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    CO-METABOLISM OF FRUCTOSE AND GLUCOSE IN MICROBIAL PRODUCTION STRAINS
    4.
    发明申请
    CO-METABOLISM OF FRUCTOSE AND GLUCOSE IN MICROBIAL PRODUCTION STRAINS 有权
    葡萄糖和葡萄糖在微生物生产菌株中的CO代谢

    公开(公告)号：US20110256598A1

    公开(公告)日：2011-10-20

    申请号：US12906537

    申请日：2010-10-18

    申请人： Andrew C. Eliot ,  Anthony A. Gatenby ,  John S. Chapman

    发明人： Andrew C. Eliot ,  Anthony A. Gatenby ,  John S. Chapman

    IPC分类号： C12N1/21 ,  C12P7/20 ,  C12P7/42 ,  C12P7/18

    CPC分类号： C07K14/245 ,  C12P7/18 ,  C12P7/20 ,  C12P7/42

    摘要： Recombinant microorganisms having an improved ability to co-metabolize in medium both fructose and glucose are described. The recombinant microorganisms comprise a promoter operably linked to a native or non-native nucleotide sequence that encodes a fucose:H+ symporter polypeptide. The recombinant microorganisms are useful for the production of a variety of products including glycerol and glycerol derivatives such as 1,3-propanediol and 3-hydroxypropionic acid.

    摘要翻译： 描述了具有改善在培养基中同时代谢果糖和葡萄糖的能力的重组微生物。 重组微生物包含与天然或非天然核苷酸序列可操作地连接的启动子，其编码岩藻糖：H +对映体多肽。 重组微生物可用于生产各种产物，包括甘油和甘油衍生物如1,3-丙二醇和3-羟基丙酸。

    RECOMBINANT BACTERIA FOR PRODUCING GLYCEROL AND GLYCEROL-DERIVED PRODUCTS FROM SUCROSE
    6.
    发明申请
    RECOMBINANT BACTERIA FOR PRODUCING GLYCEROL AND GLYCEROL-DERIVED PRODUCTS FROM SUCROSE 审中-公开
    用于生产来自西红柿的甘油和甘油衍生产品的重组细菌

    公开(公告)号：US20110136190A1

    公开(公告)日：2011-06-09

    申请号：US12943334

    申请日：2010-11-10

    申请人： ANDREW C. ELIOT ,  Anthony A. Gatenby ,  Tina K. Van Dyk

    发明人： ANDREW C. ELIOT ,  Anthony A. Gatenby ,  Tina K. Van Dyk

    IPC分类号： C12N1/21 ,  C12P7/20 ,  C12P7/18 ,  C12P7/42

    CPC分类号： C12N9/2451 ,  C12N9/1205 ,  C12P7/18 ,  C12P7/20 ,  C12P7/42

    摘要： Recombinant bacteria capable of producing glycerol and glycerol-derived products from sucrose are described. The recombinant bacteria comprise in their genome or on at least one recombinant construct: a nucleotide sequence encoding a polypeptide having sucrose transporter activity; a nucleotide sequence encoding a polypeptide having fructokinase activity; and a nucleotide sequence encoding a polypeptide having sucrose hydrolase activity. These nucleotide sequences are each operably linked to the same or a different promoter. These recombinant bacteria are capable of metabolizing sucrose to produce glycerol and/or glycerol-derived products such as 1,3-propanediol and 3-hydroxypropionic acid.

    摘要翻译： 描述了能够从蔗糖生产甘油和甘油衍生产物的重组细菌。 重组细菌在其基因组或至少一种重组构建物中包含：编码具有蔗糖转运蛋白活性的多肽的核苷酸序列; 编码具有果糖激酶活性的多肽的核苷酸序列; 以及编码具有蔗糖水解酶活性的多肽的核苷酸序列。 这些核苷酸序列各自可操作地连接到相同或不同的启动子。 这些重组细菌能够代谢蔗糖以产生甘油和/或甘油衍生产物如1,3-丙二醇和3-羟基丙酸。