公开(公告)号：US09088826B2

公开(公告)日：2015-07-21

申请号：US11492281

申请日：2006-07-24

申请人： James M. Barton ,  Paul Stevens ,  David Sandford ,  Robin Hayes ,  Margret Schmidt ,  Bruce Klein

发明人： James M. Barton ,  Paul Stevens ,  David Sandford ,  Robin Hayes ,  Margret Schmidt ,  Bruce Klein

IPC分类号： H04N21/472 ,  G06Q30/02 ,  H04N5/76 ,  H04N21/4147 ,  H04N21/432 ,  H04N21/4335 ,  H04N21/45 ,  H04N21/458 ,  H04N21/488 ,  H04N21/81 ,  H04N21/482 ,  H04N5/765 ,  H04N5/775 ,  H04N5/781 ,  H04N5/907

CPC分类号： H04N21/47217 ,  G06Q30/0241 ,  H04N5/76 ,  H04N5/765 ,  H04N5/775 ,  H04N5/7755 ,  H04N5/781 ,  H04N5/907 ,  H04N21/4147 ,  H04N21/432 ,  H04N21/4325 ,  H04N21/4335 ,  H04N21/4532 ,  H04N21/458 ,  H04N21/472 ,  H04N21/482 ,  H04N21/4882 ,  H04N21/812

摘要： Methods and apparatuses for presenting targeted advertisements to DVR users are described. After a DVR has finished playing a recorded television program, or in response to other specified events, the DVR presents a screen which comprises a “save or delete” menu. In addition to the “save” and “delete” options, the menu additionally comprises one or more other options. Each of these other options may correspond to a separate promotional item. For example, a user's selection of such an option may cause the DVR to display or play an advertisement on the user's television set. Additionally or alternatively, these other options, when selected by a user, may cause the DVR to display a user interface through which the user can actually purchase a product or service. The product or service advertised or offered may be one that was featured or referenced in the television program that the user was just watching.

公开(公告)号：US20080038201A1

公开(公告)日：2008-02-14

申请号：US11734576

申请日：2007-04-12

申请人： Bruce Klein ,  Julie Nemecek ,  Marcel Wuethrich

发明人： Bruce Klein ,  Julie Nemecek ,  Marcel Wuethrich

IPC分类号： A61K49/00 ,  A61K39/00 ,  A61P31/10 ,  C12N1/14 ,  C12Q1/48

CPC分类号： A61K39/0002 ,  A61K2039/522 ,  C12Q1/025 ,  C12Q1/485

摘要： A method of screening a compound for anti-fungal properties comprising the steps of exposing a test compound to a fungal histidine kinase, and determining whether kinase activity is inhibited, wherein inhibition of kinase activity indicates that the compound has anti-fungal properties is disclosed.

摘要翻译： 一种筛选化合物用于抗真菌性质的方法，包括以下步骤：将测试化合物暴露于真菌组氨酸激酶，以及确定激酶活性是否被抑制，其中激酶活性的抑制表明该化合物具有抗真菌性质。

公开(公告)号：US20130164766A1

公开(公告)日：2013-06-27

申请号：US13720513

申请日：2012-12-19

申请人： Bruce Klein ,  Theodore Brandhorst

发明人： Bruce Klein ,  Theodore Brandhorst

IPC分类号： C07K14/37 ,  G01N33/68

CPC分类号： C07K14/37 ,  C07K2319/00 ,  C07K2319/02 ,  G01N33/56961 ,  G01N33/6893

摘要： Methods for obtaining highly pure native, recombinant or modified BAD-1 protein include the steps of culturing a population of microbes expressing BAD-1 protein in a culture medium, collecting the population of microbes from the culture medium, obtaining a BAD-1 protein-containing solution, and purifying the BAD-1 protein from the solution by combining the BAD-1 protein-containing solution with a nickel-chelating resin, washing the nickel-chelating resin to remove unbound matter, and eluting the BAD-1 protein from the nickel-chelating resin. Highly pure native BAD-1 protein may be used in diagnostic kits for detecting Blastomyces dermatitidis infections in animals.

摘要翻译： 用于获得高纯天然，重组或修饰的BAD-1蛋白的方法包括在培养基中培养表达BAD-1蛋白的微生物群体的步骤，从培养基中收集微生物群体，获得BAD-1蛋白 - 通过将含有BAD-1蛋白的溶液与镍螯合树脂混合，从溶液中纯化BAD-1蛋白质，洗涤镍螯合树脂以除去未结合的物质，并将BAD-1蛋白从 镍螯合树脂。 高纯度的天然BAD-1蛋白可用于诊断试剂盒，用于检测动物中的皮肤真菌感染。

公开(公告)号：US20070300263A1

公开(公告)日：2007-12-27

申请号：US11492281

申请日：2006-07-24

申请人： James M. Barton ,  Paul Stevens ,  David Sandford ,  Robin Hayes ,  Margret Schmidt ,  Bruce Klein

发明人： James M. Barton ,  Paul Stevens ,  David Sandford ,  Robin Hayes ,  Margret Schmidt ,  Bruce Klein

IPC分类号： H04N7/173 ,  H04H9/00 ,  H04N7/10 ,  G06F13/00 ,  G06F3/00 ,  H04N7/16 ,  H04N5/445

CPC分类号： H04N21/47217 ,  G06Q30/0241 ,  H04N5/76 ,  H04N5/765 ,  H04N5/775 ,  H04N5/7755 ,  H04N5/781 ,  H04N5/907 ,  H04N21/4147 ,  H04N21/432 ,  H04N21/4325 ,  H04N21/4335 ,  H04N21/4532 ,  H04N21/458 ,  H04N21/472 ,  H04N21/482 ,  H04N21/4882 ,  H04N21/812

摘要： Methods and apparatuses for presenting targeted advertisements to DVR users are described. After a DVR has finished playing a recorded television program, or in response to other specified events, the DVR presents a screen which comprises a “save or delete” menu. In addition to the “save” and “delete” options, the menu additionally comprises one or more other options. Each of these other options may correspond to a separate promotional item. For example, a user's selection of such an option may cause the DVR to display or play an advertisement on the user's television set. Additionally or alternatively, these other options, when selected by a user, may cause the DVR to display a user interface through which the user can actually purchase a product or service. The product or service advertised or offered may be one that was featured or referenced in the television program that the user was just watching.

摘要翻译： 描述了向DVR用户呈现定向广告的方法和装置。 在DVR播放录制的电视节目之后，或者响应于其他指定的事件，DVR呈现包括“保存或删除”菜单的屏幕。 除了“保存”和“删除”选项之外，菜单还包括一个或多个其他选项。 这些其他选项中的每一个可以对应于单独的促销项目。 例如，用户对这种选项的选择可能导致DVR在用户的电视机上显示或播放广告。 另外或替代地，当由用户选择时，这些其他选项可能导致DVR显示用户实际可以通过其购买产品或服务的用户界面。 广告或提供的产品或服务可能是在用户正在观看的电视节目中被特征或引用的产品或服务。