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公开(公告)号:US20140018589A1
公开(公告)日:2014-01-16
申请号:US13936870
申请日:2013-07-08
申请人: Rahul Iyer , Alex Tkachenko , Sam Weinberger , Erik Scher , Guido Radaelli , Hatem Harraz
发明人: Rahul Iyer , Alex Tkachenko , Sam Weinberger , Erik Scher , Guido Radaelli , Hatem Harraz
IPC分类号: C07C2/82
CPC分类号: C07C2/82 , B01J8/02 , B01J8/04 , C07C2/06 , C07C2/84 , C10G9/00 , C10G50/00 , C10G57/00 , C10G57/02 , Y02P20/52 , C07C11/04
摘要: The present disclosure provides natural gas and petrochemical processing systems including oxidative coupling of methane reactor systems that integrate process inputs and outputs to cooperatively utilize different inputs and outputs of the various systems in the production of higher hydrocarbons from natural gas and other hydrocarbon feedstocks.
摘要翻译: 本公开提供天然气和石油化学处理系统,包括甲烷反应器系统的氧化偶联,其将过程输入和输出相结合,以协调地利用各种系统在从天然气和其它烃原料生产高级烃的输入和输出。
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公开(公告)号:US06756355B1
公开(公告)日:2004-06-29
申请号:US08852666
申请日:1997-05-07
申请人: Kiran K. Chada , Hena Ashar , Alex Tkachenko , Xianjin Zhou
发明人: Kiran K. Chada , Hena Ashar , Alex Tkachenko , Xianjin Zhou
IPC分类号: A61K3800
CPC分类号: A61K38/1709 , A01K2217/05 , C07K14/4702 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/574 , G01N33/57484 , G01N2333/4703
摘要: The present invention relates to HMGI genes and proteins and methods of using the same. Embodiments of the invention pertain to methods for treating obesity, methods for treating a tumor, methods for producing a transgenic non-human mammal, methods for screening candidate compounds capable of inhibiting the biological activity of normal HMGI genes or proteins, and methods for detecting the presence of a tumor.
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公开(公告)号:US09718054B2
公开(公告)日:2017-08-01
申请号:US13115082
申请日:2011-05-24
申请人: Erik C. Scher , Fabio R. Zurcher , Joel M. Cizeron , Wayne P. Schammel , Alex Tkachenko , Joel Gamoras , Dmitry Karshtedt , Greg Nyce
发明人: Erik C. Scher , Fabio R. Zurcher , Joel M. Cizeron , Wayne P. Schammel , Alex Tkachenko , Joel Gamoras , Dmitry Karshtedt , Greg Nyce
IPC分类号: C07C2/82 , C07C2/84 , C07C2/76 , B01J23/10 , B01J21/06 , B01J23/34 , B01J23/22 , B01J35/06 , B01J21/10 , B01J35/00 , B01J37/00 , B01J37/03 , B01J37/08 , B01J37/10 , B82Y30/00 , C01F5/02 , C01F5/14 , C01F7/02 , C01F11/02 , C01F17/00 , C01G25/00 , C01G31/02 , C01G41/02 , C01G45/00 , C01G45/02 , C07C5/48 , C10G2/00 , C10G9/00 , B01J21/08 , B01J21/04 , B01J31/26
CPC分类号: B01J35/06 , B01J21/066 , B01J21/10 , B01J23/10 , B01J23/22 , B01J23/34 , B01J35/0013 , B01J37/0018 , B01J37/031 , B01J37/08 , B01J37/10 , B82Y30/00 , C01F5/02 , C01F5/14 , C01F7/02 , C01F11/02 , C01F17/0043 , C01G25/00 , C01G31/02 , C01G41/02 , C01G45/00 , C01G45/006 , C01G45/02 , C01P2002/52 , C01P2002/72 , C01P2004/04 , C01P2004/16 , C01P2004/54 , C01P2004/84 , C01P2006/12 , C07C2/84 , C07C5/48 , C07C2521/10 , C07C2523/02 , C07C2523/04 , C07C2523/10 , C07C2523/30 , C07C2523/34 , C07C2523/75 , C10G2/33 , C10G9/00 , C10G2300/1025 , C10G2300/70 , C10G2400/02 , C10G2400/20 , C10G2400/22 , Y02P20/52 , Y02P30/40 , C07C11/04 , C07C11/06
摘要: Methods for producing ethylene using nanowires as heterogeneous catalysts are provided. The method includes, for example, an oxidative coupling of methane catalyzed by nanowires to provide ethylene.
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公开(公告)号:US06720472B2
公开(公告)日:2004-04-13
申请号:US09226402
申请日:1999-01-06
申请人: Kiran K. Chada , Hena Ashar , Alex Tkachenko , Xianjin Zhou
发明人: Kiran K. Chada , Hena Ashar , Alex Tkachenko , Xianjin Zhou
IPC分类号: A01K6700
CPC分类号: C12Q1/6883 , A01K2217/05 , A61K38/1709 , C07K14/4702 , C12Q1/6886 , C12Q2600/136 , G01N33/574 , G01N33/57484 , G01N2333/4703
摘要: The present invention relates to HMGI genes and proteins and methods of using the same. Embodiments of the invention pertain to methods for treating obesity, methods for treating a tumor, methods for producing a transgenic non-human mammal, methods for screening candidate compounds capable of inhibiting the biological activity of normal HMGI genes or proteins, and methods for detecting the presence of a tumor.
