公开(公告)号：US08459260B2

公开(公告)日：2013-06-11

申请号：US13542331

申请日：2012-07-05

申请人： David John Bassin

发明人： David John Bassin

IPC分类号： F16K31/02

CPC分类号： A61M16/0057 ,  A61M16/0051 ,  A61M16/024 ,  A61M16/06 ,  A61M2016/0021 ,  A61M2016/003 ,  A61M2016/0036 ,  A61M2205/15 ,  A61M2205/16 ,  A61M2205/3331 ,  A61M2205/50

摘要： A respiratory treatment apparatus and method in which a leak is determined by using an averaging window. The window starts at the present time and extends back in time to a point determined according to a current one of progressively detected phase measures of a first respiratory cycle and a corresponding phase measure attributable to a preceding second respiratory cycle. In another aspect, a jamming index indicates whether the leak is rapidly changing. To the extent that jamming is high, the leak estimate used progressively changes from that using sliding breath-window averaging to a more robust and faster responding low-pass filter method, and adjustment of ventilatory support based on measures employing estimated respiratory flow is slowed down or stopped.

摘要翻译： 一种呼吸治疗装置和方法，其中通过使用平均窗来确定泄漏。 该窗口从当前开始，并且在时间上延伸到根据第一呼吸周期的逐渐检测的相位测量值和归因于之前的第二呼吸周期的相应相位测量值中的当前测量值确定的点。 另一方面，干扰指数指示泄漏是否迅速变化。 在干扰程度较大的情况下，泄漏估算值从使用滑动呼吸窗口平均值到更健壮，更快速响应的低通滤波方法逐渐变化，基于使用估计呼吸流量的措施调节呼吸支持减慢 或停止。

公开(公告)号：US08448640B2

公开(公告)日：2013-05-28

申请号：US13242752

申请日：2011-09-23

申请人： David John Bassin

发明人： David John Bassin

IPC分类号： A61M16/00

CPC分类号： A61M16/0069 ,  A61M16/00 ,  A61M16/0003 ,  A61M16/0066 ,  A61M16/024 ,  A61M16/04 ,  A61M16/06 ,  A61M16/0875 ,  A61M16/20 ,  A61M2205/3334 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2230/005 ,  A61M2230/40

摘要： A ventilator device delivers ventilatory support to a patient in a back up timed mode when patient respiration is not detected or a spontaneous mode when patient respiration is detected. The timing threshold governing the back-up mode is chosen to deviate from normal expected respiration time for the patient to promote patient initiated ventilation in the spontaneous mode but permit back-up ventilation in the event of apnea. Automated adjustments to the timing threshold during the timed mode are made from the less vigilant timing threshold to a more vigilant threshold at or near a timing of normal expected breathing of the patient. Such adjustments may be made from a minimum to a maximum vigilance timing settings or incrementally there between as a function of time in the timed mode which is preferably the number of delivered machine breaths.

公开(公告)号：US08356594B2

公开(公告)日：2013-01-22

申请号：US12613035

申请日：2009-11-05

申请人： Anthony John Ujhazy ,  Jonathan Caldwell Wright ,  Glenn Richards ,  David John Bassin ,  Michael Berthon-Jones

发明人： Anthony John Ujhazy ,  Jonathan Caldwell Wright ,  Glenn Richards ,  David John Bassin ,  Michael Berthon-Jones

IPC分类号： A62B9/00

CPC分类号： A61B5/4836 ,  A61B5/0826 ,  A61B5/087 ,  A61B5/7282 ,  A61B5/746 ,  A61M16/0051 ,  A61M16/0057 ,  A61M16/0066 ,  A61M16/0069 ,  A61M16/024 ,  A61M16/06 ,  A61M2016/0021 ,  A61M2016/0036 ,  A61M2205/3344 ,  A61M2230/005 ,  A61M2230/04 ,  A61M2230/10 ,  A61M2230/18 ,  A61M2230/40 ,  A61M2230/435 ,  A61M2230/63

摘要： Methods and apparatus for assessing the condition of and treating patients for heart failure by the delivery of continuous positive airway pressure are disclosed. Treatment of obstruction due to reflex vocal cord closure often experienced by heart failure patients is distinguished from treatment of upper airway obstruction typically associated with Obstructive Sleep Disorder Treatment may also be implemented by delivering synchronized cardiac pressure oscillations superimposed on a respiratory pressure level to provide assistance for the heart. Heart treatment pressure dose indicator may be calculated for prescribing and monitoring the delivery of treatment. The apparatus may also generate data to track heart failure condition that may be indicative of the degree of severity of heart failure based upon breathing patterns to assist in the diagnosis and management of heart failure patients.

