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公开(公告)号：US09174923B2
公开(公告)日：2015-11-03
申请号：US12349329
申请日：2009-01-06
CPC分类号： C07C69/68 , A61K31/22 , B01F1/00 , B01F17/0021 , C07C67/31
摘要： Alkyl lactyllactate and alkoxylated alkyl lactyllactate compounds that are useful as solvents in a variety of applications are disclosed. The compounds are derived from a hydroxyl containing compound and a lactide or lactic acid source that has a specific chirality. The alkyl lactyllactate and alkoxylated alkyl lactyllactate compounds are particularly suitable for use as solvents in applications requiring cold tolerance performance without inclusion of additional volatile components.
摘要翻译： 公开了在各种应用中可用作溶剂的乳酸乳链烷酯和烷氧基化烷基乳糖基化合物。 化合物衍生自具有特定手性的含羟基化合物和丙交酯或乳酸源。 乳酸乳酸烷基酯和烷氧基化烷基乳糖乳酸酯化合物特别适合用作需要耐寒性能的应用中的溶剂，而不包含额外的挥发性组分。
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公开(公告)号：US08642528B2
公开(公告)日：2014-02-04
申请号：US12349316
申请日：2009-01-06
申请人： David R Allen , Anatoliy A. Dameshek , Branko Sajic , Irene Shapiro , Xue Min Dong , Christopher D Smith , Jacqueline M Pytel , Jeremy Weitgenant
发明人： David R Allen , Anatoliy A. Dameshek , Branko Sajic , Irene Shapiro , Xue Min Dong , Christopher D Smith , Jacqueline M Pytel , Jeremy Weitgenant
IPC分类号： C11D17/00
CPC分类号： C07C67/08 , A61K8/37 , A61Q5/02 , A61Q15/00 , A61Q19/10 , C07B2200/07 , C07C67/03 , C07C69/68
摘要： Provided are alkyl lactyllactate compositions that can be prepared from (1) lactide or alternatively lactic acid, and (2) a hydroxyl containing compound such as an alcohol, preferably a fatty alcohol or an alkoxylated alcohol, with (3) an acid catalyst. Preferably, the fatty alcohol contains from about 6 to 18 carbon atoms, such as lauryl alcohol. The alkyl lactyllactates can be used as surfactants, emulsifiers, skin feel agents, film formers, thickeners, rheological modifiers, etc., for personal care and other application areas. Compositions containing at least one alkyl lactyllactate are also provided. The compositions can further contain at least one surfactant.
摘要翻译： 本发明提供可由（1）丙交酯或乳酸制备的乳酸乳糖酯组合物，和（2）含羟基化合物如醇，优选脂肪醇或烷氧基化醇与（3）酸催化剂。 优选地，脂肪醇含有约6至18个碳原子，例如月桂醇。 乳酸乳酸烷基酯可用作个人护理和其他应用领域的表面活性剂，乳化剂，皮肤感觉剂，成膜剂，增稠剂，流变改性剂等。 还提供了含有至少一种乳糖基乳酸酯的组合物。 组合物还可以含有至少一种表面活性剂。
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公开(公告)号：US20090200511A1
公开(公告)日：2009-08-13
申请号：US12349316
申请日：2009-01-06
申请人： David R. Allen , Anatoliy A. Dameshek , Branko Sajic , Irene Shapiro , Xue Min Dong , Christopher D. Smith , Jacqueline M. Pytel , Jeremy Weitgenant
发明人： David R. Allen , Anatoliy A. Dameshek , Branko Sajic , Irene Shapiro , Xue Min Dong , Christopher D. Smith , Jacqueline M. Pytel , Jeremy Weitgenant
CPC分类号： C07C67/08 , A61K8/37 , A61Q5/02 , A61Q15/00 , A61Q19/10 , C07B2200/07 , C07C67/03 , C07C69/68
摘要： Provided are alkyl lactyllactate compositions that can be prepared from (1) lactide or alternatively lactic acid, and (2) a hydroxyl containing compound such as an alcohol, preferably a fatty alcohol or an alkoxylated alcohol, with (3) an acid catalyst. Preferably, the fatty alcohol contains from about 6 to 18 carbon atoms, such as lauryl alcohol. The alkyl lactyllactates can be used as surfactants, emulsifiers, skin feel agents, film formers, thickeners, rheological modifiers, etc., for personal care and other application areas. Compositions containing at least one alkyl lactyllactate are also provided. The compositions can further contain at least one surfactant.
