公开(公告)号：US06171241B2

公开(公告)日：2001-01-09

申请号：US09095910

申请日：1998-06-11

申请人： Elliot R. McVeigh ,  Bradley D. Bolster, Jr.

发明人： Elliot R. McVeigh ,  Bradley D. Bolster, Jr.

IPC分类号： A61B5055

CPC分类号： A61B5/1128 ,  A61B5/055 ,  A61B5/7257 ,  G01R33/563 ,  G01R33/56333 ,  G01R33/5673

摘要： A method of magnetic resonance imaging of myocardial motion includes positioning a portion of a patient such as a patient's heart within a main magnetic field and employing a plurality of RF signals to establish a plurality of parallel plane tags through the portion. In imaging heart motion, a first minimum spacing between adjacent tags is employed in a region where the tags will decrease their separation over systole and a second initial tag separation will be employed for portions wherein the tags increase their separation over systole. The method facilitates simultaneous imaging of both such motions. Fourier coefficients may be employed in establishing the generally parallel tags which may be positioned generally symmetrically about a central tag.

摘要翻译： 心肌运动的磁共振成像的方法包括将病人心脏的一部分患者定位在主磁场内，并采用多个RF信号，以通过该部分建立多个平行平面标签。 在成像心脏运动中，相邻标签之间的第一最小间距用于标签将减小其在收缩期上的分离的区域，并且第二初始标签分离将用于其中标签增加其与收缩期分离的部分。 该方法有助于同时成像这两种运动。 可以采用傅里叶系数来建立大致平行的标签，其可以围绕中心标签大致对称地定位。

公开(公告)号：US08068893B2

公开(公告)日：2011-11-29

申请号：US10076882

申请日：2002-02-14

申请人： Michael Guttman ,  Elliot R. McVeigh

发明人： Michael Guttman ,  Elliot R. McVeigh

IPC分类号： A61B5/05

CPC分类号： G06T15/08 ,  G01R33/5608 ,  G01R33/56308

摘要： A method of producing volume renderings from magnetic resonance image data in real time with user interactivity. The method comprises collecting raw magnetic resonance image (MRI) data representative of shapes within an image volume; transferring the raw MRI data to a computer; and continuously producing volume renderings from the raw MRI data in real time with respect to the act of collecting raw MRI data representative of shapes within the image volume.

摘要翻译： 一种利用用户交互性实时地从磁共振图像数据产生体积渲染的方法。 该方法包括收集表示图像体积内的形状的原始磁共振图像（MRI）数据; 将原始MRI数据传输到计算机; 并且相对于收集表示图像体积内的形状的原始MRI数据的动作，实时地从原始MRI数据生成体积效果图。

公开(公告)号：US07822460B2

公开(公告)日：2010-10-26

申请号：US11924877

申请日：2007-10-26

申请人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

发明人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

IPC分类号： A61B5/05 ,  G01V3/00

CPC分类号： A61B5/055 ,  A61B5/415 ,  A61B5/418 ,  A61B18/1492 ,  A61B90/36 ,  A61B2017/00039 ,  A61B2017/00053 ,  A61B2090/374 ,  G01R33/285 ,  G01R33/34084 ,  G01R33/4808 ,  G01R33/5601

摘要： A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention further provides a system for eliminating the pickup of RF energy in which intracardiac wires are detuned by filtering so that they become very inefficient antennas. An RF filtering system is provided for suppressing the MR imaging signal while not attenuating the RF ablative current. Steering means may be provided for steering the invasive catheter under MR guidance.

摘要翻译： 公开了一种使用磁共振成像来提高电生理过程精度的系统和方法。 该系统在其优选实施例中提供了一种侵入性组合电生理学和成像天线导管，其包括用于接收磁共振信号的RF天线和用于接收电位的诊断电极。 组合的电生理和成像天线导管与磁共振成像扫描仪结合使用以在电生理诊断或治疗过程中引导和提供可视化。 本发明还提供一种用于消除射频能量的拾取的系统，其中心内线通过滤波失谐，使得它们变得非常低效的天线。 提供RF滤波系统，用于抑制MR成像信号，同时不衰减RF消融电流。 可以提供转向装置用于在MR引导下转导侵入性导管。

公开(公告)号：US07412276B2

公开(公告)日：2008-08-12

申请号：US10791622

申请日：2004-03-02

申请人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert C. Lardo ,  Hugh Calkins ,  Joao Lima

发明人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert C. Lardo ,  Hugh Calkins ,  Joao Lima

IPC分类号： A61B5/05

CPC分类号： A61B5/055 ,  A61B5/415 ,  A61B5/418 ,  A61B18/1492 ,  A61B90/36 ,  A61B2017/00039 ,  A61B2017/00053 ,  A61B2090/374 ,  G01R33/285 ,  G01R33/34084 ,  G01R33/4808 ,  G01R33/5601

摘要： A method of performing brain therapy may include placing a subject in a main magnetic field, introducing into the subject's brain a combination imaging and therapeutic probe, the probe including a magnetic resonance imaging antenna and an electrical energy application element, acquiring a first magnetic resonance image from the antenna of the combination probe, acquiring a second magnetic resonance image from a surface coil, combining the first and second magnetic resonance images to produce a composite image, positioning the combination probe within the brain with guidance from at least one of the images, and delivering electrical energy to the brain from the electrical energy application element of the combination probe thus positioned.

