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公开(公告)号：US08501305B2
公开(公告)日：2013-08-06
申请号：US12523496
申请日：2008-01-16
申请人： David Barlow
发明人： David Barlow
CPC分类号： B32B27/08 , B32B7/02 , B32B27/32 , B32B2307/31 , B32B2323/04 , B32B2323/10 , B32B2457/00 , Y10T428/24802 , Y10T428/24843 , Y10T428/24851 , Y10T428/24917 , Y10T428/24942 , Y10T428/249994 , Y10T428/269
摘要： The present invention relates to laminate comprising a first thermoplastic polymer layer with a first melt flow index, adjacent a thermoplastic polymer second layer with a second melt flow index, the first and second layer comprising the same thermoplastic polymer, characterized in that the first melt flow index is lower than the second melt flow index. The invention also relates to a microfluidic device comprising the laminate and a method for incorporating an ink pattern in the laminate.
摘要翻译： 本发明涉及包括具有第一熔体流动指数的第一热塑性聚合物层的层压体，邻近具有第二熔体流动指数的热塑性聚合物第二层，所述第一和第二层包含相同的热塑性聚合物，其特征在于，所述第一熔体流动 指数低于第二熔体流动指数。 本发明还涉及一种包括该层压体的微流体装置和一种将层叠体中的油墨图案结合的方法。
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公开(公告)号：US20130071303A1
公开(公告)日：2013-03-21
申请号：US13699379
申请日：2011-05-20
CPC分类号： B01L1/00 , B01L3/50857 , B01L2300/0816 , B01L2300/0825 , B01L2300/089 , B01L2300/165 , B32B37/06 , Y10T29/49 , Y10T156/10
摘要： A membrane incubation device, wherein the membrane incubation device is adapted to incubate sections of at least one membrane individually.
摘要翻译： 一种膜温育装置，其中所述膜孵育装置适于单独孵育至少一个膜的切片。
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公开(公告)号：US20050118661A1
公开(公告)日：2005-06-02
申请号：US10895590
申请日：2004-07-21
IPC分类号： A61K38/00 , C07K14/78 , G01N33/53 , G01N33/537 , G01N33/543 , G01N33/567 , G01N33/68
CPC分类号： G01N33/689 , A61K38/00 , C07K14/78 , G01N2333/78
摘要： A method is provided for assessing fertility status in female patient which comprises determining the level of fibronectin isoform EDIIIA+ and/or EDIIIB+ in an isolated endometrial sample within the implantation window time for the patient and correlating the appearance of said fibronectin isoform with fertility status. Fibronectin variants useful as contraceptive agents are also described.
摘要翻译： 提供了一种用于评估女性患者的生育状况的方法，其包括在患者的植入窗口时间内确定分离的子宫内膜样品中的纤连蛋白同种型EDIIIA +和/或EDIIIB +的水平，并将所述纤连蛋白同种型的外观与生育状态相关联。 也描述了可用作避孕剂的纤连蛋白变体。
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公开(公告)号：US06591844B2
公开(公告)日：2003-07-15
申请号：US09935906
申请日：2001-08-23
申请人： David Barlow , Dale G. Brown , Ian Roberts , Ira D. Hill , James McKenzie Hill
发明人： David Barlow , Dale G. Brown , Ian Roberts , Ira D. Hill , James McKenzie Hill
IPC分类号： A61C1500
CPC分类号： A61C15/00 , A61C15/041 , A61K8/4973 , A61K8/4993 , A61Q11/00
摘要： Molecularly oriented, thermoplastic elastomeric dental tapes extruded with a melt spinning extrusion carried out at draw ratios from between about 4:1 and about 7.5:1 and draw temperatures from between about 80° and 265° C. having: elongation at break of less than about 50%, an elastic limit of less than about 25% and enhanced tape flex-twist index from between about 2.5 and about 5, with the capacity to release substantive, flake-free, saliva soluble coatings during flossing.
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5.发明授权Blood-vessel endoscope system for storing a frozen picture in synchronization with heart pulsation 失效用于与心脏搏动同步地存储冻结图像的血管内窥镜系统
公开(公告)号：US4920413A
公开(公告)日：1990-04-24
申请号：US317247
申请日：1989-02-28
申请人： Ichiro Nakamura , Naruto Shinkai , David Barlow , Akio Nakada
发明人： Ichiro Nakamura , Naruto Shinkai , David Barlow , Akio Nakada
IPC分类号： A61B5/0452 , A61B1/04 , A61B5/0456 , H04N5/235
CPC分类号： A61B1/00039 , A61B1/0005 , A61B1/042 , A61B5/0456 , H04N5/2353 , A61B6/541
摘要： A blood-vessel endoscope system has an endoscope to be inserted into a blood vessel in a living body and a frozen-picture memorizing device connected to the endoscope, and is capable of storing a frozen picture when a release switch is actuated. The system is provided with a frozen-picture memorization controlling device so that a frozen picture free from a large blur may be stored in synchronization with the signal output from a heart pulsation measuring device for measuring the heart pulsation of the living body and at the timing that the action of a myocardium is reduced.
