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    Module for detecting analytes in fluids and chip having the same
    1.
    发明授权
    Module for detecting analytes in fluids and chip having the same 有权
    用于检测流体中的分析物和具有相同的芯片的模块

    公开(公告)号：US08828334B2

    公开(公告)日：2014-09-09

    申请号：US12667374

    申请日：2008-07-23

    申请人： Jun Ha Park ,  Chang Seop Lee ,  Hyun Chang Lim ,  Chan Il Chung ,  Jun Keun Chang

    发明人： Jun Ha Park ,  Chang Seop Lee ,  Hyun Chang Lim ,  Chan Il Chung ,  Jun Keun Chang

    IPC分类号： B01L99/00 ,  B01L3/00

    CPC分类号： B01L3/502753 ,  B01L3/5027 ,  B01L2300/0681 ,  B01L2300/0825 ,  B01L2400/0406 ,  G01N33/491

    摘要： Disclosed is a module for rapidly detecting analytes in fluids with high effectiveness and a chip having the module. The module includes a microchannel, which has a filtering zone for removing noise materials and a reaction zone wherein labeling reaction and immobilization reaction for detection of analytes are performed, sample fluid moving through the microchannel due to capillary floating. In a case where the chip having the module is used in detecting analytes in fluids, it is possible to minimize dead volume of sample fluid so that high effective volume ratio can be implemented. Therefore, the chip can be used in detecting analytes from the minimum amount of sample fluid.

    摘要翻译： 公开了一种用于快速检测具有高效率的流体中的分析物和具有该模块的芯片的模块。 该模块包括具有用于去除噪声材料的过滤区和反应区的微通道，其中执行用于检测分析物的标记反应和固定反应，由于毛细管漂浮而移动通过微通道的样品流体。 在具有模块的芯片用于检测流体中的分析物的情况下，可以使样品流体的死体积最小化，从而可以实现高有效体积比。 因此，该芯片可用于从最小量的样品流体中检测分析物。

    Chip for analyzing fluids
    2.
    发明授权
    Chip for analyzing fluids 有权
    用于分析流体的芯片

    公开(公告)号：US08591831B2

    公开(公告)日：2013-11-26

    申请号：US12667371

    申请日：2008-07-23

    申请人： Jun Ha Park ,  Chan Il Chung ,  Jun Keun Chang

    发明人： Jun Ha Park ,  Chan Il Chung ,  Jun Keun Chang

    IPC分类号： B01L99/00

    CPC分类号： B01L3/502746 ,  B01L3/502723 ,  B01L2300/0825 ,  B01L2300/0887 ,  B01L2300/089 ,  B01L2400/0406 ,  B01L2400/084

    摘要： A fluid analysis chip includes a channel formed within the chip. The chip includes a sample inlet and a sample outlet communicating with an outside of the chip, where the sample inlet and the sample outlet communicate with each other through the closed channel. An expanding part of the channel is formed in a longitudinal direction of the channel in such a manner that a pair of inner walls of the channel define an inner surface of the expanding part, and the expanding part has a larger sectional area than the channel.

    摘要翻译： 流体分析芯片包括形成在芯片内的通道。 芯片包括与芯片外部连通的样品入口和样品出口，其中样品入口和样品出口通过封闭通道彼此连通。 通道的扩展部分沿通道的纵向方向形成，使得通道的一对内壁限定扩张部分的内表面，并且扩张部分具有比通道更大的截面面积。

    MODULE FOR DETECTING ANALYTES IN FLUIDS AND CHIP HAVING THE SAME
    3.
    发明申请
    MODULE FOR DETECTING ANALYTES IN FLUIDS AND CHIP HAVING THE SAME 有权
    用于检测流体中的分析物和具有该分析物的芯片的模块

    公开(公告)号：US20110294197A1

    公开(公告)日：2011-12-01

    申请号：US12667374

    申请日：2008-07-23

    申请人： Jun Ha Park ,  Chang Seop Lee ,  Hyun Chang Lim ,  Chan Il Chung ,  Jun Keun Chang

    发明人： Jun Ha Park ,  Chang Seop Lee ,  Hyun Chang Lim ,  Chan Il Chung ,  Jun Keun Chang

    IPC分类号： C12M1/34 ,  G01N33/48

    CPC分类号： B01L3/502753 ,  B01L3/5027 ,  B01L2300/0681 ,  B01L2300/0825 ,  B01L2400/0406 ,  G01N33/491

    摘要： Disclosed is a module for rapidly detecting analytes in fluids with high effectiveness and a chip having the module. The module includes a microchannel, which has a filtering zone for removing noise materials and a reaction zone wherein labeling reaction and immobilization reaction for detection of analytes are performed, sample fluid moving through the microchannel due to capillary floating. In a case where the chip having the module is used in detecting analytes in fluids, it is possible to minimize dead volume of sample fluid so that high effective volume ratio can be implemented. Therefore, the chip can be used in detecting analytes from the minimum amount of sample fluid.

