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公开(公告)号：US10017727B2
公开(公告)日：2018-07-10
申请号：US12085549
申请日：2006-11-28
IPC分类号： A61K36/03 , C12N1/20 , A23G3/48 , A61K36/48 , A61K36/899 , C12P19/04 , A23L33/10 , A23L33/105
CPC分类号： C12N1/20 , A23G3/48 , A23L33/10 , A23L33/105 , A61K36/03 , A61K36/48 , A61K36/899 , C12P19/04
摘要： In order to provide a method for culturing an immunopotentiator-containing organism having the experience of being eaten, inexpensively without requiring usage of a component derived from an animal, Acetobacter, Gluconobacter, Xanthomonas, Zymomonas or Enterobacter which is an edible gram-negative bacterium having an immunopotentiation function is cultured using a culture solution composed mainly of wheat or bean curd refuse. Thereby, Acetobacter can be obtained inexpensively and safely, and also a low molecular weight lipopolysaccharide which is the immunopotentiator can be obtained inexpensively and safely. Furthermore, no impurity derived from animal components is mixed.
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2.发明申请PLANT GROWING AGENT, PLANT DISEASE RESISTANCE INDUCER, AND PLANT DISEASE CONTROL METHOD 审中-公开植物生长剂，植物病害感染和植物病害控制方法公开(公告)号：US20120202692A1
公开(公告)日：2012-08-09
申请号：US13497910
申请日：2010-09-17
申请人： Yohko Nakata , Chie Kohchi , Hiroyuki Inagawa , Gen-Ichiro Soma , Kenji Gomi
发明人： Yohko Nakata , Chie Kohchi , Hiroyuki Inagawa , Gen-Ichiro Soma , Kenji Gomi
摘要： A disease resistance capacity of vegetables, grasses and flowers, etc., is enhanced and their survival rates are improved by growing plants in an appropriate coexistence of a glycolipid derived from Pantoea agglomerans or a composition containing the glycolipid. Thereby, a method of augmenting disease resistance of vegetables, grasses and flowers, etc., and growing agricultural crops with high quality is provided, and further a novel plant growing agent and plant disease resistance inducer that enables this are provided. As a result, it becomes possible to cultivate agricultural crops or increase productivity with as little use of agricultural chemicals as possible. Even if an amount of the agricultural chemical is reduced, a cultivation success rate of agricultural crops can be enhanced and immunity of the plant body can be enhanced even where useful soil bacteria are not frequently present. Thus, new types of agricultural crop businesses such as contract cultivations by means of organic cultivation, agricultural chemical-free cultivation and hydroponic cultivation are promoted.
摘要翻译： 蔬菜，草和花等的抗病能力得到提高，并且通过在衍生自成团泛菌或含有糖脂的组合物的糖脂的合适共存中培育植物来提高其存活率。 因此，提供了提高蔬菜，草，花等的抗病性，高品质生长的农作物的方法，进一步提供了能够实现的新型植物生长剂和植物病害诱导剂。 因此，尽可能少地使用农药可以培育农作物或提高生产率。 即使减少了农药的量，即使不经常存在有用的土壤细菌，也能够提高农作物的种植成功率，能够提高植物体的免疫力。 因此，促进了有机种植，农业无化学栽培和水培栽培等新型农业作物生产企业的种植业务。
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3.发明申请METHOD FOR FERMENTATION AND CULTIVATION, FERMENTED PLANT EXTRACT, FERMENTED PLANT EXTRACT POWDER, AND COMPOSITION CONTAINING THE EXTRACT OF FERMENTED PLANT 审中-公开发酵和培养方法，发酵植物提取物，发酵植物提取粉和含有植物提取物的组合物公开(公告)号：US20120058134A1
公开(公告)日：2012-03-08
申请号：US13296551
申请日：2011-11-15
CPC分类号： C12N1/20 , A23L7/104 , A23L11/09 , A23L33/105 , A23V2002/00 , A61K36/03 , A61K36/48 , A61K36/88 , A61K36/899 , C12P1/04 , C12P19/04 , Y02P60/877 , A23V2200/324 , A23V2250/21
摘要： For the purpose of providing a method of safely and inexpensively producing a fermented plant extract containing an immunopotentiator at a high concentration, the method for fermentation and culture of the present invention ferments a plant component such as wheat flour using Pantoea agglomerans which is a gram negative bacterium which lives in a symbiotic relationship with a plant such as wheat and apple. It becomes possible to remarkably augment an immunopotentiation action which the plant has. In addition, these are not contaminated with impurities derived from animal components, and thus these are highly safe.
