公开(公告)号：US20070179316A1

公开(公告)日：2007-08-02

申请号：US11657147

申请日：2007-01-24

申请人： Fritz Pohl ,  Jeffrey Bolton ,  Richard Adamson ,  Heinz-Herbert Muller ,  Rudolf Uchdorf

发明人： Fritz Pohl ,  Jeffrey Bolton ,  Richard Adamson ,  Heinz-Herbert Muller ,  Rudolf Uchdorf

IPC分类号： C07C209/24

CPC分类号： C07C209/78 ,  C07C211/50

摘要： The invention provides an improved process for preparing diamines and polyamines from the diphenylmethane series by reacting aniline and formaldehyde in the presence of an acid catalyst, the improvement involving the aniline containing less than about 3 wt. % of diamines and polyamines from the diphenylmethane series, based on the weight of the aniline.

摘要翻译： 本发明提供了一种通过在酸催化剂存在下使苯胺和甲醛反应从二苯基甲烷系列制备二胺和多胺的改进方法，涉及含有小于约3wt。 基于苯胺的重量，来自二苯基甲烷系列的二胺和多胺的百分比。

公开(公告)号：US20050064596A1

公开(公告)日：2005-03-24

申请号：US10475967

申请日：2002-04-23

申请人： Gudula Riemen ,  Elke Lorbach ,  Juliana Helfrich ,  Gregor Siebenkotten ,  Herbert Muller-Hartmann ,  Kirsten Rothmann-Cosic ,  Corinna Thiel ,  Meike Weigel ,  Heike Wessendorf ,  Helmut Brosterbus ,  Michael Nix

发明人： Gudula Riemen ,  Elke Lorbach ,  Juliana Helfrich ,  Gregor Siebenkotten ,  Herbert Muller-Hartmann ,  Kirsten Rothmann-Cosic ,  Corinna Thiel ,  Meike Weigel ,  Heike Wessendorf ,  Helmut Brosterbus ,  Michael Nix

IPC分类号： C12N15/09 ,  A61K35/12 ,  A61K38/00 ,  A61K47/00 ,  A61K48/00 ,  C12N13/00 ,  C12N15/87 ,  G01N33/50

CPC分类号： C12N15/87 ,  A61K38/00 ,  A61K48/00

摘要： The invention relates to a buffer solution for suspending animal or human cells and for dissolving biologically active molecules in order to introduce said biologically active molecules into the cells using an electric current and to a method for introducing biologically active molecules into animal or human cells using an electric current and a buffer solution. The inventive buffer solution has a buffering capacity of at least 20 mmol*I−1*pH−1 and an ionic strength of at least 200 mmol*I−1 during a change to the pH value from pH 7 to pH 8 and at a temperature of 25° C. The use of a buffer solution of this type in the corresponding method allows biologically active molecules to be introduced into animal and human cells with a high degree of transfection efficiency and at the same time a low cell mortality. Different cell types, in particular dormant and actively dividing cells of low activity, can be successfully transfected in said buffer solution.

摘要翻译： 本发明涉及一种用于悬浮动物或人细胞并用于溶解生物活性分子以便使用电流将所述生物活性分子引入细胞的缓冲溶液以及使用以下方法将生物活性分子引入动物或人细胞的方法： 电流和缓冲液。 本发明的缓冲溶液在pH值从pH7变化期间具有至少20mmol * I -1 * pH <-1的缓冲能力和至少200mmol * I -1的离子强度 至pH8，温度为25℃。在相应方法中使用这种类型的缓冲溶液使生物活性分子以高度的转染效率被引入动物和人类细胞，并且同时 细胞死亡率低。 可以在所述缓冲溶液中成功转染不同细胞类型，特别是低活性的休眠和活跃分化细胞。

公开(公告)号：US20050028648A1

公开(公告)日：2005-02-10

申请号：US10489081

申请日：2002-09-05

申请人： Werner Lutz ,  Herbert Muller

发明人： Werner Lutz ,  Herbert Muller

IPC分类号： B23P19/06 ,  B25B13/50

CPC分类号： B23P19/069 ,  Y10T29/534 ,  Y10T29/53417 ,  Y10T483/1738

摘要： A screwing station, in particular along an assembly line, comprises at least one machine frame and a screwing tool adjustably supported relative thereto between at least one retracted and one operative position and connected to a supply and, optionally, a measuring line. To improve a screwing station of this type in such a way that less mass has to be moved while the screwing station is of a simple construction, so that wear, maintenance work and energy consumption are reduced and a concurrent movement of supply and measuring lines is prevented at the same time, which might otherwise result in damage to the lines, the screwing tool comprises a drive shaft supported on the machine frame and a wrench head telescopically displaceable relative to said shaft, the drive shaft and wrench head being drivingly connected and the wrench head being movable by means of a lifting and lowering means between retracted and operative position.