    摘要翻译： 公开了一种用于快速检测具有高效率的流体中的分析物和具有该模块的芯片的模块。 该模块包括具有用于去除噪声材料的过滤区和反应区的微通道，其中执行用于检测分析物的标记反应和固定反应，由于毛细管漂浮而移动通过微通道的样品流体。 在具有模块的芯片用于检测流体中的分析物的情况下，可以使样品流体的死体积最小化，从而可以实现高有效体积比。 因此，该芯片可用于从最小量的样品流体中检测分析物。

    CHIP FOR ANALYZING FLUIDS
    5.
    发明申请
    CHIP FOR ANALYZING FLUIDS 有权

    公开(公告)号：US20110030458A1

    公开(公告)日：2011-02-10

    申请号：US12667371

    申请日：2008-07-23

    申请人： Jun Ha Park ,  Chan Il Chung ,  Jun Keun Chang

    发明人： Jun Ha Park ,  Chan Il Chung ,  Jun Keun Chang

    IPC分类号： G01N33/48

    CPC分类号： B01L3/502746 ,  B01L3/502723 ,  B01L2300/0825 ,  B01L2300/0887 ,  B01L2300/089 ,  B01L2400/0406 ,  B01L2400/084

    摘要： Disclosed is a fluid analysis chip including a microchannel formed within the chip. The chip includes a sample and a sample outlet communicating with an outside of the chip, and has a structure where the sample inlet and the sample outlet communicate with each other through the closed channel. An expanding part formed in a longitudinal direction of a channel in such a manner that a pair of inner walls corresponding to each other has a larger sectional area at a part or a whole thereof is formed. Therefore, fluids, which pass through the channel adjacent to the expanding part, move while making contact with only another pair of inner walls of the channel, which correspond to each other.

    Pipette tip for electroporation device
    8.
    发明授权
    Pipette tip for electroporation device 有权
    移植装置的移液器尖端

    公开(公告)号：US09523071B2

    公开(公告)日：2016-12-20

    申请号：US13060682

    申请日：2009-04-15

    申请人： Jun-Keun Chang ,  Keun-Chang Cho ,  Chan-Il Chung ,  Neon-Cheol Jung ,  Seung Gin Huh

    发明人： Jun-Keun Chang ,  Keun-Chang Cho ,  Chan-Il Chung ,  Neon-Cheol Jung ,  Seung Gin Huh

    IPC分类号： C12M1/00 ,  B01L3/00 ,  C12M1/42

    CPC分类号： C12M35/02

    摘要： Provided herein is a pipette tip (600) for electroporation including an outer surface, a void (611) located within the outer surface, and a conductor (622) located at least partially on or within the outer surface, in electrical communication with at least a portion of the outer surface and the void. Further provided herein is a pipette tip for electroporation including a body, a connector (620), and an elongated part (630). The connector is located at the distal end of the body and further includes at least one connecting post, a connecting part in mechanical communication with the connector, and a conductor located at least partially on or within the connector, wherein the conductor surrounds at least a portion of the connecting post. The elongated part also has a void and is located at the distal end of the connector. The void of the body, connector, and elongated part are in fluid communication.

    摘要翻译： 本文提供了一种用于电穿孔的移液管尖端（600），其包括外表面，位于外表面内的空隙（611）和至少部分地位于外表面上或外表面上的导体（622），至少与 外表面和空隙的一部分。 本文进一步提供用于电穿孔的移液管末端，其包括主体，连接器（620）和细长部分（630）。 连接器位于主体的远端，并且还包括至少一个连接柱，与连接器机械连通的连接部分和至少部分地位于连接器上或内部的导体，其中导体至少围绕 连接柱的一部分。 细长部分还具有空隙并且位于连接器的远端。 主体，连接器和细长部件的空隙处于流体连通状态。

    FLUORESCENT MICROSCOPE FOR OBSERVING MULTIPLE FLUORESCENT IMAGES, FLUORESCENT IMAGE SURVEYING METHOD USING THE SAME, AND MULTIPLE FLUORESCENT IMAGE OBSERVING SYSTEM
    9.
    发明申请
    FLUORESCENT MICROSCOPE FOR OBSERVING MULTIPLE FLUORESCENT IMAGES, FLUORESCENT IMAGE SURVEYING METHOD USING THE SAME, AND MULTIPLE FLUORESCENT IMAGE OBSERVING SYSTEM 有权
    用于观察多个荧光图像的荧光显微镜，使用其的荧光图像测量方法和多个荧光图像观察系统