摘要翻译: 本发明涉及HMGI基因和蛋白质及其使用方法。 本发明的实施方案涉及治疗肥胖症的方法,用于治疗肿瘤的方法,用于产生转基因非人哺乳动物的方法,用于筛选能够抑制正常HMGI基因或蛋白质的生物学活性的候选化合物的方法,以及用于检测 存在肿瘤。
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公开(公告)号:US20120041246A1
公开(公告)日:2012-02-16
申请号:US13115082
申请日:2011-05-24
申请人: Erik C. Scher , Fabio R. Zurcher , Joel M. Cizeron , Wayne P. Schammel , Alex Tkachenko , Joel Gamoras , Dmitry Karshtedt , Greg Nyce
发明人: Erik C. Scher , Fabio R. Zurcher , Joel M. Cizeron , Wayne P. Schammel , Alex Tkachenko , Joel Gamoras , Dmitry Karshtedt , Greg Nyce
IPC分类号: C07C2/76 , B01J23/10 , B01J21/06 , B01J23/34 , B01J21/08 , B01J23/22 , B01J21/04 , B01J31/26 , B01J31/38 , B01J31/34 , B01J31/32 , B01J31/36 , B01J21/12 , B01J21/10 , B82Y30/00 , B82Y40/00
CPC分类号: B01J35/06 , B01J21/066 , B01J21/10 , B01J23/10 , B01J23/22 , B01J23/34 , B01J35/0013 , B01J37/0018 , B01J37/031 , B01J37/08 , B01J37/10 , B82Y30/00 , C01F5/02 , C01F5/14 , C01F7/02 , C01F11/02 , C01F17/0043 , C01G25/00 , C01G31/02 , C01G41/02 , C01G45/00 , C01G45/006 , C01G45/02 , C01P2002/52 , C01P2002/72 , C01P2004/04 , C01P2004/16 , C01P2004/54 , C01P2004/84 , C01P2006/12 , C07C2/84 , C07C5/48 , C07C2521/10 , C07C2523/02 , C07C2523/04 , C07C2523/10 , C07C2523/30 , C07C2523/34 , C07C2523/75 , C10G2/33 , C10G9/00 , C10G2300/1025 , C10G2300/70 , C10G2400/02 , C10G2400/20 , C10G2400/22 , Y02P20/52 , Y02P30/40 , C07C11/04 , C07C11/06
摘要: Nanowires useful as heterogeneous catalysts are provided. The nanowire catalysts are useful in a variety of catalytic reactions, for example, the oxidative coupling of methane to ethylene. Related methods for use and manufacture of the same are also disclosed.
摘要翻译: 提供用作非均相催化剂的纳米线。 纳米线催化剂可用于各种催化反应,例如甲烷与乙烯的氧化偶联。 还公开了相关的使用和制造方法。
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公开(公告)号:US06171779B2
公开(公告)日:2001-01-09
申请号:US08679529
申请日:1996-07-12
申请人: Kiran K. Chada , Hena Ashar , Alex Tkachenko , Xianjin Zhou
发明人: Kiran K. Chada , Hena Ashar , Alex Tkachenko , Xianjin Zhou
IPC分类号: C12Q100
CPC分类号: A61K38/1709 , A01K2217/05 , C07K14/4702 , C12Q1/6883 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/574 , G01N33/57484 , G01N2333/4703
摘要: The present invention pertains to a method for detecting HMGI-C or HMGI(Y) as a diagnostic marker for benign or malignant tumors using a probe for a sample from a patient that recognizes HMGI-C or HMGI(Y). The method comprises the steps of (a) contacting HMGI-C or HMGI(Y) from a sample from a patient with a probe which binds to HMGI-C or HMGI(Y); and (b) analyzing for HMGI-C or HMGI(Y) by detecting levels of the probe bound to the HMGI-C or HMGI(Y). The presence of HMGI-C or HMGI(Y) in the sample is positive for a benign or malignant tumor. The present invention also pertains to a method for detecting antibodies to HMGI-C or HMGI(Y) as a diagnostic marker for benign or malignant tumors. The present invention further pertains to a method for treating benign and malignant tumors in a patient by blocking the biological activity of HMGI-C or HMGI(Y). The present invention also pertains to a method for treating obesity in a patient by blocking the biological activity of HMGI-C or HMGI(Y).
摘要翻译: 本发明涉及使用来自识别HMGI-C或HMGI(Y)的患者的样品的探针来检测HMGI-C或HMGI(Y)作为良性或恶性肿瘤的诊断标记物的方法。 该方法包括以下步骤:(a)将来自患者的样品的HMGI-C或HMGI(Y)与结合HMGI-C或HMGI(Y)的探针接触; 和(b)通过检测与HMGI-C或HMGI(Y)结合的探针的水平来分析HMGI-C或HMGI(Y)。 样品中HMGI-C或HMGI(Y)的存在对于良性或恶性肿瘤是阳性的。 本发明还涉及用于检测HMGI-C或HMGI(Y)的抗体作为良性或恶性肿瘤的诊断标记物的方法。 本发明还涉及通过阻断HMGI-C或HMGI(Y)的生物学活性来治疗患者的良性和恶性肿瘤的方法。 本发明还涉及通过阻断HMGI-C或HMGI(Y)的生物学活性来治疗患者肥胖的方法。
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