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    NEONATAL AND PEDIATRIC BLOOD FILTRATION SYSTEM
    1.
    发明申请
    NEONATAL AND PEDIATRIC BLOOD FILTRATION SYSTEM 有权

    公开(公告)号：US20220001088A1

    公开(公告)日：2022-01-06

    申请号：US17309536

    申请日：2020-03-26

    申请人： CHF Solutions, Inc.

    发明人： David Lerner ,  David Haskvitz ,  Franz Willems Ulrich

    IPC分类号： A61M1/34

    摘要： A blood filtration system may to couple to an infusion pump that is external to the blood filtration system. The blood filtration system may include a blood circuit, for instance a variable-volume blood circuit. An infusion port may be in communication with the blood circuit and may receive an infusion fluid pumped by the infusion pump. A filtration pump may extract a filtrate fluid from a filter. The filtrate fluid may include filtered plasma constituents. A fluid characteristic sensor may measure one or more of pressure or flow rate of the infusion fluid pumped by the infusion pump. A controller may monitor the fluid characteristic sensor to determine a change in the pressure or flow rate of the infusion fluid. The controller may modulate a speed of the variable-speed filtration pump based on the change in the pressure or flow rate of the infusion fluid.

    Controller for ultrafiltration blood circuit which prevent hypotension by monitoring osmotic pressure in blood
    2.
    发明授权
    Controller for ultrafiltration blood circuit which prevent hypotension by monitoring osmotic pressure in blood 有权
    超滤血液回路控制器，通过监测血液中的渗透压来预防低血压

    公开(公告)号：US08070707B2

    公开(公告)日：2011-12-06

    申请号：US12172303

    申请日：2008-07-14

    申请人： Mark Gelfand ,  John J. O'Mahony ,  Howard R. Levin

    发明人： Mark Gelfand ,  John J. O'Mahony ,  Howard R. Levin

    IPC分类号： A61M37/00 ,  C02F1/44 ,  C02F1/00

    CPC分类号： A61M1/34 ,  A61M1/1611 ,  A61M1/3403 ,  A61M1/341 ,  A61M1/3609 ,  A61M1/3639 ,  A61M1/367 ,  A61M2205/3306 ,  A61M2205/3331 ,  A61M2205/3344 ,  A61M2205/3375 ,  A61M2205/50 ,  A61M2230/20

    摘要： A device for continuously measuring osmotic pressure of blood flowing through an extracorporeal blood circuit including: a blood passage further comprising a withdrawal blood passage connectable to a blood vessel in a patient and an infusion blood passage connectable to a blood vessel in a patient; a filter further comprising a filtrate chamber, a blood chamber and a permeable membrane separating the filtrate chamber and blood chamber, wherein the blood chamber is in fluid communication with the blood passage; a pressure sensor measuring a pressure difference between the filtrate chambers and the blood chamber, and a controller receiving a pressure signal from the pressure sensor, determining an osmotic pressure across the permeable membrane of the filter, and adjusting a rate of removal of fluid from blood in the filter if the determined osmotic pressure level varies from a predetermined osmotic pressure setting.

    摘要翻译： 一种用于连续测量流过体外血液循环的血液的渗透压的装置，包括：血液通道，其还包括可连接到患者血管的抽血血道和可连接到患者血管的输注血液通道; 过滤器还包括滤液室，血液室和分离滤液室和血液室的可渗透膜，其中血液室与血液通道流体连通; 测量滤液室和血液室之间的压力差的压力传感器，以及接收来自压力传感器的压力信号的控制器，确定过滤器的渗透膜上的渗透压，以及调节从血液中去除流体的速率 如果确定的渗透压水平从预定的渗透压设定变化，则在过滤器中。

    Method and apparatus for blood withdrawal and infusion using a pressure controller
    3.
    发明授权
    Method and apparatus for blood withdrawal and infusion using a pressure controller 有权
    使用压力控制器进行抽血和输液的方法和装置

    公开(公告)号：US07955289B2

    公开(公告)日：2011-06-07

    申请号：US12330171

    申请日：2008-12-08

    申请人： John O'Mahony ,  Mark Gelfand ,  Edward G. Rychlick

    发明人： John O'Mahony ,  Mark Gelfand ,  Edward G. Rychlick

    IPC分类号： A61M37/00

    CPC分类号： A61M1/34 ,  A61M1/1692 ,  A61M1/341 ,  A61M1/3639 ,  A61M1/3656 ,  A61M2205/15 ,  A61M2205/18 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/50 ,  A61M2205/502 ,  B01D61/22

    摘要： A method and apparatus for controlling blood withdrawal and infusion flow rate with the use of a pressure controller. The pressure controller uses pressure targets based upon occlusion limits that are calculated as a function of flow. The controller has the ability to switch from controlling withdrawal pressure to controlling infusion pressure based upon the detection of an occlusion. The controller distinguishes between partial and total occlusions of the withdrawal vein providing blood access. Depending on the nature of occlusion, the controller limits or temporarily reverses blood flow and, thus, prevents withdrawal vessel collapse or reverses blood flow to quickly infuse blood into the vessel without participation from operator.

