公开(公告)号：US10647621B2

公开(公告)日：2020-05-12

申请号：US15780078

申请日：2016-11-30

申请人： Adelaide Research and Innovation ,  Flinders University of South Australia ,  University of Canterbury ,  University of South Australia

发明人： Gregory F Metha ,  Gunther Andersson ,  Vladimir Golovko ,  Thomas Nann

IPC分类号： C07C1/12 ,  B01J23/52 ,  C07C29/157 ,  B01J21/06 ,  B01J21/18 ,  B01J23/46 ,  B01J35/00 ,  B01J31/22 ,  B01J23/42 ,  B01J31/24 ,  C10G2/00 ,  C01B3/04 ,  B01J37/16 ,  C01B3/06 ,  C07C9/04 ,  C07C31/04 ,  B01J37/03

摘要： A method for the production of hydrocarbon(s), such as methane, substituted hydrocarbons, such as methanol, or the production of hydrogen, the method comprising the steps of contacting a first catalyst with water in order to photocatalyse the splitting of at least some of the water into hydrogen and oxygen; and contacting a second catalyst with a gas stream comprising carbon dioxide and at least some of the hydrogen produced from step (a) in order to photocatalyse the reaction between the hydrogen and carbon dioxide to produce hydrocarbon(s), such as methane, and/or substituted hydrocarbons, such as methanol. In an embodiment, the catalyst comprises gold and or ruthenium nanoclusters supported on a substrate.

公开(公告)号：US20070147702A1

公开(公告)日：2007-06-28

申请号：US11685719

申请日：2007-03-13

申请人： Paul Scoullar ,  Robin Evans

发明人： Paul Scoullar ,  Robin Evans

IPC分类号： G06K9/36

CPC分类号： G01T1/171 ,  G01T1/202

摘要： A method and apparatus for resolving individual signals in detector output data, the method comprising determining a signal form of signals present in the data, making parameter estimates of one or more parameters of the signals, wherein the one or more parameters comprise at least signal temporal position, and determining the energy of the signals from at least the form and the parameter estimates.

摘要翻译： 一种用于解决检测器输出数据中的各个信号的方法和装置，所述方法包括确定存在于数据中的信号的信号形式，对信号的一个或多个参数进行参数估计，其中所述一个或多个参数至少包括信号时间 位置，以及至少从形式和参数估计确定信号的能量。

公开(公告)号：US20200072842A1

公开(公告)日：2020-03-05

申请号：US16604990

申请日：2018-04-12

申请人： University of South Australia ,  Flinders University of South Australia

发明人： Krasimir Atanasov Vasilev ,  Melanie Macgregor ,  Jonathan Gleadle ,  Jordan Li

IPC分类号： G01N33/574 ,  G01N33/569 ,  G01N33/543

摘要： A device for selective capture of target bladder cancer cells from urine or a urine derived fluid is provided. The device comprises a substrate having one or more cell capture surfaces, each cell capture surface comprising a functionalized film on the substrate and one or more target bladder cancer cell selective binding agents covalently bound to the functionalized film.

公开(公告)号：US10004660B2

公开(公告)日：2018-06-26

申请号：US14646535

申请日：2013-11-22

申请人： FLINDERS UNIVERSITY OF SOUTH AUSTRALIA ,  UNIVERSITY OF SOUTH AUSTRALIA ,  WOMEN'S AND CHILDREN'S HEALTH NETWORK, INC.

