摘要:
Flavonoid compounds may be prepared that are selective for certain cell organelles, and may be used as biological imaging agents. Organelles that may be imaged with flavonoid compounds include mitochondria and lysosomes. Advantageously, the flavonoids show specificity to certain organelles and may exhibit a florescence “turn-on” mechanism, where the flavonoids that have target an organelle exhibit a florescence response when excited.
摘要:
The present disclosure is generally related to antibodies that bind specifically to glioblastoma multiforme (GBM) cells. In particular, the present disclosure provides compositions comprising human single chain or full-length antibodies that bind tumor cells. Additionally the present disclosure provides methods of using the anti-GBM antibodies.
摘要:
A power saving method and a power saving system are applied in an optical disk drive. The power saving system comprises a power controlling unit for differentiating the specific sets of circuits not being used at a specific operation rate and powering them down. The sets of circuits not being used will be powered up while the associated operation rate at which they are required to operate is nearly started.
摘要:
A recirculation fan includes a casing, a covering member, and a fan assembly. The casing has a base. The covering member is coupled with the casing to define an accommodation space. The fan assembly is disposed within the accommodation space, and includes a first impeller, a second impeller, a motor, and a plurality of magnetic elements. The second impeller is located beside the first impeller. The motor is fixed on the base of the casing and connected with the first impeller for driving rotation of the first impeller. The magnetic elements are arranged between the first impeller and the second impeller. A wind force generated by the first impeller and a magnetic torque resulted from a magnetic vortex of the magnetic elements cause contactless rotation of the second impeller.
摘要:
The development of fluorescent bioprobes comprising organic fluorescent compounds that exhibit aggregation induced emission (AIE) properties, methods of producing the same, and their practical applications for in vitro and in vivo bioimaging.
摘要:
A fluorine-containing anti-corrosive coating is prepared by using fluororubber as basic film-forming substance, adding auxiliary agent, reinforcing agent and additive, kneading to obtain fluorine mixed compound, dissolving in organic solvent to obtain component A solution of the mixed compound; and while using it, mixing the component A solution with silane coupling agent as component B at a certain proportion, curing at low temperature and obtaining the fluorine-containing coating.
摘要:
Systems, methods, and apparatus are provided for vulnerability signature based Network Intrusion Detection and/or Prevention which achieves high throughput comparable to that of the state-of-the-art regex-based systems while offering improved accuracy. A candidate selection algorithm efficiently matches thousands of vulnerability signatures simultaneously using a small amount of memory. A parsing transition state machine achieves fast protocol parsing. Certain examples provide a computer-implemented method for network intrusion detection. The method includes capturing a data message and invoking a protocol parser to parse the data message. The method also includes matching the parsed data message against a plurality of vulnerability signatures in parallel using a candidate selection algorithm and detecting an unwanted network intrusion based on an outcome of the matching.
摘要:
The present invention generally relates to water-soluble, highly fluorescent polyhedral oligomeric silsesquioxane (POSS) compounds useful for sensing and bioimaging applications.
摘要:
Systems and methods for enhancing spectral domain optical coherence tomography (OCT] are provided. In particular, a system and method for calibration of spectral interference signals using an acquired calibration signal are provided. The calibration signal may be logarithmically amplified to further improve the accuracy of the calibration. From the calibration signal, a series of more accurate calibration data are calculated. An acquired spectral interference signal is calibrated using these calibration data. Moreover, systems that include logarithmic amplification of the spectral interference signal and variable band-pass filtering of the spectral interference signal are provided. Such systems increase the dynamic range and visualization capabilities relative to conventional spectral domain OCT systems.
摘要:
The present invention relates to conjugated polyelectrolyte (CPE) or oligoelectrolyte (COE) compounds represented by general structural formulae (I)-(IV), or a salt thereof and methods of using these compounds to detect targets in samples. In particular, the methods include: (1) exposing a sample to a compound of structural formula (I), (II) or (IV) or a salt thereof, allowing the compound to bind to a target and detecting a signal produced by the compound; (2) functionalizing a solid support with a ligand, incubating the sample with a charged CPE or COE and detecting the fluorescence of the solid support and thereby detecting the target or (3) functionalizing a surface of a solid support with a charged ligand, thereby creating a charge on the surface of the solid support; incubating the ligand-functionalized solid support with a sample, whereupon binding of the target, the charge on the surface of the solid support switches; incubating the sample with CPE or COE that has a complementary charge to the charge of the target-bound surface; and detecting the fluorescence of the solid support and thereby detecting the target. The compounds of the present invention possess high photoluminescence quantum yields in biological media, low cytotoxicity, and excellent environmental stability and photostability and can be used in biosensor and bioimaging applications.