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公开(公告)号：US08920152B2
公开(公告)日：2014-12-30
申请号：US13531735
申请日：2012-06-25
Applicant: H. Gene Hawkins , William Hartman , Kristen Martin , Nathan A. Winslow
Inventor： H. Gene Hawkins , William Hartman , Kristen Martin , Nathan A. Winslow
CPC classification number: A61F2/36 , A61F2/30 , A61F2/3094 , A61F2/3662 , A61F2/38 , A61F2/40 , A61F2002/3009 , A61F2002/30332 , A61F2002/30471 , A61F2002/30604 , A61F2002/30672 , A61F2002/30957 , A61F2002/3611 , A61F2002/365 , A61F2220/0033 , A61F2220/0091 , A61F2250/0091 , A61F2310/00353 , B28B7/0029 , B28B7/0044 , B28B23/024
Abstract: The present teachings provide a modular articulating cement spacer mold for forming a temporary implant comprising a mold first portion, a mold second portion, and a ventilation forming surface feature on an interior surface of at least one of the mold first portion or the mold second portion. The first mold portion and the second mold portion have corresponding interior surfaces that form a cavity therebetween.
Abstract translation: 本发明提供了一种用于形成临时植入物的模块化关节式水泥隔离器模具，其包括模具第一部分，模具第二部分和通气形成表面特征，其在模具第一部分或模具第二部分中的至少一个的内表面上 。 第一模具部分和第二模具部分具有在其间形成空腔的对应内表面。
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2.发明授权Crosslinked polymeric material with enhanced strength and process for manufacturing 有权具有增强强度的交联聚合物材料和制造方法公开(公告)号：US07780896B2
公开(公告)日：2010-08-24
申请号：US12328414
申请日：2008-12-04
Applicant: David W. Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
Inventor： David W. Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
CPC classification number: C08J3/24 , A61F2/3094 , A61F2/34 , A61L27/16 , B29C47/0016 , B29C47/003 , B29C47/884 , B29C55/30 , B29K2023/0683 , B29K2623/0683 , B29L2031/7532 , C08J2323/06 , C08L23/06
Abstract: A radiation crosslinked (50 kGy), pressure-treated UHMWPE material has been developed by applying compressive force on a crosslinked polymer in a direction orthogonal to an axial direction. The deformed material is then cooled while held in a deformed state. The resulting material is anisotropic, with enhanced strength oriented along the axial direction. The directionally engineered material is oxidatively stable even after four weeks of accelerated aging in a pressure vessel containing five atmospheres of oxygen (ASTM F2003). Because of its oxidative stability, the deformation processed material is a suitable candidate for air-permeable packaging and gas sterilization, which has thus far been reserved for remelted highly crosslinked UHMWPEs.
Abstract translation: 已经通过在与轴向正交的方向上对交联聚合物施加压缩力来开发经辐射交联（50kGy）的经加压处理的UHMWPE材料。 然后将变形的材料冷却，同时保持在变形状态。 所得到的材料是各向异性的，具有沿轴向取向的增强强度。 即使在含有五个大气压的氧气的压力容器（ASTM F2003）中，即使在加速老化四周之后，定向工程材料也是氧化稳定的。 由于其氧化稳定性，变形处理材料是透气包装和气体灭菌的合适的候选物，迄今为止，这已经被保留用于重熔的高度交联的UHMWPE。
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3.发明授权公开(公告)号：US07547405B2
公开(公告)日：2009-06-16
申请号：US11402561
申请日：2006-04-12
Applicant: David Wayne Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
Inventor： David Wayne Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
CPC classification number: C08J3/28
Abstract: Solid-state deformation processing of crosslinked high molecular weight polymers such as UHMWPE, for example by extrusion below the melt transition, produces materials with a desirable combination of physical and chemical properties. Crosslinked bulk materials are heated to a compression deformable temperature, and pressure is applied to change a transverse dimension of the material. After cooling and stress relieving, a treated bulk material is obtained that has enhanced tensile strength in the axial direction orthogonal to the dimension change. In preferred embodiments, medical implant bearing materials are machined from the treated bulk material with the in vivo load bearing axis substantially parallel or coincident with the axial direction of the treated bulk material.
