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    Measuring device and its use
    3.
    发明授权
    Measuring device and its use 有权
    测量装置及其用途

    公开(公告)号：US06198869B1

    公开(公告)日：2001-03-06

    申请号：US09308096

    申请日：1999-05-17

    申请人： Gerolf Kraus ,  Michael Pawlak ,  Gert Ludwig Duveneck ,  Peter Oroszlan ,  Andreas Helg ,  Alfredo Emilio Bruno-Raimondi

    发明人： Gerolf Kraus ,  Michael Pawlak ,  Gert Ludwig Duveneck ,  Peter Oroszlan ,  Andreas Helg ,  Alfredo Emilio Bruno-Raimondi

    IPC分类号： G01N2100

    CPC分类号： G01N21/648 ,  G01N21/05 ,  G01N21/7703 ,  G01N2021/0346

    摘要： A device comprising a planar optical waveguide, consisting of a transparent carrier (40) and a wave-guiding layer (41), wherein the waveguide at least has a diffractive element (42) for coupling excitation radiation into the wave-guiding layer, and there is located on the wave-guiding layer a further, tightly sealing layer (43) made from a material which, at least at the support surface, is transparent both to the excitation radiation and to the evanescently excited radiation at least to the penetration depth of the evanescent field, and which, for an analysis sample, has, at least in a partial region of the guided excitation radiation, a cavity (45) which is open to the upper side or a cavity (6) which is closed to the upper side and connected by means of an inflow channel (2) and an outflow channel (3), the depth of the cavity corresponding at least to the penetration depth of the evanescent field, and wherein the diffractive element (42) is fully covered by the material of the layer (43) at least in the coupling-in region of the excitation radiation.

    摘要翻译： 一种包括由透明载体（40）和波导层（41）组成的平面光波导的装置，其中所述波导至少具有用于将激发辐射耦合到波导层中的衍射元件（42），以及 位于波导层上的另一紧密密封层（43）由材料制成，所述材料至少在支撑表面上对于激发辐射和至少到穿透深度的消逝的辐射是透明的 ，并且对于分析样本，至少在被引导的激发辐射的部分区域中具有向上侧敞开的空腔（45）或与所述空腔（6）关闭的空腔（6），所述空腔 上侧并且通过流入通道（2）和流出通道（3）连接，所述空腔的深度至少对应于所述ev逝场的穿透深度，并且其中所述衍射元件（42）完全被 层的材料 （43）至少在激发辐射的耦合区域中。

    Measuring device and the use thereof
    5.
    发明授权
    Measuring device and the use thereof 有权

    公开(公告)号：US06384912B1

    公开(公告)日：2002-05-07

    申请号：US09742391

    申请日：2000-12-22

    申请人： Gerolf Kraus ,  Michael Pawlak ,  Gert Ludwig Duveneck ,  Peter Oroszlan ,  Andreas Helg ,  Alfredo Emilio Bruno-Raimondi

    发明人： Gerolf Kraus ,  Michael Pawlak ,  Gert Ludwig Duveneck ,  Peter Oroszlan ,  Andreas Helg ,  Alfredo Emilio Bruno-Raimondi

    IPC分类号： G01N110

    摘要： A device has a planar optical waveguide, including a transparent carrier (40) and a wave-guiding layer (41), wherein the waveguide at least has a diffractive element (42) for coupling excitation radiation into the wave-guiding layer. Located on the wave-guiding layer is a further, tightly sealing layer (43) made from a material which, at least at the support surface, is transparent both to the excitation radiation and to the evanescently excited radiation at least to the penetration depth of the evanescent field, and which, for an analysis sample, has, at least in a partial region of the guided excitation radiation, a cavity (45) which is open to the upper side or a cavity (6) which is closed to the upper side and connected by means of an inlet channel (2) and an outlet channel (3). The depth of the cavity corresponds at least to the penetration depth of the evanescent field, and the diffractive element (42) is fully covered by the material of the layer (43) at least in the coupling-in region of the excitation radiation.