摘要翻译： 执行脑部治疗的方法可以包括将受试者放置在主磁场中，将主体脑中的组合成像和治疗探针引入，所述探针包括磁共振成像天线和电能应用元件，获取第一磁共振图像 从组合探针的天线，从表面线圈获取第二磁共振图像，组合第一和第二磁共振图像以产生合成图像，通过来自至少一个图像的引导将组合探针定位在脑内， 以及从如此定位的组合探针的电能施加元件向大脑递送电能。

公开(公告)号：US06701176B1

公开(公告)日：2004-03-02

申请号：US09428990

申请日：1999-10-29

申请人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

发明人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

IPC分类号： A61B5055

CPC分类号： A61B5/055 ,  A61B5/415 ,  A61B5/418 ,  A61B18/1492 ,  A61B90/36 ,  A61B2017/00039 ,  A61B2017/00053 ,  A61B2090/374 ,  G01R33/285 ,  G01R33/34084 ,  G01R33/4808 ,  G01R33/5601

摘要： A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention is particularly applicable to catheter ablation, e.g., ablation of atrial fibrillation. In embodiments which are useful for catheter ablation, the combined electrophysiology and imaging antenna catheter may further include an ablation tip, and such embodiment may be used as an intracardiac device to both deliver energy to selected areas of tissue and visualize the resulting ablation lesions, thereby greatly simplifying production of continuous linear lesions. The invention further includes embodiments useful for guiding electrophysiologic diagnostic and therapeutic procedures other than ablation. Imaging of ablation lesions may be further enhanced by use of MR contrast agents. The antenna utilized in the combined electrophysiology and imaging catheter for receiving MR signals is preferably of the coaxial or “loopless” type. High-resolution images from the antenna may be combined with low-resolution images from surface coils of the MR scanner to produce a composite image. The invention further provides a system for eliminating the pickup of RF energy in which intracardiac wires are detuned by filtering so that they become very inefficient antennas. An RF filtering system is provided for suppressing the MR imaging signal while not attenuating the RF ablative current. Steering means may be provided for steering the invasive catheter under MR guidance. Other ablative methods can be used such as laser, ultrasound, and low temperatures.

公开(公告)号：US20120253169A1

公开(公告)日：2012-10-04

申请号：US13305496

申请日：2011-11-28

申请人： Michael Guttman ,  Elliot R. McVeigh

发明人： Michael Guttman ,  Elliot R. McVeigh

IPC分类号： A61B5/055

CPC分类号： G06T15/08 ,  G01R33/5608 ,  G01R33/56308

摘要： A method of producing volume renderings from magnetic resonance image data in real time with user interactivity. The method comprises collecting raw magnetic resonance image (MRI) data representative of shapes within an image volume; transferring the raw MRI data to a computer; and continuously producing volume renderings from the raw MRI data in real time with respect to the act of collecting raw MRI data representative of shapes within the image volume.

摘要翻译： 一种利用用户交互性实时地从磁共振图像数据产生体积渲染的方法。 该方法包括收集表示图像体积内的形状的原始磁共振图像（MRI）数据; 将原始MRI数据传输到计算机; 并且相对于收集表示图像体积内的形状的原始MRI数据的动作，实时地从原始MRI数据生成体积效果图。

公开(公告)号：US07880466B2

公开(公告)日：2011-02-01

申请号：US11751479

申请日：2007-05-21

申请人： John Andrew Derbyshire ,  Daniel Alfredo Herzka ,  Elliot R. McVeigh

发明人： John Andrew Derbyshire ,  Daniel Alfredo Herzka ,  Elliot R. McVeigh

IPC分类号： G01V3/00

CPC分类号： G01R33/5613 ,  G01R33/483 ,  G01R33/5602 ,  G01R33/5607

摘要： A method for fat-suppressed imaging is disclosed. Such a method may include storing a first spectral component of an echo signal formed at TR/2 from a sample, suppressing a second spectral component of the echo signal at TR/2, re-exciting the stored spectral component after suppressing the second spectral component, and producing an image of the sample based on the re-excited stored spectral component.