发明人： David Anthony Hobbs ,  Susan Loris Hillier ,  Remo Nunzio Russo ,  Alexander William Walker ,  Max Bristow Hughes ,  Thomas Samuel Whitby

IPC分类号： A61H23/00 ,  A61H39/00 ,  A63F13/211 ,  A63F13/24 ,  A63F13/285 ,  A61H23/02 ,  A61H1/02 ,  A61B5/00

CPC分类号： A61H23/00 ,  A61B5/4047 ,  A61B5/4827 ,  A61B5/6896 ,  A61B5/6897 ,  A61B2562/0257 ,  A61H1/0288 ,  A61H23/02 ,  A61H39/007 ,  A61H2201/0165 ,  A61H2201/1635 ,  A61H2201/1695 ,  A61H2201/5002 ,  A61H2201/5005 ,  A61H2201/5007 ,  A61H2201/5084 ,  A61H2205/065 ,  A61H2205/067 ,  A63F13/211 ,  A63F13/24 ,  A63F13/285

摘要： A method for treating patients with sensor agnosia is described that uses a gaming system with a specialised two handed game controller that can provide isolated haptic feedback to the patient's hand that has the greatest sensory agnosia. The controller is designed to be easy to use for patients with limited dexterity and requires the user to use both hands to control the controller. The gaming system provides a range of interactive computer games that provide contextually relevant haptic feedback of varying durations and intensities. Haptic feedback is provided in response to events in a game, and whilst the controller requires two hands, each hand is vibrationally isolated so that haptic feedback is only provided to the desired hand. The system logs usage statistics of the patient and these can be sent back to a clinician for analysis. The system and controller is particularly suitable for children with Cerebral Palsy, but may be used to treat patients with sensory agnosia due to range of conditions.

公开(公告)号：US20230071171A1

公开(公告)日：2023-03-09

申请号：US17869356

申请日：2022-07-20

申请人： The Flinders University of South Australia

发明人： Christopher Milton Mathew FRANCO ,  Hoang Xuyen LE ,  Ross Alexander BALLARD

IPC分类号： A01N63/28 ,  A01N63/20 ,  C12N15/82 ,  A01H3/00 ,  C12N1/20 ,  C12R1/465

摘要： The present invention relates to methods for enhancing at least one growth parameter of a leguminous plant via co-inoculation of a leguminous plant with at least one rhizobial microorganism together with at least one actinobacterial microorganism. In further aspects, the present invention also relates to leguminous plants co-inoculated with at least one rhizobial microorganism together with at least one actinobacterial microorganism, as well as specific actinobacterial strains and inoculant compositions which are useful in accordance with the present invention.

公开(公告)号：US20230002502A1

公开(公告)日：2023-01-05

申请号：US17779908

申请日：2020-11-26

申请人： South Australian Health and Medical Research Institute Limited ,  The Flinders University of South Australia

发明人： David John Lynn ,  Stephen James Blake

IPC分类号： C07K16/28 ,  C07K16/24

摘要： The present disclosure relates to methods and products for reducing side effects associated with immunotherapy using immune agonist antibodies. In certain embodiments, the present disclosure provides a method of reducing one or more side effects associated with immunotherapy using an immune agonist antibody alone, or in combination with an immune checkpoint inhibitor, in a subject suffering from a cancer, the method comprising modifying the gut microbiota in the subject and thereby reducing the one or more side effects associated with the immunotherapy in the subject.

公开(公告)号：US11261496B2

公开(公告)日：2022-03-01

申请号：US15794270

申请日：2018-01-23

申请人： UNIVERSITY OF SOUTH AUSTRALIA

发明人： Doug Brooks ,  Emma Parkinson-Lawrence ,  Ian R. D. Johnson ,  Lisa Butler

IPC分类号： G01N33/574 ,  C12Q1/6886 ,  A61P35/00 ,  C07K16/30 ,  C07K14/47 ,  C07K14/705 ,  C07K16/18 ,  C07K16/28 ,  A61N5/10

摘要： Methods for detecting a prostate cancer in a subject comprise detecting a marker selected from an endosomal associated marker and/or a lysosomal associated marker from the subject.

