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公开(公告)号：US20130168470A1
公开(公告)日：2013-07-04
申请号：US13495940
申请日：2012-06-13
CPC分类号： F23D14/46 , B21D53/00 , F23D1/00 , F23D14/76 , F23D2201/10 , F23D2201/20 , F23D2201/30 , F23D2900/00018 , Y10T29/49348
摘要： A burner tip, and method of manufacture, has a support layer with an external surface exposed to combustion reactions and an unexposed internal surface defining at least one a passage therethrough to deliver fuel and combustion gasses, and a thermal protective layer disposed on at least part of the unexposed surface of the burner tip support layer. The thermal protective layer 22 has from about 5% to about 40% of an inorganic adhesive, from about 45% to about 92% of a filler, and from about 1% to about 20% of one or more emissivity agents.
摘要翻译： 燃烧器尖端和制造方法具有支撑层，其具有暴露于燃烧反应的外部表面和未暴露的内表面，其限定穿过其中的至少一个通道以输送燃料和燃烧气体，以及设置在至少部分上的热保护层 的燃烧器尖端支撑层的未曝光表面。 热保护层22具有约5％至约40％的无机粘合剂，约45％至约92％的填料和约1％至约20％的一种或多种发射剂。
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公开(公告)号：US08011190B2
公开(公告)日：2011-09-06
申请号：US12224198
申请日：2007-02-21
IPC分类号： F25D3/00
CPC分类号： B67D1/0867 , B67D1/0054 , B67D1/0857 , F25C2301/002 , F25D17/02 , F25D31/002
摘要： A cooling system for beverage dispense has a circuit 5 in which binary ice is circulated. A modular heat exchange unit 13 for a plurality of beverage lines 25,27,29,31,33 is connected to the circuit 5 for cooling beverage prior to dispense from a dispense tap 35 in a serving area such as a bar. The ice fraction in the binary ice provides a thermal store that can absorb heat without increasing the temperature of the binary ice and enables the system to respond quickly to changes in the cooling requirements in the circuit 5.
摘要翻译： 用于饮料分配的冷却系统具有二元冰循环的回路5。 用于多个饮料管线25,27,29,31,33的模块化热交换单元13连接到用于冷却饮料的回路5，然后从诸如酒吧的服务区域中的分配抽头35分配。 二进制冰中的冰分数提供了一个热存储器，可以吸收热量，而不会增加二元冰的温度，并使系统能够快速响应电路5中冷却要求的变化。
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公开(公告)号：US07919079B2
公开(公告)日：2011-04-05
申请号：US11729339
申请日：2007-03-28
申请人： Andrew Simmons , Karin Jooss , James Allison
发明人： Andrew Simmons , Karin Jooss , James Allison
IPC分类号： A01N63/00
CPC分类号： A61K39/0011 , A61K39/0008 , A61K39/39 , A61K39/39558 , A61K2039/505 , A61K2039/5152 , A61K2039/55516 , A61K2039/55522 , C07K16/2818
摘要： Cellular compositions and methods for inducing an immune response to tumor cells are described. The cellular compositions include a tumor antigen and cells that have been modified to express a cytokine and one or more of a tumor antigen, anti-CTLA4 antibody and an additional cytokine. The cellular compositions find utility in methods for treating cancer.
摘要翻译： 描述了诱导对肿瘤细胞的免疫应答的细胞组合物和方法。 细胞组合物包括肿瘤抗原和已被修饰以表达细胞因子和肿瘤抗原，抗CTLA4抗体和另外的细胞因子中的一种或多种的细胞。 细胞组合物可用于治疗癌症的方法。
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公开(公告)号：US07709224B2
公开(公告)日：2010-05-04
申请号：US10831304
申请日：2004-04-26
申请人： Jianmin Fang , Karin Jooss , Andrew Simmons , Jing-Jing Qian
发明人： Jianmin Fang , Karin Jooss , Andrew Simmons , Jing-Jing Qian
CPC分类号： C12N15/86 , C07K16/00 , C07K16/2863 , C07K2317/21 , C07K2317/76 , C07K2319/30 , C07K2319/50 , C12N15/8273 , C12N2750/14143 , C12N2800/60 , C12N2830/00 , C12N2830/15 , C12N2830/42 , C12N2830/48 , C12N2830/85 , C12N2830/90 , C12N2840/203
摘要： Vector constructs for expression of two or more functional proteins or polypeptides under operative control of a single promoter and methods of making and using the same are described. The vectors comprise a self-processing cleavage site between each respective protein or polypeptide coding sequence. The vector constructs include the coding sequence for a self-processing cleavage site and may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from expressed protein(s) or polypeptide(s). The vector constructs find utility in methods for enhanced production of biologically active proteins and polypeptides in vitro and in vivo.