摘要翻译： 螺旋工位，特别是沿着装配线，包括至少一个机架和一个在至少一个缩回和一个操作位置之间相对于其可调节地支承的连接到电源和可选的测量线的螺丝拧紧工具。 为了改善这种类型的旋转站，在旋转站结构简单的同时，必须移动较少的质量，从而减少磨损，维护工作和能量消耗，并且供应和测量线路的同时运动是 同时防止这可能导致线路的损坏，螺丝刀包括支撑在机架上的驱动轴和相对于所述轴可伸缩移位的扳手头，驱动轴和扳手头被驱动连接，并且 扳手头可通过在缩回和操作位置之间的提升和降低装置移动。

公开(公告)号：US20050003553A1

公开(公告)日：2005-01-06

申请号：US10845727

申请日：2004-05-14

申请人： Jochen Mahrenholtz ,  Andrea Wimschneider ,  Hans-Georg Pirkl ,  Heinz-Herbert Muller ,  Stefan Dresely ,  Jeffrey Bolton ,  Martin Schiffhauer ,  Gdo Wolf ,  Johannes Schweer ,  Martin Gerlach

发明人： Jochen Mahrenholtz ,  Andrea Wimschneider ,  Hans-Georg Pirkl ,  Heinz-Herbert Muller ,  Stefan Dresely ,  Jeffrey Bolton ,  Martin Schiffhauer ,  Gdo Wolf ,  Johannes Schweer ,  Martin Gerlach

IPC分类号： C07C265/00 ,  C07C263/20 ,  C07C265/14 ,  G01J3/433 ,  G01N21/25 ,  G01N21/35 ,  G01N21/65 ,  G01N33/00

CPC分类号： G01N21/359 ,  G01J3/433 ,  G01N21/3577 ,  G01N21/65 ,  G01N2021/8416 ,  G01N2201/1293 ,  Y10T436/12 ,  Y10T436/17 ,  Y10T436/172307

摘要： The invention relates to a method for determining the isomer composition in an isocyanate isomer mixture, wherein a spectrum of the isomer mixture is recorded and the spectrum is entered into a chemometric calibration model.

摘要翻译： 本发明涉及一种用于测定异氰酸酯异构体混合物中的异构体组合物的方法，其中记录异构体混合物的光谱，并将光谱输入到化学计量校准模型中。

公开(公告)号：US5988560A

公开(公告)日：1999-11-23

申请号：US110246

申请日：1998-07-06

申请人： Joachim Hinz ,  Herbert Muller

发明人： Joachim Hinz ,  Herbert Muller

IPC分类号： B65H18/02 ,  B65H18/20 ,  B65H18/26

CPC分类号： B65H18/26 ,  B65H18/02 ,  B65H18/20 ,  B65H2301/414866 ,  B65H2406/13 ,  B65H2406/131 ,  B65H2408/2321

摘要： Roll winding device and process for use, e.g., in a reel slitting device. The roll winding device includes a roll carrier device, a pneumatic pressure release device including a plurality of blow boxes having top sides with escape nozzles, and a rocker arm on which the blow boxes are mounted in articulated pairs. The blow boxes are swivelably adjustable on tilting axes that run parallel to a roll axis. The process includes positioning the blow boxes beneath a peripheral surface of a roll being wound on the winding machine and ejecting air through the escape nozzles in the blow boxes directed toward the peripheral surface to orient the top surface of the blow box substantially parallel to a tangent of the peripheral surface and to position the top surfaces of the blow boxes a substantially same distance from the peripheral surface. In this manner, the ejected air forms an air cushion under the roll.

摘要翻译： 卷绕装置和使用的方法，例如在卷筒切割装置中。 卷筒卷绕装置包括卷筒托架装置，气动压力释放装置，其包括多个具有带有逸出喷嘴的顶面的吹风箱和摇臂，吹风箱以铰接对安装在该摇臂上。 吹风箱可以在平行于轧辊轴线的倾斜轴上进行可旋转调节。 该方法包括将吹风箱定位在卷绕在卷绕机上的辊的外周表面下方，并将空气通过指向周边表面的吹风箱中的逸出喷嘴排出，以使吹风箱的顶表面基本上平行于切线 并且使吹风箱的顶表面与外围表面基本相同的距离。 以这种方式，排出的空气在辊下形成气垫。

公开(公告)号：US5784969A

公开(公告)日：1998-07-28

申请号：US765762

申请日：1997-06-18

申请人： Siegbert Steidl ,  Gunter Wagner ,  Clemens Jungkunz ,  Herbert Muller ,  Bernhard Rath ,  Anton Stribersky ,  Peter Drucke ,  Werner Niemeyer-Stein

