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19 条记录 (耗时 0.019 秒)

    Contact lenses based on biocompatible polyurethane and polyurea-urethane hydrated polymers
    1.
    发明授权
    Contact lenses based on biocompatible polyurethane and polyurea-urethane hydrated polymers 失效
    基于生物相容性聚氨酯和聚脲 - 氨基甲酸酯水合聚合物的隐形眼镜

    公开(公告)号：US4886866A

    公开(公告)日：1989-12-12

    申请号：US312331

    申请日：1989-02-16

    申请人： James A. Braatz ,  Clifton L. Kehr

    发明人： James A. Braatz ,  Clifton L. Kehr

    IPC分类号： C08G18/10 ,  C08G18/48 ,  G02B1/04

    CPC分类号： C08G18/4837 ,  C08G18/10 ,  C08G18/4833 ,  G02B1/043 ,  C08G2210/00 ,  Y10S528/904

    摘要： Hydrophilic polymeric soft contact lenses which are characterized by their biocompatibility and resistance to nonspecific protein adsorption. At least 75%, preferably at least 80%, of the prepolymers from which the lenses are prepared are isocyanate-capped oxyethylene-based diols or polyols having molecular weight of about 7000-30,000. Essentially all of the hydroxyl groups of the diols or polyols are capped with polyisocyanate prior to formation of the hydrated polymer of which the contact lenses are made.

    摘要翻译： 亲水性聚合物软性隐形眼镜，其特征在于它们的生物相容性和对非特异性蛋白质吸附的抗性。 制备透镜的预聚物的至少75％，优选至少80％是分子量约为7000-3000的异氰酸酯封端的氧化乙烯基二醇或多元醇。 在形成隐形眼镜的水合聚合物形成之前，二醇或多元醇的基本上所有羟基被多异氰酸酯封端。

    Novel hydrophobic polyurethane foams
    3.
    发明授权
    Novel hydrophobic polyurethane foams 失效
    新型疏水性聚氨酯泡沫

    公开(公告)号：US3959191A

    公开(公告)日：1976-05-25

    申请号：US537617

    申请日：1974-12-30

    申请人： Clifton L. Kehr ,  Nelson S. Marans

    发明人： Clifton L. Kehr ,  Nelson S. Marans

    IPC分类号： C08J9/02 ,  C08G18/10 ,  C08G18/14

    CPC分类号： C08J9/02 ,  C08J2375/00 ,  Y10S521/905 ,  Y10T428/23979 ,  Y10T428/249953

    摘要： The invention disclosed is for new improved hydrophobic polyurethane foams prepared by reacting a hydrophobic polyisocyanate reactant with large amounts of an aqueous reactant in the presence of an emulsifying agent. The resultant foams may be characterized with a broad spectrum of improved properties including load-bearing characteristics, hydrophobic properties, textural characteristics and the like.

    摘要翻译： 本发明公开了用于通过在乳化剂存在下使疏水性多异氰酸酯反应物与大量水性反应物反应制备的改进的疏水性聚氨酯泡沫。 所得泡沫体可以具有广谱的改进性能，包括承载特性，疏水性质，织构特征等。

    Protein nonadsorptive membranes for wound dressings
    4.
    发明授权
    Protein nonadsorptive membranes for wound dressings 失效
    用于伤口敷料的蛋白质非吸光膜

    公开(公告)号：US5462536A

    公开(公告)日：1995-10-31

    申请号：US91532

    申请日：1993-07-14

    申请人： James A. Braatz ,  Clifton L. Kehr ,  Timothy G. Grasel ,  William S. Letter

    发明人： James A. Braatz ,  Clifton L. Kehr ,  Timothy G. Grasel ,  William S. Letter

    IPC分类号： A61L15/26 ,  A61F13/00 ,  A61F13/02

    CPC分类号： A61L15/26

    摘要： Controlled release membranes are prepared from polyureaurethane polymer derived from prepolymer units at least 75% of which are oxyethylene-based diols or polyols having essentially all of the hydroxyl groups capped with polyisocyanate are disclosed. The membranes are characterized by their biocompatibility and resistance to nonspecific protein adsorption and are particuarly useful for delivery of proteinaceous materials in drug-delivery systems, i.e., wound dressings. Also disclosed are novel biocompatible, protein-nonadsorptive hydrated polymers and the method of producing the same.

