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公开(公告)号：US20110236360A1
公开(公告)日：2011-09-29
申请号：US13119382
申请日：2009-09-29
申请人： Daisuke Ochi , Hiroshi Tsuboi
发明人： Daisuke Ochi , Hiroshi Tsuboi
CPC分类号： A61K35/74 , A23L33/135 , A23V2002/00 , A23Y2220/37 , C12R1/225 , A23V2200/306
摘要： The present invention provides lactic acid bacteria having oxalic acid-degrading activity several times higher than those of conventionally known lactic acid bacteria having an oxalic acid-degrading activity, and uses thereof. Lactic acid bacteria capable of degrading a large amount of oxalic acid were screened from 132 strains of Lactobacillus lactic acid bacteria that have been independently isolated from feces and gastric juices of human adults. As a result, lactic acid bacteria having an oxalic acid degradation rate of 50% or more when cultured at 37° C. for 72 hours in a culture medium containing 10 mM oxalic acid at pH 6.5 at the start of culture were discovered.
摘要翻译： 本发明提供了具有比常规已知的具有草酸降解活性的乳酸菌高几倍的草酸降解活性的乳酸菌及其用途。 从132个来自人类粪便和胃液中独立分离的乳酸杆菌乳杆菌筛选能够降解大量草酸的乳酸菌。 结果发现，培养开始时，在含有10mM草酸的培养基中，在37℃培养72小时，草酸降解率为50％以上的乳酸菌。
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公开(公告)号：US09283252B2
公开(公告)日：2016-03-15
申请号：US13119382
申请日：2009-09-29
申请人： Daisuke Ochi , Hiroshi Tsuboi
发明人： Daisuke Ochi , Hiroshi Tsuboi
CPC分类号： A61K35/74 , A23L33/135 , A23V2002/00 , A23Y2220/37 , C12R1/225 , A23V2200/306
摘要： The present invention provides lactic acid bacteria having oxalic acid-degrading activity several times higher than those of conventionally known lactic acid bacteria having an oxalic acid-degrading activity, and uses thereof. Lactic acid bacteria capable of degrading a large amount of oxalic acid were screened from 132 strains of Lactobacillus lactic acid bacteria that have been independently isolated from feces and gastric juices of human adults. As a result, lactic acid bacteria having an oxalic acid degradation rate of 50% or more when cultured at 37° C. for 72 hours in a culture medium containing 10 mM oxalic acid at pH 6.5 at the start of culture were discovered.
摘要翻译： 本发明提供了具有比常规已知的具有草酸降解活性的乳酸菌高几倍的草酸降解活性的乳酸菌及其用途。 从132个来自人类粪便和胃液中独立分离的乳酸杆菌乳杆菌筛选能够降解大量草酸的乳酸菌。 结果发现，培养开始时，在含有10mM草酸的培养基中，在37℃培养72小时，草酸降解率为50％以上的乳酸菌。
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3.发明授权公开(公告)号：US08612057B2
公开(公告)日：2013-12-17
申请号：US12809251
申请日：2008-12-17
申请人： Kensuke Murata , Masayuki Nagaishi , Katsuhisa Tsuchiya , Shoichi Tsuiki , Masami Tsujita , Hiroshi Tsuboi
发明人： Kensuke Murata , Masayuki Nagaishi , Katsuhisa Tsuchiya , Shoichi Tsuiki , Masami Tsujita , Hiroshi Tsuboi
摘要： A water discharge system capable of preventing a mistaken detection to surely perform the stop of water discharge or continue the start of water discharge is provided. The water discharge system includes: a water discharge unit; a sensor unit configured to obtain information about an object to be detected through a reflected wave of a radiated radio wave; a control unit configured to control the start of water discharge from the water discharge unit based on a detective signal from the sensor unit; and a storage mechanics. The sensor unit is installed so that at least part of a radiated radio wave comes into contact with a discharged water flow discharged from the water discharge unit and receives the reflected wave reflected by the discharged water flow, and the control unit determines a state of the discharged water flow by checking a relationship between a first threshold set larger than amplitude of oscillation around a reference value of the detective signal in a water flow state in which only the start of water discharge from the water discharge unit is performed and amplitude of the detective signal received by the sensor unit.
