-
公开(公告)号：US20210378814A1
公开(公告)日：2021-12-09
申请号：US17412124
申请日：2021-08-25
发明人： Tae Hyun Choi , Yan Lee , Ji Ung Park , Ji Yeon Ham , Hee Jin Kim , Suk Wha Kim , Hye Jeong Min
摘要： The present invention relates to a coating composition for an in-vivo implantable prosthesis including a photoinitiator, a crosslinking agent, and a phosphorylcholine (pc) monomer having an acrylate group, a method of coating an in-vivo implantable prosthesis using the coating composition, and a cosmetic prosthesis coated with the crosslinked polyphosphorylcholine.
An in-vivo implantable prosthesis coated with crosslinked polyphosphorylcholine may be manufactured by a simple method of applying a coating composition including a photoinitiator, a crosslinking agent, and a phosphorylcholine (pc) monomer having an acrylate group according to the present invention, and then irradiating uv rays. The crosslinked polyphosphorylcholine coating may provide hydrophilicity for the surface and may also remarkably reduce adsorption of proteins and fibroblasts, which may cause side effects such as capsular contracture. Further, the coating has strong enough not to peel off even under stimulation, and therefore, it is maintained under vigorous activity after implantation, thereby being usefully applied to the manufacture of an in-vivo implantable prosthesis with reduced side effects, such as breast prosthesis for cosmetic surgery.-
公开(公告)号：US20220218872A1
公开(公告)日：2022-07-14
申请号：US17610418
申请日：2020-05-07
发明人： Yan Lee , Sun Ah Kang , Tae Hyun Choi , Ji Ung Park , Seul Ah Kim , Jung Ah Kim , Mi Ok Kim , Young Min Kim , Xian Jin , Wufuer Maierdanjiang , Gee Ho Park , Byoung Jun Jeon , Eun Jung Choi , Yan Huang
摘要： Provided is a method for coating an implant using heat, and more particularly to a method for coating only the surface of an implant with a biocompatible polymer by using heat while maintaining physical characteristics of the implant.
The method for coating an implant using heat according to the present invention may effectively introduce a biocompatible polymer onto a three-dimensional material surface and thus may overcome the spatial limitations of light, and enables mass-coating and thus may be effectively used in the manufacture of an implant coated with a biocompatible polymer.-
公开(公告)号：US11925547B2
公开(公告)日：2024-03-12
申请号：US17412124
申请日：2021-08-25
发明人： Tae Hyun Choi , Yan Lee , Ji Ung Park , Ji Yeon Ham , Hee Jin Kim , Suk Wha Kim , Hye Jeong Min
CPC分类号： A61F2/12 , A61F2/0059 , A61F2/0063 , A61L27/28 , A61L27/32 , A61L27/34 , B05D1/02 , A61F2002/0086 , A61F2002/009 , A61L2300/216 , A61L2400/18 , A61L2430/04 , C08F2/48
摘要： The present invention relates to a coating composition for an in-vivo implantable prosthesis including a photoinitiator, a crosslinking agent, and a phosphorylcholine (pc) monomer having an acrylate group, a method of coating an in-vivo implantable prosthesis using the coating composition, and a cosmetic prosthesis coated with the crosslinked polyphosphorylcholine.
An in-vivo implantable prosthesis coated with crosslinked polyphosphorylcholine may be manufactured by a simple method of applying a coating composition including a photoinitiator, a crosslinking agent, and a phosphorylcholine (pc) monomer having an acrylate group according to the present invention, and then irradiating uv rays. The crosslinked polyphosphorylcholine coating may provide hydrophilicity for the surface and may also remarkably reduce adsorption of proteins and fibroblasts, which may cause side effects such as capsular contracture. Further, the coating has strong enough not to peel off even under stimulation, and therefore, it is maintained under vigorous activity after implantation, thereby being usefully applied to the manufacture of an in-vivo implantable prosthesis with reduced side effects, such as breast prosthesis for cosmetic surgery.-
公开(公告)号：US11129706B2
公开(公告)日：2021-09-28
申请号：US15304780
申请日：2015-04-17
发明人： Tae Hyun Choi , Yan Lee , Ji Ung Park , Ji Yeon Ham , Hee Jin Kim , Suk Wha Kim , Hye Jeong Min
摘要： The present invention relates to a coating composition for an in-vivo implantable prosthesis including a photoinitiator, a crosslinking agent, and a phosphorylcholine (PC) monomer having an acrylate group, a method of coating an in-vivo implantable prosthesis using the coating composition, and a cosmetic prosthesis coated with the crosslinked polyphosphorylcholine.
An in-vivo implantable prosthesis coated with crosslinked polyphosphoryicholine may be manufactured by a simple method of applying a coating composition including a photoinitiator, a crosslinking agent, and a phosphorylcholine (PC) monomer having an acrylate group according to the present invention, and then irradiating UV rays. The crosslinked polyphosphorylcholine coating may provide hydrophilicity for the surface and may also remarkably reduce adsorption of proteins and fibroblasts, which may cause side effects such as capsular contracture. Further, the coating has strong enough not to peel off even under stimulation, and therefore, it is maintained under vigorous activity after implantation, thereby being usefully applied to the manufacture of an in-vivo implantable prosthesis with reduced side effects, such as breast prosthesis for cosmetic surgery.
-
-
-
搜索结果
4 条记录 (耗时 0.011 秒)