摘要翻译： 血管内窥镜系统具有插入生物体内的血管的内窥镜和与内窥镜连接的冷冻图像存储装置，并且能够在释放开关动作时存储冻结图像。 该系统设置有冻结图像存储控制装置，使得可以与从用于测量生物体的心脏脉动的心脏脉动测量装置输出的信号同步地存储没有大模糊的冻结图像，并且在定时 减轻心肌的作用。
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公开(公告)号：US20100175999A1
公开(公告)日：2010-07-15
申请号：US12523500
申请日：2008-01-16
申请人： David Barlow , David Thompson , Ken MacNamara , Stuart Polwart
发明人： David Barlow , David Thompson , Ken MacNamara , Stuart Polwart
CPC分类号： B32B27/06 , B01L3/502707 , B01L3/502738 , B01L2200/12 , B01L2300/0645 , B01L2300/0887 , B01L2300/123 , B01L2400/0638 , B32B27/32 , B32B2307/7265 , B32B2323/04 , B32B2323/10
摘要： The present invention relates to a microfluidic device, comprising a laminate of first and second films, one or each film including an integrally thermoformed structure such that the films together define an enclosed volume (19) for fluid containment therebetween, characterised in that each film itself comprises a laminate of a relatively higher softening temperature thermoplastic polymeric material (14,17) and with respect thereto, a relatively lower melt temperature thermoplastic polymeric material (15,16), the respective relatively low melt temperature thermoplastic polymeric materials of each film being melted together to attach the said first and second films together. The invention further relates to a method of manufacturing the microfluidic device.
摘要翻译： 微流体装置技术领域本发明涉及一种微流体装置，其包括第一和第二膜的层压体，一个或每个膜包括一体的热成型结构，使得膜一起限定用于其间流体容纳的封闭容积（19），其特征在于每个膜本身 包括相对较高的软化温度的热塑性聚合物材料（14,17）和相对于其相对较低的熔融温度的热塑性聚合物材料（15,16）的层压体，每个膜的各自相对较低的熔融温度的热塑性聚合材料被熔化 一起将所述第一和第二膜连接在一起。 本发明还涉及一种制造微流体装置的方法。
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公开(公告)号：US20100068477A1
公开(公告)日：2010-03-18
申请号：US12523496
申请日：2008-01-16
申请人： David Barlow
发明人： David Barlow
CPC分类号： B32B27/08 , B32B7/02 , B32B27/32 , B32B2307/31 , B32B2323/04 , B32B2323/10 , B32B2457/00 , Y10T428/24802 , Y10T428/24843 , Y10T428/24851 , Y10T428/24917 , Y10T428/24942 , Y10T428/249994 , Y10T428/269
摘要： The present invention relates to laminate comprising a first thermoplastic polymer layer with a first melt flow index, adjacent a thermoplastic polymer second layer with a second melt flow index, the first and second layer comprising the same thermoplastic polymer, characterised in that the first melt flow index is lower than the second melt flow index. The invention also relates to a microfluidic device comprising the laminate and a method for incorporating an ink pattern in the laminate.
摘要翻译： 本发明涉及包括具有第一熔体流动指数的第一热塑性聚合物层的层压体，邻近具有第二熔体流动指数的热塑性聚合物第二层，所述第一和第二层包含相同的热塑性聚合物，其特征在于，所述第一熔体流动 指数低于第二熔体流动指数。 本发明还涉及一种包括该层压体的微流体装置和一种将层叠体中的油墨图案结合的方法。
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公开(公告)号：US20080015409A1
公开(公告)日：2008-01-17
申请号：US11715166
申请日：2007-03-07
申请人： David Barlow , Kunihide Kaji , Takayuki Suzuki , Masatoshi Sato , Kensuke Hayashi , Takayasu Mikkaichi , Junji Shiono
发明人： David Barlow , Kunihide Kaji , Takayuki Suzuki , Masatoshi Sato , Kensuke Hayashi , Takayasu Mikkaichi , Junji Shiono
IPC分类号： A61B1/00
CPC分类号： A61B18/1492 , A61B2018/00559 , A61B2018/00601 , A61B2018/141 , A61B2018/1422 , A61B2018/144
摘要： This treatment device for endoscope is used for cutting body tissue while the treatment device is retractably projected from a catheter. The treatment device includes: a control wire inserted into the catheter; and a cutting electrode mounted at the distal end of the control wire with the cutting electrode being imparted a bent configuration in advance. The cutting electrode elastically deforms in a state where the cutting electrode is retracted into the catheter, thereby assuming such a shape as to resemble the configuration of the catheter.
