公开(公告)号：US20150190229A1

公开(公告)日：2015-07-09

申请号：US14660791

申请日：2015-03-17

Applicant: Jacques Seguin

Inventor： Jacques Seguin

IPC: A61F2/24

CPC classification number: A61F2/2427 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/2454 ,  A61F2/246

Abstract: Methods and apparatus are provided for repairing or replacing a defective cardiac valve including a prosthetic leaflet assembly having an expandable frame with one or more anchors configured to engage a predetermined region of the defective cardiac valve in an expanded deployed state, and at least one prosthetic leaflet coupled to the expandable frame. The prosthetic leaflet assembly is configured such that the prosthetic leaflet is suspended within a flow path of the defective cardiac valve and coapts with, and improves functioning of, one or more native leaflets of the defective cardiac valve.

Abstract translation: 提供了用于修复或更换有缺陷的心脏瓣膜的方法和装置，所述有缺陷的心脏瓣膜包括具有可扩张框架的假体小叶组件，所述假体小叶组件具有一个或多个锚构件，其构造成以处于展开的展开状态接合故障心脏瓣膜的预定区域，以及至少一个假体小叶 耦合到可扩展框架。 假体小叶组件被构造成使得假体小叶被悬挂在有缺陷的心脏瓣膜的流动路径中并与有缺陷的心脏瓣膜的一个或多个天然小叶具有并且改善功能。

公开(公告)号：US08801779B2

公开(公告)日：2014-08-12

申请号：US13104828

申请日：2011-05-10

Applicant: Jacques Seguin ,  Georg Börtlein

Inventor： Jacques Seguin ,  Georg Börtlein

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61B17/0218 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2210/0023 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0003 ,  A61F2250/0039 ,  A61F2250/0048 ,  A61F2250/0069 ,  Y10S623/904

Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.

Abstract translation: 一种用于替换缺陷天然瓣膜的人工瓣膜组件包括支撑在可扩张瓣膜支架上的置换瓣膜。 如果需要，可以使用一个或多个锚。 完全支撑瓣膜环，瓣膜小叶和瓣膜关节点的瓣膜支撑件被构造为可折叠的，用于经腔输送，并且当组件被适当定位时，其可扩张以接触天然瓣膜的解剖环。 当膨胀时，锚固件接合管腔壁，并且当定位就位时防止阀组件的大量迁移。 假体瓣膜组件围绕导管可压缩，并且被外护套限制为扩张。 导管可以插入体内的腔内，例如股动脉，并且被输送到期望的位置，例如心脏。 当外鞘缩回时，假体瓣膜组件膨胀到扩张位置，使得瓣膜和瓣膜支撑件在缺陷的天然瓣膜内膨胀，并且锚固件与腔壁接合。

公开(公告)号：US20120016464A1

公开(公告)日：2012-01-19

申请号：US12839363

申请日：2010-07-19

Applicant: Jacques Seguin

Inventor： Jacques Seguin

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2427 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/2442 ,  A61F2210/0014 ,  A61F2220/0016 ,  A61F2220/0033 ,  A61F2230/0006 ,  A61F2230/001 ,  A61F2230/0013 ,  A61F2230/0091 ,  A61F2250/0039 ,  A61F2250/006 ,  A61F2250/0069 ,  A61F2250/0098

Abstract: Methods and apparatus are provided for repairing or replacing a defective cardiac valve including an anchor having a double helix configured to engage the cardiac valve leaflets of a diseased or defective cardiac valve, and a replacement valve body disposed in an expandable stent configured to be disposed within the anchor so that the anchor limits expansion of the expandable stent. The expandable stent of the replacement valve body may be self-expanding or mechanically expanded, e.g., using a balloon catheter or catheter-based mandrel and the valve body may be formed of animal tissue or a synthetic fabric.

Abstract translation: 提供了用于修复或更换有缺陷的心脏瓣膜的方法和装置，所述有缺陷的心脏瓣膜包括具有构造成接合患病或有缺陷的心脏瓣膜的心脏瓣膜的双螺旋的锚固件，以及设置在可扩张支架中的替换阀体， 锚固件使得锚固件限制了可扩张支架的膨胀。 替换阀体的可扩张支架可以是自膨胀的或机械膨胀的，例如使用气囊导管或基于导管的心轴，并且阀体可以由动物组织或合成织物形成。

公开(公告)号：US20110301692A1

公开(公告)日：2011-12-08

申请号：US13212227

申请日：2011-08-18

Applicant: Jacques SEGUIN

Inventor： Jacques SEGUIN

IPC: A61F2/82 ,  A61F2/24

CPC classification number: A61F2/2403 ,  A61F2/2418 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2230/0067 ,  A61F2250/006

Abstract: A prosthetic valve assembly can include a radially expandable stent. The stent can includea first expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen, a second expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen. The stent can also include a plurality of rods extending between the first annular portion and the second annular portion. The prosthetic valve assembly can further include an implantable prosthetic valve mounted to the stent such that the valve is between the first annular portion and the second annular portion. The prosthetic valve assembly is configured to be delivered by catheterization.

