tae-Hee KOO ,  Young Ho CHOI

发明人： Hyeon Suk KIM ,  Tae-Hee KOO ,  Young Ho CHOI

IPC分类号： C12Q1/32 ,  C12Q1/68

CPC分类号： G01N33/526 ,  C12Q1/32 ,  C12Y101/01027 ,  C12Y101/01049 ,  G01N33/523 ,  G01N33/98 ,  G01N2333/90209 ,  G01N2333/904

摘要： The present invention relates to a strip for an improved lateral flow assay of a biological sample on a single plane and a lateral flow chromatography assay using a test device containing the same. The strip of the present invention consists of a single-pad, which can improve lateral flow assay by providing an easy and simple procedure and clear visual reading. The strip of the present invention is consisted of sample application (sample) zone and reactant-resultant zone where the reaction mixture is deposited (reactant) are all on a same plane. In addition, the present invention provides a chromatographic method wherein hemoglobin is separated from analyte by a differential chromatography on the solid phase. Any interference of detection of the result by hemoglobin is removed by the present invention. The present invention provides advantages including an easy and simple procedure with a quick and clear response.

摘要翻译： 本发明涉及一种用于在单个平面上生物样品的改进的侧向流动测定的条带和使用含有该条带的测试装置的侧向流色谱分析。 本发明的条带由单垫组成，其可以通过提供简单且简单的程序和清晰的视觉读数来改善侧向流动测定。 本发明的条带由反应混合物沉积（反应物）的样品施加（样品）区域和反应物生成区域都在同一平面上。 此外，本发明提供了一种色谱法，其中通过固相上的差示色谱法将血红蛋白与分析物分离。 通过本发明除去血红蛋白检测结果的任何干扰。 本发明提供了包括具有快速和明确响应的简单且简单的程序的优点。

公开(公告)号：US20050227275A1

公开(公告)日：2005-10-13

申请号：US11102001

申请日：2005-04-07

申请人： Jaean Jung ,  Young Choi ,  Youngsun Kim

发明人： Jaean Jung ,  Young Choi ,  Youngsun Kim

IPC分类号： C12Q1/68

CPC分类号： C12Q1/701 ,  C12Q1/6816 ,  C12Q1/6834 ,  Y02A50/53 ,  C12Q2565/625 ,  C12Q2563/131 ,  C12Q2537/125 ,  C12Q2565/137 ,  C12Q2545/101

摘要： The present application discloses a system for detecting target nucleic acid comprising: a container comprising a nucleic acid amplification mix comprising a primer labeled with different haptens at its 5′ and 3′ ends, and optionally dNTP labeled with a hapten to form a nucleic acid complex; and a lateral flow test device comprising a reservoir area comprising reagent conditions suitable for binding of a specific binding partner with the nucleic acid complex; a dye area comprising a specific binding partner to the nucleic acid complex, wherein the specific binding partner is linked or conjugated to a reporter dye or another hapten; and a test area comprising a different specific binding partner specific to a different aspect of the nucleic acid complex.

摘要翻译： 本申请公开了一种用于检测靶核酸的系统，包括：容器，其包含核酸扩增混合物，其包含在其5'和3'末端用不同半抗原标记的引物，以及任选地用半抗原标记的dNTP以形成核酸复合物 ; 和侧流测试装置，其包括储存区域，其包含适合于将特异性结合配偶体与核酸复合物结合的试剂条件; 染料区域，其包含与所述核酸复合物的特异性结合配偶体，其中所述特异性结合配偶体与报告染料或其他半抗原连接或缀合; 以及包含对核酸复合物的不同方面特异的不同特异性结合伴侣的测试区域。

公开(公告)号：US20160244803A1

公开(公告)日：2016-08-25

申请号：US15096994

申请日：2016-04-12

申请人： ACCESS BIO, INC.

发明人： Jaean JUNG ,  Jae-Kyoung CHOI ,  Won-Jung KIM ,  Tae-Hee KOO ,  Min-A PARK

IPC分类号： C12Q1/32

CPC分类号： C12Q1/32 ,  A61B5/14542 ,  A61B5/14551 ,  A61B5/1468 ,  A61B5/1486 ,  A61B2562/0295 ,  A61B2562/063 ,  G01N27/3274 ,  G01N2333/904

摘要： Provided is a diagnostic apparatus. The diagnostic apparatus includes a microfluidic chip including first and second measurement parts for respectively measuring an amount of hemoglobin and an active degree of an enzyme within a blood sample. The second measurement part of the microfluidic chip analyzes the active degree of the enzyme within the blood sample using voltammetry.

