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公开(公告)号：US6020963A
公开(公告)日：2000-02-01
申请号：US985691
申请日：1997-12-05
申请人： Charles A. DiMarzio
发明人： Charles A. DiMarzio
CPC分类号： G01B9/02081 , G01B9/02024 , G01N21/4795 , G01B2290/45 , G01B2290/70
摘要： An optical quadrature interferometer is presented. The optical quadrature interferometer uses a different state of polarization in each of two arms of the interferometer. A light beam is split into two beams by a beamsplitter, each beam directed to a respective arm of the interferometer. In one arm, the measurement arm, the light beam is directed through a linear polarizer and a quarter wave plate to produce circularly polarized light, and then to a target being measured. In the other arm, the reference arm, the light beam is not subject to any change in polarization. After the light beams have traversed their respective arms, the light beams are combined by a recombining beamsplitter. As such, upon the beams of each arm being recombined, a polarizing element is used to separate the combined light beam into two separate fields which are in quadrature with each other. An image processing algorithm can then obtain the in-phase and quadrature components of the signal in order to construct an image of the target based on the magnitude and phase of the recombined light beam. The system may further be used for lensless imaging.
摘要翻译： 提出了一种光学正交干涉仪。 光学正交干涉仪在干涉仪的两个臂中的每一个中使用不同的偏振状态。 光束被分束器分成两束，每束光束指向干涉仪的相应臂。 在一个臂中，测量臂，光束被引导通过线性偏振器和四分之一波片以产生圆偏振光，然后到被测量的目标。 在另一个臂中，参考臂，光束不会发生极化变化。 在光束穿过其各自的臂之后，光束通过重组分束器组合。 因此，在每个臂的光束被复合时，使用偏振元件将组合的光束分离成彼此成正交的两个分离的场。 然后，图像处理算法可以获得信号的同相和正交分量，以便基于重新组合的光束的大小和相位来构建目标的图像。 该系统还可以用于无镜头成像。
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公开(公告)号：US07792570B2
公开(公告)日：2010-09-07
申请号：US11101111
申请日：2005-04-07
申请人： Charles A. DiMarzio , Luis A. Nieva
发明人： Charles A. DiMarzio , Luis A. Nieva
IPC分类号： A61B6/00
CPC分类号： A61B5/0048 , A61B5/0059 , A61B5/0064 , A61B5/0066 , A61B5/0068 , A61B5/0095 , A61B5/441
摘要： A microscopy apparatus includes a heating source to provide a pulse of heating energy focused on a target to heat a localized region of the target, such as human tissue, to generate motion. A measuring source provides a measuring light beam focused on the target. A coherent confocal microscopy assembly focuses the measuring light beam on the target and returns a reflected signal from the target. A detection assembly receives the reflected signal from the target and detects a Doppler shift of the reflected signal. A scanning assembly scans pulses from the heating source over the target and scans the measuring light beam from the measuring source over the target to build up an image of a plane of the target.
摘要翻译： 显微镜装置包括加热源，以提供聚焦在靶上的加热能量的脉冲，以加热诸如人体组织的靶的局部区域，以产生运动。 测量源提供聚焦在目标上的测量光束。 相干共焦显微镜组件将测量光束聚焦在目标上，并从目标返回反射信号。 检测组件从目标接收反射信号并检测反射信号的多普勒频移。 扫描组件从目标上的加热源扫描脉冲，并从目标上的测量源扫描测量光束，以建立目标平面的图像。
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3.发明授权Method and apparatus for performing magnetic field measurements using magneto-optic Kerr effect sensors 失效使用磁光克尔效应传感器进行磁场测量的方法和装置
公开(公告)号：US5736856A
公开(公告)日：1998-04-07
申请号：US744923
申请日：1996-11-06
IPC分类号： G01B11/16 , G01D5/34 , G01R33/032 , G02F1/09
CPC分类号： G01B11/18 , G01D5/344 , G01R33/0325
摘要： A sensor system includes a magneto-optic Kerr effect magnetic field sensing element and an optical system including a light source, at least one polarizer or polarizing element and a detector disposed about the sensing element. The sensing element is responsive to an external magnetic field. In one embodiment, the optical system and sensing element can be arranged to measure the strength of a magnetic field. In another embodiment the optical system and sensing element can be arranged to measure the rotational speed of rotating members.
