利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

15 条记录 (耗时 0.03 秒)

    Systems and methods for alignment of objects in images
    1.
    发明申请
    Systems and methods for alignment of objects in images 失效
    图像中对象对齐的系统和方法

    公开(公告)号：US20080317307A1

    公开(公告)日：2008-12-25

    申请号：US11820939

    申请日：2007-06-21

    申请人： Peng Lu ,  Ming Zheng ,  Guochun Liao

    发明人： Peng Lu ,  Ming Zheng ,  Guochun Liao

    IPC分类号： G06K9/00

    CPC分类号： G01R33/46 ,  G01N24/08 ,  G01R33/4633 ,  G01R33/465 ,  G01R33/5608 ,  G06T7/30 ,  G06T2207/10088

    摘要： Systems and methods for aligning objects in object sets are provided. An object set has objects that are in a corresponding image in a plurality of images. For each respective object in a first object set, a corresponding object group is constructed that contains the respective object, thereby constructing a plurality of object groups. Similarity metrics are computed between object groups and objects in objects sets in order to assign the objects to object groups. The object groups are then refined in order to align objects in the object sets.

    摘要翻译： 提供了对象集中对象对齐的系统和方法。 对象集合具有在多个图像中的对应图像中的对象。 对于第一对象集合中的每个对象，构造包含相应对象的对应对象组，从而构造多个对象组。 在对象集中的对象组和对象之间计算相似性度量，以便将对象分配给对象组。 然后对对象组进行细化，以便对齐对象中的对象。

    Systems and methods for processing nucleic acid chromatograms
    2.
    发明申请
    Systems and methods for processing nucleic acid chromatograms 失效
    用于处理核酸色谱图的系统和方法

    公开(公告)号：US20060058969A1

    公开(公告)日：2006-03-16

    申请号：US10942538

    申请日：2004-09-15

    申请人： Guochun Liao ,  Jonathan Usuka ,  Gary Peltz

    发明人： Guochun Liao ,  Jonathan Usuka ,  Gary Peltz

    IPC分类号： G06F19/00

    CPC分类号： G06F19/22

    摘要： Computer systems, computer program products and methods for processing an input nucleic acid chromatogram having a plurality of substantially simultaneous traces. Each trace in the plurality of traces has a plurality of datapoints. Each respective datapoint in each of the plurality of datapoints represents a signal amplitude at a position in the trace corresponding to the respective datapoint. A first peak is identified in a first trace that is substantially overlapping a second peak in a second trace in the plurality of traces. The first peak is outputted to a first output homozygous representation and the second peak is outputted to a second output homozygous representation. The first output homozygous representation is a first homozygous sequence representation or a first homozygous nucleic acid chromatogram corresponding to the input nucleic acid chromatogram. The second output homozygous representation is a second homozygous sequence representation or second homozygous nucleic acid chromatogram of the input nucleic acid chromatogram.

    摘要翻译： 计算机系统，计算机程序产品和用于处理具有多个基本上同时的踪迹的输入核酸色谱图的方法。 多个迹线中的每个迹线具有多个数据点。 多个数据点中的每一个中的每个相应数据点表示对应于相应数据点的轨迹位置处的信号振幅。 在第一迹线中识别出第一峰值，其基本上与多个迹线中的第二迹线中的第二峰值重叠。 将第一峰值输出到第一输出纯合表示，并将第二峰值输出到第二输出纯合表示。 第一个输出纯合表达是对应于输入核酸色谱图的第一个纯合序列表示或第一个纯合的核酸色谱图。 第二个输出纯合表达是输入核酸色谱图的第二个纯合序列表示或第二个纯合的核酸色谱图。

    METHODS AND SYSTEMS FOR SEQUENCING LONG NUCLEIC ACIDS
    3.
    发明申请
    METHODS AND SYSTEMS FOR SEQUENCING LONG NUCLEIC ACIDS 审中-公开
    用于测序长核酸的方法和系统

    公开(公告)号：US20140315724A1

    公开(公告)日：2014-10-23

    申请号：US14009089

    申请日：2012-04-02

    申请人： Wei Zhou ,  Rui Mei ,  Filip Crnogorac ,  Guochun Liao ,  Julian Lucas

    发明人： Wei Zhou ,  Rui Mei ,  Filip Crnogorac ,  Guochun Liao ,  Julian Lucas

    IPC分类号： C12Q1/68

    摘要： The present invention provides methods and systems for sequencing long nucleic acid fragments. In one aspect of the invention, methods, systems and reagent kits are provided for sequencing nucleic acid target sequences. Some embodiments of the methods, systems and reagent kits are particularly suitable for sequencing a large number of fragments, particularly long fragments.