发明人： Siegbert Steidl ,  Gunter Wagner ,  Clemens Jungkunz ,  Herbert Muller ,  Bernhard Rath ,  Anton Stribersky ,  Peter Drucke ,  Werner Niemeyer-Stein

IPC分类号： B61F5/22 ,  G05D1/08 ,  B61F5/24

CPC分类号： B61F5/22 ,  G05D1/0891

摘要： A process and device for controlling the inclination of rail vehicle boxes in a railway vehicle, the rail vehicle boxes sitting on spring-suspended bogies with at least one pair of wheels which can be pivoted about the longitudinal axis. The centrifugal acceleration in the horizontal plane is determined and a setpoint is calculated for the absolute inclination of the box relative to the earth. An actual value of the absolute inclination of the box relative to the earth is determined and at least one control signal is formed from the difference between the setpoint and the actual value of the absolute inclination of the box. The angle between the bogie and the box is adjusted across the direction of travel as a function of the control signal thus formed. This makes it possible to control the inclination of the box independently of the type of track banking design and any possible interference.

摘要翻译： PCT No.PCT / EP95 / 02548 Sec。 371日期：1997年6月18日 102（e）日期1997年6月18日PCT提交1995年6月30日PCT公布。 出版物WO96 / 02027 日期1996年1月25日一种用于控制铁路车辆中的铁路车辆箱的倾斜的过程和装置，轨道车厢坐在弹簧悬挂的转向架上，具有至少一对可绕纵向轴线枢转的车轮。 确定水平面的离心加速度，并计算箱体相对于地球的绝对倾角的设定点。 确定盒子相对于地球的绝对倾斜度的实际值，并根据设定值与盒子的绝对倾斜度的实际值之间的差异形成至少一个控制信号。 作为由此形成的控制信号的函数，转向架和箱体之间的角度在行进方向上被调节。 这使得可以独立于轨道银行设计的类型和任何可能的干扰来控制盒的倾斜度。

公开(公告)号：US5092755A

公开(公告)日：1992-03-03

申请号：US660209

申请日：1991-02-22

申请人： Roland Pfulb ,  Herbert Muller

发明人： Roland Pfulb ,  Herbert Muller

IPC分类号： B29C69/00

CPC分类号： B29C47/0066 ,  B29C2793/0063 ,  B29C47/0019 ,  B29C47/003

摘要： plurality of synthetic-resin strands are made in a nozzle having a housing forming a passage having an upstream end and a downstream end. The downstream end is formed as an elongated slot having a relatively great length and a relatively short width measured perpendicular to its length. An extruder connected to the housing at the upstream end of the passage introduces a fluent thermoplastic synthetic resin thereinto under pressure so the resin exits from the slot in a predetermined flow direction. A plurality of blades are retained in holders on the nozzle immediately downstream of the downstream of the passage at the slot with each blade traversing the slot crosswise of its length. Thus the resin exiting from the slot is cut by the blades into the strands. The holders are adjustable along the slot for horizontally displacing and fixing the blades so as to vary the dimensions of the strands.

摘要翻译： 在具有形成具有上游端和下游端的通道的壳体的喷嘴中制造多个合成树脂股线。 下游端形成为具有相对较长的长度并且垂直于其长度测量的相对较短宽度的细长槽。 在通道的上游端连接到壳体的挤出机在压力下引入流动的热塑性合成树脂，使得树脂在预定的流动方向上从槽中排出。 多个叶片被保持在喷嘴上的保持器中，紧靠在槽的下游的下游，每个叶片横过槽的长度。 因此，从槽口出来的树脂被刀片切割成股线。 保持器可沿着槽调节，用于水平移位和固定刀片，以便改变线的尺寸。

公开(公告)号：US4902865A

公开(公告)日：1990-02-20

申请号：US273755

申请日：1988-11-16

申请人： Herbert Muller ,  Gerhardt Sehnke

发明人： Herbert Muller ,  Gerhardt Sehnke

IPC分类号： H01H3/02

CPC分类号： H01H3/022 ,  H01H2003/024

摘要： The invention relates to a push-pull actuator for key switches with a mushroom knob (1) which is loaded by a restoring force and is supported longitudinally movable. This mushroom knob (1) is separated from the actuating plunger. This actuating plunger is spring-loaded in the switching direction and is locked in the operating position by rocker levers (13). The locking is cancelled by a relative motion between the mushroom knob (1) and the actuating plunger (6) by the sliding of inclined surfaces (23) at the edges of the rocker levers (13) so that the actuating plunger is moved into the off position by the spring (20). In the off position, the rocker levers (13) with the back sides (19) are brought into engagement with the end faces (18) of the rocker levers.