摘要翻译： 传感器系统包括磁光克尔效应磁场感测元件和包括光源，至少一个偏振器或偏振元件的光学系统和围绕传感元件设置的检测器。 感测元件响应于外部磁场。 在一个实施例中，光学系统和感测元件可被布置成测量磁场的强度。 在另一个实施例中，光学系统和感测元件可被布置成测量旋转构件的旋转速度。
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4.发明授权公开(公告)号：US08816279B2
公开(公告)日：2014-08-26
申请号：US13084287
申请日：2011-04-11
申请人： Max Diem , Charles A. Dimarzio
发明人： Max Diem , Charles A. Dimarzio
IPC分类号： H01L31/0232
CPC分类号： H01L27/14875 , H01L27/14649 , H04N5/33
摘要： Methods, devices, and systems for imaging tissue and other samples or samples using infrared (IR) transmissions from coherent transmission sources, such as a wide range, tunable, quantum cascade laser (QCL) designed for the rapid collection of infrared microscopic data for medical diagnostics across a wide range of discrete spectral increments. The infrared transmissions are transmitted through, reflected from, and/or transreflected through a sample, and then magnified and/or focused prior to being detected by a detector. After detection, the sample related image data is used to assess the sample. Such methods, devices, and systems may be used to detect abnormalities in tissue, for example, before such abnormalities can be diagnosed using art cytopathological methods. The methods, devices and systems may also optionally include a visible light detection subsystem and/or a motion control subsystem to assist in control and processing of imaging.
摘要翻译： 用于使用来自相干传输源的红外（IR）传输成像组织和其他样品或样品的方法，装置和系统，例如宽范围，可调谐的量子级联激光器（QCL），其被设计用于快速收集用于医疗的红外微观数据 诊断跨越广泛的离散频谱增量。 红外线传输通过样品透射，反射和/或透反射，然后在被检测器检测到之前被放大和/或聚焦。 检测后，样品相关图像数据用于评估样品。 可以使用这样的方法，装置和系统来检测组织中的异常，例如在使用美术细胞病理学方法诊断出这种异常之前。 方法，装置和系统还可以可选地包括可见光检测子系统和/或运动控制子系统，以帮助控制和处理成像。
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5.发明授权Enhanced detection of acousto-photonic emissions in optically turbid media using a photo-refractive crystal-based detection system 失效使用基于光折射晶体的检测系统增强光学混浊介质中声光发射的检测公开(公告)号：US07652773B2
公开(公告)日：2010-01-26
申请号：US10586713
申请日：2005-01-20
申请人： Charles A. DiMarzio , Ronald A. Roy , Todd W. Murray , Florian J. Blonigen , Luis A. Nieva , Lei Sui , Gopi Maguluri
发明人： Charles A. DiMarzio , Ronald A. Roy , Todd W. Murray , Florian J. Blonigen , Luis A. Nieva , Lei Sui , Gopi Maguluri
IPC分类号： G01B9/02
CPC分类号： G01N21/4795 , G01N29/0672 , G01N29/2418 , G01N29/346 , G01N2291/02466 , G01N2291/02872 , G01N2291/0427
摘要： A system and method of detecting acousto-photonic emissions in optically turbid media that provide increased levels of detection sensitivity. The detection system includes an ultrasonic transducer, a laser, a photo-detector for detecting ultrasound-modulated laser light, and circuitry for processing the detected signals for subsequent analysis. The ultrasonic transducer generates an ultrasonic wave that propagates within an optically turbid medium. The laser generates a coherent light beam, which is split to form signal and reference beams. The signal beam is sent through the turbid medium, where it is phase modulated by the ultrasound. The ultrasound-modulated signal beam is provided to a photo-refractive crystal for subsequent interference with the reference beam to convert the phase modulation to intensity modulation. The DC offset of the signal beam intensity provides a measure of the magnitude of the mean phase shift induced by the ultrasound on the multiply scattered optical field within the turbid medium.
摘要翻译： 一种在光学混浊介质中检测声光发射的系统和方法，其提供更高水平的检测灵敏度。 检测系统包括超声波换能器，激光器，用于检测超声调制激光的光检测器，以及用于处理检测信号以用于后续分析的电路。 超声波换能器产生在光学混浊介质内传播的超声波。 激光产生相干光束，其被分离以形成信号和参考光束。 信号光束通过混浊介质传送，在那里它被超声波相位调制。 超声调制信号光束被提供给光折射晶体，用于随后与参考光束的干涉，以将相位调制转换成强度调制。 信号光束强度的直流偏移提供了在混浊介质内的多重散射光场上由超声引起的平均相移幅度的量度。
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6.发明授权Apparatus and method for measuring instantaneous power using a magneto-optic Kerr effect sensor 失效使用磁光克尔效应传感器测量瞬时功率的装置和方法
公开(公告)号：US5994898A
公开(公告)日：1999-11-30
申请号：US948431
申请日：1997-10-10
IPC分类号： G01R33/032 , G01R19/00 , G02F1/09
CPC分类号： G01R33/0325
摘要： An apparatus and method for measuring instantaneous power using a magneto-optic Kerr effect sensor are disclosed. The apparatus comprises and the method requires a magneto-optic Kerr effect magnetic field sensing element and an optical system including a light source, first and second polarizers, and a photoconductive detector. In a preferred embodiment, the sensing element and the optical system are arranged to sense the intensity of a magnetic field generated by current passing through a high voltage power line so as to provide an optical signal that is representative of the current to the photoconductive detector. A voltage signal is tapped off of the high voltage power line to provide a bias signal to the photoconductive detector. The photoconductive detector thereby effectively multiplies the optical current signal with the voltage signal so as to provide a photoconductive detector current signal that is proportional to instantaneous power passing through the high voltage power line.
