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公开(公告)号：US08828210B2
公开(公告)日：2014-09-09
申请号：US12738268
申请日：2008-10-16
Applicant: Chris Abell , Wilhelm T. S. Huck , Daniel Bratton , Graeme Whyte , Luis M. Fidalgo
Inventor： Chris Abell , Wilhelm T. S. Huck , Daniel Bratton , Graeme Whyte , Luis M. Fidalgo
CPC classification number: B01J19/0093 , B01J2219/00576 , B01J2219/00599 , B01J2219/00783 , B01J2219/00831 , B01J2219/00833 , B01J2219/00853 , B01J2219/0086 , B01J2219/00891 , B01J2219/0097 , B01L3/502761 , B01L3/502784 , B01L2300/0867 , B01L2400/0415 , B01L2400/043 , G01N2035/00158
Abstract: This invention relates to microfluidic systems and more particularly to methods and apparatus for accessing the contents of micro droplets (114) in an emulsion stream. A method of accessing the contents of a droplet (114) of an emulsion in a microfluidic system, the method comprising: flowing the emulsion alongside a continuous, non-emulsive stream of second fluid (118) to provide an interface (120) between said emulsion and said stream of second fluid (118); and in embodiments applying one or both of an electric (112a, 112b) and magnetic field across said interface (120) to alter a trajectory of a said droplet (114) of said emulsion to cause said droplet to coalesce with said stream of second fluid (118); and accessing said contents of said droplet (114) in said second stream (118).
Abstract translation: 本发明涉及微流体系统，更具体地涉及用于访问乳液流中微滴（114）的内容物的方法和装置。 一种在微流体系统中接触乳液液滴（114）的内容物的方法，所述方法包括：使乳液与第二流体（118）的连续的非乳化流一起流动，以在所述第二流体（118）之间提供界面（120） 乳液和所述第二流体流（118）; 并且在实施例中应用电（112a，112b）和磁场中的一个或两个穿过所述界面（120）以改变所述乳液的所述液滴（114）的轨迹，以使所述液滴与所述第二流体流 （118）; 以及访问所述第二流（118）中的所述液滴（114）的所述内容物。
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Patent Agency Ranking
公开(公告)号：US20120091004A1
公开(公告)日：2012-04-19
申请号：US12738268
申请日：2008-10-16
Applicant: Chris Abell , Wilhelm T.S. Huck , Daniel Bratton , Graeme Whyte , Luis M. Fidalgo
Inventor： Chris Abell , Wilhelm T.S. Huck , Daniel Bratton , Graeme Whyte , Luis M. Fidalgo
CPC classification number: B01J19/0093 , B01J2219/00576 , B01J2219/00599 , B01J2219/00783 , B01J2219/00831 , B01J2219/00833 , B01J2219/00853 , B01J2219/0086 , B01J2219/00891 , B01J2219/0097 , B01L3/502761 , B01L3/502784 , B01L2300/0867 , B01L2400/0415 , B01L2400/043 , G01N2035/00158
Abstract: This invention relates to microfluidic systems and more particularly to methods and apparatus for accessing the contents of micro droplets (114) in an emulsion stream. A method of accessing the contents of a droplet (114) of an emulsion in a microfluidic system, the method comprising: flowing the emulsion alongside a continuous, non-emulsive stream of second fluid (118) to provide an interface (120) between said emulsion and said stream of second fluid (118); and in embodiments applying one or both of an electric (112a, 112b) and magnetic field across said interface (120) to alter a trajectory of a said droplet (114) of said emulsion to cause said droplet to coalesce with said stream of second fluid (118); and accessing said contents of said droplet (114) in said second stream (118).
Abstract translation: 本发明涉及微流体系统，更具体地涉及用于访问乳液流中微滴（114）的内容物的方法和装置。 一种在微流体系统中接触乳液液滴（114）的内容物的方法，所述方法包括：使乳液与第二流体（118）的连续的非乳化流一起流动，以在所述第二流体（118）之间提供界面（120） 乳液和所述第二流体流（118）; 并且在实施例中应用电（112a，112b）和磁场中的一个或两个穿过所述界面（120）以改变所述乳液的所述液滴（114）的轨迹，以使所述液滴与所述第二流体流 （118）; 以及访问所述第二流（118）中的所述液滴（114）的所述内容物。
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公开(公告)号：US09151685B2
公开(公告)日：2015-10-06
申请号：US13585988
申请日：2012-08-15
Applicant: Dongxu Li , Graeme Whyte , Robert J. Horner , Jerry Paul Sagady , Amin Abboud
Inventor： Dongxu Li , Graeme Whyte , Robert J. Horner , Jerry Paul Sagady , Amin Abboud
Abstract: A method for monitoring torque in a gear train includes coincidently determining angles of rotation of first and second rotationally coupled members of the gear train. Each of the members employs a respective rotational position sensor. Each of said angles of rotation are determined based upon times corresponding to a last signal pulse, a next-to-last signal pulse, and a total quantity of signal pulses generated by the respective rotational position sensor during a current sampling interval. A twist angle corresponding to a difference between the angles of rotation of the first and second rotationally coupled members of the gear train is determined, and torque corresponding to the twist angle is calculated.
