公开(公告)号：US5312972A

公开(公告)日：1994-05-17

申请号：US969705

申请日：1992-10-29

申请人： Barry A. Cullen

发明人： Barry A. Cullen

IPC分类号： C07C227/18 ,  C07C229/16 ,  C07F9/38 ,  C07C229/00

CPC分类号： C07C227/18 ,  C07F9/3808

摘要： A process for preparing N-phosphonomethyl iminodiacetic acid wherein solutions of an alkali metal salt of IDA are reacted with formaldehyde so as to form the alkali metal salt of hydroxymethyliminodiacetic acid (HMIDA). The HMIDA can be subsequently reacted with a phosphorous source such as phosphorous acid to produce PMIDA in good yield.

摘要翻译： 一种制备N-膦酰甲基亚氨基二乙酸的方法，其中IDA的碱金属盐溶液与甲醛反应形成羟甲基亚氨基二乙酸（HMIDA）的碱金属盐。 HMIDA随后可以与磷源如亚磷酸反应以产生良好的产率的PMIDA。

公开(公告)号：US5284972A

公开(公告)日：1994-02-08

申请号：US76446

申请日：1993-06-14

申请人： Brian A. Parker ,  Barry A. Cullen

发明人： Brian A. Parker ,  Barry A. Cullen

IPC分类号： C07C231/02 ,  C07C233/47 ,  C07C233/49 ,  C07C233/83 ,  C07C229/00

CPC分类号： C07C233/47 ,  C07C233/49

摘要： Novel N-acyl derivatives of ethylenediaminetriacetic acid are disclosed, as well as a process for preparing the same.

摘要翻译： 公开了乙二胺三乙酸的新型N-酰基衍生物及其制备方法。

公开(公告)号：US5266323A

公开(公告)日：1993-11-30

申请号：US705276

申请日：1991-05-24

申请人： James L. Guthrie ,  Narendar P. Luthra ,  Clifton L. Kehr ,  Darwin S. Bull

发明人： James L. Guthrie ,  Narendar P. Luthra ,  Clifton L. Kehr ,  Darwin S. Bull

IPC分类号： A23K1/18 ,  A01K97/04 ,  A23K1/20 ,  A61L31/06 ,  C08G18/32 ,  C08G18/42 ,  C08G18/48 ,  C08G63/06 ,  C08L75/00 ,  C08L75/06 ,  C09J175/00 ,  C09J175/06 ,  A01N25/08

CPC分类号： C08G18/4887 ,  A01K97/045 ,  A61L31/06 ,  C08G18/3221 ,  C08G18/4283 ,  C08G18/4286 ,  C08G2101/0083 ,  C08G2220/00 ,  C08G2230/00

摘要： A degradable article comprising a polyurethane polymer gel or foam whose polymer structure contains hydrolytically unstable ester linkages and various additives. The article can be constructed so that some of the additives are released from the article at a sustained rate. In a preferred embodiment the additives are sensory stimulants for marine or aquatic organisms and the article is used as bait for those organisms.

公开(公告)号：US5250728A

公开(公告)日：1993-10-05

申请号：US806567

申请日：1991-12-12

申请人： Brian A. Parker ,  Barry A. Cullen ,  Roger R. Gaudette

发明人： Brian A. Parker ,  Barry A. Cullen ,  Roger R. Gaudette

IPC分类号： C07C227/22 ,  C07C227/26 ,  C07C229/16 ,  C07C229/26 ,  C07D241/08 ,  C11D1/10 ,  C11D3/33 ,  C07C229/00

CPC分类号： C07D241/08 ,  C07C227/26 ,  C07C229/16 ,  C11D1/10 ,  C11D3/33

摘要： Synthesis of ethylenediaminetriacetic acid (ED3A) or its salts is disclosed. A salt of N,N'-ethylenediaminediacetic acid (ED2AH.sub.2) is condensed with formaldehyde to form a stable 5-membered ring intermediate. The addition of cyanide across this cyclic material forms ethylenediamine N,N'-diacetic acid-N'-cyanomethyl or salts thereof (mononitrile-diacid). The nitrile in aqueous solutions may be spontaneously cyclized to form 2-oxo-1,4-piperazinediacetic acid (3KP) or salts thereof, which is the desired cyclic intermediate. In the presence of excess base, salts of ED3A are formed in excellent yield and purity. Alternatively, the starting material is ED2AH.sub.a X.sub.b, where x is a base cation, e.g., an alkali or alkaline earth metal, a is 1 to 2, and b is 0 to 1 in aqueous solutions. The reaction mixture also can be acidified to ensure complete formation of carboxymethyl-2-oxopiperazine (the lactam) prior to the reaction. Formaldehyde is added, essentially resulting in the hydroxymethyl derivative. On the addition of a cyanide source, 1-cyanomethyl-4-carboxymethyl-2-ketopiperazine (mononitrile diacid) or a salt thereof is formed. Upon the addition of any suitable base or acid, this material may be hydrolyzed to 3KP. The addition of a base will open this ring structure to form the salt of ED3A.