    摘要翻译： 本发明提供了用于测序长核酸片段的方法和系统。 在本发明的一个方面，提供了用于测序核酸靶序列的方法，系统和试剂盒。 方法，系统和试剂盒的一些实施方案特别适用于测序大量片段，特别是长片段。

    LED lamp with high efficacy and high color rendering and manufacturing method thereof
    4.
    发明授权
    LED lamp with high efficacy and high color rendering and manufacturing method thereof 有权
    具有高效率和高显色性的LED灯具及其制造方法

    公开(公告)号：US08193735B2

    公开(公告)日：2012-06-05

    申请号：US12527021

    申请日：2008-02-15

    申请人： Lan Wei ,  Junxiang Han ,  Guochun Liao

    发明人： Lan Wei ,  Junxiang Han ,  Guochun Liao

    IPC分类号： G05F1/00 ,  H05B37/02 ,  H05B39/04 ,  H05B41/36

    CPC分类号： H05B33/0857 ,  F21K9/00 ,  F21Y2115/10 ,  H05B33/0809 ,  Y02B20/341

    摘要： A LED lamp and a manufacturing method thereof are disclosed. At least one blue LED chip can be used as an excitation light source. A number of red LED chips are arranged around the blue LED chip. The blue LED chip and red chips are covered with a packaging material with phosphor. The intensity of red light can be adjusted by a control circuit. Thus, the white LED lamps with high efficacy and high color rendering at different color temperatures can be achieved.

    摘要翻译： 公开了一种LED灯及其制造方法。 至少可以使用一个蓝色LED芯片作为激发光源。 蓝色LED芯片周围布置了许多红色LED芯片。 蓝色LED芯片和红色芯片用包含磷光体的材料覆盖。 红光的强度可以通过控制电路来调节。 因此，可以实现在不同色温下具有高效率和高显色性的白色LED灯。

    Compositions and methods for reducing the risk of agent-induced liver toxicity
    9.
    发明授权
    Compositions and methods for reducing the risk of agent-induced liver toxicity 失效
    降低药物诱导的肝毒性风险的组合物和方法

    公开(公告)号：US08685956B2

    公开(公告)日：2014-04-01

    申请号：US13395736

    申请日：2010-09-16

    申请人： Hong-Hsing Liu ,  Gary Allen Peltz ,  Guochun Liao ,  Timothy Alan Garrow

    发明人： Hong-Hsing Liu ,  Gary Allen Peltz ,  Guochun Liao ,  Timothy Alan Garrow

    IPC分类号： A61K31/33

    CPC分类号： A61K31/167 ,  A61K31/198 ,  A61K31/205 ,  A61K2300/00

    摘要： The present disclosure relates generally to a pharmaceutical compositions and methods of reducing acetaminophen-induced liver toxicity. The disclosure includes pharmaceutical compositions including acetaminophen and one or more components selected from S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof. The disclosure also relates to methods of reducing acetaminophen-induced liver toxicity in a subject by administering or co-administering one or more of S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof, with acetaminophen to a subject.

    摘要翻译： 本公开一般涉及减少对乙酰氨基酚诱导的肝毒性的药物组合物和方法。 本公开内容包括药物组合物，包括对乙酰氨基酚和选自S-腺苷高半胱氨酸（SAH），S-甲基甲硫氨酸（SMM）或其药学上可接受的盐的一种或多种组分。 本公开还涉及通过将一种或多种S-腺苷高半胱氨酸（SAH），S-甲基甲硫氨酸（SMM）或其药学上可接受的盐与对乙酰氨基酚给予或共同给予或共同给予或共同施用对乙酰氨基酚诱导的肝毒性的方法 课程。

    COMPOSITIONS AND METHODS FOR REDUCING THE RISK OF AGENT-INDUCED LIVER TOXICITY
    10.
    发明申请
    COMPOSITIONS AND METHODS FOR REDUCING THE RISK OF AGENT-INDUCED LIVER TOXICITY 失效
    用于降低代谢诱导性肝毒性风险的组合物和方法

    公开(公告)号：US20120172324A1

    公开(公告)日：2012-07-05

    申请号：US13395736

    申请日：2010-09-16

    申请人： Hong-Hsing Liu ,  Gary Allen Peltz ,  Guochun Liao ,  Timothy Alan Garrow

    发明人： Hong-Hsing Liu ,  Gary Allen Peltz ,  Guochun Liao ,  Timothy Alan Garrow

    IPC分类号： A61K31/7076 ,  A61P29/00 ,  A61K31/167 ,  A61P1/16 ,  A61K31/205 ,  A61K31/198

    CPC分类号： A61K31/167 ,  A61K31/198 ,  A61K31/205 ,  A61K2300/00

    摘要： The present disclosure relates generally to a co-formulation or co-administration of acetaminophen with one or more chemicals that are metabolites or their derivatives in the methionine and glutathione biosynthesis pathways, for protection against acetaminophen-induced liver toxicity. The formulation may comprise acetaminophen and diet supplements such as S-methylmethionine (SMM). The present disclosure also encompasses methods of providing pain or fever relief with protection against acetaminophen-induced liver injury with the formulations described herein. Embodiments of the present disclosure also include co-formulation or co-administration of an agent and one or more other chemicals for reducing agent-induced liver toxicity via depletion of glutathione.

    摘要翻译： 本公开一般涉及对乙酰氨基酚与一种或多种在甲硫氨酸和谷胱甘肽生物合成途径中作为代谢物或其衍生物的化学品的共同配制或共同给药，以防止对乙酰氨基酚诱导的肝毒性。 制剂可以包括对乙酰氨基酚和膳食补充剂，例如S-甲基甲硫氨酸（SMM）。 本公开还包括使用本文所述的制剂提供疼痛或发烧缓解的方法，以防止对乙酰氨基酚诱导的肝损伤。 本公开的实施方案还包括通过耗尽谷胱甘肽来共同配制或共同施用药剂和一种或多种其它用于还原剂诱导的肝毒性的化学品。