公开(公告)号：US20140350680A1

公开(公告)日：2014-11-27

申请号：US14367870

申请日：2012-12-22

申请人： Dang Quang Svend Le ,  Muwan Chen ,  Menglin Chen ,  Anette Overgaard Baatrup ,  Cody Eric Bünger ,  Helle Lysdahl ,  Jørgen Kjems ,  Morten Østergaard Andersen ,  Flemming Besenbacher

发明人： Dang Quang Svend Le ,  Muwan Chen ,  Menglin Chen ,  Anette Overgaard Baatrup ,  Cody Eric Bünger ,  Helle Lysdahl ,  Jørgen Kjems ,  Morten Østergaard Andersen ,  Flemming Besenbacher

IPC分类号： A61L27/14 ,  A61F2/10 ,  A61F2/28

CPC分类号： A61L27/14 ,  A61F2/105 ,  A61F2/28 ,  A61L27/34 ,  A61L27/50 ,  A61L29/085 ,  A61L29/14 ,  A61L31/10 ,  A61L31/14 ,  A61L2400/18

摘要： The present invention relates to a process for modifying the surface morphology of a medical device. The modified surface has, among other advantageous properties, an improved capacity for sorption or conjugation of a variety of bioactive agents, the addition of which will turn the medical device into a localized drug delivery system.

摘要翻译： 本发明涉及用于改变医疗装置的表面形态的方法。 改进的表面除了其它有利的性质之外还具有改进的各种生物活性剂的吸附或缀合的能力，其添加将将医疗装置转变成局部药物递送系统。

公开(公告)号：US08741631B2

公开(公告)日：2014-06-03

申请号：US13375785

申请日：2010-06-03

申请人： Dang Quang Svend Le ,  Jens Vinge Nygaard ,  Morten Foss ,  Flemming Besenbacher ,  Cody Bünger

发明人： Dang Quang Svend Le ,  Jens Vinge Nygaard ,  Morten Foss ,  Flemming Besenbacher ,  Cody Bünger

IPC分类号： C12M1/00 ,  C12M1/02 ,  B01F13/08 ,  C12M3/04 ,  C12M1/06

CPC分类号： C12M29/10 ,  B01F13/08 ,  B01F13/0827 ,  C12M27/00 ,  C12M27/02 ,  C12M27/10

摘要： A device for biological purposes such as cell culturing, enzymatic reactions or filtering of fluid has a body with first and second surfaces. The body is delimited by a rim and an aperture in the center of the body. The aperture is covered at the first and second surface by first and second plates. The first and/or second plate has an inlet orifice allowing liquid medium into the aperture. Rotating means are arranged in the aperture between the first and second plate. At least one recessed portion is a cavity in the rim of the body having a first outlet orifice allowing the liquid medium to flow out of the body. At least one outlet channel connects the circular aperture with the recessed portion. Liquid is pumped into the aperture of the device and pumped through at least one outlet channel.

摘要翻译： 用于生物学目的的装置如细胞培养，酶反应或流体过滤具有具有第一和第二表面的主体。 身体由身体中心的边缘和孔限定。 孔由第一和第二板覆盖在第一和第二表面。 第一和/或第二板具有允许液体介质进入孔的入口孔。 旋转装置布置在第一和第二板之间的孔中。 至少一个凹部是本体边缘中的空腔，其具有允许液体介质从身体流出的第一出口孔。 至少一个出口通道将圆形孔与凹部连接。 液体被泵送到设备的孔中并泵送通过至少一个出口通道。

公开(公告)号：US20120171718A1

公开(公告)日：2012-07-05

申请号：US13375785

申请日：2010-06-03

申请人： Dang Quang Svend Le ,  Jens Vinge Nygaard ,  Morten Foss ,  Flemming Besenbacher ,  Cody Bünger

发明人： Dang Quang Svend Le ,  Jens Vinge Nygaard ,  Morten Foss ,  Flemming Besenbacher ,  Cody Bünger

IPC分类号： C12M3/00 ,  B01D35/00 ,  C12M1/40 ,  C12N5/071 ,  C12P1/00

CPC分类号： C12M29/10 ,  B01F13/08 ,  B01F13/0827 ,  C12M27/00 ,  C12M27/02 ,  C12M27/10

摘要： A device for biological purposes such as cell culturing, enzymatic reactions or filtering of fluid has a body with first and second surfaces. The body is delimited by a rim and an aperture in the center of the body. The aperture is covered at the first and second surface by first and second plates. The first and/or second plate has an inlet orifice allowing liquid medium into the aperture. Rotating means are arranged in the aperture between the first and second plate. At least one recessed portion is a cavity in the rim of the body having a first outlet orifice allowing the liquid medium to flow out of the body. At least one outlet channel connects the circular aperture with the recessed portion. Liquid is pumped into the aperture of the device and pumped through at least one outlet channel.

摘要翻译： 用于生物学目的的装置如细胞培养，酶反应或流体过滤具有具有第一和第二表面的主体。 身体由身体中心的边缘和孔限定。 孔由第一和第二板覆盖在第一和第二表面。 第一和/或第二板具有允许液体介质进入孔的入口孔。 旋转装置布置在第一和第二板之间的孔中。 至少一个凹部是本体边缘中的空腔，其具有允许液体介质从身体流出的第一出口孔。 至少一个出口通道将圆形孔与凹部连接。 液体被泵送到设备的孔中并泵送通过至少一个出口通道。