摘要翻译： 提供了能够防止错误检测以确定地执行排水停止或继续开始排水的排水系统。 排水系统包括：排水单元; 传感器单元，被配置为通过辐射无线电波的反射波获得关于要检测的对象的信息; 控制单元，被配置为基于来自所述传感器单元的检测信号来控制从所述排水单元开始排水; 和存储机制。 传感器单元被安装成使得辐射无线电波的至少一部分与从排水单元排出的排出水流接触并接收由排出水流反射的反射波，并且控制单元确定 通过检查在仅执行来自排水单元的排水开始的水流状态下的检测信号的基准值周围的振荡振幅周围的第一阈值与检测器的振幅之间的关系， 信号由传感器单元接收。
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公开(公告)号：US20100316618A1
公开(公告)日：2010-12-16
申请号：US12745006
申请日：2008-11-27
申请人： Hiroshi Tsuboi , Noriko Kaneko , Akina Satou , Akinori Kume , katsunori Kimura
发明人： Hiroshi Tsuboi , Noriko Kaneko , Akina Satou , Akinori Kume , katsunori Kimura
CPC分类号： C12R1/225 , A23C9/1234 , A23L33/135 , A23Y2220/37 , A61K35/747
摘要： The present invention provides lactic acid bacteria which are suitable for use for dietary products and pharmaceuticals, and which can suppress the increase of blood uric acid level.Various types of lactic acid bacteria were cultured in the presence of a purine, the amount of the purine consumed and the amount of purine degradation products produced were measured, and several lactic acid bacteria showing remarkable purine-decomposing ability were selected. Lactic acid bacteria that were assessed to have high purine-decomposing ability according to the above-mentioned selection were orally administered to rats reared on purine-containing feed, the general status and serum uric acid level of the rats were measured, and the effect of lactic acid bacteria administration on serum uric acid levels was examined. As a result, lactic acid bacteria that significantly suppress the increase of serum uric acid levels, Lactobacillus gasseri OLL2922, were found.
摘要翻译： 本发明提供适用于饮食品和药物的乳酸菌，可抑制血液中尿酸水平的升高。 在嘌呤存在下培养各种类型的乳酸菌，测定嘌呤消耗量和产生的嘌呤降解产物量，选择显示出显着的嘌呤分解能力的几种乳酸菌。 对含有嘌呤的饲料饲养的大鼠口服给予根据上述选择被评估为具有高嘌呤分解能力的乳酸菌，测定大鼠的一般状态和血清尿酸水平， 检测乳酸菌对血清尿酸水平的影响。 结果发现，显着抑制血清尿酸水平升高的乳酸菌，加氏乳杆菌（Lactobacillus gasseri）OLL2922。
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公开(公告)号：US6113378A
公开(公告)日：2000-09-05
申请号：US862703
申请日：1997-05-23
申请人： Hiroshi Tsuboi , Toshinori Okamoto , Kunio Kojima
发明人： Hiroshi Tsuboi , Toshinori Okamoto , Kunio Kojima
CPC分类号： B30B11/04 , B30B11/027
摘要： A mold for molding a drum shaped magnetic core having two flanges connected by a coil winding core portion. The mold includes a die defining a cylindrical cavity having an inner diameter substantially equal to an outer diameter of the flanges. A pair of die inserts are movable in an orthogonal direction relative to the cylindrical cavity and define a diameter of the coil winding core portion of the drum shaped magnetic core. The diameter of the coil winding core portion is smaller than the outer diameter of the flanges. An upper punch and a lower punch are inserted into the cylindrical cavity from a corresponding end opening of the mold such that each forms a flange. A central punch is disposed coaxially within one of the punches to form the coil winding core portion.