Abstract translation: 交联的高分子量聚合物如UHMWPE的固态变形处理例如通过在熔融转变以下挤出产生具有所需物理和化学性质组合的材料。 将交联的散装材料加热至压缩变形温度，施加压力以改变材料的横向尺寸。 在冷却和减轻应力之后，获得了与尺寸变化正交的轴向拉伸强度提高的经处理的散装材料。 在优选实施例中，医疗植入物轴承材料由经处理的散装材料加工，其中体内承载轴线基本上与经处理的散装材料的轴向方向平行或重合。
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4.发明申请CROSSLINKED POLYMERIC MATERIAL WITH ENHANCED STRENGTH AND PROCESS FOR MANUFACTURING 有权具有增强强度的交联聚合材料和制造工艺公开(公告)号：US20090082546A1
公开(公告)日：2009-03-26
申请号：US12328414
申请日：2008-12-04
Applicant: David W. SCHROEDER , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
Inventor： David W. SCHROEDER , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
IPC: C08F6/26
CPC classification number: C08J3/24 , A61F2/3094 , A61F2/34 , A61L27/16 , B29C47/0016 , B29C47/003 , B29C47/884 , B29C55/30 , B29K2023/0683 , B29K2623/0683 , B29L2031/7532 , C08J2323/06 , C08L23/06
Abstract: A radiation crosslinked (50 kGy), pressure-treated UHMWPE material has been developed by applying compressive force on a crosslinked polymer in a direction orthogonal to an axial direction. The deformed material is then cooled while held in a deformed state. The resulting material is anisotropic, with enhanced strength oriented along the axial direction. The directionally engineered material is oxidatively stable even after four weeks of accelerated aging in a pressure vessel containing five atmospheres of oxygen (ASTM F2003). Because of its oxidative stability, the deformation processed material is a suitable candidate for air-permeable packaging and gas sterilization, which has thus far been reserved for remelted highly crosslinked UHMWPEs.
Abstract translation: 已经通过在与轴向正交的方向上对交联聚合物施加压缩力来开发经辐射交联（50kGy）的经加压处理的UHMWPE材料。 然后将变形的材料冷却，同时保持在变形状态。 所得到的材料是各向异性的，具有沿轴向取向的增强强度。 即使在含有五个大气压的氧气的压力容器（ASTM F2003）中，即使在加速老化四周之后，定向工程材料也是氧化稳定的。 由于其氧化稳定性，变形处理材料是透气包装和气体灭菌的合适的候选物，迄今为止，这已经被保留用于重熔的高度交联的UHMWPE。
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5.发明授权公开(公告)号：US07344672B2
公开(公告)日：2008-03-18
申请号：US10963974
申请日：2004-10-13
Applicant: David W. Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
Inventor： David W. Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
CPC classification number: A61F2/3094 , A61F2/30 , A61L27/16 , B29C47/0021 , B29C47/54 , B29C47/8805 , B29C55/30 , B29C2035/085 , B29K2023/0683 , B29K2105/25 , C08F110/02 , C08L23/06 , C08F2500/01 , C08F2500/11
Abstract: Solid-state deformation processing of crosslinked high molecular weight polymers such as UHMWPE, for example by extrusion below the melt transition, produces materials with a combination of high tensile strength and high oxidative stability. The materials are especially suitable for use as bearing components in artificial hip and other implants. Treated bulk materials are anisotropic, with enhanced strength oriented along the axial direction. The material is oxidatively stable even after four weeks of accelerated aging in a pressure vessel containing five atmospheres of oxygen (ASTM F2003). Because of its oxidative stability, the deformation processed material is a suitable candidate for air-permeable packaging and gas sterilization, which has thus far been reserved for remelted crosslinked UHMWPE.
Abstract translation: 交联的高分子量聚合物如UHMWPE的固态变形处理例如通过在熔融转变以下挤出产生具有高拉伸强度和高氧化稳定性的组合的材料。 这些材料特别适用于人造髋关节和其他植入物中的轴承部件。 处理的散装材料是各向异性的，其强度沿轴向方向取向。 即使在含有五个大气压的氧气的压力容器中，即使加速老化四周后，材料也是氧化稳定的（ASTM F2003）。 由于其氧化稳定性，变形处理材料是透气包装和气体灭菌的合适的候选者，迄今为止，这已经被保留用于再熔交联的UHMWPE。
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Patent Agency Ranking
公开(公告)号：US4896782A
公开(公告)日：1990-01-30
申请号：US309175
申请日：1989-02-13
Applicant: H. Gene Hawkins , Randall K. Julian , Gary V. Montgomery
Inventor： H. Gene Hawkins , Randall K. Julian , Gary V. Montgomery
CPC classification number: B65D51/18 , B65D41/0442 , B65D2251/0015 , B65D2251/0075
Abstract: A closure having an insert which acts as a barrier over a container neck lip to selectively shield the product being packaged. An elastic sealing member which can be in the form of an O-ring is compressed between the insert and the container neck lip by a threaded cap of the container.
Abstract translation: 具有插入件的封闭件，其用作在容器颈部唇缘上的屏障，以选择性地屏蔽待包装的产品。 可以是O型圈形式的弹性密封构件通过容器的螺纹盖在插入件和容器颈部唇部之间被压缩。
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公开(公告)号：US4844273A
公开(公告)日：1989-07-04
申请号：US240630
申请日：1988-09-06
Applicant: H. Gene Hawkins
Inventor： H. Gene Hawkins
IPC: B65D41/04
CPC classification number: B65D41/0442 , B65D41/0414
Abstract: A closure having an enhanced seal for withstanding distortion of the closure and the container to which it is attached during sterilization.An inner plug cooperates with an outer bead to capture the container neck lip and maintain a separate resilient hermetic seal in position between the closure top and the container neck lip.
