摘要:
A device forming a manometer, configured to measure pressure of a biphasic fluid in a fluidic network, including: a first channel inside which a biphasic fluid is able to flow; a second channel emerging into the first channel, wherein the second channel is blind, with each of its dimensions less than capillary length of the fluid's liquid phase, and with at least one of its lengthways wall having a surface energy gradient that decreases from its inlet to the end. The surface energy gradient enables the wetting angle of the meniscus of the fluid's liquid phase to be increased in the blind channel from its inlet to the end. Such a device may find application to measurement of pressure of a biphasic fluid in a heat exchanger or in a fuel cell.
摘要:
The invention provides kits developed to analyze ex vivo, a sample retrieved from the area of the pathological condition for diagnosis and monitoring the pain generator(s) of axial pain with or without radiculopathy and methods for screening therapeutic compounds potentially useful for treating axial pain with or without radiculopathy. Alternatively, degenerated discs can be monitored and treated before occurrence of a pathological pain condition. Pain markers and markers of degenerating disc include markers of neuronal, vascular, immune and matrix elements.
摘要:
A heat exchange device with convective and confined boiling includes a channel in a substrate in contact with an element to be cooled, in which a polar fluid flows from upstream to downstream, a mechanism of movement of the fluid by convection in the channel imposing a direction of flow, and a device for movement by electro-wetting positioned between the channel and the element to be cooled to move the fluid in the channel. The channel includes an inner surface having low wettability with regard to the polar fluid. The mechanism of movement by electro-wetting includes electrodes and a controller to apply selectively a potential to the electrodes such that an electrostatic force gradient is applied to the fluid in the direction of flow.
摘要:
A method for heat exchange by boiling a polar liquid on a surface including at least one low-wetting zone, including: a) generating appearance of nuclei of vapor bubbles on the low-wetting zone, and causing the nuclei to grow; and b) making the surface wetting by at least one electro-wetting system, to favor detachment of the gas bubbles formed in this manner.
摘要:
A heat exchange device including a first surface configured to be in contact with a source of heat to be discharged and a second surface configured to be in contact with a coolant. The device includes a plurality of recesses fluidically insulated from one another, each recess leading onto the second surface via at least one channel, each channel having a length and a transverse size that prevents the coolant from entering the recess. The second surface has better wettability properties with respect to the coolant and the inner surfaces of the channels and the recesses have wettability properties less than or equal to those of the second surface.
摘要:
A motion-preserving implant device for insertion between two bones is disclosed. The motion-preserving implant includes a first plate for engaging with a first bone and a second plate for engaging with a second bone. An articulation member is positioned between the two plates and a motion-controlling member attached to one or both of the plates. In some embodiments, the motion-controlling member is configured to constrain, dampen, and/or bumper the relative motion between the two plates.
摘要:
Systems and methods for repairing annulus defects include at least one blocking member positionable in or adjacent to the annulus defect, and at least one anchor for securing the blocking member to adjacent tissue recessed into the adjacent vertebrae. The blocking member extends at least partially across the annulus defect for repair of the defect and/or retention of nucleus material, one or more implants, bio-compatible materials or device, and/or other objects positioned in the disc space. Instruments are provided to facilitate preparation of the implantation site of the annulus repair system
摘要:
The instant invention discloses novel methods of treating vertebrae, intervertebral discs, and facet joints by administering to these areas or to the implants in these areas a flowable composition comprising an organic material capable of being cured or polymerized in vivo.
摘要:
Allogenic or xenogenic materials are used to provide intervertebral disc nucleus implants and/or annular plugs. The allogenic or xenogenic materials comprise natural disc annulus material, which may have a portion of the anterior longitudinal ligament attached. The tissue may be used “as is” without an additional core or covering, or it may be used in combination with other materials. The material may be rolled, folded, layered and/or sutured, stapled, or glued to provide a solid plug of natural biological material. The implant may be provided as a dehydrated, substantially rod-shaped segment having a diameter less than the diameter of the hydrated material, and may have one or more ends of the dehydrated rod terminate with a further reduced diameter portion, preferably a point.
摘要:
An intervertebral prosthetic disc is disclosed and can be installed within an intervertebral space between a superior vertebra and an inferior vertebra. The intervertebral prosthetic disc can include an inferior component that can have a depression formed therein and a superior component that can have a projection extending therefrom. The projection can be configured to movably engage the depression and allow relative motion between the inferior component and the superior component. Further, the projection can include a superior wear resistant layer that can have a cross-linked polymer and can be configured to engage the depression.