摘要翻译： 为了提供一种安全廉价地生产含有高浓度免疫增强剂的发酵植物提取物的方法，本发明的发酵和培养方法使用成团革兰氏酵母（Pantoea） 与小麦和苹果等植物共生关系的细菌。 可以显着增加植物具有的免疫增强作用。 此外，这些不会被来自动物成分的杂质污染，因此这些是高度安全的。
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4.发明申请公开(公告)号：US20100016577A1
公开(公告)日：2010-01-21
申请号：US12308997
申请日：2007-02-28
IPC分类号： C08B37/00
CPC分类号： A61K8/60 , A23K20/158 , A23L33/115 , A61Q19/00
摘要： It has been found that a limulus-positive glycolipid is present in xanthan gum derived from Xanthomonas, which has been commercially available and eaten for many years, and this was purified, and it has been found that this limulus-positive glycolipid has an immunopotentiation effect. A method for safely and inexpensively producing the limulus-positive glycolipid containing an immunopotentiator at high concentrations is provided. The method for producing the limulus-positive glycolipid of the present invention comprises extracting the limulus-positive glycolipid from xanthan gum. A limulus-positive glycolipid composition containing the limulus-positive glycolipid can be used for various applications such as pharmaceuticals, pharmaceuticals for animals, quasi drugs, cosmetics, foods, functional foods, feedstuff and bath agents.
摘要翻译： 已经发现，鲎阳性糖脂存在于源自黄单胞菌属的黄原胶中，黄原胶已经可商购并食用多年，并且这被纯化，并且已经发现这种鲎阳性糖脂具有免疫增强效应 。 提供了一种安全廉价地生产含有高浓度免疫增强剂的鲎阳性糖脂的方法。 本发明的鲎阳性糖脂的制造方法包括从黄原胶中提取鲎阳性糖脂。 含有鲎阳性糖脂的鲎阳性糖脂组合物可用于各种用途，例如药物，动物药物，准药物，化妆品，食品，功能性食品，饲料和浴剂。
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公开(公告)号：US07219758B2
公开(公告)日：2007-05-22
申请号：US10726255
申请日：2003-12-02
申请人： Michael Guidry , Masatoshi Takeshita , Takashi Fujii , Yasuyuki Muramatsu , Hiroyuki Inagawa , Shuhei Adachi
发明人： Michael Guidry , Masatoshi Takeshita , Takashi Fujii , Yasuyuki Muramatsu , Hiroyuki Inagawa , Shuhei Adachi
IPC分类号： B60K1/04
CPC分类号： B60K1/00 , B60K1/04 , B60K15/067 , B60K2015/0638 , B60L11/1881 , B60Y2200/86 , B62D23/005 , B62D33/02 , Y02T90/34
摘要： An electric motor-driven vehicle comprises a seat disposed centrally on a vehicle body, a loading platform located over a loading platform receiving frame and behind the seat, and a plurality of main frame rails connected to the loading platform receiving frame. The vehicle further comprises a fuel supply piping system, at least one battery, a fuel cell and at least one fuel tank, all disposed so as to efficiently use the space within the vehicle body, and all protected from external forces by the loading platform receiving frame. A plurality of partition walls separate the at least one battery and the fuel cell from the at least one fuel tank and provide additional protection against external forces to the fuel cell and the at least one fuel tank.