公开(公告)号：US5235089A

公开(公告)日：1993-08-10

申请号：US843867

申请日：1992-02-27

申请人： Richard P. Woodbury ,  Jon C. Thunberg ,  Steven P. VanKouwenberg ,  Walter B. Begonis

发明人： Richard P. Woodbury ,  Jon C. Thunberg ,  Steven P. VanKouwenberg ,  Walter B. Begonis

IPC分类号： B01J31/02 ,  C07B61/00 ,  C07C253/10 ,  C07C253/34 ,  C07C255/46

CPC分类号： C07C253/10 ,  C07C2101/14

摘要： A process for the preparation of isophorone nitrile utilizing solutions of lithium hydroxide or lithium cyanide, solid LiOH or solid LiOH.cndot.H.sub.2 O as a catalyst. The reaction is carried out under precisely controlled temperature conditions and cyanide feed rate profiles to maintain a reasonably constant concentration of non-reacted cyanide, thereby minimizing the formation of undesirable diisophorone, its nitrile derivative(s) and HCN polymers. A polyacidic acid can be used to acidify the batch, followed by filtration to remove the precipitated lithium salt of the acid, and vacuum distillation to remove liberated HCN and excess isophorone. The resulting isophorone nitrile is obtained in high yield and with low impurity content.

公开(公告)号：US5985798A

公开(公告)日：1999-11-16

申请号：US90833

申请日：1998-06-04

申请人： Joseph J. Crudden

发明人： Joseph J. Crudden

IPC分类号： A01N37/30 ,  A01N57/20 ,  A01N57/00

CPC分类号： A01N57/20

摘要： An adjuvant for glyphosate having increased activity, lower irritancy and lower toxicity than conventional adjuvants, and method of controlling weeds using the same. The adjuvant is C.sub.8 to C.sub.22 sarcosinate or sarcosinate salt, such as sodium cocoyl sarcosinate, sodium lauroyl sarcosinate, or combinations thereof, which is combined with glyphosate in low concentrations and provides effective activity.

摘要翻译： 与常规佐剂相比，具有增加的活性，较低的刺激性和较低的毒性的草甘膦的佐剂，以及使用其的控制杂草的方法。 佐剂是C8-C22肌氨酸盐或肌氨酸盐，例如椰子酰基肌氨酸钠，月桂酰肌氨酸钠或其组合，其与低浓度的草甘膦组合并提供有效活性。

公开(公告)号：US5973192A

公开(公告)日：1999-10-26

申请号：US978759

申请日：1997-11-26

申请人： Richard P. Woodbury ,  John B. Stallman ,  George F. Winterson ,  Kenneth L. Avery

发明人： Richard P. Woodbury ,  John B. Stallman ,  George F. Winterson ,  Kenneth L. Avery

IPC分类号： G02C7/02 ,  C07C323/52 ,  C08G75/04 ,  G02B1/04 ,  C07C321/00

CPC分类号： C07C323/52

摘要： Novel thioglycerol derivatives, processes for their manufacture, and optical materials made from such compounds. The thioglycerol derivatives have high concentrations of sulfur relative to compounds conventionally used for optical materials, and thus exhibit high refractive indices without sacrificing processability.

公开(公告)号：US5688981A

公开(公告)日：1997-11-18

申请号：US749364

申请日：1996-11-21

申请人： Arthur M. Nonomura

发明人： Arthur M. Nonomura

IPC分类号： A61K31/16 ,  A01N59/16 ,  C07C229/16 ,  C07C233/36 ,  C07C233/47 ,  C07C233/49 ,  C07F1/10 ,  C11D1/10 ,  C11D3/33

CPC分类号： C11D3/48 ,  A01N59/16 ,  C07C233/36 ,  C11D1/10 ,  C11D3/33

摘要： Silver chelating agent and surfactant that exhibits photosensitivity and antimicrobial activity. The silver can be chelated with ethylenediaminetriacetic acid (ED3A) or salts thereof, or preferably with N-acyl ED3A or salts thereof. Antimicrobial activity is exhibited even at very low silver levels.