摘要翻译： 公开了通过递送持续气道正压通气来评估患者心力衰竭状况和治疗方法和装置。 治疗由于心力衰竭患者经常发生的反射性声带闭合引起的阻塞与区别于通常与阻塞性睡眠障碍相关的上呼吸道阻塞治疗也可以通过递送叠加在呼吸压力水平上的同步心脏压力振荡来实现，以便为 心脏 可以计算心脏治疗压力剂量指标，用于处方和监测治疗的递送。 该装置还可以生成跟踪心力衰竭状况的数据，该状况可以基于呼吸模式来指示心力衰竭的严重程度，以帮助心力衰竭患者的诊断和管理。

公开(公告)号：US20120145153A1

公开(公告)日：2012-06-14

申请号：US13383320

申请日：2010-04-07

申请人： David John Bassin ,  Glenn Richards

发明人： David John Bassin ,  Glenn Richards

IPC分类号： A61M16/00

CPC分类号： A61M16/0069 ,  A61M16/024 ,  A61M2016/0021 ,  A61M2016/0027 ,  A61M2205/505

摘要： A respiratory treatment apparatus implements pressure delivery control settings by improved set-up procedures. In such an embodiment, a processor may automate setting of parameters for delivering a controlled flow of breathable gas. Data sets of pressure delivery parameter settings may be associated with one or more respiratory pathology indicators. The respiratory pathology indicators may each represent a different respiratory condition diagnosis. The processor may then prompt for an input of at least one of the respiratory pathology indicators. In response to the input, a particular set of pressure delivery parameter settings associated with the input respiratory pathology indicator may then serve as a basis for setting controls for delivering a controlled flow of breathable gas for respiratory treatment.

摘要翻译： 呼吸治疗设备通过改进的设置程序实现压力传递控制设置。 在这样的实施例中，处理器可以自动设置用于传送可控气流的可呼吸气体的参数。 压力递送参数设置的数据集可以与一个或多个呼吸道病理学指标相关联。 呼吸道病理学指标可能代表不同的呼吸系统诊断。 处理器然后可以提示输入至少一个呼吸病理指示符。 响应于输入，与输入的呼吸道病理学指示符相关联的特定的一组压力递送参数设置然后可以用作设置用于递送用于呼吸治疗的受控流动的可呼吸气体的控制的基础。

公开(公告)号：US20120012110A1

公开(公告)日：2012-01-19

申请号：US13242752

申请日：2011-09-23

申请人： David John BASSIN

发明人： David John BASSIN

IPC分类号： A61M16/00

CPC分类号： A61M16/0069 ,  A61M16/00 ,  A61M16/0003 ,  A61M16/0066 ,  A61M16/024 ,  A61M16/04 ,  A61M16/06 ,  A61M16/0875 ,  A61M16/20 ,  A61M2205/3334 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2230/005 ,  A61M2230/40

摘要： A ventilator device delivers ventilatory support to a patient in a back up timed mode when patient respiration is not detected or a spontaneous mode when patient respiration is detected. The timing threshold governing the back-up mode is chosen to deviate from normal expected respiration time for the patient to promote patient initiated ventilation in the spontaneous mode but permit back-up ventilation in the event of apnea. Automated adjustments to the timing threshold during the timed mode are made from the less vigilant timing threshold to a more vigilant threshold at or near a timing of normal expected breathing of the patient. Such adjustments may be made from a minimum to a maximum vigilance timing settings or incrementally there between as a function of time in the timed mode which is preferably the number of delivered machine breaths.

摘要翻译： 呼吸机设备在没有检测到患者呼吸时，以后备时间模式向患者提供通气支持，或者当检测到患者呼吸时，自发模式。 选择控制备用模式的时间阈值以偏离正常的预期呼吸时间，以使患者以自发模式促进患者发起的通气，但是在呼吸暂停的情况下允许备用通气。 在定时模式期间对定时阈值的自动调整是从患者的正常预期呼吸时刻或接近正常预期呼吸时间的警戒时间阈值变为更警惕的阈值。 这样的调整可以从定时模式中的最小警告时间设置到最大警戒时间设置或其间的时间间隔作为时间的函数，其优选地是传送的机器呼吸次数。

