公开(公告)号：US09439601B1

公开(公告)日：2016-09-13

申请号：US14687159

申请日：2015-04-15

申请人： Thomas V. Saliga ,  Stéphane Bibian ,  Tatjana Zikov

发明人： Thomas V. Saliga ,  Stéphane Bibian ,  Tatjana Zikov

IPC分类号： H03F1/26 ,  A61B5/00 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/0428 ,  A61B5/0496

CPC分类号： A61B5/7217 ,  A61B5/04004 ,  A61B5/0428 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/0496 ,  A61B5/4839 ,  A61B5/7221 ,  A61B5/725 ,  A61B18/1402 ,  A61B2018/00601 ,  A61B2018/00839 ,  A61B2018/1412 ,  G01R29/26

摘要： The present invention, herein is a method and apparatus that significantly limits the effect of high frequency (“HF”) interferences on acquired electro-physiological signals, such as the EEG and EMG. Preferably, this method comprises of two separate electronic circuitries and steps or electronics for processing the signals. One circuit is used to block the transmission of HF interferences to the instrumentation amplifiers. It is comprised of a front-end active filter, a low frequency electromagnetic interference (“EMI”) shield, and an isolation barrier interface which isolates the patient from earth ground. The second circuit is used to measure the difference in potential between the two isolated sides of the isolation barrier. This so-called “cross-barrier” voltage is directly representative of the interference level that the instrumentation amplifier is subjected to. This circuit is used to confirm that the acquired signals are not corrupted by the interference.

摘要翻译： 本发明是一种显着限制高频（“HF”）干扰对所获得的电生理信号如EEG和EMG的影响的方法和装置。 优选地，该方法包括用于处理信号的两个单独的电子电路和步骤或电子装置。 一个电路用于阻止HF干扰对仪表放大器的传输。 它由前端有源滤波器，低频电磁干扰（“EMI”）屏蔽以及将患者与地面隔离的隔离屏障接口组成。 第二电路用于测量隔离屏障的两个隔离侧之间的电位差。 这种所谓的“交叉屏障”电压直接代表了仪表放大器受到的干扰电平。 该电路用于确认所采集的信号没有被干扰破坏。

公开(公告)号：US08108039B2

公开(公告)日：2012-01-31

申请号：US11827906

申请日：2007-07-13

申请人： Thomas V. Saliga ,  Stephane Bibian ,  Tatjana Zikov

发明人： Thomas V. Saliga ,  Stephane Bibian ,  Tatjana Zikov

IPC分类号： A61B5/00 ,  A61B5/04

CPC分类号： A61B5/7217 ,  A61B5/04004 ,  A61B5/0428 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/0496 ,  A61B5/4839 ,  A61B5/7221 ,  A61B5/725 ,  A61B18/1402 ,  A61B2018/00601 ,  A61B2018/00839 ,  A61B2018/1412 ,  G01R29/26

摘要： The present invention, herein is a method and apparatus that significantly limits the effect of high frequency (“HF”) interferences on acquired electro-physiological signals, such as the EEG and EMG. Preferably, this method comprises of two separate electronic circuitries and steps or electronics for processing the signals. One circuit is used to block the transmission of HF interferences to the instrumentation amplifiers. It is comprised of a front-end active filter, a low frequency electromagnetic interference (“EMI”) shield, and an isolation barrier interface which isolates the patient from earth ground. The second circuit is used to measure the difference in potential between the two isolated sides of the isolation barrier. This so-called “cross-barrier” voltage is directly representative of the interference level that the instrumentation amplifier is subjected to. This circuit is used to confirm that the acquired signals are not corrupted by the interference.

摘要翻译： 本发明是一种显着限制高频（“HF”）干扰对所获得的电生理信号如EEG和EMG的影响的方法和装置。 优选地，该方法包括用于处理信号的两个单独的电子电路和步骤或电子装置。 一个电路用于阻止HF干扰对仪表放大器的传输。 它由前端有源滤波器，低频电磁干扰（“EMI”）屏蔽以及将患者与地面隔离的隔离屏障接口组成。 第二电路用于测量隔离屏障的两个隔离侧之间的电位差。 这种所谓的“交叉屏障”电压直接代表了仪表放大器受到的干扰电平。 该电路用于确认所采集的信号没有被干扰破坏。

公开(公告)号：US09050015B2

公开(公告)日：2015-06-09

申请号：US14324719

申请日：2014-07-07

申请人： Stéphane Bibian ,  Tatjana Zikov

发明人： Stéphane Bibian ,  Tatjana Zikov

IPC分类号： A61B5/0478 ,  A61B5/0492 ,  A61B5/0496 ,  A61B5/042 ,  A61B5/00 ,  A61B5/0408

CPC分类号： A61B5/0478 ,  A61B5/0408 ,  A61B5/042 ,  A61B5/0492 ,  A61B5/0496 ,  A61B5/6833 ,  A61B5/6839 ,  A61B2562/0209 ,  A61B2562/14 ,  A61B2562/242

摘要： The present invention relates to a physiological recording electrode, and, more particularly, to an EEG (electroencephalography) recording electrode that can be used without the need for numerous steps in preparing the subject's skin and the electrode itself. The invention further relates to a surface feature or penetrator with a size and shape which that will not bend or break, which limits the depth of application, and/or anchors the electrode or other device during normal application; and a packaging system comprising a well and electrolytic fluid for maintaining a coating of said electrolytic fluid on the surface feature or penetrator.

