利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

16 条记录 (耗时 0.014 秒)

    PHARMACEUTICAL COMPOSITIONS FOR RELEASE CONTROL OF METHYLPHENIDATE
    1.
    发明申请
    PHARMACEUTICAL COMPOSITIONS FOR RELEASE CONTROL OF METHYLPHENIDATE 有权
    药物组合物用于释放甲基苯甲酸酯的控制

    公开(公告)号：US20110223247A1

    公开(公告)日：2011-09-15

    申请号：US13126855

    申请日：2009-11-06

    申请人： Sang Yeob Park ,  Hojin Chung ,  Chaul Min Pai

    发明人： Sang Yeob Park ,  Hojin Chung ,  Chaul Min Pai

    IPC分类号： A61K9/58 ,  A61K9/00 ,  A61K9/22 ,  A61K9/54 ,  A61K31/445 ,  A61P25/00 ,  A61K9/56

    CPC分类号： A61K9/0095 ,  A61K9/0056 ,  A61K9/5073 ,  A61K31/445

    摘要： Disclosed is a pharmaceutical composition for release control comprising a plurality of particles for release control. The plurality of particles for release control comprise a core material containing methylphenidate and a polymer coating layer for release control formed on the core material. The plurality of particles for release control are divided into two or more groups based on the average thickness of the polymer coating layer for release control. The particle groups are identical in terms of the composition of the polymer in the polymer coating layer, but are different in terms of the average thickness of the coated layer. The pharmaceutical composition for release control according to the present invention may control the release pattern of methylphenidate contained in the core material as desired, and can be used as an oral formulation in a variety of forms such as orally disintegrating tablets, etc.

    摘要翻译： 公开了一种用于释放控制的药物组合物，其包含多个用于释放控制的颗粒。 用于释放控制的多个颗粒包括含有哌甲酯的核心材料和用于在芯材上形成的用于释放控制的聚合物涂层。 用于释放控制的多个颗粒基于用于释放控制的聚合物涂层的平均厚度被分成两组或更多组。 在聚合物涂层中聚合物的组成方面，颗粒组是相同的，但是在涂层的平均厚度方面是不同的。 根据本发明的用于释放控制的药物组合物可以根据需要控制核心材料中所含的哌甲酯的释放模式，并且可以以各种形式如口腔崩解片等的口服制剂使用。

    CONTROLLED-RELEASE PHARMACEUTICAL COMPOSITION INCLUDING TAMSULOSIN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND ORAL FORMULATION INCLUDING THE SAME
    2.
    发明申请
    CONTROLLED-RELEASE PHARMACEUTICAL COMPOSITION INCLUDING TAMSULOSIN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND ORAL FORMULATION INCLUDING THE SAME 审中-公开

    公开(公告)号：US20130052264A1

    公开(公告)日：2013-02-28

    申请号：US13695814

    申请日：2011-04-27

    申请人： Ho-Jin Chung ,  Sang-Yeob Park ,  Chaul-Min Pai

    发明人： Ho-Jin Chung ,  Sang-Yeob Park ,  Chaul-Min Pai

    IPC分类号： A61K9/58 ,  A61K9/32 ,  A61P13/02 ,  A61K9/08 ,  A61K31/18 ,  A61K9/14 ,  A61K9/16

    CPC分类号： A61K31/18 ,  A61K9/5073 ,  A61K9/5078 ,  A61K9/5084

    摘要： A controlled-release pharmaceutical composition including first and second groups of microparticles, each of the microparticles including a core including tamsulosin or pharmaceutically acceptable salts thereof, a controlled-release polymer coating layer formed on the core, and an enteric polymer outer layer formed on the controlled-release polymer coating layer, wherein the average thickness of the controlled-release polymer coating layer is different in each of the first and second groups of microparticles, and an oral formulation including the same, are provided. This pharmaceutical composition can easily control the extent of release of an active ingredient depending on changes in pH in the intestinal tract and the release pattern of the active ingredient in the small intestine, thus preventing the active ingredient from being rapidly transferred into the blood to thereby minimize side-effects, and maintaining the effective blood concentration of the active ingredient for a predetermined period of time. Furthermore, this composition can shield the bitter taste of the active ingredient even when exposed to the inside of the mouth, thus increasing the therapeutic effects for patients upon oral administration.

    Transdermal composition of an antivomiting agent
    7.
    发明授权
    Transdermal composition of an antivomiting agent 有权
    抗病毒剂的透皮组合物

    公开(公告)号：US07273619B2

    公开(公告)日：2007-09-25

    申请号：US10414827

    申请日：2003-04-15

    申请人： Chaul Min Pai ,  Jin Deog Song ,  Joong Woong Cho

    发明人： Chaul Min Pai ,  Jin Deog Song ,  Joong Woong Cho

    IPC分类号： A61F13/00 ,  A61F15/16

    CPC分类号： A61K9/0014 ,  A61K9/7023 ,  A61K31/00 ,  A61K31/46 ,  A61K47/10 ,  A61K47/14 ,  A61K47/18 ,  A61K47/38

    摘要： The present invention relates to a transdermal composition of an antivomiting agent, and more particularly to a transdermal composition of an antivomiting agent which can minimize skin irritation by employing tropisetron as the antivomiting agent as well as by adjusting its pH to be in the range of 8 to 9 thus enhancing its rate of skin penetration thereby reducing the amount of a skin penetration enhancer used.

    摘要翻译： 本发明涉及抗病毒剂的透皮组合物，更具体地说，涉及一种抗病毒剂的透皮组合物，其可以通过使用托烷司琼作为抗病毒剂，并通过将其pH调节至8范围内来最小化皮肤刺激 从而提高其皮肤渗透速率，从而减少使用的皮肤渗透增强剂的量。

    Highly plastic granules for making fast melting tablets
    9.
    发明授权
    Highly plastic granules for making fast melting tablets 失效
    用于制作快速熔融片的高度塑料颗粒

    公开(公告)号：US07749533B2

    公开(公告)日：2010-07-06

    申请号：US10841979

    申请日：2004-05-07

    申请人： Yourong Fu ,  Chaul Min Pai ,  Sang Yeob Park ,  Gun Seomoon ,  Kinam Park

    发明人： Yourong Fu ,  Chaul Min Pai ,  Sang Yeob Park ,  Gun Seomoon ,  Kinam Park

    IPC分类号： A61K9/20 ,  A61K9/16

    CPC分类号： A61K9/0056

    摘要： A fast-melting pharmaceutical tablet comprises a porous, plastic substance, a water penetration enhancer and a binder. One or more drugs can be incorporated into the formulation at different stages of the process so as to afford a pharmaceutically active tablet. Methods of making the pharmaceutical tablet entail combining the porous, plastic material, the water penetration enhancing agent, and the binder so as to form highly plastic granules, which are compressed into tablets. The resulting tablets dissolve rapidly in the mouth and have good hardness with low brittleness. The tablets are particularly valuable to those who have difficulty swallowing conventional pills.

    摘要翻译： 快速熔化的药物片剂包括多孔塑料物质，水渗透增强剂和粘合剂。 可以在该方法的不同阶段将一种或多种药物并入制剂中，从而得到药用活性片剂。 制备药片的方法需要结合多孔，塑料，水渗透增强剂和粘合剂，以形成高度塑性的颗粒，将其压制成片剂。 所得片剂迅速溶于口中，硬度好，脆性低。 这些片剂对吞咽常规药丸有困难的人特别有价值。