摘要翻译： 电动车辆包括位于车身中心的座位，位于装载平台接收框架上方和座椅后方的装载平台，以及连接到装载平台接收框架的多个主框架轨道。 车辆还包括燃料供应管道系统，至少一个电池，燃料电池和至少一个燃料箱，其全部设置成有效地使用车体内的空间，并且通过装载平台接收器都受到外力的保护 帧。 多个分隔壁将至少一个电池和燃料电池与至少一个燃料箱分开，并提供抵抗燃料电池和至少一个燃料箱的外力的附加保护。
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公开(公告)号：US20140194287A1
公开(公告)日：2014-07-10
申请号：US14126154
申请日：2012-06-14
申请人： Gen-Ichiro Soma , Hiroyuki Inagawa , Chie Kohchi
发明人： Gen-Ichiro Soma , Hiroyuki Inagawa , Chie Kohchi
CPC分类号： C12N1/066 , A01N63/02 , A23K10/16 , A23K20/00 , A23K20/10 , A23K40/10 , A23K50/40 , A23L33/10 , A23L33/135 , A23V2002/00 , A61K8/99 , A61K35/74 , A61K39/39 , A61K2800/10 , A61K2800/70 , A61Q19/00 , C05F11/00 , C07K14/472 , C12N1/20
摘要： A crushed bacterial body can be obtained by culturing a gram-negative bacterium and physically crushing a body of the gram-negative bacterium, comprises all components including immunostimulatory components in the bacterial body, and comprises LPSs having molecular weights of 20,000 or less as active ingredients. The crushed bacterial body is effective as a health food, drug, skin-care product, bath agent, feedstuff for protecting crustaceans, shellfish, fish, poultry, farm animals and pet animals from infections, and a feed additive for growth promotion, and can provide an innate immunostimulatory substance derived from a gram-negative bacterial body having infection-preventing effects and growth promoting effects, an inexpensive and practical microbial crushed bacterial body, and a composition thereof.
摘要翻译： 通过培养革兰氏阴性细菌并物理地破碎革兰氏阴性细菌的体内，可以获得破碎的细菌体，其包括细菌体中包含免疫刺激成分的所有成分，并且包含分子量为20,000以下的LPS作为活性成分 。 破碎的细菌体作为保健食品，药物，护肤品，浴剂，用于保护甲壳类动物，贝类，鱼类，禽类，农场动物和感染宠物的饲料以及促进生长的饲料添加剂是有效的，并且可以 提供具有感染预防作用和生长促进作用的革兰氏阴性菌体的廉价免疫刺激物质，廉价实用的微生物破碎细菌体及其组合物。
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7.发明授权Method for fermentation and cultivation, fermented plant extract, fermented plant extract powder, and composition containing the extract of fermented plant 有权发酵和培养方法，发酵植物提取物，发酵植物提取物粉末和含有发酵植物提取物的组合物公开(公告)号：US08075928B2
公开(公告)日：2011-12-13
申请号：US10572853
申请日：2004-09-22
CPC分类号： C12N1/20 , A23L7/104 , A23L11/09 , A23L33/105 , A23V2002/00 , A61K36/03 , A61K36/48 , A61K36/88 , A61K36/899 , C12P1/04 , C12P19/04 , Y02P60/877 , A23V2200/324 , A23V2250/21
摘要： For the purpose of providing a method of safely and inexpensively producing a fermented plant extract containing an immunopotentiator at a high concentration, the method for fermentation and culture of the present invention ferments a plant component such as wheat flour using Pantoea agglomerans which is a gram negative bacterium which lives in a symbiotic relationship with a plant such as wheat and apple. It becomes possible to remarkably augment an immunopotentiation action which the plant has. In addition, these are not contaminated with impurities derived from animal components, and thus these are highly safe.