摘要翻译： 本发明涉及一种生理记录电极，更具体地说，涉及一种EEG（脑电图）记录电极，其可以在制备受试者的皮肤和电极本身时不需要许多步骤而使用。 本发明还涉及具有不会弯曲或断裂的尺寸和形状的表面特征或穿透器，这限制了施加深度，和/或在正常应用期间锚定电极或其它装置; 以及包括井和电解液的包装系统，用于将所述电解液的涂层保持在表面特征或穿透器上。

公开(公告)号：US11872045B1

公开(公告)日：2024-01-16

申请号：US17580773

申请日：2022-01-21

申请人： NeuroWave Systems Inc.

发明人： Stéphane Bibian ,  Tatjana Zikov

IPC分类号： A61B5/25 ,  A61B5/291 ,  A61B5/00 ,  A61B5/378

CPC分类号： A61B5/291 ,  A61B5/4094 ,  A61B5/684 ,  A61B5/6814 ,  A61B5/0006 ,  A61B5/378 ,  A61B5/4064

摘要： Electrodes for use in electroencephalographic recording, including consciousness and seizure monitoring applications, have novel features that speed, facilitate or enforce proper placement of the electrodes, including aligning tabs and arrowed aligning juts, color coding, and an insulating bridge between reference and ground electrodes which ensures a safe application distance between the conductive regions of the two electrodes in the event of cardiac defibrillation or to prevent shorting between the adjacent electrodes by preventing the conductive path to be shared. A method of using a set of four such electrodes is also disclosed.

公开(公告)号：US08838226B2

公开(公告)日：2014-09-16

申请号：US12628568

申请日：2009-12-01

申请人： Stéphane Bibian ,  Tatjana Zikov

发明人： Stéphane Bibian ,  Tatjana Zikov

IPC分类号： A61B5/0476 ,  A61B5/00

CPC分类号： A61B5/0476 ,  A61B5/4064 ,  A61B5/4082 ,  A61B5/4821 ,  A61B5/6843 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7225 ,  A61B5/7257 ,  A61B5/726 ,  A61M5/1723

摘要： The present invention relates to a quantitative electroencephalogram (QEEG) monitor and system capable of monitoring and displaying simultaneously neuropathological characteristic and activity of both sides of a subject's brain. The methods include various indices and examination of differences in these indices by which neurophysiological conditions or problems can be identified and treated. These methods, and the systems and devices using these methods preferably can be used for identifying these neurophysiological conditions or brain dysfunction with monitors and methods for seizure detection, for sedation monitoring, for anesthesia monitoring, and the like. These bilateral brain monitoring methods and systems, and the devices using these methods can be used by individuals or clinicians with little or no training in signal analysis or processing. These bilateral monitoring methods can also be used in a range of applications.

摘要翻译： 本发明涉及一种能够同时监测和显示受试者脑部两侧的神经病理特征和活动的定量脑电图（QEEG）监测器和系统。 这些方法包括各种指标和检查这些指标的差异，通过这些指标可以识别和治疗神经生理学条件或问题。 使用这些方法的这些方法以及使用这些方法的系统和装置优选地可以用于通过用于缉获检测的监测器和方法来鉴别这些神经生理学状况或脑功能障碍，用于镇静监测，用于麻醉监测等。 这些双侧大脑监测方法和系统以及使用这些方法的装置可以由信号分析或处理中很少或根本没有训练的个人或临床医生使用。 这些双边监测方法也可用于一系列应用。

公开(公告)号：US08473043B1

公开(公告)日：2013-06-25

申请号：US11454485

申请日：2006-06-16

申请人： Mo Modarres

发明人： Mo Modarres

IPC分类号： A61B5/04

CPC分类号： A61B5/168 ,  A61B5/0006 ,  A61B5/04012 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/048 ,  A61B5/0484 ,  A61B5/04842 ,  A61B5/04845 ,  A61B5/4088 ,  A61B5/4806 ,  A61B5/4848

摘要： A new neuro-behavioral test with analysis algorithms has been developed for use in screening individuals for attention deficit hyperactivity disorder (ADHD) and for the quantitative evaluation of ADHD medication/therapy in diagnosed patients. This technique combines a 15 minute auditory-based test of attention with simultaneous EEG monitoring by a wireless, portable data acquisition device. This system acquires both behavioral response (i.e., reaction times to target stimuli, as well as errors of omission/commission) and EEG waveforms. All of the data is simultaneously processed by the algorithms to produce several representative indices. These indices are then combined to produce an overall neuro-behavioral index that represents the degree by which both “behavioral” and “EEG” attention is maintained throughout the test.

摘要翻译： 已经开发了一种新的具有分析算法的神经行为测试，用于筛选个体的注意缺陷多动障碍（ADHD）和用于诊断患者的ADHD药物/治疗的定量评估。 该技术将基于听觉的15分钟听觉测试与无线便携式数据采集设备的同步脑电监测相结合。 该系统获取行为响应（即，针对刺激的反应时间，以及省略/调试的错误）和EEG波形。 所有数据由算法同时处理，以产生几个代表性的索引。 然后将这些指数组合以产生整体神经行为指数，其表示在整个测试中保持“行为”和“脑电”注意力的程度。