公开(公告)号：US11129655B2

公开(公告)日：2021-09-28

申请号：US16515477

申请日：2019-07-18

申请人： SPINEFRONTIER, INC

发明人： Jeremy Crossgrove ,  Oscar Herrera ,  Michael Emery ,  Joshua Finkel ,  Kyle Woodard ,  Kingsley R. Chin

IPC分类号： A61B17/86 ,  A61F2/30

摘要： A bone fusing implant device includes an elongated body extending along a longitudinal direction. The elongated body includes a first segment having an outer surface with cortical threads, a second segment having an outer surface with cancellous threads, a top segment and a bottom segment. The first segment is adjacent to the second segment along the longitudinal direction and is configured to engage a cortical bone with the cortical threads and the second segment is configured to engage a cancellous bone with the cancellous threads. The elongated body has one or more elongated fusing gutters extending along the longitudinal direction on an outer surface of the elongated body covering the first and second segments, a central opening extending along the longitudinal direction through the elongated body's center and one or more through-openings that extend horizontally and intersect with the one or more fusing gutters.

公开(公告)号：US10983058B1

公开(公告)日：2021-04-20

申请号：US16355152

申请日：2019-03-15

申请人： Amplyus LLC

发明人： Ezequiel Alvarez Saavedra ,  Sebastian Kraves

IPC分类号： G01N21/64

摘要： A device and method are described for the naked eye visualization of fluorophores. The device has a light source capable of exciting fluorophores, a rack to receive one or more fluorophores and a window through which test tubes can be observed. The method provides a means for inferring the conformational state of molecules from the amount of fluorescence emitted by the fluorophores.

公开(公告)号：US10772830B1

公开(公告)日：2020-09-15

申请号：US16830883

申请日：2020-03-26

申请人： Evangelos Karavas ,  Efthimios Koutris ,  Vasiliki Samara ,  Ioanna Koutri ,  Anastasia Kalaskani ,  Andreas Kakouris ,  George Gotzamanis

发明人： Evangelos Karavas ,  Efthimios Koutris ,  Vasiliki Samara ,  Ioanna Koutri ,  Anastasia Kalaskani ,  Andreas Kakouris ,  George Gotzamanis

IPC分类号： A61K31/5575 ,  A61K47/00 ,  A61K47/12 ,  A61K9/00 ,  A61K47/26 ,  A61K47/10 ,  A61K47/38 ,  A61K9/08 ,  A61K31/165 ,  A61K31/5377 ,  A61K31/382 ,  A61K47/02

摘要： The present invention relates to a preservative-free, aqueous solution in the form of eye drops packed in a container that ensures stability of the product, ideal eye drop volume and reduced drop volume variability and provides efficient dispensing.

公开(公告)号：US10677919B2

公开(公告)日：2020-06-09

申请号：US15938363

申请日：2018-03-28

申请人： NANJING HYDRAULIC RESEARCH INSTITUTE

发明人： Yan Xiang ,  Zhuo Li ,  Jinbao Sheng ,  Yunqing Tang ,  Chengdong Liu ,  Guangya Fan ,  Haifei Sha ,  Xiaolei Zhan ,  Kai Zhang ,  Guangze Shen

IPC分类号： G01S15/08 ,  B63G8/00 ,  B63G8/24 ,  E02B7/00 ,  G05D1/02 ,  E02B7/04 ,  G01S15/88 ,  G01S15/46 ,  G01C21/20 ,  G05D1/04 ,  E02B17/00

摘要： The present invention provides a self-positioning system of a deepwater underwater robot of an irregular dam surface of a reservoir, including cross reflection metal plates arranged on the irregular dam surface, and an underwater robot provided with a control motherboard, a water level indicator and a sonar system, wherein the water level indicator and the sonar system are respectively connected with the control motherboard, and the control motherboard is connected with a computer via a cable. The cross reflection metal plate has known coordinates and has four quadrants. A sonar signal emitted by the sonar system is reflected by the cross reflection metal plate to generate sonar reflection signals of four quadrants, and the sonar signals in the effective quadrants correspond to known coordinate parameters of the cross reflection metal plate so as to obtain the horizontal distance between the underwater robot and the irregular dam surface. The water level indicator is used for calculating the vertical position of the underwater robot. The computer calculates accurate positioning of the underwater robot according to the horizontal position and the vertical position. The present invention has the beneficial effects of being able to accurately obtain the positioning coordinates of the underwater robot in the deepwater of the irregular dam surface of the reservoir.

公开(公告)号：US10672594B2

公开(公告)日：2020-06-02

申请号：US15797017

申请日：2017-10-30

申请人： Ontos Equipment Systems, Inc.

发明人： Robert Emmett Hughlett ,  Matthew Sheldon Phillips ,  Eric Frank Schulte ,  Michael Dow Stead

IPC分类号： B32B41/00 ,  H01J37/32

摘要： An atmospheric pressure plasma system includes an atmospheric pressure plasma source that generates a glow discharge-type plasma. The atmospheric pressure plasma source comprises a plasma head, a heating element and an active cooling element and the heating element and active cooling element control the plasma head temperature to a set-point temperature independent of variations in plasma generating power or plasma power ON/OFF status.