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公开(公告)号：US20100038061A1
公开(公告)日：2010-02-18
申请号：US12192721
申请日：2008-08-15
CPC分类号： F28F19/002 , F22B37/107 , Y10T29/4935
摘要： A tube shield, and method of manufacturing the tube shield, having a support structure with an external surface, an internal surface, and an edge, and a thermal protective layer on at least one surface of the shield support structure. The thermal protective layer is composed of a filler, one or more emissivity agent, and either an inorganic adhesive or a binder that is colloidal silica, colloidal alumina, or combinations thereof. A colorant, a surfactant, and/or a stabilizer may be incorporated into the thermal protective layer.
摘要翻译： 管屏蔽，以及制造管屏蔽的方法，其具有在屏蔽支撑结构的至少一个表面上具有外表面，内表面和边缘的支撑结构以及热保护层。 热保护层由填料，一种或多种发射剂，以及无机粘合剂或胶体二氧化硅，胶态氧化铝或其组合的粘合剂组成。 着色剂，表面活性剂和/或稳定剂可以并入热保护层中。
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公开(公告)号：US20080014222A1
公开(公告)日：2008-01-17
申请号：US11729339
申请日：2007-03-28
申请人： Andrew Simmons , Karin Jooss , James Allison
发明人： Andrew Simmons , Karin Jooss , James Allison
CPC分类号： A61K39/0011 , A61K39/0008 , A61K39/39 , A61K39/39558 , A61K2039/505 , A61K2039/5152 , A61K2039/55516 , A61K2039/55522 , C07K16/2818
摘要： Cellular compositions and methods for inducing an immune response to tumor cells are described. The cellular compositions include a tumor antigen and cells that have been modified to express a cytokine and one or more of a tumor antigen, anti-CTLA4 antibody and an additional cytokine. The cellular compositions find utility in methods for treating cancer.
摘要翻译： 描述了诱导对肿瘤细胞的免疫应答的细胞组合物和方法。 细胞组合物包括肿瘤抗原和已被修饰以表达细胞因子和肿瘤抗原，抗CTLA4抗体和另外的细胞因子中的一种或多种的细胞。 细胞组合物可用于治疗癌症的方法。
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公开(公告)号：US06705489B2
公开(公告)日：2004-03-16
申请号：US10154381
申请日：2002-05-22
申请人： Paul Henry , Steve Czeck , Philip Andrew Simmons , Keith James Heyes , Martin Johnson , Jamie Atkinson
发明人： Paul Henry , Steve Czeck , Philip Andrew Simmons , Keith James Heyes , Martin Johnson , Jamie Atkinson
IPC分类号： B67D556
CPC分类号： B67D1/1234 , B67D1/005 , B67D1/0085 , B67D1/1218 , B67D1/1295 , B67D2001/0088
摘要： The present invention comprises a valve providing for the dispensing of two liquids at a desired ratio. The valve includes first and second liquid flow body assemblies releasably securable to a nozzle body assembly. Each liquid flow body assembly is securable to a source of liquid and includes flow sensing means and flow regulating means. A control receives inputs from the flow sensing means and regulates the operation of the flow regulating means to provide for the dispensing of the two liquids from the nozzle body assembly at a predetermined ratio.