    摘要翻译： 公开了控制释放膜，其由衍生自预聚物单元的聚脲聚氨酯聚合物制备，其中至少75％是基于氧化乙烯的二醇或基本上具有用多异氰酸酯封端的羟基的多元醇。 膜的特征在于它们的生物相容性和对非特异性蛋白质吸附的抗性，并且对于在药物递送系统（即伤口敷料）中递送蛋白质材料是特别有用的。 还公开了新的生物相容性，蛋白质 - 非吸收性水合聚合物及其制备方法。

    Biocompatible polyurea-urethane hydrated polymers
    6.
    发明授权
    Biocompatible polyurea-urethane hydrated polymers 失效
    生物相容性聚脲 - 氨基甲酸酯水合聚合物

    公开(公告)号：US5175229A

    公开(公告)日：1992-12-29

    申请号：US725699

    申请日：1991-07-03

    申请人： James A. Braatz ,  Clifton L. Kehr

    发明人： James A. Braatz ,  Clifton L. Kehr

    IPC分类号： C08G18/10 ,  C08G18/48

    CPC分类号： C08G18/4833 ,  C08G18/10 ,  C08G2210/00 ,  Y10T428/31551

    摘要： A class of hydrophilic prepolymers and hydrated polymer gels are disclosed which are characterized by their transparency, biocompatibility and resistance to nonspecific protein adsorption. At least 75%, preferably at least 90%, of the prepolymers are isocyanate-capped oxyethylene-based diols or polyols having molecular weight of about 7000-30,000. Essentially all of the hydroxyl groups of the diols or polyols are capped with polyisocyanate prior to formation of the hydrated polymer.

    摘要翻译： 公开了一类亲水预聚物和水合聚合物凝胶，其特征在于它们的透明性，生物相容性和对非特异性蛋白质吸附的抗性。 至少75％，优选至少90％的预聚物是分子量约为7000-30,000的异氰酸酯封端的氧化乙烯基二醇或多元醇。 在形成水合聚合物之前，基本上二醇或多元醇的所有羟基被多异氰酸酯封端。

    Preparation of solid polyurethane particles
    8.
    发明授权
    Preparation of solid polyurethane particles 失效
    固体聚氨酯颗粒的制备

    公开(公告)号：US4403083A

    公开(公告)日：1983-09-06

    申请号：US413294

    申请日：1982-08-31

    申请人： Nelson S. Marans ,  Clifton L. Kehr

    发明人： Nelson S. Marans ,  Clifton L. Kehr

    IPC分类号： C08G18/08 ,  C08G18/10 ,  C08G18/12 ,  C08G18/48

    CPC分类号： C08G18/4833 ,  C08G18/0866 ,  C08G18/10 ,  C08G18/12 ,  C08G2140/00 ,  C08G2150/20 ,  C08G2170/20 ,  C08G2190/00 ,  Y10S528/902 ,  Y10S528/904

    摘要： This invention relates to novel hydrophilic, crosslinked, polyurea-urethane, solid, discrete particles formed by adding in droplet form a hydrophilic prepolymer comprising an isocyanate-capped polyol or mixtures thereof wherein said polyol or mixture of polyols has a reaction functionality greater than two, the total of said polyol present having an ethylene oxide content of at least 40 weight percent, before capping to a large excess of a stirred aqueous reactant. The resultant solid particles can be molded into various shapes as desired or used for coating or adhesive applications.

    摘要翻译： 本发明涉及通过在液滴中形成包含异氰酸酯封端的多元醇或其混合物的亲水预聚物形成的新的亲水交联的聚脲 - 氨基甲酸酯，固体，离散颗粒，其中所述多元醇或多元醇混合物的反应官能度大于2， 存在的环氧乙烷含量为至少40重量％的所述多元醇的总量，在加盖到大量过量的搅拌的水性反应物之前。 所得的固体颗粒可以根据需要模制成各种形状或用于涂布或粘合剂应用。