摘要翻译： 公开了一种使用磁光克尔效应传感器测量瞬时功率的装置和方法。 该装置包括并且该方法需要磁光克尔效应磁场感测元件和包括光源，第一和第二偏振器以及光电导检测器的光学系统。 在优选实施例中，感测元件和光学系统布置成感测通过高压电力线的电流产生的磁场的强度，以便提供代表到光电导检测器的电流的光信号。 电压信号从高电压电源线上抽出，以向光电检测器提供偏置信号。 因此，光导检测器有效地将光电流信号与电压信号相乘，以提供与通过高压电力线的瞬时功率成比例的光电导检测器电流信号。
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公开(公告)号：US5825018A
公开(公告)日：1998-10-20
申请号：US583851
申请日：1996-01-11
CPC分类号： G01J9/04 , G01S7/4914 , H03D9/00 , G01J2001/4242
摘要： An optical lock-in detection technique and circuit for coherent applications employing a photo-detector having a symmetric I-V curve is presented. The detection circuit includes a photo-detector operating as an optical lock-in amplifier, and a modulation source. The technique and circuit are used for coherent detection applications such as the determination of the frequency of modulation of an optical signal or the determination of the presence of an optical signal at a specified frequency. The technique and circuit are also used with one or more charge coupled devices in imaging applications.
摘要翻译： 提出了一种使用具有对称I-V曲线的光电检测器的相干应用的光锁定检测技术和电路。 检测电路包括作为光学锁相放大器工作的光检测器和调制源。 技术和电路用于相干检测应用，例如确定光信号的调制频率或确定在特定频率下的光信号的存在。 技术和电路也与成像应用中的一个或多个电荷耦合器件一起使用。
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8.发明授权Method and apparatus for performing magnetic field measurements using magneto-optic kerr effect sensors 失效使用磁光克尔效应传感器进行磁场测量的方法和装置
公开(公告)号：US5631559A
公开(公告)日：1997-05-20
申请号：US474692
申请日：1995-06-07
IPC分类号： G01B11/16 , G01D5/34 , G01R33/032 , G01P3/36
CPC分类号： G01B11/18 , G01D5/344 , G01R33/0325
摘要： A sensor system includes a magneto-optic Kerr effect magnetic field sensing element and an optical system including a light source, at least one polarizer or polarizing element and a detector disposed about the sensing element. The sensing element is responsive to an external magnetic field. In one embodiment, the optical system and sensing element can be arranged to measure the strength of a magnetic field. In another embodiment the optical system and sensing element can be arranged to measure the rotational speed of rotating members.
摘要翻译： 传感器系统包括磁光克尔效应磁场感测元件和包括光源，至少一个偏振器或偏振元件的光学系统和围绕传感元件设置的检测器。 感测元件响应于外部磁场。 在一个实施例中，光学系统和感测元件可被布置成测量磁场的强度。 在另一个实施例中，光学系统和感测元件可被布置成测量旋转构件的旋转速度。
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公开(公告)号：US5493220A
公开(公告)日：1996-02-20
申请号：US26589
申请日：1993-03-05
IPC分类号： G01B11/16 , G01D5/34 , G01R33/032 , G01B7/24 , G02F1/09
CPC分类号： G01R33/0325 , G01B11/18 , G01D5/344
摘要： A sensor system including a magnetooptic sensing element, a light source, at least one polarizer and at least one detector disposed about the sensing element. The sensing element has a first characteristic such that the sensing element provides a response to an applied external stress.
摘要翻译： 包括磁光感测元件，光源，至少一个偏振器和围绕传感元件设置的至少一个检测器的传感器系统。 感测元件具有第一特性，使得感测元件对施加的外部应力提供响应。
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10.发明申请DEEP TISSUE FOCAL FLUORESCENCE IMAGING WITH DIGITALLY TIME-REVERSED ULTRASOUND-ENCODED LIGHT 有权DEEP TISSUE FOCAL荧光成像与数字时间反转超声波编码光公开(公告)号：US20130342665A1
公开(公告)日：2013-12-26
申请号：US13851901
申请日：2013-03-27
IPC分类号： H04N5/30
CPC分类号： H04N5/30 , A61N5/00 , G01N27/44721 , G02F1/11
摘要： A device and method for performing fluorescence imaging with digitally time reversed ultrasound encoded light, using a source of ultrasound waves, a coherent light source, a digital optical phase conjugation (DOPC) device comprising a camera and a spatial light modulator (SLM), a detector of fluorescence, and one or more computers, to obtain an output that at least approximates an interaction between a complete time reversed field, of all of the encoded light's fields, and the scattering medium.
摘要翻译： 使用超声波源，相干光源，包括照相机和空间光调制器（SLM）的数字光学相位共轭（DOPC）装置，用数字时间反转的超声波编码光进行荧光成像的装置和方法， 荧光检测器和一个或多个计算机，以获得至少近似于所有编码光场的完整时间反转场与散射介质之间的相互作用的输出。
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