    公开(公告)号：US20130201322A1

    公开(公告)日：2013-08-08

    申请号：US13809319

    申请日：2011-08-18

    申请人： Hwa Joon Park ,  Jeoung Ku Hwang ,  Jee Young Kim ,  Chan Il Chung

    发明人： Hwa Joon Park ,  Jeoung Ku Hwang ,  Jee Young Kim ,  Chan Il Chung

    IPC分类号： G02B21/00

    CPC分类号： G02B21/0076 ,  G01N2021/6419 ,  G01N2021/6421 ,  G02B21/0064 ,  G02B21/16 ,  G02B2207/113

    摘要： A fluorescent microscope for observing multiple fluorescent images includes: a first optical module comprising a first light source for supplying first excitation light having a first wavelength, a first excitation filter for selectively transmitting the first excitation light supplied from the first light source, a first dichroic filter for reflecting the first excitation light having passed through the first excitation filter toward the survey object, an objective lens for condensing the first excitation light reflected by the first dichroic filter and transferring the condensed first excitation light to the survey object, a second dichroic filter for reflecting first radiation light radiated from the survey object, a first radiation filter for selectively transmitting the first radiation light reflected by the second dichroic filter, and a first image acquisition unit for acquiring an image by using the first radiation light having passed through the first radiation filter to be supplied; and a second optical module comprising a second light source for supplying second excitation light having a second wavelength, a second excitation filter for selectively transmitting the second excitation light supplied from the second light source, a second radiation filter passing through the second excitation filter and irradiated to the survey object to be radiated, to selectively transmitting the second radiation light EM2 having passed through the objective lens, the first dichroic filter, and the second excitation filter, and a second image acquisition unit for acquiring an image by using the second radiation light having passed through the second radiation filter to be supplied.

    摘要翻译： 用于观察多个荧光图像的荧光显微镜包括：第一光学模块，包括用于提供具有第一波长的第一激发光的第一光源，用于选择性地透射从第一光源提供的第一激发光的第一激发滤光器，第一二色性 滤光器，用于将通过第一激发滤光器的第一激发光朝向测量对象反射;物镜，用于会聚由第一分色滤光器反射的第一激发光并将聚集的第一激发光转印到测量对象;第二二向色滤光片 用于反射从所述测量对象辐射的第一辐射光，用于选择性地透射由所述第二分色滤光器反射的所述第一辐射光的第一辐射滤光器;以及第一图像获取单元，用于通过使用已经穿过所述第一 辐射过滤器为sup 合并 以及第二光学模块，包括用于提供具有第二波长的第二激发光的第二光源，用于选择性地透射从第二光源提供的第二激发光的第二激发滤光器，穿过第二激发滤光器并照射的第二辐射滤光片 到要被辐射的测量对象，以选择性地透过已经通过物镜的第二辐射光EM2，第一二向色滤光器和第二激发滤光器，以及第二图像获取单元，用于通过使用第二辐射光获取图像 已通过要供应的第二辐射滤波器。

    PIPETTE TIP FOR ELECTROPORATION DEVICE
    10.
    发明申请
    PIPETTE TIP FOR ELECTROPORATION DEVICE 有权
    电气设备管件

    公开(公告)号：US20110263005A1

    公开(公告)日：2011-10-27

    申请号：US13060682

    申请日：2009-04-15

    申请人： Jun-Keun Chang ,  Keun-Chang Cho ,  Chan-Il Chung ,  Neon-Cheol Jung ,  Seung Gin Huh

    发明人： Jun-Keun Chang ,  Keun-Chang Cho ,  Chan-Il Chung ,  Neon-Cheol Jung ,  Seung Gin Huh

    IPC分类号： C12M1/42

    CPC分类号： C12M35/02

    摘要： Provided herein is a pipette tip (600) for electroporation including an outer surface, a void (611) located within the outer surface, and a conductor (622) located at least partially on or within the outer surface, in electrical communication with at least a portion of the outer surface and the void. Further provided herein is a pipette tip for electroporation including a body, a connector (620), and an elongated part (630). The connector is located at the distal end of the body and further includes at least one connecting post, a connecting part in mechanical communication with the connector, and a conductor located at least partially on or within the connector, wherein the conductor surrounds at least a portion of the connecting post. The elongated part also has a void and is located at the distal end of the connector. The void of the body, connector, and elongated part are in fluid communication.

    摘要翻译： 本文提供了一种用于电穿孔的移液管尖端（600），其包括外表面，位于外表面内的空隙（611）和至少部分地位于外表面上或外表面上的导体（622），至少与 外表面和空隙的一部分。 本文进一步提供用于电穿孔的移液管末端，其包括主体，连接器（620）和细长部分（630）。 连接器位于主体的远端，并且还包括至少一个连接柱，与连接器机械连通的连接部分和至少部分地位于连接器上或内部的导体，其中导体至少围绕 连接柱的一部分。 细长部分还具有空隙并且位于连接器的远端。 主体，连接器和细长部分的空隙处于流体连通状态。