摘要翻译： 为了提供一种安全廉价地生产含有高浓度免疫增强剂的发酵植物提取物的方法，本发明的发酵和培养方法使用成团革兰氏酵母（Pantoea） 与小麦和苹果等植物共生关系的细菌。 可以显着增加植物具有的免疫增强作用。 此外，这些不会被来自动物成分的杂质污染，因此这些是高度安全的。
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公开(公告)号：US5251718A
公开(公告)日：1993-10-12
申请号：US820324
申请日：1992-01-13
申请人： Hiroyuki Inagawa , Takashi Yamamura
发明人： Hiroyuki Inagawa , Takashi Yamamura
摘要： A snowmobile having an improved cooling arrangement including a front mounted radiator and a ducting system for ducting cooling air through the radiator and away from the windshield and rider's hands on the handlebars of the snowmobile.
摘要翻译： 具有改进的冷却布置的雪地车，包括前安装的散热器和用于通过散热器管道冷却空气并远离挡风玻璃和驾驶员的手在雪地车手柄上的管道系统。
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9.发明申请公开(公告)号：US20120046459A1
公开(公告)日：2012-02-23
申请号：US13287228
申请日：2011-11-02
IPC分类号： C08B37/00
CPC分类号： A61K8/60 , A23K20/158 , A23L33/115 , A61Q19/00
摘要： It has been found that a limulus-positive glycolipid is present in xanthan gum derived from Xanthomonas, which has been commercially available and eaten for many years, and this was purified, and it has been found that this limulus-positive glycolipid has an immunopotentiation effect. A method for safely and inexpensively producing the limulus-positive glycolipid containing an immunopotentiator at high concentrations is provided. The method for producing the limulus-positive glycolipid of the present invention comprises extracting the limulus-positive glycolipid from xanthan gum. A limulus-positive glycolipid composition containing the limulus-positive glycolipid can be used for various applications such as pharmaceuticals, pharmaceuticals for animals, quasi drugs, cosmetics, foods, functional foods, feedstuff and bath agents.
摘要翻译： 已经发现，鲎阳性糖脂存在于源自黄单胞菌属的黄原胶中，黄原胶已经可商购并食用多年，并且这被纯化，并且已经发现这种鲎阳性糖脂具有免疫增强效应 。 提供了一种安全廉价地生产含有高浓度免疫增强剂的鲎阳性糖脂的方法。 本发明的鲎阳性糖脂的制造方法包括从黄原胶中提取鲎阳性糖脂。 含有鲎阳性糖脂的鲎阳性糖脂组合物可用于各种用途，例如药物，动物药物，准药物，化妆品，食品，功能性食品，饲料和浴剂。
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10.发明授权公开(公告)号：US07485698B2
公开(公告)日：2009-02-03
申请号：US11413751
申请日：2006-04-28
CPC分类号： C07K14/525 , A61K38/00
摘要： An object of the present invention is to provide a novel malignant glioma antitumor agent and malignant glioma antitumor agent for animals, and in order to achieve this object, in the present invention a polypeptide indicated by the following (a) or (b), or a mixture thereof, is contained in a malignant glioma antitumor agent: (a) a polypeptide comprising the amino acid sequence represented by SEQ. ID NO. 1 or SEQ. ID NO. 2; or (b) a polypeptide comprising the amino acid sequence represented by SEQ. ID NO. 1 or SEQ. ID NO. 2 with 1 or more amino acids deleted, substituted or added, and which has malignant glioma antitumor action.
摘要翻译： 本发明的目的是提供一种用于动物的新型恶性神经胶质瘤抗肿瘤剂和恶性胶质瘤抗肿瘤剂，为了实现该目的，在本发明中，由以下（a）或（b）表示的多肽或 其混合物包含在恶性胶质瘤抗肿瘤剂中：（a）包含SEQ ID NO：1所示的氨基酸序列的多肽。 证件号码。 1或SEQ。 证件号码。 2; 或（b）包含SEQ ID NO：1所示的氨基酸序列的多肽。 证件号码。 1或SEQ。 证件号码。 2具有1个或多个氨基酸缺失，取代或添加，并具有恶性胶质瘤抗肿瘤作用。
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