摘要翻译： 一种用于模制鼓形磁芯的模具，其具有通过线圈绕组芯部分连接的两个凸缘。 模具包括限定具有基本上等于凸缘的外径的内径的圆柱形腔的模具。 一对模插件可以相对于圆柱形空腔在正交方向上移动，并且限定鼓形磁芯的线圈绕组芯部分的直径。 线圈绕芯部分的直径小于凸缘的外径。 上冲头和下冲头从模具的对应的端部开口插入到圆柱形腔中，使得每个形成凸缘。 中心冲头同轴地布置在一个冲头内以形成线圈卷绕芯部分。
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公开(公告)号：US5625911A
公开(公告)日：1997-05-06
申请号：US537760
申请日：1996-01-19
申请人： Chiaki Nakayama , Kuniaki Shinohara , Naoki Sato , Hiroshi Tsuboi
发明人： Chiaki Nakayama , Kuniaki Shinohara , Naoki Sato , Hiroshi Tsuboi
IPC分类号： A47K13/00 , A61B10/00 , E03D9/00 , G01N1/10 , G01N33/483 , G01N33/493 , E03D11/00 , A61B5/00
CPC分类号： G01N33/493 , A61B10/007
摘要： A method and an apparatus (30) for sampling urine at a toilet (10) equipped with a standard water closet bowl fixture (12). An elongated, curved, urine sampling trough (32) having a U-shaped cross-section is used. For sampling of urine, the sampling trough (32) is positioned in the vertical central plane (46) of the toilet bowl fixture in such a manner that it extends obliquely between the upper front region and the bottom region of the inner space of the bowl (14). As the urine sampling trough (32) covers a substantial length in the vertical direction as well as in the fore-and-aft direction, the urine column hits on the sampling trough even when the trajectory of urine column is fluctuated in the vertical or fore-and-aft direction, whereby urine is effectively sampled. As the urine sampling trough is elongated and curved, it can be readily stored under the toilet seat when not in use.
摘要翻译： PCT No.PCT / JP95 / 00259 Sec。 371日期1996年1月19日 102（e）日期1996年1月19日PCT提交1995年2月23日PCT公布。 公开号WO95 / 23337 日期1995年8月31日一种用于在配备有标准洗手间碗具（12）的马桶（10）上抽尿的方法和装置（30）。 使用具有U形横截面的细长弯曲的尿液采样槽（32）。 为了取样尿液，采样槽（32）以这样的方式定位在马桶装置的垂直中心平面（46）中，使其在碗的内部空间的上部前部区域和底部区域之间倾斜地延伸 （14）。 当尿液采样槽（32）在垂直方向和前后方向上覆盖相当长的长度时，即使当尿液柱的轨迹在垂直或前方波动时，尿液塔也会在取样槽上撞击 后方向，从而有效地抽取尿液。 当尿液采样槽细长且弯曲时，可以在不使用时容易地储存在马桶座下。
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7.发明授权Stool-type apparatus for sampling and assay of urine with swingable carriage 失效用于采用可移动运输的尿液取样和测定的STOOL型装置
公开(公告)号：US5184359A
公开(公告)日：1993-02-09
申请号：US748211
申请日：1991-08-22
CPC分类号： A61B5/02241 , A61B10/0051 , A61B10/007
摘要： A toilet system (10) with urine assay function is disclosed which comprises a toilet stool (12) having a toilet bowl (14) and a small urine-sampling cavity (52). A frame (42) is mounted on the toilet stool to support a testing sheet handling and transfer mechanism (30) which comprises a swingable carriage (46) and a slidable arm (50) supported by the carriage for linear telescoping movement. The carriage is swingable about a vertical axis (48) between a first position in which the carriage is oriented toward the sampling cavity and a second position in which the carriage is oriented to a lateral side of the stool wherein a disposal station is provided.The toilet system enables the use of testing sheets (32) which are made from water insoluble materials.Various other embodiments are also disclosed.The system provides a high degree of reliability of analysis.
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公开(公告)号：US20120308539A1
公开(公告)日：2012-12-06
申请号：US13544756
申请日：2012-07-09
申请人： Hiroshi Tsuboi , Noriko Kaneko , Akina Satou , Yoshinobu Tsuchiya
发明人： Hiroshi Tsuboi , Noriko Kaneko , Akina Satou , Yoshinobu Tsuchiya
CPC分类号： A23C9/1234 , A23C9/1238 , A23L33/135 , A23V2002/00 , A23Y2220/61 , A61K35/747 , C12R1/225 , A23V2200/30
摘要： Various types of lactic acid bacteria were cultured in the presence of a purine, the amount of the purine consumed and the amount of purine degradation products produced were measured, and several lactic acid bacteria showing remarkable purine-decomposing ability were selected. Lactic acid bacteria that were assessed to have high purine-decomposing ability according to the above-mentioned selection were orally administered to rats reared on purine-containing feed, the general status and serum uric acid level of the rats were measured, and the effect of lactic acid bacteria administration on serum uric acid levels was examined. As a result, lactic acid bacteria that significantly suppress the increase of serum uric acid levels, Lactobacillus gasseri OLL2959 and Lactobacillus oris OLL2779, were found.