摘要翻译： 本发明提供可由（1）丙交酯或乳酸制备的乳酸乳糖酯组合物，和（2）含羟基化合物如醇，优选脂肪醇或烷氧基化醇与（3）酸催化剂。 优选地，脂肪醇含有约6至18个碳原子，例如月桂醇。 乳酸乳酸烷基酯可用作个人护理和其他应用领域的表面活性剂，乳化剂，皮肤感觉剂，成膜剂，增稠剂，流变改性剂等。 还提供了含有至少一种乳糖基乳酸酯的组合物。 组合物还可以含有至少一种表面活性剂。
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公开(公告)号：US20090173917A1
公开(公告)日：2009-07-09
申请号：US12349329
申请日：2009-01-06
CPC分类号： C07C69/68 , A61K31/22 , B01F1/00 , B01F17/0021 , C07C67/31
摘要： Alkyl lactyllactate and alkoxylated alkyl lactyllactate compounds that are useful as solvents in a variety of applications are disclosed. The compounds are derived from a hydroxyl containing compound and a lactide or lactic acid source that has a specific chirality. The alkyl lactyllactate and alkoxylated alkyl lactyllactate compounds are particularly suitable for use as solvents in applications requiring cold tolerance performance without inclusion of additional volatile components.
摘要翻译： 公开了在各种应用中可用作溶剂的乳酸乳链烷酯和烷氧基化烷基乳糖基化合物。 化合物衍生自具有特定手性的含羟基化合物和丙交酯或乳酸源。 乳酸乳酸烷基酯和烷氧基化烷基乳糖乳酸酯化合物特别适合用作需要耐寒性能的应用中的溶剂，而不包含额外的挥发性组分。
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公开(公告)号：US4932197A
公开(公告)日：1990-06-12
申请号：US291277
申请日：1988-12-28
申请人： David R. Allen
发明人： David R. Allen
IPC分类号： A01D78/00
CPC分类号： A01D78/146 , A01D78/001
摘要： An apparatus having a frame adapted for earth traversing movement in a direction of travel and having portions laterally positionable with respect to the direction of travel, a work implement pivotally mounted on the laterally positionable portion of the frame for motion therewith relative to a predetermined axis through a range of selected operative positions, and a device for securing the work implement relative to the predetermined axis in a selected one of the operative positions for operation during movement of the frame along the path of travel.
摘要翻译： 一种具有框架的装置，其适于在行进方向上的接地横移运动并且具有相对于行进方向可横向定位的部分;工作装置，枢转地安装在框架的可横向定位的部分上，以相对于预定轴线通过 所选择的操作位置的范围，以及用于在所选择的一个操作位置中相对于预定轴线固定工作工具的装置，用于在沿着行进路径移动框架期间操作。
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公开(公告)号：US6050018A
公开(公告)日：2000-04-18
申请号：US241844
申请日：1999-02-01
申请人： David R. Allen
发明人： David R. Allen
摘要： A rig for bait casting sandshrimp tails, and method for using the rig. A fish hook is attached to a forward end of fishing line leader. The forward end of a longitudinally elongated bait threader is attached to a rear end of the leader. A buoyant, bowling-pin-shaped, bobber is slidably mounted on the leader between the hook and threader. The rear end of the threader is pointed. In use, the pointed end of the threader is inserted longitudinally through a sandshrimp tail. The tail is moved forward over and past the threader, thence forward along the leader and onto the bobber so as to substantially enclose and surround the bobber. The rear end of the threader is then attached to a double swivel that is coupled to a weight and a fishing line.
摘要翻译： 用于饵料砂虾尾料的钻机，以及使用钻机的方法。 钓鱼线的前端附有鱼钩。 纵向伸长的诱饵穿线器的前端连接到引导件的后端。 一个漂浮的保龄球形的浮子可滑动地安装在钩和穿线器之间的引导件上。 穿线器的后端是尖的。 在使用中，穿线器的尖端纵向插入砂虾尾。 尾巴向前移动并越过穿线器，然后沿着引导件前进到浮子上，以便基本上包围并围绕浮子。 然后将穿线器的后端连接到耦合到重物和钓鱼线的双重旋转件。
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公开(公告)号：US4343142A
公开(公告)日：1982-08-10
申请号：US144610
申请日：1980-04-28
申请人： David R. Allen
发明人： David R. Allen
CPC分类号： A01D67/00 , A01D78/006 , Y10S56/11
摘要： An apparatus having a frame adapted for earth traversing movement in a direction of travel and having a portion laterally positionable with respect to the direction of travel, a work assembly pivotally mounted on the laterally positionable portion of the frame for movement therewith, and an arm interconnecting the work assembly and the frame to pivot the work assembly through a plurality of positions relative to the direction of travel as the portion of the frame is laterally positioned.