公开(公告)号：US20110203588A1

公开(公告)日：2011-08-25

申请号：US12599715

申请日：2009-05-09

申请人： Jeffrey Peter Armitstead ,  Peter Edward Bateman ,  David John Bassin

发明人： Jeffrey Peter Armitstead ,  Peter Edward Bateman ,  David John Bassin

IPC分类号： A61M16/00

摘要： A respiratory flow limitation detection device, which can include an airway pressure treatment generator, determines a flow limitation measure (506) based one or more shape indices for detecting partial obstruction and a measure of a patient's ventilation or respiratory duty cycle. The shape indices may be based on function(s) that ascertain the likelihood of the presence of M-shaped breathing patterns and/or chair-shaped breathing patterns. The measure of ventilation may be based on analysis of current and prior tidal volumes to detect a less than normal patient ventilation. The duty cycle measure may be a ratio of current and prior measures of inspiratory time to respiratory cycle time to detect an increase in the patient's inspiratory cycle time relative to the respiratory cycle time. A pressure setting based on the flow limitation may then be used to adjust the treatment pressure to ameliorate the patient's detected flow limitation condition.

摘要翻译： 可以包括气道压力治疗发生器的呼吸流量限制检测装置基于用于检测部分阻塞的一个或多个形状指数和患者的通气或呼吸占空比的测量来确定流量限制测量（506）。 形状指数可以基于确定存在M形呼吸模式和/或椅形呼吸模式的可能性的功能。 通气量可以基于当前和以前潮气量的分析，以检测不到一般的患者通气。 占空比测量可以是当前和先前测量吸气时间与呼吸周期时间之间的比例，以检测患者吸气循环时间相对于呼吸周期时间的增加。 然后可以使用基于流量限制的压力设置来调节治疗压力以改善患者检测到的流量限制条件。

公开(公告)号：US07866318B2

公开(公告)日：2011-01-11

申请号：US10596813

申请日：2005-01-07

申请人： David John Bassin

发明人： David John Bassin

IPC分类号： A61M16/00

CPC分类号： A61B5/4818 ,  A61B5/087 ,  A61B5/725 ,  A61B5/7264 ,  A61B5/7282 ,  A61M16/00 ,  A61M16/0003 ,  A61M16/0069 ,  A61M16/024 ,  A61M16/06 ,  A61M2016/0024 ,  A61M2016/0042

摘要： A method of operating a CPAP apparatus in which the interface pressure is controlled to rapidly drop at the start of expiration by an expiratory relief pressure (ERP) that is independent of instantaneous respiratory flow, following which the pressure rises to an inspiratory level at or shortly before the end of expiration, or at the onset of an expiratory pause, if any. The ERP is an increasing function of the inspiratory pressure. The expiratory pressure follows a template that is a function of the expected expiration time, the magnitude of the template being equal to the ERP. The current estimated proportion of expiration is determined by comparing the expiration time of the breath in progress to low-pass filtered expiratory durations measured for a number of the preceding breaths.

摘要翻译： 一种操作CPAP装置的方法，其中接口压力被控制以在呼气开始时迅速地通过不依赖于瞬时呼吸流量的呼气释放压力（ERP）而下降，随后压力在或短时间内升至吸气水平 在呼气结束之前，或在呼气暂停开始时（如果有的话）。 ERP是吸气压力越来越大的功能。 呼气压力遵循模板，该模板是预期到期时间的函数，模板的大小等于ERP。 当前估计的呼气比例是通过将进行中的呼吸的呼气时间与对前一次呼吸数量测量的低通过滤呼气持续时间进行比较而确定的。

公开(公告)号：US20100275921A1

公开(公告)日：2010-11-04

申请号：US12751174

申请日：2010-03-31

申请人： Klaus Henry Schindhelm ,  David John Bassin ,  Glenn Richards

发明人： Klaus Henry Schindhelm ,  David John Bassin ,  Glenn Richards

IPC分类号： A61M16/00 ,  A61B5/085 ,  G08B23/00

CPC分类号： A61M16/0051 ,  A61B5/08 ,  A61B5/7264 ,  A61B5/7275 ,  A61M16/0006 ,  A61M16/0069 ,  A61M16/026 ,  A61M2016/0027 ,  A61M2016/0036 ,  A61M2205/3375 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/502 ,  A61M2230/04 ,  A61M2230/205 ,  A61M2230/42 ,  A61M2230/46 ,  G06F19/00

摘要： Devices and systems provide methods of detecting a severity change in respiratory insufficiency (RI) or chronic obstructive pulmonary disease (COPD) condition of a patient. In an example embodiment, a detection monitoring device determines one or more severity change indicators based on a measure of supplied pressure or other representative measure determined by the device. The supplied pressure may optionally be determined during pressure treatment that satisfies a target ventilation. The supplied pressure or representative data may be compared to one or more thresholds that are selected to represent a change in the condition of the RI or COPD patient such as an exacerbation of a prior condition. Results of the comparisons may trigger one or more warnings or messages to notify a patient or physician of a pending change to the patient's RI or COPD condition so that the patient may more immediately seek medical attention to treat the condition.