Abstract translation: 具有增强的密封件的封闭件，用于在灭菌期间保持封闭物和与其连接的容器的变形。 内部塞子与外部珠子配合以捕获容器颈部唇缘并且在封闭顶部和容器颈部唇缘之间保持分开的弹性密封件的位置。
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8.发明授权公开(公告)号：US08398913B2
公开(公告)日：2013-03-19
申请号：US13185056
申请日：2011-07-18
Applicant: David W. Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
Inventor： David W. Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
CPC classification number: A61F2/3094 , A61F2/30 , A61L27/16 , B29C47/0021 , B29C47/54 , B29C47/8805 , B29C55/30 , B29C2035/085 , B29K2023/0683 , B29K2105/25 , C08F110/02 , C08L23/06 , C08F2500/01 , C08F2500/11
Abstract: Solid-state deformation processing of crosslinked high molecular weight polymers such as UHMWPE, for example by extrusion below the melt transition, produces materials with a combination of high tensile strength and high oxidative stability. The materials are especially suitable for use as bearing components in artificial hip and other implants. Treated bulk materials are anisotropic, with enhanced strength oriented along the axial direction. The material is oxidatively stable even after four weeks of accelerated aging in a pressure vessel containing five atmospheres of oxygen (ASTM F2003). Because of its oxidative stability, the deformation processed material is a suitable candidate for air-permeable packaging and gas sterilization, which has thus far been reserved for remelted crosslinked UHMWPE.
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9.发明申请CROSSLINKED POLYMERIC MATERIAL WITH ENHANCED STRENGTH AND PROCESS FOR MANUFACTURING 有权具有增强强度的交联聚合材料和制造工艺公开(公告)号：US20100298945A1
公开(公告)日：2010-11-25
申请号：US12849640
申请日：2010-08-03
Applicant: David W. Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
Inventor： David W. Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
CPC classification number: C08J3/24 , A61F2/3094 , A61F2/34 , A61L27/16 , B29C47/0016 , B29C47/003 , B29C47/884 , B29C55/30 , B29K2023/0683 , B29K2623/0683 , B29L2031/7532 , C08J2323/06 , C08L23/06
Abstract: A radiation crosslinked (50 kGy), pressure-treated UHMWPE material has been developed by applying compressive force on a crosslinked polymer in a direction orthogonal to an axial direction. The deformed material is then cooled while held in a deformed state. The resulting material is anisotropic, with enhanced strength oriented along the axial direction. The directionally engineered material is oxidatively stable even after four weeks of accelerated aging in a pressure vessel containing five atmospheres of oxygen (ASTM F2003). Because of its oxidative stability, the deformation processed material is a suitable candidate for air-permeable packaging and gas sterilization, which has thus far been reserved for remelted highly crosslinked UHMWPEs.
Abstract translation: 已经通过在与轴向正交的方向上对交联聚合物施加压缩力来开发经辐射交联（50kGy）的经加压处理的UHMWPE材料。 然后将变形的材料冷却，同时保持在变形状态。 所得到的材料是各向异性的，具有沿轴向取向的增强强度。 即使在含有五个大气压的氧气的压力容器（ASTM F2003）中，即使在加速老化四周之后，定向工程材料也是氧化稳定的。 由于其氧化稳定性，变形处理材料是透气包装和气体灭菌的合适的候选物，迄今为止，这已经被保留用于重熔的高度交联的UHMWPE。
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10.发明授权Crosslinked polymeric material with enhanced strength and process for manufacturing 失效具有增强强度的交联聚合物材料和制造方法公开(公告)号：US07462318B2
公开(公告)日：2008-12-09
申请号：US10963975
申请日：2004-10-13
Applicant: David W. Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
Inventor： David W. Schroeder , Jordan H. Freedman , James E. Gunter , Brian D. Salyer , H. Gene Hawkins
CPC classification number: C08J3/24 , A61F2/3094 , A61F2/34 , A61L27/16 , B29C47/0016 , B29C47/003 , B29C47/884 , B29C55/30 , B29K2023/0683 , B29K2623/0683 , B29L2031/7532 , C08J2323/06 , C08L23/06
Abstract: A radiation crosslinked (50 kGy), pressure-treated UHMWPE material has been developed by applying compressive force on a crosslinked polymer in a direction orthogonal to an axial direction. The deformed material is then cooled while held in a deformed state. The resulting material is anisotropic, with enhanced strength oriented along the axial direction. The directionally engineered material is oxidatively stable even after four weeks of accelerated aging in a pressure vessel containing five atmospheres of oxygen (ASTM F2003). Because of its oxidative stability, the deformation processed material is a suitable candidate for air-permeable packaging and gas sterilization, which has thus far been reserved for remelted highly crosslinked UHMWPEs.
Abstract translation: 已经通过在与轴向正交的方向上对交联聚合物施加压缩力来开发经辐射交联（50kGy）的经加压处理的UHMWPE材料。 然后将变形的材料冷却，同时保持在变形状态。 所得到的材料是各向异性的，具有沿轴向取向的增强强度。 即使在含有五个大气压的氧气的压力容器（ASTM F2003）中，即使在加速老化四周之后，定向工程材料也是氧化稳定的。 由于其氧化稳定性，变形处理材料是透气包装和气体灭菌的合适的候选物，迄今为止，这已经被保留用于重熔的高度交联的UHMWPE。
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