Abstract translation: 假体瓣膜组件可包括径向可扩张的支架。 支架可以包括第一可膨胀环形部分，其被构造成处于膨胀状态的第一可膨胀环形部分，以承受本体体腔的壁;第二可膨胀环形部分，其被构造成处于膨胀状态，以抵靠本机的壁 体腔。 支架还可以包括在第一环形部分和第二环形部分之间延伸的多个杆。 假体瓣膜组件还可包括安装到支架上的可植入假体瓣，使得瓣膜位于第一环形部分和第二环形部分之间。 假体瓣膜组件被构造成通过导管插入进行输送。

公开(公告)号：US08002826B2

公开(公告)日：2011-08-23

申请号：US12578818

申请日：2009-10-14

Applicant: Jacques Seguin

Inventor： Jacques Seguin

IPC: A61F2/24

CPC classification number: A61F2/2403 ,  A61F2/2418 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2230/0067 ,  A61F2250/006

Abstract: The present invention is an assembly comprising a prosthetic valve to be implanted; a radially expandable stent comprising at least one zone intended to be expanded to allow the stent, in the expanded state, to bear against the wall of the body duct to be fitted with the valve, this bearing making it possible to immobilize this stent with respect to this wall; and means for mounting the valve with respect to the stent, making it possible to connect the valve to the stent in such a way that the placement of the stent allows the valve to be mounted in the body duct, and expansion means such as a balloon catheter being provided to trigger expansion of the stent at the implantation site. According to the invention, the valve and the stent are designed in such a way that, at the moment when the stent is expanded, the valve is situated outside the zone or zones of the stent that are subjected to said expansion means. The invention thus consists in separating the valve and said zone or zones to be expanded, so that the expansion of the stent can be effected with an expansion force suitable for perfect anchoring of this stent in the wall of the body duct to be fitted with the valve, and without any risk of destruction or damage of the valve.

Abstract translation: 本发明是一种包括待植入的假体瓣膜的组件; 包括至少一个区域的径向可扩张的支架，所述至少一个区域旨在被扩张以允许处于膨胀状态的支架抵靠所述主体管道的壁以与所述瓣膜配合，所述轴承使得可以将该支架固定在 到这墙上 以及用于相对于支架安装阀的装置，使得可以将阀连接到支架，使得支架的放置允许阀安装在体导管中，并且膨胀装置例如气囊 提供导管以在植入部位触发支架的扩张。 根据本发明，阀和支架被设计成使得当支架膨胀时，阀位于经受所述膨胀装置的支架的区域之外。 因此，本发明在于将瓣膜和所述要扩张的区域或区域分开，使得支架的膨胀可以用适合于将该支架完美锚固在体导管的壁中的膨胀力来实现，以配合 阀门，并且没有任何破坏或损坏阀门的风险。

公开(公告)号：US20100030328A1

公开(公告)日：2010-02-04

申请号：US12481350

申请日：2009-06-09

Applicant: Jacques Seguin ,  Bruno Lecointe ,  Remi Gerriet

Inventor： Jacques Seguin ,  Bruno Lecointe ,  Remi Gerriet

IPC: A61F2/24

CPC classification number: A61F2/2466 ,  A61B17/064 ,  A61B2017/00243 ,  A61B2017/0649 ,  A61B2017/081 ,  A61F2/2445

Abstract: An apparatus for treating a heart valve apparatus includes at least two anchoring elements designed to be anchored at the annulus and/or heart wall of the valve to be treated. Each anchoring element has a support surface. At least one linking element includes a central branch and two curved side branches, one of which is designed to be engaged on the support surface of an anchoring element, while the other is designed to be engaged on the support surface of another anchoring element, the linking element then being designed to be pivoted to a position such that the anchoring elements interconnect and in which the ends of the central branch are located in the vicinity of the support surfaces.