摘要翻译： 具有光敏性和抗菌活性的银螯合剂和表面活性剂。 银可以与乙二胺三乙酸（ED3A）或其盐，或优选与N-酰基ED3A或其盐螯合。 即使在非常低的银水平下也能显示出抗菌活性。

公开(公告)号：US5449822A

公开(公告)日：1995-09-12

申请号：US60219

申请日：1993-05-07

申请人： Brian A. Parker ,  Barry A. Cullen ,  Roger R. Gaudette

发明人： Brian A. Parker ,  Barry A. Cullen ,  Roger R. Gaudette

IPC分类号： C07C227/22 ,  C07C227/26 ,  C07C229/16 ,  C07C229/26 ,  C07D241/08 ,  C11D1/10 ,  C11D3/33 ,  C07C229/00

CPC分类号： C07D241/08 ,  C07C227/26 ,  C07C229/16 ,  C11D1/10 ,  C11D3/33

摘要： Synthesis of ethylenediaminetriacetic acid (ED3A) or its salts is disclosed. A salt of N,N'-ethylenediaminediacetic acid (ED2AH.sub.2) is condensed with formaldehyde to form a stable 5-membered ring intermediate. The addition of cyanide across this cyclic material forms ethylenediamine N,N'-diacetic acid-N'-cyanomethyl or salts thereof (mononitrile-diacid). The nitrile in aqueous solutions may be spontaneously cyclized to form 2-oxo-1,4-piperazinediacetic acid (3KP) or salts thereof, which is the desired cyclic intermediate. In the presence of excess base, salts of ED3A are formed in excellent yield and purity. Alternatively, the starting material is ED2AH.sub.a X.sub.b, where x is a base cation, e.g., an alkali or alkaline earth metal, a is 1 to 2, and b is 0 to 1 in aqueous solutions. The reaction mixture also can be acidified to ensure complete formation of carboxymethyl-2-oxopiperazine (the lactam) prior to the reaction. Formaldehyde is added, essentially resulting in the hydroxymethyl derivative. On the addition of a cyanide source, 1-cyanomethyl-4-carboxymethyl-2-ketopiperazine (mononitrile diacid) or a salt thereof is formed. Upon the addition of any suitable base or acid, this material may be hydrolyzed to 3KP. The addition of a base will open this ring structure to form the salt of ED3A.

摘要翻译： 公开了乙二胺三乙酸（ED3A）或其盐的合成。 N，N'-乙二胺二乙酸（ED2AH2）的盐与甲醛缩合形成稳定的5元环中间体。 在该环状物质中加入氰化物形成乙二胺N，N'-二乙酸-N'-氰基甲基或其盐（单腈 - 二酸）。 水溶液中的腈可以自发环化以形成2-氧代-1,4-哌嗪二乙酸（3KP）或其盐，其为期望的环状中间体。 在过量碱的存在下，ED3A的盐以优异的产率和纯度形成。 或者，原料为ED2AHaXb，其中x为碱性阳离子，例如碱金属或碱土金属，a为1至2，b为0至1。 反应混合物也可以酸化以确保在反应之前完全形成羧甲基-2-氧代哌嗪（内酰胺）。 加入甲醛，基本上得到羟甲基衍生物。 在加入氰化物源时，形成1-氰甲基-4-羧甲基-2-酮哌嗪（单腈二酸）或其盐。 加入任何合适的碱或酸后，该物质可水解成3KP。 添加碱将打开该环结构形成ED3A的盐。

公开(公告)号：US5446211A

公开(公告)日：1995-08-29

申请号：US221498

申请日：1994-04-01

申请人： Gerald J. O'Neill ,  Robert J. Bulka

发明人： Gerald J. O'Neill ,  Robert J. Bulka

IPC分类号： C07C41/22 ,  C07C43/12 ,  C07C41/00 ,  C07C43/00

CPC分类号： C07C41/22

摘要： The synthesis of fluorinated dimethyl ethers of the formula CF.sub.2 HOCCl.sub.x F.sub.y H.sub.3-(x+y) wherein x is 0, 1 or 2; y is 1, 2 or 3; and wherein (x+y) is 1, 2 or 3. The process involves chlorination of methyl difluoromethyl ether in the presence of a solvent to form a chlorinated reaction product of the formula CF.sub.2 HOCH.sub.3-z Cl.sub.z wherein z is 1, 2 or 3. The process may also be carried out in the presence of oxygen in order to inhibit the formation of CF.sub.2 HOCCl.sub.3. The resulting compound(s) is then fluorinated with HF before or after separation, to give a fluorinated reaction product including the aforementioned fluorinated dimethyl ethers.

摘要翻译： 式CF 2 HOCCl x F y H 3 - （x + y）的氟化二甲醚的合成，其中x为0,1或2; y为1,2或3; 并且其中（x + y）为1,2或3.该方法包括在溶剂存在下甲基二氟甲基醚的氯化，形成式CF 2 HOCH 3 -ZClz的氯化反应产物，其中z为1,2或3。 方法也可以在氧气存在下进行以抑制CF 2 HOCCl 3的形成。 然后将所得化合物在分离之前或之后用HF氟化，得到包含上述氟化二甲醚的含氟反应产物。