Abstract translation: 用于监测齿轮系中的扭矩的方法包括一致地确定齿轮系的第一和第二旋转联接构件的旋转角度。 每个构件采用相应的旋转位置传感器。 所述旋转角度中的每一个基于对应于最后信号脉冲，下一个到最后信号脉冲的时间以及在当前采样间隔期间由相应的旋转位置传感器产生的信号脉冲的总量来确定。 确定与齿轮系的第一和第二旋转联接构件的旋转角度之间的差异相对应的扭转角度，并且计算与扭转角度相对应的扭矩。
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公开(公告)号：US09267918B2
公开(公告)日：2016-02-23
申请号：US13725459
申请日：2012-12-21
Applicant: Tony R. Joaquim , Lewis Joe Stafford , Ross Stewart Chambers , Xin Liu , Clive Adrian Smith , Xin Li , Graeme Whyte
Inventor： Tony R. Joaquim , Lewis Joe Stafford , Ross Stewart Chambers , Xin Liu , Clive Adrian Smith , Xin Li , Graeme Whyte
IPC: G01N27/447 , G01N15/14 , B01L3/00 , B01L3/02
CPC classification number: G01N27/44791 , B01L3/0268 , B01L3/502784 , B01L2200/0652 , B01L2200/0673 , B01L2400/0415 , B01L2400/043 , G01N15/1484 , G01N2015/149
Abstract: A flow cell for a microfluidic device can include a chamber, first microfluidic entry and exit channels, second microfluidic entry and exit channels, a first electrode, and a second electrode. A microfluidic device can include a microfluidic channel, a laser to excite fluorescent material, and a detector to detect fluorescence emission. Methods of merging a droplet from an emulsion in to a second stream of fluid and of detecting a content of a droplet in a stream are further disclosed.
Abstract translation: 用于微流体装置的流动池可以包括室，第一微流体入口和出口通道，第二微流体入口和出口通道，第一电极和第二电极。 微流体装置可以包括微流体通道，激发荧光材料的激光器和检测器以检测荧光发射。 进一步公开了将液滴从乳液合并到第二流体流中并且检测流中的液滴含量的方法。
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公开(公告)号：US20140021049A1
公开(公告)日：2014-01-23
申请号：US13725459
申请日：2012-12-21
Applicant: Tony R. JOAQUIM , Lewis Joe Stafford , Ross Stewart Chambers , Xin Liu , Clive Adrian Smith , Xin Li , Graeme Whyte
Inventor： Tony R. JOAQUIM , Lewis Joe Stafford , Ross Stewart Chambers , Xin Liu , Clive Adrian Smith , Xin Li , Graeme Whyte
IPC: G01N27/447
CPC classification number: G01N27/44791 , B01L3/0268 , B01L3/502784 , B01L2200/0652 , B01L2200/0673 , B01L2400/0415 , B01L2400/043 , G01N15/1484 , G01N2015/149
Abstract: A flow cell for a microfluidic device can include a chamber, first microfluidic entry and exit channels, second microfluidic entry and exit channels, a first electrode, and a second electrode. A microfluidic device can include a microfluidic channel, a laser to excite fluorescent material, and a detector to detect fluorescence emission. Methods of merging a droplet from an emulsion in to a second stream of fluid and of detecting a content of a droplet in a stream are further disclosed.
Abstract translation: 用于微流体装置的流动池可以包括室，第一微流体入口和出口通道，第二微流体入口和出口通道，第一电极和第二电极。 微流体装置可以包括微流体通道，激发荧光材料的激光器和检测器以检测荧光发射。 进一步公开了将液滴从乳液合并到第二流体流中并且检测流中的液滴含量的方法。
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公开(公告)号：US20130218426A1
公开(公告)日：2013-08-22
申请号：US13585988
申请日：2012-08-15
Applicant: Dongxu LI , Graeme Whyte , Robert J. Horner , Jerry Paul Sagady , Amin Abboud
Inventor： Dongxu LI , Graeme Whyte , Robert J. Horner , Jerry Paul Sagady , Amin Abboud
IPC: G01L3/02
Abstract: A method for monitoring torque in a gear train includes coincidentally determining angles of rotation of first and second rotationally coupled members of the gear train. Each of the members employs a respective rotational position sensor. Each of said angles of rotation are determined based upon times corresponding to a last signal pulse, a next-to-last signal pulse, and a total quantity of signal pulses generated by the respective rotational position sensor during a current sampling interval. A twist angle corresponding to a difference between the angles of rotation of the first and second rotationally coupled members of the gear train is determined, and torque corresponding to the twist angle is calculated.
Abstract translation: 用于监测齿轮系中的扭矩的方法包括巧妙地确定齿轮系的第一和第二旋转联接构件的旋转角度。 每个构件采用相应的旋转位置传感器。 所述旋转角度中的每一个基于对应于最后信号脉冲，下一个到最后信号脉冲的时间以及在当前采样间隔期间由相应的旋转位置传感器产生的信号脉冲的总量来确定。 确定与齿轮系的第一和第二旋转联接构件的旋转角度之间的差异相对应的扭转角度，并且计算与扭转角度相对应的扭矩。
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