-
公开(公告)号：US06051552A
公开(公告)日：2000-04-18
申请号：US867002
申请日：1997-05-30
CPC分类号： C12P1/04 , A61K35/747 , Y10S435/803 , Y10S435/82 , Y10S435/853 , Y10S435/854 , Y10S435/855 , Y10S435/856 , Y10S435/857
摘要： The present invention is directed towards isolated lactobacillus biosurfactants and the process for producing same. The present invention is also directed to methods for preventing urogenital infection in mammals using the isolated lactobacillus biosurfactant. The present invention is further directed to methods of inhibiting microbial biofilm formation using the isolated lactobacillus biosurfactant to prevent the formation of bacterial biofilms, and to displace adherent biofilm-forming bacteria from surfaces.
摘要翻译： 本发明涉及分离的乳酸杆菌生物表面活性剂及其制备方法。 本发明还涉及使用分离的乳酸杆菌生物表面活性剂来预防哺乳动物的泌尿生殖器感染的方法。 本发明还涉及使用分离的乳杆菌生物表面活性剂抑制微生物生物膜形成的方法，以防止细菌生物膜的形成，并从表面置换粘附的生物膜形成细菌。
-
2.发明授权
公开(公告)号：US5804179A
公开(公告)日：1998-09-08
申请号：US315665
申请日：1994-09-30
申请人： Andrew W. Bruce , Gregor Reid
发明人： Andrew W. Bruce , Gregor Reid
IPC分类号： A61K35/74 , A61K35/747 , C12N1/20
CPC分类号： A61K35/747 , Y10S435/853 , Y10S435/854 , Y10S435/855 , Y10S435/856 , Y10S435/857
摘要： This invention relates to lactobacillus compositions and methods of employing said compositions for treating or preventing urinary tract infections. More particularly, this invention relates to the ability of certain strains of lactobacilli to adhere to uroepithelial or vaginal epithelial cells and to exhibit inhibitory activity against the growth of pathogenic bacteria.
摘要翻译： 本发明涉及乳酸杆菌组合物和使用所述组合物治疗或预防尿路感染的方法。 更具体地，本发明涉及某些乳酸杆菌菌株粘附于上皮细胞或阴道上皮细胞并且表现出对致病细菌生长的抑制活性的能力。
-
3.发明授权公开(公告)号：US06180100B2
公开(公告)日：2001-01-30
申请号：US09112732
申请日：1998-07-09
申请人： Andrew W. Bruce , Gregor Reid
发明人： Andrew W. Bruce , Gregor Reid
IPC分类号： C12N120
CPC分类号： A61K35/747
摘要： This invention relates to lactobacillus compositions and methods of employing said compositions for treating or preventing urinary tract infections. More particularly, this invention relates to the ability of certain strains of lactobacilli to adhere to uroepithelial or vaginal epithelial cells and to exhibit inhibitory activity against the growth of pathogenic bacteria.
摘要翻译： 本发明涉及乳酸杆菌组合物和使用所述组合物治疗或预防尿路感染的方法。 更具体地，本发明涉及某些乳酸杆菌菌株粘附于上皮细胞或阴道上皮细胞并且表现出对致病细菌生长的抑制活性的能力。
-
4.发明授权Lactobacillus and skim milk compositions and methods for preventing microbial urogenital infections 失效乳杆菌和脱脂乳组合物和预防微生物泌尿生殖器感染的方法
公开(公告)号：US5645830A
公开(公告)日：1997-07-08
申请号：US244096
申请日：1994-09-19
申请人： Gregor Reid , Andrew W. Bruce
发明人： Gregor Reid , Andrew W. Bruce
CPC分类号： A61K35/20 , A61K35/747 , A61K9/0034 , Y10S435/853 , Y10S435/854 , Y10S435/855 , Y10S435/856 , Y10S435/857 , Y10S514/968
摘要： This invention relates to Lactobacillus, skim milk, Lactobacillus Growth Factor (LGF) and Lactobacillus compositions and methods of employing the compositions for preventing urogenital infections. More particularly, this invention relates to the ability of strains of hydrophobic or hydrophilic Lactobacillus to adhere to biomaterials, and intestinal, vaginal and uroepithelial cells, to resist the action of certain antimicrobial agents and to dominate the urogenital flora.