摘要翻译： 公开了一种脂肪抑制成像方法。 这样的方法可以包括：存储来自样本的在TR / 2处形成的回波信号的第一频谱分量，以TR / 2抑制回波信号的第二频谱分量，在抑制第二频谱分量之后重新激励存储的频谱分量 并且基于重新存储的光谱分量产生样本的图像。

公开(公告)号：US06188219B1

公开(公告)日：2001-02-13

申请号：US09236054

申请日：1999-01-22

申请人： Scott B. Reeder ,  Ergin Atalar ,  Anthony Z. Faranesh ,  Elliot R. McVeigh

发明人： Scott B. Reeder ,  Ergin Atalar ,  Anthony Z. Faranesh ,  Elliot R. McVeigh

IPC分类号： G01V300

CPC分类号： G01R33/58

摘要： The invention provides a method of magnetic resonance imaging. A magnetic resonance imaging apparatus having a plurality of gradient axes is employed. A plurality of imaging planes are employed with respect to the gradient axes. A plurality of gradient referencing pre-scans are executed for the imaging planes to provide a plurality of calibration correction values for the imaging planes. A specimen is employed with respect to the gradient axes. An imaging plane is selected with respect to the specimen, and a main magnetic field is established with respect to the specimen. Radio frequency pulses are applied to the specimen to produce magnetic resonance signals. The calibration correction values for the selected imaging plane are employed to adjust a plurality of gradient waveforms. The gradient waveforms are output as a plurality of magnetic field gradients with respect to the gradient axes. Magnetic resonance information is acquired from the magnetic resonance signals corresponding to the radio frequency pulses. The magnetic resonance information is employed to display an image of the specimen. Associated apparatus and calibration method are also disclosed.

摘要翻译： 本发明提供一种磁共振成像方法。 采用具有多个梯度轴的磁共振成像装置。 相对于梯度轴采用多个成像平面。 对于成像平面执行多个梯度参考预扫描以为成像平面提供多个校准校正值。 相对于梯度轴使用试样。 相对于试样选择成像面，相对于试样建立主磁场。 将射频脉冲施加到样本以产生磁共振信号。 采用所选择的成像平面的校正校正值来调整多个梯度波形。 梯度波形相对于梯度轴被输出为多个磁场梯度。 从对应于射频脉冲的磁共振信号获取磁共振信息。 使用磁共振信息来显示样本的图像。 还公开了相关装置和校准方法。

公开(公告)号：US09008751B2

公开(公告)日：2015-04-14

申请号：US13305496

申请日：2011-11-28

申请人： Michael Guttman ,  Elliot R. McVeigh

发明人： Michael Guttman ,  Elliot R. McVeigh

IPC分类号： G06T15/08 ,  G01R33/56 ,  G01R33/563

CPC分类号： G06T15/08 ,  G01R33/5608 ,  G01R33/56308

摘要： A method of producing volume renderings from magnetic resonance image data in real time with user interactivity. The method comprises collecting raw magnetic resonance image (MRI) data representative of shapes within an image volume; transferring the raw MRI data to a computer; and continuously producing volume renderings from the raw MRI data in real time with respect to the act of collecting raw MRI data representative of shapes within the image volume.

摘要翻译： 一种利用用户交互性实时地从磁共振图像数据产生体积渲染的方法。 该方法包括收集表示图像体积内的形状的原始磁共振图像（MRI）数据; 将原始MRI数据传输到计算机; 并且相对于收集表示图像体积内的形状的原始MRI数据的动作，实时地从原始MRI数据生成体积效果图。

公开(公告)号：US07375520B2

公开(公告)日：2008-05-20

申请号：US11409511

申请日：2006-04-20

申请人： Reza Nezafat ,  J. Andrew Derbyshire ,  Ronald Ouwerkerk ,  Matthias Stuber ,  Elliot R. McVeigh

发明人： Reza Nezafat ,  J. Andrew Derbyshire ,  Ronald Ouwerkerk ,  Matthias Stuber ,  Elliot R. McVeigh

IPC分类号： G01V3/00

CPC分类号： G01R33/5635 ,  A61B5/0402 ,  A61B5/055 ,  A61B5/7285 ,  G01R33/5602

摘要： A T2 preparation sequence uses a segmented BIR-4 adiabatic pulse with two substantially equal delays and is insensitive to B1 field variations and can simultaneously suppress fat signals with low specific absorption rate (SAR). An adiabatic reverse half passage pulse is applied followed by a predetermined delay. An adiabatic full passage pulse is applied followed by a substantially equal delay, followed by an adiabatic half passage pulse. Fat signal suppression is achieved by increasing or decreasing either the first delay or the second delay.

摘要翻译： 制备序列使用具有两个基本相等的延迟的分段BIR-4绝热脉冲，并且对B＆lt; 1＆gt;场变化不敏感，并且可以同时抑制具有低比吸收率的脂肪信号 （特区）。 施加绝热的反向半通脉冲，然后施加预定的延迟。 施加绝热的全通脉冲，然后施加基本相等的延迟，随后是绝热的半通脉冲。 通过增加或减少第一延迟或第二延迟来实现脂肪信号抑制。