    Optical detection apparatus for chemical analyses of small volumes of samples
    7.
    发明授权
    Optical detection apparatus for chemical analyses of small volumes of samples 有权
    用于小批量样品化学分析的光学检测装置

    公开(公告)号：US6084683A

    公开(公告)日：2000-07-04

    申请号：US194523

    申请日：1998-11-25

    申请人： Alfredo Emilio Bruno ,  Steven Mark Barnard ,  Markus Ehrat ,  Reinhard Volkel ,  Philippe Nussbaum ,  Hans Peter Herzig

    发明人： Alfredo Emilio Bruno ,  Steven Mark Barnard ,  Markus Ehrat ,  Reinhard Volkel ,  Philippe Nussbaum ,  Hans Peter Herzig

    IPC分类号： G01N21/64 ,  G01N21/03

    CPC分类号： G01N21/03 ,  G01N2021/0346

    摘要： Optical detection apparatus for chemical analyses of small volumes of samples has light sources (21) to emit induction light, a measuring cell (7) for the sample, photoelectric sensing elements (22) to receive light coming form the sample in the measuring cell (7), as well as beam-conducting means for the induction light or the light from the sample. In the apparatus, several essentially planar, laminar components (2-7) are arranged in a sandwich structure, whereby the components (2-7) contain the light sources (21), the measuring cell (7), the photoelectric sensing elements (22), and also the beam conducting means.

    摘要翻译： PCT No.PCT / EP97 / 02745 Sec。 371日期：1998年11月25日 102（e）1998年11月25日日期PCT提交1997年5月27日PCT公布。 WO97 / 45718 PCT公开号 日期1997年12月4日用于小体积样品的化学分析的光学检测装置具有发射感光的光源（21），用于样品的测量单元（7），用于接收来自样品的光的光电感测元件（22） 在测量单元（7）中，以及用于感应光或来自样品的光的光束传导装置。 在该设备中，几个基本上平面的层状部件（2-7）被布置成夹层结构，由此部件（2-7）包含光源（21），测量单元（7），光电感测元件 22），以及光束传导装置。

    Optical detection device for analytical measurement of chemical substances
    8.
    发明授权
    Optical detection device for analytical measurement of chemical substances 失效
    用于化学物质分析测量的光学检测装置

    公开(公告)号：US5757014A

    公开(公告)日：1998-05-26

    申请号：US625330

    申请日：1996-04-01

    申请人： Alfredo Emilio Bruno ,  Steven Mark Barnard ,  Marizel Rouilly

    发明人： Alfredo Emilio Bruno ,  Steven Mark Barnard ,  Marizel Rouilly

    IPC分类号： G01N21/01 ,  G01N21/64 ,  G01N21/77

    CPC分类号： G01N21/7703 ,  G01N21/645

    摘要： In the optical detection device (1), the excitation light guide (11) and the emission light guide (12) form a structural unit having the end face (14) facing the fluorescence changer (4). The end face (14) physically corresponds substantially to one of the boundary surfaces of the two light guides (11, 12). As a result, the detection device (1) can be separated in a simple manner into an optical part and a mechanical part which are in optical contact only by way of the end face (14). All of the elements in the optical light path are connected in a mechanically stable manner by means of the index-matching medium 20, as a result of which the light between the light source (10) and the photoelectric sensor (13) propagates only in media having a comparable refractive index. The light source (10) is preferably a light-emitting diode. A plurality of those detection devices can be combined to form a compact detection apparatus with which the substance (3) can be examined with regard to several constituents in one measuring operation.

    摘要翻译： 在光检测装置（1）中，激发光导（11）和发射光导（12）形成具有面向荧光变换器（4）的端面（14）的结构单元。 端面（14）物理地基本上对应于两个光导（11,12）的边界表面之一。 结果，可以将检测装置（1）以简单的方式分离成仅通过端面（14）光学接触的光学部件和机械部件。 光学路径中的所有元件通过折射率匹配介质20以机械稳定的方式连接，结果，光源（10）和光电传感器（13）之间的光仅在 具有相当折射率的介质。 光源（10）优选为发光二极管。 可以将多个检测装置组合以形成紧凑的检测装置，在一次测量操作中可以通过该检测装置检查物质（3）关于若干成分。