摘要翻译： 本发明涉及一种具有伞形旋钮（1）的钥匙开关的推拉式致动器，其通过恢复力加载并被纵向移动。 该蘑菇钮（1）与致动柱塞分离。 该致动柱塞在切换方向上弹簧加载，并通过摇杆（13）锁定在操作位置。 通过在摇臂（13）的边缘处的倾斜表面（23）的滑动，通过伞形把手（1）和致动柱塞（6）之间的相对运动来消除锁定，使得致动柱塞移动到 关闭位置（20）。 在关闭位置，具有后侧（19）的摇杆（13）与摇臂的端面（18）接合。

公开(公告)号：US4131352A

公开(公告)日：1978-12-26

申请号：US801386

申请日：1977-05-27

申请人： Gunter Fauth ,  Herbert Muller

发明人： Gunter Fauth ,  Herbert Muller

IPC分类号： G03B17/52 ,  G03B17/50

CPC分类号： G03B17/52

摘要： An improved pressure roller in a photographic apparatus of the self-developing type is disclosed. The roller has a rigid core provided with two axially spaced circumferential grooves which are filled with resiliently compressible material. The core is jacketed with a resilient sheath which covers its circumferential surface, including the grooves and the material therein.

摘要翻译： 公开了一种改进的自显影照相装置中的压力辊。 辊具有设置有两个轴向隔开的周向槽的刚性芯，其填充有可弹性压缩的材料。 芯部具有覆盖其圆周表面的弹性护套，包括槽和其中的材料。

公开(公告)号：US4001942A

公开(公告)日：1977-01-11

申请号：US582417

申请日：1975-05-29

申请人： Fritz Schuermann ,  Herbert Muller ,  Horst Boddicker

发明人： Fritz Schuermann ,  Herbert Muller ,  Horst Boddicker

IPC分类号： E21F17/18 ,  G01B5/14 ,  G01B5/30 ,  G01B5/00

CPC分类号： E21F17/185 ,  G01B5/14 ,  G01B5/30

摘要： A rod extensometer which can be inserted into a hole drilled into the roof or floor of an underground excavation to monitor the shifting of material surrounding the excavation. The extensometer has a head which is anchored in the inner end portion of the hole by a hardened synthetic plastic substance, an annular section which is inserted into the outer end portion of the hole and is bonded to surrounding material, and a set of interconnected coaxial cylindrical rods one of which is rigid with the head and another of which extends through the annular section. Changes in distance between the outer end of the other rod and the annular section are indicative of movement of material surrounding the inner end portion of the hole relative to material surrounding the outer end portion of the hole and/or vice versa. The head has an externally threaded member which is bonded to the surrounding material and a blade-like or conical breaker member located forwardly of the externally threaded member and serving to break a cartridge which contains separate supplies of a hardenable synthetic plastic bonding substance and a hardening agent for such substance. The annular section of the extensometer has a nut and washer which abuts against the exposed surface of material bounding the outer end portion of the hole, and the outer end of the other rod has flats which can be engaged by a torque transmitting device serving to rotate the rods and the head. Two identical or dissimilar extensometers can be installed in two coaxial holes to facilitate additional measurements, such as changes in the distance between the two heads, changes in the distance between the two nuts, as well as changes in the distance between each head and the respective nut.

摘要翻译： 杆伸长计可以插入到钻进地下开挖屋顶或地板的孔中，以监测围绕挖掘的材料的移动。 引伸计具有通过硬化的合成塑料物质锚固在孔的内端部的头部，插入到孔的外端部并与周围材料接合的环形部分，以及一组互连的同轴 圆柱形杆，其中一个与头部刚性，另一个延伸穿过环形部分。 另一个杆的外端与环形部分之间的距离的变化表示围绕孔的内端部的材料相对于围绕孔的外端部的材料的运动和/或反之亦然。 头部具有外部螺纹构件，其结合到周围材料和位于外螺纹构件前方的刀片状或锥形的断屑器构件，并且用于破坏包含可硬化的合成塑料粘合物质的单独供应的筒和硬化 这种物质的代理。 引伸计的环形部分具有螺母和垫圈，该螺母和垫圈抵靠围绕孔的外端部分的材料的暴露表面，另一个杆的外端具有平面，该平面可以由用于旋转的扭矩传递装置 杆和头。 两个相同的或不同的引伸计可以安装在两个同轴孔中，以便于附加的测量，例如两个头之间的距离的变化，两个螺母之间的距离的变化，以及每个头与相应的距离之间的距离的变化 坚果。