    摘要翻译： 一种使用压力控制器控制取血和输注流速的方法和装置。 压力控制器使用基于作为流量的函数计算的阻塞极限的压力目标。 控制器能够根据遮挡的检测从控制提取压力转换到控制输液压力。 控制器区分提供血液通道的撤离静脉的部分和全部闭塞。 根据闭塞的性质，控制器限制或暂时逆转血液流动，从而防止撤离血管塌陷或逆转血液，以便在没有操作者参与的情况下将血液快速注入血管。

    Cuvette apparatus and system for measuring optical properties of a liquid such as blood
    5.
    发明授权
    Cuvette apparatus and system for measuring optical properties of a liquid such as blood 有权
    比色杯装置和用于测量诸如血液的液体的光学性质的系统

    公开(公告)号：US07671974B2

    公开(公告)日：2010-03-02

    申请号：US10975411

    申请日：2004-10-29

    申请人： John J. O'Mahony ,  Xinrui Hou ,  Edwin B. Merrick

    发明人： John J. O'Mahony ,  Xinrui Hou ,  Edwin B. Merrick

    IPC分类号： G01N33/48 ,  G01N21/05

    CPC分类号： A61B5/14557 ,  G01N21/05 ,  G01N21/359

    摘要： A optical sensor for measuring tranmissive properties of a solution having: a cuvette body with an enclosed flow passage for the solution, wherein the flow passage further includes a solution inlet and a solution outlet and a cuvette between the inlet and outlet; a light source projecting light of a predetermined wavelength through the cuvette and solution flowing through the cuvette and to a light sensor, wherein the cuvette has inner wall surfaces opaque to the light of said predetermined wavelength, and the inner wall is in contact with the solution.

    摘要翻译： 一种用于测量溶液的透射性质的光学传感器，其具有：具有用于溶液的封闭流动通道的比色皿体，其中所述流动通道还包括溶液入口和溶液出口以及在入口和出口之间的比色杯; 光源，其通过比色杯预定波长的光和流过比色杯的光和光传感器，其中所述反应杯具有对于所述预定波长的光不透明的内壁表面，并且所述内壁与所述溶液接触 。

    Self-loading peristaltic pump for extracorporeal blood circuit
    6.
    发明授权
    Self-loading peristaltic pump for extracorporeal blood circuit 有权
    用于体外血液循环的自加载蠕动泵

    公开(公告)号：US07547200B2

    公开(公告)日：2009-06-16

    申请号：US11362197

    申请日：2006-02-27

    申请人： John J. O'Mahony ,  Sonny Behan

    发明人： John J. O'Mahony ,  Sonny Behan

    IPC分类号： F04B43/12

    CPC分类号： F04B43/1253

    摘要： A peristaltic pump is disclosed having pump motor with a rotating motor shaft and a shaft axis; a peristaltic pump head rotatably mounted on the motor shaft; a raceway having a semi-circular track arranged around the pump head and coaxial with the shaft axis, wherein the track has a beveled edge at an entrance to the raceway to receive a tube loop being loaded into the pump; the pump head includes at least one roller orbiting the raceway and compressing the tube loop against said raceway, and a cartridge to which the tube loop is attached and mountable on the raceway.

    摘要翻译： 公开了一种具有旋转电机轴和轴线的泵马达的蠕动泵; 可旋转地安装在电动机轴上的蠕动泵头; 滚道，其具有围绕泵头并与轴轴线同轴的半圆形轨道，其中所述轨道在所述滚道的入口处具有倾斜边缘，以接收加载到所述泵中的管道环路; 所述泵头包括至少一个绕所述滚道运动的滚筒，并且将所述管回路压靠所述滚道，以及将所述管环连接并安装在所述滚道上的筒。

    Blood Volume Controller During Fluid Removal
    7.
    发明申请
    Blood Volume Controller During Fluid Removal 有权
    流体清除过程中的血量控制器

    公开(公告)号：US20070055198A1

    公开(公告)日：2007-03-08

    申请号：US11460322

    申请日：2006-07-27

    申请人： John O'Mahony ,  Paul Sobotka ,  Edward Rychlick

    发明人： John O'Mahony ,  Paul Sobotka ,  Edward Rychlick

    IPC分类号： A61M31/00

    CPC分类号： A61M5/14212 ,  A61M5/1723 ,  A61M2230/207

    摘要： A blood volume control method has been developed including: monitoring a condition of a patient (such as hematocrit (Hct)), wherein the condition is indicative of blood volume in the patient; automatically determining that the condition indicates a low blood volume in the patient; automatically infusing an infusion solution into the patient in response to the determination of a low blood volume, and automatically adjusting the infusion to maintain the monitored condition at a predetermined value.

    摘要翻译： 已经开发了血容量控制方法，包括：监测患者的状况（例如血细胞比容（Hct）），其中所述状况指示患者的血容量; 自动确定病人体内血液含量低; 响应于低血容量的确定，自动将输注溶液输入患者体内，并自动调节输液以将监测条件维持在预定值。

    Self-loading peristaltic pump for extracorporeal blood circuit
    10.
    发明申请
    Self-loading peristaltic pump for extracorporeal blood circuit 有权

    公开(公告)号：US20060140799A1

    公开(公告)日：2006-06-29

    申请号：US11362197

    申请日：2006-02-27

    申请人： John O'Mahony ,  Sonny Behan

    发明人： John O'Mahony ,  Sonny Behan

    IPC分类号： F04B43/12

    CPC分类号： F04B43/1253

    摘要： A peristaltic pump is disclosed having pump motor with a rotating motor shaft and a shaft axis; a peristaltic pump head rotatably mounted on the motor shaft; a raceway having a semi-circular track arranged around the pump head and coaxial with the shaft axis, wherein the track has a beveled edge at an entrance to the raceway to receive a tube loop being loaded into the pump; the pump head includes at least one roller orbiting the raceway and compressing the tube loop against said raceway, and a cartridge to which the tube loop is attached and mountable on the raceway.