-
1.发明授权公开(公告)号：US12062994B2
公开(公告)日：2024-08-13
申请号：US17381443
申请日：2021-07-21
发明人： David Maier , Marco Zimmer , Nejila Parspour
IPC分类号： H02P6/15 , H02J50/10 , H02M7/217 , H02P9/12 , H02P25/022
CPC分类号： H02M7/217 , H02J50/10 , H02P25/022
摘要： The present invention relates to a circuit arrangement having an active rectifier circuit, in particular on a secondary side of an inductive energy transmission path. The circuit arrangement has a half or full bridge of power transistors for rectifying an AC voltage induced in an input inductor of the circuit arrangement. The power transistors are connected to the input inductor in such a way that an auxiliary voltage is split off from the induced AC voltage for switching the power transistors. As a result, even large currents, which result in a low output voltage, can be transmitted without endangering the operation of the rectifier circuit.
-
公开(公告)号：US20240194367A1
公开(公告)日：2024-06-13
申请号：US18530288
申请日：2023-12-06
发明人： Florian MEINERT , Philipp ILZHOEFER , Tilman PFAU , Martin TRAUB , Martin ADAMS , Hans-Dieter HOFFMANN
CPC分类号： G21K1/003 , G21K1/06 , G21K2201/067
摘要： The present invention relates to a device (10) for generating optical tweezers comprising a laser beam source (11) for generating a laser beam (12) and at least one acousto-optic deflector (13) for generating an array (15) of partial beams (14) of the laser beam (12), wherein the array (15) comprises rows (15c). The device (10) further comprises a stepped mirror unit (16) comprising at least a first stepped mirror (25) for reducing a row distance (15d) of the partial beams (14) of the array (15), wherein the first stepped mirror (25) comprises mirrors (30), a stepped distance (25a) between adjacent mirrors (30) and a stepped height (25b).
-
公开(公告)号：US11851489B2
公开(公告)日：2023-12-26
申请号：US16615536
申请日：2018-06-01
CPC分类号： C07K16/2809 , C07K16/2878 , C07K16/30 , C07K16/32 , C07K16/40 , A61K38/00 , C07K2317/31 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/528 , C07K2317/53 , C07K2317/622 , C07K2317/76 , C07K2317/94
摘要： The present invention provides a protein complex comprising heterodimerizing regions HRI and HRII, each comprised of antiparallel β-strands and intervening regions wherein HRI and HRII are each interspersed fusion proteins of two human constant regions of an immunoglobulin or immunoglobulin-like proteins. The present invention also provides nucleic acid molecules comprising a sequence encoding said protein complexes and vectors comprising the nucleic acid. The present invention also provides the protein complex, the nucleic acid and the vector for use as a medicament. The present invention further provides a method of determining the amino acid sequence of HRI and/or of the amino acid sequence of HRII. The present invention also provides a method of producing amino acid chains of HRI and/or amino acid chains of HRII. The present invention further provides the protein complex for use in the N prophylaxis, treatment or diagnosis of a disorder or a disease.
-
公开(公告)号：US20230182929A1
公开(公告)日：2023-06-15
申请号：US18077291
申请日：2022-12-08
CPC分类号： B64G1/405 , H05H1/54 , G01R33/34076 , H05H2245/00 , B33Y80/00
摘要： A plasma thruster comprises a cylindrical discharge channel (1), an injector (4), a RF antenna surrounding the discharge channel (1) and a device (3) for generating an axial static magnetic field in the discharge channel (1). The RF antenna is a cylindrical birdcage antenna (2) formed of several electrically conductive parallel legs (10) connected by two end rings (11) including capacitors (12) between adjacent legs (10) in each case. The two end rings (11) with the capacitors (12) are formed on two printed circuit boards (14) to which the legs (10) are attached, said printed circuit boards (14) having a through opening for the discharge channel (1). The antenna maximizes electrical coupling efficiency and provides resulting electromagnetic fields for quasi-neutral plasma acceleration along with the magnetic field effect provided by the externally applied magnetic field. This plasma thruster allows an easy upscaling or downscaling due to the printed circuit boards and is particularly suitable for low power applications like propulsion for smaller spacecrafts or satellites.