公开(公告)号：US10258994B2

公开(公告)日：2019-04-16

申请号：US14422030

申请日：2013-08-16

申请人： MADDISON MORGAN & BAILEY LIMITED

发明人： Philip Andrew Cooke

IPC分类号： B02C19/00 ,  B29B17/02 ,  B26F3/00 ,  B29B17/04 ,  B09B5/00 ,  B29L31/58 ,  B29L31/00

摘要： Method and apparatus for deconstructing, cutting, shredding or disintegrating a mattress, sofa, car seat or similar items with steel or metal sub frames by the use of high pressure water jets whereby the mattress, sofa, car seat or the like is compressed and then deconstructed while compressed by the use of high pressure water jets.

公开(公告)号：US09943484B2

公开(公告)日：2018-04-17

申请号：US14898415

申请日：2014-06-18

申请人： PHARMATHEN S.A.

发明人： Evangelos Karavas ,  Efthymios Koutris ,  Sotiria Haitidou ,  Theofanis Mantourlias ,  Georgia Papanikolaou

IPC分类号： A61K9/14 ,  A61K9/16 ,  C08J3/12 ,  C08J3/14 ,  A61K31/519

CPC分类号： A61K9/1682 ,  A61K9/1647 ,  A61K9/1694 ,  A61K31/519 ,  C08J3/12 ,  C08J3/14 ,  C08J2300/16 ,  C08J2367/04

摘要： The present invention relates to preparation of biodegradable microparticles formed from polylactide-polyglycolide copolymers (PLGA) polymer and how to achieve sigmoidal release of active pharmaceutical compound from the microparticles. In particular, the present invention relates to emulsification of an inner/oil phase to an outer/water phase followed by quenching and a single drying step for the preparation of microparticles having a preferred release profile of preferably basic/nucleophilic compounds such as risperidone. Alternatively the present invention is also suitable for hydrophobic compounds that have poor water-solubility and a high drug loading of >20% w/w is required. The release profile can be controlled by adjusting the degree of saturation of the outer/water phase with the organic solvent used in the inner/oil phase, the polymer concentration of the inner/oil phase and the temperature at the quenching step. In particular, an initial lag phase and a substantially sigmoidal release profile are achieved by using an outer aqueous phase over saturated with the solvent used in the inner phase at emulsification step, in combination with a low temperature during quenching.

公开(公告)号：US09936982B2

公开(公告)日：2018-04-10

申请号：US14089293

申请日：2013-11-25

申请人： Matthew Ibarra ,  Craig Henshaw ,  Jeremy Crossgrove ,  Aaron Ricica ,  Elizabeth Elidias ,  Carin Campbell

发明人： Matthew Ibarra ,  Craig Henshaw ,  Jeremy Crossgrove ,  Aaron Ricica ,  Elizabeth Elidias ,  Carin Campbell

IPC分类号： A61B17/70

CPC分类号： A61B17/7052

摘要： A connector assembly for translateral linking of bilateral spinal fixation rods includes first and second components. The first component has an elongated body having first and second ends, and the first end of the first component is configured to connect to a first spinal fixation rod. The second component has an elongated body having first and second ends, and the first end of the second component is configured to connect to a second spinal fixation rod. The second end of the first component is configured to be slidably connected to the second end of the second component.

公开(公告)号：US09909997B2

公开(公告)日：2018-03-06

申请号：US14422081

申请日：2013-08-23

申请人： LUOYANG LANDGLASS TECHNOLOGY CO., LTD.

发明人： Yanbing Li ,  Bin Liu

IPC分类号： H04N7/18 ,  G01N21/958 ,  G01B11/25 ,  G01N21/896 ,  C03B35/00 ,  G01B11/06 ,  G01B11/16 ,  G01N21/88 ,  H04N7/00 ,  G01N21/49

CPC分类号： G01N21/958 ,  C03B35/00 ,  G01B11/0691 ,  G01B11/167 ,  G01B11/2518 ,  G01B11/2522 ,  G01N21/49 ,  G01N21/8806 ,  G01N21/896 ,  G01N2201/06113 ,  G01N2201/103 ,  H04N7/00

摘要： A detection system based on modulation of line structured laser image of glass includes a processing section, a control system, and roller conveying mechanisms. Detection mechanism provided over entrance of the processing section includes shell and camera with laser which emits beam on the surface of the glass in the gap between sliding rollers. Focal plane of the camera corresponds to the beam irradiation surface, and signal output terminal of the camera is connected with the control system in such a way that when glass passes the detection area, laser irradiates the glass surface and the line structured laser is modulated based on the glass to form laser modulation image with distribution of light and shade, staggered movement direction, or distorted laser lines. The camera transmits the captured glass information and parameters to the control system.

公开(公告)号：USD806797S1

公开(公告)日：2018-01-02

申请号：US29575029

申请日：2016-08-22

申请人： Mieczyslaw Irek

设计人： Mieczyslaw Irek