摘要翻译： 该内窥镜用处理装置用于切割身体组织，同时治疗装置从导管缩回地突出。 治疗装置包括：插入导管中的控制线; 以及安装在控制线的远端的切割电极，切断电极预先赋予弯曲构造。 切割电极在切割电极缩回到导管中的状态下弹性变形，从而呈现与导管的形状相似的形状。
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9.发明申请Medical method and medical system conducted percutaneous or using naturally occurring body orifice 有权医疗方法和医疗系统进行经皮或使用自然发生的身体孔公开(公告)号：US20070255100A1
公开(公告)日：2007-11-01
申请号：US11650123
申请日：2007-01-05
IPC分类号： A61B1/00
CPC分类号： A61B1/041 , A61B1/0005 , A61B1/00101 , A61B1/00105 , A61B1/00135 , A61B1/00147 , A61B1/00158 , A61B1/00174 , A61B1/00183 , A61B1/00193 , A61B1/05 , A61B1/053 , A61B1/3132 , A61B90/361 , A61B2017/00283
摘要： A medical procedure and a system are provided so that two visions are obtainable through natural orifices by means of two observational apparatuses, or one the two visions is selectable. The medical procedure through a natural orifice comprises: forming an orifice in a hollow organ by using a device inserted into the hollow organ from a natural orifice of a patient; introducing a first observation device from said orifice formed in said hollow organ into an abdominal cavity; introducing a second observation device from said orifice formed in said hollow organ into the abdominal cavity; arranging said second observation device in a position different from that of said first observation device; simultaneously or selectively displaying an image obtained from said first observation device and an image obtained from said second observation device; and performing a desired procedure in the abdominal cavity while confirming the images.
摘要翻译： 提供医疗程序和系统，使得通过两个观察装置通过天然孔获得两个视觉，或者两个视觉可选择。 通过自然孔的医疗程序包括：通过使用从患者的天然孔插入中空器官的装置在中空器官中形成孔口; 将形成在所述中空器官内的所述孔的第一观察装置引入腹腔; 将形成在所述中空器官中的所述孔的第二观察装置引入腹腔; 将所述第二观察装置布置在与所述第一观察装置不同的位置; 同时或选择性地显示从所述第一观察装置获得的图像和从所述第二观察装置获得的图像; 并且在确认图像的同时在腹腔中执行所需的手术。
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公开(公告)号：US20070255165A1
公开(公告)日：2007-11-01
申请号：US11653145
申请日：2007-01-12
申请人： Takefumi Uesugi , Kenji Noda , Takayasu Mikkaichi , Kunihide Kaji , David Barlow
发明人： Takefumi Uesugi , Kenji Noda , Takayasu Mikkaichi , Kunihide Kaji , David Barlow
IPC分类号： A61M13/00
CPC分类号： A61B5/03 , A61B1/00135 , A61B1/015 , A61B2017/00278 , A61M13/003 , A61M2205/3331 , A61M2205/3344 , A61M2210/1021 , A61M2210/1053
摘要： In order to control the pressure in an abdominal cavity of a patient and a pressure in a hollow organ, a medical system includes: a first pressure sensor for measuring the pressure of a gas in the abdominal cavity; a first port for insufflating and evacuating the abdominal cavity; a second pressure sensor for measuring the pressure of a gas in the hollow organ; a second port for insufflating and evacuating the hollow organ; an air supply apparatus connected to the second port for controlling the air supply and evacuation based on the output by the first and second pressure sensors; a third port connected to the second pressure sensor in the air supply apparatus; an endoscope connected to the air supply apparatus; a pneumoperitoneum needle connected to the first port; and a puncture needle connected to the second port.
摘要翻译： 为了控制患者的腹腔内的压力和中空器官的压力，医疗系统包括：用于测量腹腔内气体压力的第一压力传感器; 第一个口腔，用于吸入和排空腹腔; 第二压力传感器，用于测量中空器官中的气体的压力; 第二个口腔，用于吹入和疏散空心器官; 连接到第二端口的空气供应装置，用于基于第一和第二压力传感器的输出来控制供气和排气; 连接到空气供应装置中的第二压力传感器的第三端口; 连接到空气供应装置的内窥镜; 连接到第一端口的气腹针; 以及连接到第二端口的穿刺针。
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