摘要翻译： PCT No.PCT / CA92 / 00491 Sec。 371日期1994年9月19日 102（e）日期1994年9月19日PCT提交1992年11月13日PCT公布。 出版物WO93 / 09793 日期1993年5月27日本发明涉及乳酸杆菌，脱脂乳，乳杆菌生长因子（LGF）和乳杆菌组合物以及使用该组合物预防泌尿生殖器感染的方法。 更具体地说，本发明涉及疏水或亲水的乳杆菌菌株粘附于生物材料以及肠，阴道和尿路上皮细胞以抵抗某些抗微生物剂的作用并支配泌尿生殖菌群的能力。
-
公开(公告)号：US06613549B2
公开(公告)日：2003-09-02
申请号：US09780841
申请日：2001-02-09
申请人： Gregor Reid , Andrew W. Bruce , Victor Han
发明人： Gregor Reid , Andrew W. Bruce , Victor Han
IPC分类号： C12N120
CPC分类号： A61K35/745 , A61K35/747 , Y02A50/475 , Y02A50/481
摘要： The invention relates to probiotic microbes, including but not limited to Lactobacillus species and Bifidobacteria species, and their compositions and methods of employing said compositions for treating and preventing intestinal and other infections which originate from the intestine, in newborn infants. The invention also invention relates to the ability of probiotic organisms, either in viable or nonviable state, or their by-products, to interfere with pathogenic infection through short and long term colonization of the intestine, inhibition of growth of the pathogens, and assisting the host to fight off the infecting organisms.
摘要翻译： 本发明涉及益生菌微生物，包括但不限于乳杆菌属物种和双歧杆菌物种，以及它们在新生儿中使用所述组合物用于治疗和预防源于肠道的肠道和其它感染的组合物和方法。 本发明还涉及益生菌生物在活的或不可行的状态或其副产物中通过短期和长期肠道定殖干扰病原体感染的能力，抑制病原体的生长，以及协助 主持人打击感染生物。
-
公开(公告)号：US6004551A
公开(公告)日：1999-12-21
申请号：US753557
申请日：1996-11-26
申请人： Gregor Reid , Andrew W. Bruce
发明人： Gregor Reid , Andrew W. Bruce
CPC分类号： A61K35/20 , A61K35/747 , A61K9/0034 , Y10S435/853 , Y10S435/854 , Y10S435/855 , Y10S435/856 , Y10S435/857 , Y10S514/968
摘要： This invention relates to lactobacillus, skim milk, lactobacillus growth factor (LGF) and lactobacillus compositions and methods of employing said composition for preventing urogenital infections. More particularly, this invention relates to the ability of strains of hydrophobic or hydrophilic lactobacillus to adhere to biomaterials, intestinal, vaginal and uroepithelial cells, to resist the action of certain anti-microbial agents and to dominate the urogenital flora.
摘要翻译： 本发明涉及乳杆菌，脱脂乳，乳杆菌生长因子（LGF）和乳杆菌组合物以及采用所述组合物预防泌尿生殖器感染的方法。 更具体地说，本发明涉及疏水或亲水乳杆菌菌株粘附于生物材料，肠道，阴道和尿路上皮细胞上的能力，以抵抗某些抗微生物剂的作用并支配泌尿生殖菌群。
-
7.发明授权公开(公告)号：US06479051B1
公开(公告)日：2002-11-12
申请号：US09459292
申请日：1999-12-10
申请人： Andrew W. Bruce , Gregor Reid
发明人： Andrew W. Bruce , Gregor Reid
IPC分类号： C12N120
CPC分类号： A61K35/745 , A61K35/747 , C12Q1/689 , A61K2300/00
摘要： The present invention provides methods and compositions for the oral administration of Lactobacillus and/or other probiotic organisms, such as Bifidobacterium, for establishment and maintenance of a healthy urogenital flora. The invention also provides methods and compositions to reduce the risk of disease.
摘要翻译： 本发明提供用于口服施用乳酸杆菌和/或其他益生菌生物体如双歧杆菌的方法和组合物，用于建立和维持健康的泌尿生殖菌群。 本发明还提供降低疾病风险的方法和组合物。
-
公开(公告)号：US5705160A
公开(公告)日：1998-01-06
申请号：US467354
申请日：1995-06-06
申请人： Andrew W. Bruce , Gregor Reid
发明人： Andrew W. Bruce , Gregor Reid
IPC分类号： A61K35/74 , A61K35/747
CPC分类号： A61K35/747 , Y10S435/853 , Y10S435/854 , Y10S435/855 , Y10S435/856 , Y10S435/857
摘要： This invention relates to lactobacillus compositions and methods of employing said compositions for treating or preventing urinary tract infections. More particularly, this invention relates to the ability of certain strains of lactobacilli to adhere to uroepithelial or vaginal epithelial cells and to exhibit inhibitory activity against the growth of pathogenic bacteria.
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.016 秒)
