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公开(公告)号:US09017712B2
公开(公告)日:2015-04-28
申请号:US13809432
申请日:2011-07-11
申请人: Il Hwan Cho , Eui Jin Hwang , Moo Seok Seo , Young Soo Park , Byung Su Kim , Sei Kwang Hahn , Jung Kyu Park , Jun Seok Yeom , Eun Ju Oh
发明人: Il Hwan Cho , Eui Jin Hwang , Moo Seok Seo , Young Soo Park , Byung Su Kim , Sei Kwang Hahn , Jung Kyu Park , Jun Seok Yeom , Eun Ju Oh
IPC分类号: A61K8/73 , A61Q19/08 , A61K31/167 , A61L27/20 , A61L27/52 , C08B37/08 , C08J3/075 , C08L5/08 , A61L27/54
CPC分类号: A61K8/735 , A61K31/167 , A61L27/20 , A61L27/52 , A61L27/54 , A61L2300/402 , A61L2400/06 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J2305/08 , C08L5/08
摘要: The present invention relates to a filler composition for tissue reinforcement, including hyaluronic acid and alkylene diamine crosslinked hydrogel. The filler composition exhibits the positive physical properties required for tissue reinforcement, such as biocompatibility and swelling ability, as well as useful effects in that the same can remain in vivo for a long time.
摘要翻译: 本发明涉及用于组织增强的填充剂组合物,包括透明质酸和亚烷基二胺交联的水凝胶。 填充剂组合物显示组织增强所需的正性物理性质,例如生物相容性和溶胀能力,以及有益效果,因为它们长时间保留在体内。
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公开(公告)号:US20110237542A1
公开(公告)日:2011-09-29
申请号:US13131996
申请日:2009-11-25
申请人: Il Hwan Cho , Sei Kwang Hahn , Eui Jin Hwang , Jang Sik Shin , Junseok Yeom
发明人: Il Hwan Cho , Sei Kwang Hahn , Eui Jin Hwang , Jang Sik Shin , Junseok Yeom
IPC分类号: A61K31/728 , A61P17/02
CPC分类号: A61K31/722 , A61K31/728
摘要: The present invention relates to a composition for preventing tissue adhesion which comprising a bio-compatible hyaluronic acid and a polymer compound. More specifically, the invention is a composition containing hyaluronic acid which has not been modified by a chemical crosslinking or other chemical modification a method for preparing the same, and a composition for adhesion prevention with superior efficacy.The composition of the present invention for preventing adhesion exhibits a physical barrier function and a new adhesion prevention function whereby thrombus formation, which is the basis of adhesion, is inhibited. Unlike conventional compositions which simply mixpolymeric substances that function as physical barriers, the present invention performs a more effective role as a physical barrier by undergoing decomposition, absorption and excretion after a certain period inside a human body, does not interfere with healing of scars following surgery, and exhibits superior effects since application to areas of surgery is convenient.
摘要翻译: 本发明涉及一种用于预防组织粘连的组合物,其包含生物相容性透明质酸和高分子化合物。 更具体地说,本发明是含有未被化学交联或其它化学改性改性的透明质酸的组合物及其制备方法,以及具有优异功效的防粘组合物。 用于防止粘附的本发明的组合物显示出物理屏障功能和新的粘附防止功能,其中作为粘附基础的血栓形成被抑制。 不同于简单地混合作为物理障碍物的混合物质的常规组合物,本发明通过在人体内经过一定时间后经历分解,吸收和排泄而作为物理屏障起到更有效的作用,不影响手术后瘢痕愈合 ,并且表现出优异的效果,因为应用于手术领域是方便的。
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公开(公告)号:US20130203856A1
公开(公告)日:2013-08-08
申请号:US13809432
申请日:2011-07-11
申请人: Il Hwan Cho , Eui Jin Hwang , Moo Seok Seo , Young Soo Park , Byung Su Kim , Sei Kwang Hahn , Jung Kyu Park , Jun Seok Yeom , Eun Ju Oh
发明人: Il Hwan Cho , Eui Jin Hwang , Moo Seok Seo , Young Soo Park , Byung Su Kim , Sei Kwang Hahn , Jung Kyu Park , Jun Seok Yeom , Eun Ju Oh
IPC分类号: A61K8/73 , A61Q19/08 , A61K31/167
CPC分类号: A61K8/735 , A61K31/167 , A61L27/20 , A61L27/52 , A61L27/54 , A61L2300/402 , A61L2400/06 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J2305/08 , C08L5/08
摘要: The present invention relates to a filler composition for tissue reinforcement, including hyaluronic acid and alkylene diamine crosslinked hydrogel. The filler composition exhibits the positive physical properties required for tissue reinforcement, such as biocompatibility and swelling ability, as well as useful effects in that the same can remain in vivo for a long time.
