NON-CONTACT SPATIAL SUPER-RESOLUTION COHERENT RAMAN SPECTROMETRIC IMAGING METHOD

    公开(公告)号:US20220155233A1

    公开(公告)日:2022-05-19

    申请号:US17528271

    申请日:2021-11-17

    Abstract: A Raman spectrometric imaging method, including: placing a sample on a two-dimensional translation stage; emitting a first light beam by a first optical comb light source; dividing the first light beam into a pump light beam and a depletion light beam to illuminate the sample; guiding the pump light beam to illuminate a region of the sample to excite molecules of the sample in the region; guiding the depletion light beam to the region of the sample to make excited molecules at a periphery of the region to return into a vibrational ground state; emitting a second light beam as a probe light beam by a second optical comb light source to the remaining excited molecules to generate a CARS signal; recording the CARS signal for imaging; moving the two-dimensional translation stage to scan other regions of the sample to form an image of the sample.

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