摘要翻译： 本发明包括一个提供以期望的比例分配两种液体的阀。 阀包括可释放地固定到喷嘴主体组件的第一和第二液体流动体组件。 每个液体流动体组件可固定到液体源，并且包括流量检测装置和流量调节装置。 控制器接收来自流量检测装置的输入，并且调节流量调节装置的操作以提供以预定比例从喷嘴主体组件分配两种液体。
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公开(公告)号：US06474504B1
公开(公告)日：2002-11-05
申请号：US09937369
申请日：2001-09-21
IPC分类号： B67D516
CPC分类号： B67D1/14
摘要： The present invention is a flow rate control valve through which a liquid flows and from which the liquid is dispensed. The flow rate of the liquid is sensed and that information is sent to a microprocessor based control. The control operates a drive of the control valve so as to vary the resultant rate at which the liquid is dispensed therefrom. The drive operates a piston closure member that extends closely within a cylindrical passageway. The passageway has an inlet end and an outlet end and the drive operates the closure member in the passageway to a plurality of positions from a first position at the inlet end and a second position at the outlet end. The wall of the passageway defines at least one groove having a transverse cross-section that increases in area in a downstream direction from the passageway inlet to the passageway outlet or in an upstream direction from the passageway outlet to the passageway inlet, whereby movement of the closure between the first position and the second position varies the flow rate of the liquid through the control valve as a function of the cross-sectional area of the groove.
摘要翻译： 本发明是一种流量控制阀，通过该流量控制阀流出液体并从中分配液体。 检测液体的流速，并将该信息发送到基于微处理器的控制。 控制器操作控制阀的驱动，以便改变从其分配液体的合成速率。 驱动器操作在圆柱形通道内紧密延伸的活塞关闭件。 通道具有入口端和出口端，并且驱动器将通道中的关闭构件从入口端处的第一位置和出口端处的第二位置操作到多个位置。 通道的壁限定至少一个具有横向横截面的凹槽，该横截面在从通道入口到通道出口的下游方向上的面积增加，或者在从通道出口到通道入口的上游方向上增加， 在第一位置和第二位置之间的关闭根据槽的横截面积改变通过控制阀的液体的流速。
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公开(公告)号：USRE43334E1
公开(公告)日：2012-05-01
申请号：US11274720
申请日：2005-11-15
CPC分类号： B67D1/0032
摘要： Apparatus for mixing two fluids has separate supply lines for delivering the fluids to a mixing head. Flow rate of fluid in one supply line is monitored by arranging a pressure transducer to measure a pressure drop across an orifice in an orifice plate arranged in the supply line and a controller is responsive to the detected flow rate to control flow rate of fluid in the other supply line to achieve a desired flow ratio of both fluids at the mixing head for producing a mixed fluid having the correct proportions of both fluids. The fluids may be a concentrate syrup and a plain or carbonated water to produce a beverage.
摘要翻译： 用于混合两种流体的装置具有用于将流体输送到混合头的单独的供应管线。 通过布置压力传感器来测量一个供应管线中的流体的流速，以测量布置在供应管线中的孔板中的孔口上的压降，并且控制器响应于检测到的流速来控制流体的流速 其他供应管线以实现混合头处两种流体的期望流量比，用于生产具有两种流体的正确比例的混合流体。 流体可以是浓缩糖浆和平原或碳酸水以产生饮料。
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公开(公告)号：US20100041927A1
公开(公告)日：2010-02-18
申请号：US12190227
申请日：2008-08-12
IPC分类号： C07C17/357 , B01J19/00
CPC分类号： C07C21/06 , B01J19/02 , B01J19/2425 , B01J2219/00157 , B01J2219/0263 , B01J2219/0286 , C07C17/02 , C07C17/156 , C07C17/25 , C07C19/045
摘要： Process and apparatus to form vinyl chloride monomer from ethylene dichloride in a cracking furnace, including a firebox chamber having a thermal protective layer disposed on refractory walls and/or process tubes disposed within the chamber, a quencher to form vinyl chloride monomer, and fractionator separate products. The thermal protective layer which contains an inorganic adhesive for metal/alloy tubes or colloidal silica and/or colloidal alumina for refractory walls or ceramic tubes, a filler, and one or more emissivity agents.
摘要翻译： 在裂解炉中由二氯乙烯形成氯乙烯单体的方法和装置，包括具有设置在室内的耐热壁和/或处理管上的热保护层的火炉室，形成氯乙烯单体的猝灭剂和分离器 产品。 包含用于金属/合金管的无机粘合剂或用于耐火壁或陶瓷管的胶体二氧化硅和/或胶体氧化铝的热保护层，填料和一种或多种发射剂。
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