摘要翻译： 装置和系统提供了检测患者呼吸功能不全（RI）或慢性阻塞性肺病（COPD）病情严重程度变化的方法。 在示例实施例中，检测监控设备基于由设备确定的所提供的压力或其他代表性度量的度量来确定一个或多个严重性变化指示符。 所提供的压力可以任选地在满足目标通气的压力处理期间确定。 提供的压力或代表性数据可以与被选择以表示RI或COPD患者的状况的变化的一个或多个阈值进行比较，例如先前病症的恶化。 比较结果可能会触发一个或多个警告或消息，通知患者或医师对患者的RI或COPD状况的待决变更，以便患者可以更加立即寻求医疗护理来治疗病情。

公开(公告)号：US20100236556A1

公开(公告)日：2010-09-23

申请号：US12765380

申请日：2010-04-22

申请人： Paul Anthony Green ,  David John Bassin

发明人： Paul Anthony Green ,  David John Bassin

IPC分类号： A61M16/00

CPC分类号： A61M16/0069 ,  A61M16/024 ,  A61M2016/0027 ,  A61M2016/0039 ,  A61M2230/04

摘要： A method and apparatus that provides an expert system for determining respiratory phase during ventilatory support of a subject. Discrete phase states are partitioned and prior probability functions and observed probability functions for each state are defined. The probability functions are based upon relative duration of each state as well as the flow characteristics of each state. These functions are combined to determine phase probabilities for each state using Bayes' theorem. The calculated probabilities for the states may then be compared to determine which state the subject is experiencing. A ventilator may then conform respiratory support in accordance with the most probable phase. To provide a learning feature, the probability functions may be adjusted during use to provide a more subject specific response that accounts for changing respiratory characteristics.

摘要翻译： 一种提供用于在受试者的通气支持期间确定呼吸相位的专家系统的方法和装置。 离散相位状态被划分，并且定义了每个状态的先验概率函数和观测概率函数。 概率函数基于每个状态的相对持续时间以及每个状态的流量特性。 这些功能被组合以使用贝叶斯定理确定每个状态的相位概率。 然后可以比较所计算的状态概率，以确定受试者正在经历的状态。 然后呼吸机可以根据最可能的阶段来符合呼吸支持。 为了提供学习特征，在使用期间可以调整概率函数以提供考虑到呼吸特征变化的更多受试者特异性响应。

公开(公告)号：US20100018531A1

公开(公告)日：2010-01-28

申请号：US12573382

申请日：2009-10-05

申请人： David John BASSIN

发明人： David John BASSIN

IPC分类号： A61M16/00

CPC分类号： A61M16/0069 ,  A61M16/00 ,  A61M16/0003 ,  A61M16/0066 ,  A61M16/024 ,  A61M16/04 ,  A61M16/06 ,  A61M16/0875 ,  A61M16/20 ,  A61M2205/3334 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2230/005 ,  A61M2230/40

摘要： A ventilator device delivers ventilatory support to a patient in a back up timed mode when patient respiration is not detected or a spontaneous mode when patient respiration is detected. The timing threshold governing the back-up mode is chosen to deviate from normal expected respiration time for the patient to promote patient initiated ventilation in the spontaneous mode but permit back-up ventilation in the event of apnea. Automated adjustments to the timing threshold during the timed mode are made from the less vigilant timing threshold to a more vigilant threshold at or near a timing of normal expected breathing of the patient. Such adjustments may be made from a minimum to a maximum vigilance timing settings or incrementally there between as a function of time in the timed mode which is preferably the number of delivered machine breaths.

摘要翻译： 呼吸机设备在没有检测到患者呼吸时，以后备时间模式向患者提供通气支持，或者当检测到患者呼吸时，自发模式。 控制后备模式的时间阈值被选择为偏离正常的预期呼吸时间，以使患者以自发模式促进患者发起的通气，但是在呼吸暂停的情况下允许备用通气。 在定时模式期间对定时阈值的自动调整是从患者的正常预期呼吸时刻或接近正常预期呼吸时间的警戒时间阈值变为更警惕的阈值。 这样的调整可以从定时模式中的最小警告时间设置到最大警戒时间设置或其间的时间间隔作为时间的函数，其优选地是传送的机器呼吸次数。