公开(公告)号：US09340818B2

公开(公告)日：2016-05-17

申请号：US13878337

申请日：2011-10-05

申请人： Jaean Jung ,  Jae-Kyoung Choi ,  Won-Jung Kim ,  Tae-Hee Koo ,  Min-A Park

发明人： Jaean Jung ,  Jae-Kyoung Choi ,  Won-Jung Kim ,  Tae-Hee Koo ,  Min-A Park

IPC分类号： G01N33/00 ,  C12Q1/32 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1468 ,  A61B5/1486 ,  G01N27/327

CPC分类号： C12Q1/32 ,  A61B5/14542 ,  A61B5/14551 ,  A61B5/1468 ,  A61B5/1486 ,  A61B2562/0295 ,  A61B2562/063 ,  G01N27/3274 ,  G01N2333/904

摘要： Provided is a diagnostic apparatus. The diagnostic apparatus includes a microfluidic chip including first and second measurement parts for respectively measuring an amount of hemoglobin and an active degree of an enzyme within a blood sample. The second measurement part of the microfluidic chip analyzes the active degree of the enzyme within the blood sample using voltammetry.

公开(公告)号：US12044679B2

公开(公告)日：2024-07-23

申请号：US18455397

申请日：2023-08-24

申请人： Access Bio, Inc.

发明人： Young Ho Choi ,  Jungho Back ,  Hyoungsoo Kim ,  Hanmaru Chon ,  Myungkyu Jang ,  Hyeon Suk Kim ,  Myoun Woo Kim ,  Hyewon Park ,  Suji Lee ,  Olivia Haejeong Kim

IPC分类号： G01N33/543 ,  B01J19/00 ,  B01L3/00 ,  G01N33/569

CPC分类号： G01N33/54391 ,  B01J19/0093 ,  B01L3/5029 ,  B01L3/56 ,  G01N33/54387 ,  G01N33/54389 ,  G01N33/56983 ,  B01L2200/0668 ,  B01L2300/0609 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0809 ,  B01L2300/0825 ,  G01N2333/08 ,  G01N2333/165 ,  G01N2469/10

摘要： Diagnostic assay devices for detecting the presence of an analyte in a sample solution may comprise a microreactor configured to form a sample solution containing the analyte, flow the sample solution therethrough in a first direction to form an analyte-capture molecule complex, and transfer the sample solution to an absorbent strip pad configured to flow therethrough, in a second direction crossing the first direction, the sample solution including the analyte-capture molecule complex and indicate a presence of the analyte-capture molecule complex. The diagnostic devices may be used, for example, to identify the presence of SARS-Cov2, RSV, influenza A, influenza B or other pathogens in samples from patients.

公开(公告)号：US20240069024A1

公开(公告)日：2024-02-29

申请号：US18455397

申请日：2023-08-24

申请人： Access Bio, Inc.

发明人： Young Ho Choi ,  Jungho Back ,  Hyoungsoo Kim ,  Hanmaru Chon ,  Myungkyu Jang ,  Hyeon Suk Kim ,  Myoun Woo Kim ,  Hyewon Park ,  Suji Lee ,  Olivia Haejeong Kim

IPC分类号： G01N33/569 ,  G01N33/543

CPC分类号： G01N33/56983 ,  G01N33/54387 ,  B01L2200/0668 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0825 ,  G01N2333/165 ,  G01N2469/10

摘要： Diagnostic assay devices for detecting the presence of an analyte in a sample solution may comprise a microreactor configured to form a sample solution containing the analyte, flow the sample solution therethrough in a first direction to form an analyte-capture molecule complex, and transfer the sample solution to an absorbent strip pad configured to flow therethrough, in a second direction crossing the first direction, the sample solution including the analyte-capture molecule complex and indicate a presence of the analyte-capture molecule complex. The diagnostic devices may be used, for example, to identify the presence of SARS-Cov2, RSV, influenza A, influenza B or other pathogens in samples from patients.

公开(公告)号：US20240069016A1

公开(公告)日：2024-02-29

申请号：US18455410

申请日：2023-08-24

申请人： Access Bio, Inc.

发明人： Young Ho Choi ,  Jungho Back ,  Hyoungsoo Kim ,  Hanmaru Chon ,  Myungkyu Jang ,  Hyeon Suk Kim ,  Myoun Woo Kim ,  Hyewon Park ,  Suji Lee ,  Olivia Haejeong Kim

IPC分类号： G01N33/543 ,  B01J19/00 ,  B01L3/00

CPC分类号： G01N33/54389 ,  B01J19/0093 ,  B01L3/5029 ,  B01L3/56 ,  B01L2300/0609 ,  B01L2300/0809 ,  G01N2333/08

摘要： Diagnostic assay devices for detecting the presence of an analyte in a sample solution may comprise a microreactor configured to form a sample solution containing the analyte, flow the sample solution therethrough in a first direction to form an analyte-capture molecule complex, and transfer the sample solution to an absorbent strip pad configured to flow therethrough, in a second direction crossing the first direction, the sample solution including the analyte-capture molecule complex and indicate a presence of the analyte-capture molecule complex. The diagnostic devices may be used, for example, to identify the presence of SARS-Cov2, RSV, influenza A, influenza B or other pathogens in samples from patients.