-
5.发明申请公开(公告)号：US20210395323A1
公开(公告)日：2021-12-23
申请号：US17465186
申请日：2021-09-02
IPC分类号： C07K14/525
摘要： The present invention relates to a tumor necrosis factor receptor (TNFR) binding protein complex comprising 12 or more N protein ligands (PLs) that specifically bind to the extracellular part of the same TNFR. Preferably, the TNFR binding protein complex binds to the extracellular part of TNFR2. Preferably, the TNFR binding protein complex of the present invention further comprises a two or more polymerization domains (PD).
-
公开(公告)号：US11008402B2
公开(公告)日：2021-05-18
申请号：US16326864
申请日：2017-09-15
发明人： Roland Kontermann , Lisa Schmitt , Meike Hutt , Oliver Seifert , Monilola Olayioye , Michael Hust , Stefan Dübel , Jonas Zantow
摘要： The invention provides an antigen-binding protein that specifically binds to a conformational epitope formed by domain III & IV of human epidermal growth factor receptor 3 (HER3) and antigen-binding proteins which compete therewith for binding, as well as fusion protein or conjugate comprising these. The invention also provides nucleic acid molecule comprising a sequence encoding said antigen binding proteins, vectors comprising the nucleic acid, and cells and pharmaceuticals comprising the antigen binding protein, the fusion protein, the nucleic acid, or the vector. The invention also provides the antigen binding protein, the fusion protein or conjugate, the nucleic acid, the vector, the cell, or the pharmaceutical for use as a medicament. The invention further provides a method of inhibiting tumor growth or treating cancer, comprising administering a therapeutically effective amount of the antigen binding protein, the fusion protein or conjugate, the nucleic acid, the vector, the cell, or the pharmaceutical.
-
公开(公告)号：US20210002376A1
公开(公告)日：2021-01-07
申请号：US16982714
申请日：2018-03-22
摘要： The present invention relates to a modular multivalent antigen-binding protein complex, use of the antigen-binding protein complex in medicine and use of the antigen-binding protein complex in the prophylaxis, treatment or diagnosis of a disorder or disease.
-
8.发明授权公开(公告)号：US10689452B2
公开(公告)日：2020-06-23
申请号：US16091456
申请日：2017-04-04
发明人： Roland Kontermann , Klaus Pfizenmaier , Fabian Richter , Kirstin Zettlitz , Peter Scheurich , Andreas Herrmann
摘要： The invention provides for an inhibitor of the huTNFRI receptor which is a human or humanized antibody construct that monovalently recognizes huTNFRI through an antigen-binding moiety, which is characterized by specific CDR sequences, a pharmaceutical preparation thereof, method of producing the inhibitor and the medical use of the inhibitor.
-
公开(公告)号：US10574024B2
公开(公告)日：2020-02-25
申请号：US15494102
申请日：2017-04-21
摘要： The present invention relates to an optical module configured to be optically coupleable to a laser amplifier module, the optical module comprising an inner optical element having a plurality of M inner reflective elements arranged around a center of the inner optical element; and a plurality of N outer reflective elements arranged around the inner optical element, the plurality of N outer reflective elements being configured to face the inner optical element, wherein the plurality of M inner reflective elements and the plurality of N outer reflective elements are configured to provide an optical path for a laser beam.
-
公开(公告)号：US10137596B2
公开(公告)日：2018-11-27
申请号：US15322489
申请日：2015-06-16
发明人： Hanaa Dahy , Jan Knippers
摘要： The present invention provides a flexible high-density fiberboard which is essentially free of formaldehyde and isocyanates and comprises 70 to 90% by weight of straw fibers, and 30 to 10% by weight of a thermoplastic elastomer and one or more optional additive(s). Furthermore, the present invention provides a method for manufacturing such a flexible high-density fiberboard comprising the steps of providing straw fibers, providing a thermoplastic elastomer in powder form, optionally providing one or more additive(s), dry mixing the straw fibers, the thermoplastic elastomer powder and optionally the one or more additive(s), such that a mixture comprising 70 to 90% by weight of the straw fibers, and 30 to 10% by weight of the thermoplastic elastomer and one or more of the optional additive(s) is obtained, extruding the obtained mixture at a temperature such that the thermoplastic elastomer powder is in a molten state, and pressing the extruded mixture.
-
-
-
-
-
-
-
-
-
搜索结果
72 条记录 (耗时 0.022 秒)