摘要翻译： 在嘌呤存在下培养各种类型的乳酸菌，测定嘌呤消耗量和产生的嘌呤降解产物量，选择显示出显着的嘌呤分解能力的几种乳酸菌。 对含有嘌呤的饲料饲养的大鼠口服给予根据上述选择被评估为具有高嘌呤分解能力的乳酸菌，测定大鼠的一般状态和血清尿酸水平， 检测乳酸菌对血清尿酸水平的影响。 结果发现显着抑制血清尿酸水平升高的乳酸菌，加氏乳杆菌OLL2959和乳酸杆菌OLL2779。
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公开(公告)号：US08171578B2
公开(公告)日：2012-05-08
申请号：US12182990
申请日：2008-07-30
申请人： Masami Tsujita , Tomoyuki Abe , Naoki Kabe , Hiroshi Tsuboi , Masayuki Nagaishi , Katsuhisa Tsuchiya , Shoichi Tsuiki , Kensuke Murata
发明人： Masami Tsujita , Tomoyuki Abe , Naoki Kabe , Hiroshi Tsuboi , Masayuki Nagaishi , Katsuhisa Tsuchiya , Shoichi Tsuiki , Kensuke Murata
IPC分类号： E03C1/05
CPC分类号： E03C1/057 , G01S13/56 , G01S13/582 , G01S13/88
摘要： There is provided a water discharge system. A water discharge system includes a water discharge portion; a sensor unit which acquires movement information about an object based on a radiated electric wave, and outputs a detecting signal; and a control unit which controls water discharge of the water discharge portion based on the detecting signal. When it is detected that the object is decelerated to a first threshold velocity or less, the control unit controls the water discharge portion to start the water discharge.
摘要翻译： 提供排水系统。 排水系统包括排水部分; 传感器单元，其基于辐射电波获取关于对象的移动信息，并输出检测信号; 以及控制单元，其基于检测信号来控制排水部的排水。 当检测到物体减速到第一阈值速度或更小时，控制单元控制排水部分开始排水。
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公开(公告)号：US20080088510A1
公开(公告)日：2008-04-17
申请号：US11664292
申请日：2005-09-29
申请人： Kensuke Murata , Hiroshi Tsuboi , Kengo Iwata , Tomoyuki Abe
发明人： Kensuke Murata , Hiroshi Tsuboi , Kengo Iwata , Tomoyuki Abe
CPC分类号： H01Q3/24 , H01Q9/0407 , H01Q9/0442 , H01Q19/005 , H01Q19/28
摘要： A microstrip antenna has feed element 102 and parasitic elements 104, 106 on the front surface of substrate 1. Microwave electrical power is applied to feed element 102. Parasitic elements 104, 106 are connected via through hole type leads passing through substrate 1, to switches upon the rear surface of substrate 1, respectively. By actuating the switches individually, parasitic elements 104, 106 are individually switched between a grounded state and a float state. The direction of the radio beam emitted from the microstrip antenna is varied by selecting which of parasitic elements 104, 106 is grounded and floated. A microwave signal source connects to feed element 102 via an feed line 108 very much shorter than the wavelength, accordingly the transmission losses being low and the efficiency being excellent.
摘要翻译： 微带天线具有馈电元件102和衬底1的前表面上的寄生元件104,106。 微波电力施加到馈电元件102。 寄生元件104,106通过穿过衬底1的通孔型引线分别连接到衬底1的后表面上。 通过单独地驱动开关，寄生元件104,106在接地状态和浮置状态之间单独切换。 通过选择寄生元件104,106中的哪一个接地并漂浮来改变从微带天线发射的无线电波束的方向。 微波信号源通过比波长短得多的馈线108连接到馈电元件102，因此传输损耗低，效率优异。
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