公开(公告)号：US20210213053A1

公开(公告)日：2021-07-15

申请号：US17059221

申请日：2019-05-29

申请人： The Flinders University of South Australia ,  The University of Melbourne

发明人： Kelton Paul Tremellen ,  David K. Gardner ,  Alexandra J. Harvey

IPC分类号： A61K33/34 ,  A61K33/30 ,  A61K47/38 ,  A61K47/10 ,  A61K9/08 ,  A61K9/14 ,  A61K9/06 ,  A61B17/43 ,  A61B17/435

摘要： A method of enhancing embryo implantation in a subject is disclosed which comprises administering to the uterine cavity of the subject a formulation comprising copper and/or zinc in an amount effective to stimulate endometrial production of leukaemia inhibitory factor (LIF) and/or vascular endothelial growth factor (VEGF). Alternatively, a device may be inserted into the uterine cavity of the subject, wherein the device comprises copper and/or zinc, for a period of time that is effective to stimulate endometrial production of LIF and/or VEGF. The method is suitable for use with women undergoing treatment by any of the assisted reproductive technologies, such as those involving the transfer of embryos such as in vitro fertilisation (IVF) and variants including IVF-ICSI (intracytoplasmic sperm injection) and in vitro maturation (IVM) treatments, as well as intrauterine-insemination (IUI) therapy. However, the method is also applicable for women wanting to improve their prospects of pregnancy through natural conception.

公开(公告)号：US10596187B2

公开(公告)日：2020-03-24

申请号：US15034965

申请日：2014-11-07

申请人： Yale University ,  Flinders University of South Australia ,  Balakrishnan Siddartha Ramakrishna

发明人： Balakrishnan Siddartha Ramakrishna ,  Graeme Paul Young ,  Ian Lewis Brown ,  Henry Joseph Binder

IPC分类号： A61K33/00 ,  A23L2/38 ,  A61K31/718 ,  A61K33/14 ,  A61K47/36 ,  A61K9/00 ,  A23L2/52 ,  A61K33/30 ,  A61K33/34 ,  A61K33/06 ,  A23L33/105 ,  A23L33/16 ,  A23L29/212 ,  A23L33/10 ,  A23L33/21 ,  A23L29/269 ,  A23L29/238 ,  A23L29/256 ,  A23L29/231 ,  A23L29/25 ,  A23L29/281 ,  A61K31/194 ,  A61K31/7004

摘要： Provided herein are compositions, for example: oral rehydration compositions, beverages, food items, methods and uses, which utilise resistant starch to prevent or treat dehydration, including dehydration which is caused by diarrhoea. Beverages, food items and oral rehydration solutions including a resistant starch, which are suitable for aiding in the maintenance and restoration of hydration levels in individuals undertaking physical activities, including sports, are also disclosed.

公开(公告)号：US20200079858A1

公开(公告)日：2020-03-12

申请号：US16493845

申请日：2018-03-14

申请人： UNIVERSITY OF SOUTH AUSTRALIA ,  CENTRAL ADELAIDE LOCAL HEALTH NETWORK INC. ,  SOCIETE DE COMMERCIALISATION DES PRODUITS DE LA RECHERCHE APPLIQUEE SOCPRA SOCPRA SCIENCES SANTE ET

发明人： Jeffrey Victor LEYTON ,  Eric MARSAULT ,  Simon BEAUDOIN ,  Pierre-Luc BOUDREAULT ,  Marc-André BONIN ,  Angel LOPEZ

IPC分类号： C07K16/28 ,  G01N33/574 ,  A61K47/54 ,  A61K47/68 ,  A61K51/04 ,  A61K51/10

摘要： The present description relates to a conjugated anti-interleukin-5 receptor α-subunit (IL-5Rα) compound comprising cholic acid (ChAc) or a variant thereof, the ChAc conjugated to a non-cell penetrating peptide comprising a nuclear localization sequence (NLS) conjugated to an anti-interleukin-5 receptor α-subunit (IL-5Rα) compound and further conjugated to chemotherapeutic agent and/or a radionuclide.