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公开(公告)号：US20100331864A1
公开(公告)日：2010-12-30
申请号：US12494887
申请日：2009-06-30
IPC分类号： A61B17/08
CPC分类号： A61F2/0063 , A61F2/042 , A61F2002/0068 , A61L27/18 , A61L27/48 , A61L27/58 , A61L2430/22 , C08L67/04
摘要： A tissue engineering construct made from a nonwoven fabric. The fabric is made from first and second staple fibers. The first staple fibers are made from a first biocompatible, bioabsorbable material, and the second staple fibers are made from a second biocompatible, bioabsorbable material. The first material has a melting temperature lower than the second material. The fabric is formed into a three-dimensional construct suitable for the repair of urinary tract structures.
摘要翻译： 由非织造织物制成的组织工程结构。 织物由第一和第二短纤维制成。 第一短纤维由第一生物相容的生物可吸收材料制成，第二短纤维由第二生物相容的生物可吸收材料制成。 第一种材料的熔融温度低于第二种材料。 该织物形成适于修复尿道结构的三维结构。
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公开(公告)号：US08546338B2
公开(公告)日：2013-10-01
申请号：US12962775
申请日：2010-12-08
申请人： Jackie J. Donners , Aruna Nathan
发明人： Jackie J. Donners , Aruna Nathan
摘要： We have disclosed dicephalic amphiphiles having peptide sequences as the head groups. We have also disclosed self-assembly hydrogels prepared from the dicephalic peptide amphiphiles. These hydrogels are useful for the encapsulation and delivery of bioactives to a patient.
摘要翻译： 我们已经公开了具有肽序列作为头基的二头头两亲物。 我们还公开了从二头头肽两亲物制备的自组装水凝胶。 这些水凝胶可用于将生物活性物质包封并递送给患者。
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3.发明申请SELF-ASSEMBLING HYDROGELS BASED ON DICEPHALIC PEPTIDE AMPHIPHILES 有权基于DICEPHALIC PEPTIDE AMPHIPHILHES的自组装水凝胶公开(公告)号：US20120148674A1
公开(公告)日：2012-06-14
申请号：US12962775
申请日：2010-12-08
申请人： Jackie J. Donners , Aruna Nathan
发明人： Jackie J. Donners , Aruna Nathan
IPC分类号： A61K9/14 , C07K7/06 , C07K7/08 , A61K38/02 , A61K35/12 , A61K31/7105 , A61K39/395 , A61K38/18 , A61K31/713 , A61K35/44 , A61K35/23 , C07K4/00 , A61K31/7088
摘要： We have disclosed dicephalic amphiphiles having peptide sequences as the head groups. We have also disclosed self-assembly hydrogels prepared from the dicephalic peptide amphiphiles. These hydrogels are useful for the encapsulation and delivery of bioactives to a patient.
摘要翻译： 我们已经公开了具有肽序列作为头基的二头头两亲物。 我们还公开了从二头头肽两亲物制备的自组装水凝胶。 这些水凝胶可用于将生物活性物质包封并递送给患者。
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公开(公告)号：US08758447B2
公开(公告)日：2014-06-24
申请号：US12494887
申请日：2009-06-30
CPC分类号： A61F2/0063 , A61F2/042 , A61F2002/0068 , A61L27/18 , A61L27/48 , A61L27/58 , A61L2430/22 , C08L67/04
摘要： A tissue engineering construct made from a nonwoven fabric. The fabric is made from first and second staple fibers. The first staple fibers are made from a first biocompatible, bioabsorbable material, and the second staple fibers are made from a second biocompatible, bioabsorbable material. The first material has a melting temperature lower than the second material. The fabric is formed into a three-dimensional construct suitable for the repair of urinary tract structures.
摘要翻译： 由非织造织物制成的组织工程结构。 织物由第一和第二短纤维制成。 第一短纤维由第一生物相容的生物可吸收材料制成，第二短纤维由第二生物相容的生物可吸收材料制成。 第一种材料的熔融温度低于第二种材料。 该织物形成适于修复尿道结构的三维结构。
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公开(公告)号：US20100151575A1
公开(公告)日：2010-06-17
申请号：US12335186
申请日：2008-12-15
IPC分类号： C12N5/02
CPC分类号： C12N5/0686 , C12N2533/40
摘要： Methods of making conditioned media by culturing cells on nonwoven substrates are disclosed. More specifically, methods of making conditioned media by culturing mammalian kidney-derived cells on nonwoven substrates are disclosed.
摘要翻译： 公开了通过在非织造基底上培养细胞来制备条件培养基的方法。 更具体地，公开了通过在非织造基底上培养哺乳动物肾源细胞来制备条件培养基的方法。
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公开(公告)号：US20100152530A1
公开(公告)日：2010-06-17
申请号：US12335169
申请日：2008-12-15
申请人： Mark Timmer , Chunlin Yang , Clifford G. Volpe , Joseph J. Hammer , Dhanuraj Shetty , Daniel J. Keeley , Jackie J. Donners
发明人： Mark Timmer , Chunlin Yang , Clifford G. Volpe , Joseph J. Hammer , Dhanuraj Shetty , Daniel J. Keeley , Jackie J. Donners
IPC分类号： A61F2/00
CPC分类号： A61F2/0045 , A61F2/0063 , A61F2210/0004 , A61F2250/0067 , B32B5/022 , B32B5/026 , B32B5/08 , B32B5/26 , B32B7/12 , B32B2250/20 , B32B2262/0253 , B32B2262/0261 , B32B2262/0276 , B32B2262/06 , B32B2262/14 , B32B2307/72 , B32B2535/00 , D04H1/492 , D04H3/11
摘要： Tissue engineering devices for pelvic floor repair are disclosed. More specifically, tissue engineering devices made of an implant, having a central portion at least partially embedded within a nonwoven felt are disclosed.
摘要翻译： 公开了用于盆底修复的组织工程装置。 更具体地，公开了由植入物制成的组织工程装置，其具有至少部分地嵌入非织造织物毡内的中心部分。
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