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    System and method for plasma reduced platelet collection
    4.
    发明授权
    System and method for plasma reduced platelet collection 有权
    血浆减少血小板收集的系统和方法

    公开(公告)号：US08454548B2

    公开(公告)日：2013-06-04

    申请号：US12102486

    申请日：2008-04-14

    申请人： Toshiyasu Ohashi ,  Etienne Pagès ,  Dominique Uhlmann ,  Pascal Maillard ,  Michael Ragusa

    发明人： Toshiyasu Ohashi ,  Etienne Pagès ,  Dominique Uhlmann ,  Pascal Maillard ,  Michael Ragusa

    IPC分类号： A61M37/00 ,  A61M1/36 ,  A61M1/38 ,  B01D36/00

    CPC分类号： A61M1/0263 ,  A61M1/0209 ,  A61M1/0218 ,  A61M1/0259 ,  A61M1/0272 ,  A61M1/029 ,  A61M1/3693 ,  A61M1/3696 ,  A61M1/38 ,  A61M1/382 ,  A61M2202/0413 ,  A61M2202/0427

    摘要： A method and apparatus for collecting plasma reduced platelets potentially suspended in a synthetic solution from a donor. Whole blood is drawn from the donor and introduced into a separation chamber. Platelets are extracted from the separation chamber into a container, using, for example, surge (with anticoagulated plasma or a synthetic solution) or push methodologies. The remaining blood components in the separation chamber are returned back to the donor. The steps of drawing whole blood and introducing the whole blood into the separation chamber, extracting platelets from the separation chamber into the container, and returning the remaining components in the chamber back to the donor are repeated. The sequestered platelets in the container are reintroduced into the separation chamber, whereupon a plasma reduced platelet product is extracted.

    摘要翻译： 一种用于收集可能悬浮在来自供体的合成溶液中的血浆还原血小板的方法和装置。 从供体抽出全血并引入分离室。 使用例如喘振（具有抗凝血浆或合成溶液）或推进方法将血小板从分离室提取到容器中。 分离室中的剩余血液成分返回给供体。 将全血全血引入分离室，将分离室中的血小板从容器中取出并将其中的剩余组分重新送回供体的步骤。 将容器中的隔离血小板重新引入分离室，从而提取血浆减少的血小板产物。

    System and method for automated platelet wash
    6.
    发明授权
    System and method for automated platelet wash 有权
    自动血小板洗涤的系统和方法

    公开(公告)号：US08808978B2

    公开(公告)日：2014-08-19

    申请号：US13883518

    申请日：2010-11-15

    申请人： Etienne Pagès ,  Dominique Uhlmann ,  Matthew Murphy

    发明人： Etienne Pagès ,  Dominique Uhlmann ,  Matthew Murphy

    IPC分类号： C12N5/078

    CPC分类号： B04B15/06 ,  A61M1/0281 ,  A61M1/3692 ,  A61M1/3693 ,  A61M1/3696 ,  B04B11/04 ,  B04B13/00 ,  C12N5/0644

    摘要： A method for washing platelets includes introducing anticoagulant into a platelet product container, drawing re-anticoagulated platelet product from the platelet product container, and introducing it into a centrifuge bowl. The centrifuge bowl separates the platelets from the supernatant in which they are suspended. The method then washes the platelets by introducing wash solution into the centrifuge bowl. As the wash solution is introduced into the bowl, it displaces the supernatant from the bowl and into a waste container. The method then introduces platelet additive solution into the centrifuge bowl, which displaces the wash solution from the centrifuge bowl and into the waste container and further wash the platelets. The method then repeatedly accelerates and decelerates the centrifuge bowl to resuspend the platelets in the platelet additive solution.

    摘要翻译： 洗涤血小板的方法包括将抗凝血剂引入血小板产品容器中，从血小板产品容器中抽出抗凝血小板产物，并将其引入离心机碗中。 离心机碗将血小板与悬浮的上清液分离。 该方法然后通过将洗涤溶液引入离心机碗中洗涤血小板。 当洗涤溶液被引入碗中时，它将上清液从碗中移出并进入废物容器。 然后，该方法将血小板添加剂溶液引入离心机碗中，将洗涤溶液从离心机碗排出并进入废液容器中，并进一步洗涤血小板。 该方法然后重复加速和减速离心机碗以使血小板重新悬浮在血小板添加剂溶液中。

    Three-line apheresis system and method
    7.
    发明授权
    Three-line apheresis system and method 有权
    三线血液分离系统及方法

    公开(公告)号：US08628489B2

    公开(公告)日：2014-01-14

    申请号：US12102407

    申请日：2008-04-14

    申请人： Etienne Pagès ,  Michael Ragusa

    发明人： Etienne Pagès ,  Michael Ragusa

    IPC分类号： A61M37/00 ,  A61M1/00 ,  A61M1/14 ,  A61M1/36

    CPC分类号： A61M1/367 ,  A61M1/0209 ,  A61M1/0218 ,  A61M1/30 ,  A61M1/303 ,  A61M1/304 ,  A61M1/3601 ,  A61M1/3603 ,  A61M1/3604 ,  A61M1/3621 ,  A61M1/3693 ,  A61M1/3696 ,  A61M1/38 ,  A61M1/387 ,  A61M2202/0071

    摘要： A blood processing system for collecting and exchanging blood components includes a venous-access device for drawing whole blood from a subject and returning blood components to the subject. The system may also include three lines connecting the venous access device to a blood component separation device and an anticoagulant source. A blood draw line fluidly connects to the venous-access device to the blood component separation device. An anticoagulant line introduces anticoagulant into the drawn whole blood. A return line, fluidly connected to the venous-access device and the blood component separation device, and returns uncollected blood component to the subject. Each line may have a pump that controls flow through the line. The blood component separation device separates the drawn blood into a first blood component and a second blood component, and may be configured to send the first blood component to a first blood component bag.

    摘要翻译： 用于收集和交换血液成分的血液处理系统包括用于从对象抽取全血并将血液成分返回到受试者的静脉通路装置。 该系统还可以包括将静脉进入装置连接到血液成分分离装置和抗凝血剂源的三条线。 血液抽吸管线与静脉通路装置流体连接到血液成分分离装置。 抗凝血剂线将抗凝血剂引入全血中。 流体地连接到静脉通路装置和血液成分分离装置的返回管线，并将未收集的血液成分返回给受试者。 每条线路可能都有一个泵来控制通过管路的流量。 血液成分分离装置将抽取的血液分离成第一血液成分和第二血液成分，并且可以将第一血液成分发送到第一血液成分袋。