摘要翻译： 一种装置，其具有适于在行进方向上的接地横移运动并具有相对于行进方向横向定位的部分的框架;工作组件，其枢转地安装在框架的可横向定位的部分上以与其一起运动;以及臂互连 工作组件和框架，用于当框架的一部分横向定位时，使工作组件相对于行进方向通过多个位置枢转。
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公开(公告)号：US20130281688A1
公开(公告)日：2013-10-24
申请号：US13867542
申请日：2013-04-22
IPC分类号： C07H1/00 , C07C41/06 , C07F9/09 , C07C41/03 , C07C67/08 , C07C43/178 , C07C69/007
CPC分类号： C07C29/147 , C07C29/095 , C07C29/74 , C07C41/03 , C07C41/06 , C07C43/178 , C07C67/08 , C07C69/007 , C07F9/09 , C07H1/00 , C08F210/00 , C08F216/04 , C07C33/025
摘要： Unsaturated alcohol compositions are obtained by reducing a metathesis-derived hydrocarbyl unsaturated ester. Also disclosed is a process for preparing an unsaturated alcohol composition, where a metathesis derived hydrocarbyl carbonyl compound is reacted in the presence of a silane compound, an organic solvent, and a catalyst system prepared from a metallic complex and a reducing agent. This mixture is then hydrolyzed with a metallic base, and then mixed with organic solvent. The resultant mixture is then separated, washed, dried, and/or purified to produce the unsaturated alcohol composition. The unsaturated alcohol derivatives are useful in many end-use applications, including, for example, lubricants, functional fluids, fuels, functional additives for such lubricants, functional fluids and fuels, plasticizers, asphalt additives, friction reducing agents, plastics, and adhesives.
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公开(公告)号：US08093231B2
公开(公告)日：2012-01-10
申请号：US11779234
申请日：2007-07-17
申请人： David R. Allen , Wenli Ma , Brian T. Peterson , Louise Robinson , Steven R. Schow , Songyuan Shi , Reyna J. Simon , Kevin T. Weber , Michael M. Wick
发明人： David R. Allen , Wenli Ma , Brian T. Peterson , Louise Robinson , Steven R. Schow , Songyuan Shi , Reyna J. Simon , Kevin T. Weber , Michael M. Wick
CPC分类号： C07F9/2458 , C07F9/2408 , C07F9/572 , C07F9/58 , C07F9/59 , C07F9/650952 , C07F9/6533 , C07F9/65515 , C07F9/655345 , C07F9/65616
摘要： Sulfonylethyl and thioethyl phosphorodiamidates, their preparation and intermediates in their preparation, formulations containing them, and their pharmaceutical use. The compounds are useful for treating cancer, alone and in combination with other anticancer therapies.
摘要翻译： 磺基乙基和硫代乙基磷酰二胺，它们的制备和中间体在制备中，含有它们的制剂及其药物用途。 该化合物可用于单独治疗和与其它抗癌疗法组合治疗癌症。
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10.发明授权
公开(公告)号：US5587481A
公开(公告)日：1996-12-24
申请号：US603744
申请日：1996-02-20
申请人： David R. Allen , Scott Jenkins , Loraine Klein , Robert Erickson , Diane Froen
发明人： David R. Allen , Scott Jenkins , Loraine Klein , Robert Erickson , Diane Froen
IPC分类号： A61K31/472 , A61P31/14 , A61P31/18 , C07D217/26 , C07D217/16
CPC分类号： C07D217/26
摘要： Methods for preparing (S)-N-tert-butyl-1,2,3,4-tetrahydro-3-isoquinoline-carboxamide ("tic-c"), and converting tic-c to (S)-decahydroisoquinoline-3-carboxylic acid t-butylamide ("tic-d") are disclosed. The initial step in the formation of tic-c involves the phosgenation of a substituted tetrahydroisoquinoline to form an N-carboxy anhydride. Tic-d is used as an intermediate in the synthesis of known compounds having pharmaceutical activity.
摘要翻译： 制备（S）-N-叔丁基-1,2,3,4-四氢-3-异喹啉 - 甲酰胺（“tic-c”）的方法，将tic-c转化为（S） - 十氢异喹啉-3- 羧酸叔丁基酰胺（“tic-d”）。 形成tic-c的初始步骤涉及取代的四氢异喹啉的光气化形成N-羧酸酐。 Tic-d用作合成具有药物活性的已知化合物的中间体。
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