摘要翻译: 本发明涉及用于组织增强的填充剂组合物,包括透明质酸和亚烷基二胺交联的水凝胶。 填充剂组合物显示组织增强所需的正性物理性质,例如生物相容性和溶胀能力,以及有益效果,因为它们长时间保留在体内。
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公开(公告)号:US20060078905A1
公开(公告)日:2006-04-13
申请号:US11138981
申请日:2005-05-26
申请人: Sang-Ryoul Park , In-Chul Yang , Myung-Sub Han , Yong-Hyeon Yim , Eui-Jin Hwang
发明人: Sang-Ryoul Park , In-Chul Yang , Myung-Sub Han , Yong-Hyeon Yim , Eui-Jin Hwang
IPC分类号: C12Q1/68
CPC分类号: C12Q1/68 , C12Q2545/114 , C12Q2523/301 , C12Q2523/107
摘要: The present invention is related to a novel approach for quantitation of DNA based on the stoichiometric existence of phosphorus (P) in DNA.
摘要翻译: 本发明涉及基于DNA中磷(P)的化学计量存在的DNA定量的新方法。
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公开(公告)号:US07294467B2
公开(公告)日:2007-11-13
申请号:US11138981
申请日:2005-05-26
申请人: Sang-Ryoul Park , In-Chul Yang , Myung-Sub Han , Yong-Hyeon Yim , Eui-Jin Hwang
发明人: Sang-Ryoul Park , In-Chul Yang , Myung-Sub Han , Yong-Hyeon Yim , Eui-Jin Hwang
CPC分类号: C12Q1/68 , C12Q2545/114 , C12Q2523/301 , C12Q2523/107
摘要: The present invention is related to a novel approach for quantitation of DNA based on the stoichiometric existence of phosphorus (P) in DNA.
摘要翻译: 本发明涉及基于DNA中磷(P)的化学计量存在的DNA定量的新方法。
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公开(公告)号:US08703740B2
公开(公告)日:2014-04-22
申请号:US13131996
申请日:2009-11-25
申请人: Il Hwan Cho , Sei Kwang Hahn , Eui Jin Hwang , Jang Sik Shin , Junseok Yeom
发明人: Il Hwan Cho , Sei Kwang Hahn , Eui Jin Hwang , Jang Sik Shin , Junseok Yeom
IPC分类号: A61K31/728
CPC分类号: A61K31/722 , A61K31/728
摘要: The present invention relates to a composition for preventing tissue adhesion which comprising a bio-compatible hyaluronic acid and a polymer compound. More specifically, the invention is a composition containing hyaluronic acid which has not been modified by a chemical crosslinking or other chemical modification a method for preparing the same, and a composition for adhesion prevention with superior efficacy.The composition of the present invention for preventing adhesion exhibits a physical barrier function and a new adhesion prevention function whereby thrombus formation, which is the basis of adhesion, is inhibited. Unlike conventional compositions which simply mix polymeric substances that function as physical barriers, the present invention performs a more effective role as a physical barrier by undergoing decomposition, absorption and excretion after a certain period inside a human body, does not interfere with healing of scars following surgery, and exhibits superior effects since application to areas of surgery is convenient.
摘要翻译: 本发明涉及一种用于预防组织粘连的组合物,其包含生物相容性透明质酸和高分子化合物。 更具体地说,本发明是含有未被化学交联或其它化学改性改性的透明质酸的组合物及其制备方法,以及具有优异功效的粘着防止用组合物。 用于防止粘附的本发明的组合物显示出物理屏障功能和新的粘附防止功能,其中作为粘附基础的血栓形成被抑制。 不同于简单地混合作为物理屏障的聚合物质的常规组合物,本发明通过在人体内经过一定时间后经历分解,吸收和排泄而作为物理屏障起到更有效的作用,不影响瘢痕愈合 手术,并且表现出优异的效果,因为应用于手术领域是方便的。
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