Abstract translation: 用于治疗心脏瓣膜装置的装置包括设计成锚定在待治疗的瓣膜的环空和/或心壁上的至少两个锚定元件。 每个锚固元件具有支撑表面。 至少一个连接元件包括中央分支和两个弯曲的侧分支，其中一个被设计成接合在锚固元件的支撑表面上，而另一个连接元件被设计成接合在另一个锚定元件的支撑表面上， 连接元件然后被设计成枢转到一个位置，使得锚固元件互连，并且其中中心支路的端部位于支撑表面附近。

公开(公告)号：US07344556B2

公开(公告)日：2008-03-18

申请号：US10435096

申请日：2003-05-09

Applicant: Jacques Seguin ,  Robert John Elicker ,  Jean-Claude Laborde

Inventor： Jacques Seguin ,  Robert John Elicker ,  Jean-Claude Laborde

IPC: A61F2/06

CPC classification number: A61F2/91 ,  A61F2/856 ,  A61F2/915 ,  A61F2/954 ,  A61F2/958 ,  A61F2/966 ,  A61F2002/061 ,  A61F2002/067 ,  A61F2002/826 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2002/9505 ,  A61F2002/9517 ,  A61F2002/9583 ,  A61F2002/9665 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2250/0039

Abstract: A device and method for treating pathological narrowing of fluid-carrying conduits of the human body (such as blood vessels) in an area of a bifurcation is disclosed. In particular, a stent delivery system configured to carry one or more of a pair of dissimilar stents. At least one of the stents is particularly suited for treating a widened portion of a blood vessel immediately proximal to a bifurcation. The stent delivery system can also include a handpiece adapted to selectively deliver the stents.

Abstract translation: 公开了一种用于治疗分叉区域中的人体（例如血管）的流体输送管道的病理变窄的装置和方法。 具体地，支架输送系统被配置为承载一对不同支架中的一个或多个。 支架中的至少一个特别适于治疗紧邻分叉处的血管的加宽部分。 支架输送系统还可以包括适于选择性地输送支架的手持件。

公开(公告)号：US07329278B2

公开(公告)日：2008-02-12

申请号：US11352614

申请日：2006-02-13

Applicant: Jacques Seguin ,  Georg Börtlein

Inventor： Jacques Seguin ,  Georg Börtlein

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61B17/0218 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2210/0023 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0003 ,  A61F2250/0039 ,  A61F2250/0048 ,  A61F2250/0069 ,  Y10S623/904

Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.

Abstract translation: 一种用于替换缺陷天然瓣膜的人工瓣膜组件包括支撑在可扩张瓣膜支架上的置换瓣膜。 如果需要，可以使用一个或多个锚固件。 完全支撑瓣膜环，瓣膜小叶和瓣膜关节点的瓣膜支撑件被构造为可折叠的，用于经腔输送，并且当组件被适当定位时，其可扩张以接触天然瓣膜的解剖环。 当膨胀时，锚固件接合管腔壁，并且当定位就位时防止阀组件的大量迁移。 假体瓣膜组件围绕导管可压缩，并且被外护套限制为扩张。 导管可以插入体内的腔内，例如股动脉，并且被输送到期望的位置，例如心脏。 当外鞘缩回时，假体瓣膜组件膨胀到扩张位置，使得瓣膜和瓣膜支撑件在缺陷的天然瓣膜内膨胀，并且锚固件与腔壁接合。

公开(公告)号：US20060100685A1

公开(公告)日：2006-05-11

申请号：US11124905

申请日：2005-05-09

Applicant: Jacques Seguin ,  Jean-Claude Laborde

Inventor： Jacques Seguin ,  Jean-Claude Laborde

IPC: A61F2/06

CPC classification number: A61F2/91 ,  A61F2/90 ,  A61F2/915 ,  A61F2/95 ,  A61F2/954 ,  A61F2002/067 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2230/0067 ,  A61F2250/0039 ,  A61F2250/0098

Abstract: An apparatus for treating an area of bifurcation where a principal body conduit separates into at least two secondary conduits comprises a radially expandable first stent body. The first stent body has a substantially conical shape and a first end having a greater diameter than a second end when fully expanded. The first stent body is preferably shaped to be independent of any other stent bodies, and is free of any means for connecting to any other stent bodies when fully expanded.

Abstract translation: 一种用于处理分叉区域的装置，其中主体导管分离成至少两个次级导管包括可径向扩张的第一支架体。 第一支架主体具有基本上圆锥形的形状，并且当完全膨胀时具有比第二端更大的直径的第一端。 优选地，第一支架主体被成形为独立于任何其它支架体，并且在完全扩张时没有任何用于连接到任何其它支架体的装置。

公开(公告)号：US6068655A

公开(公告)日：2000-05-30

申请号：US11214

申请日：1998-04-03

Applicant: Jacques Seguin ,  Jean-Claude Laborde

Inventor： Jacques Seguin ,  Jean-Claude Laborde

IPC: A61B19/00 ,  A61F2/00 ,  A61F2/06 ,  A61F2/07 ,  A61F2/856 ,  A61F2/90 ,  A61F2/91 ,  A61F2/915

CPC classification number: A61F2/91 ,  A61F2/07 ,  A61F2/915 ,  A61B90/39 ,  A61F2/856 ,  A61F2/90 ,  A61F2002/065 ,  A61F2002/075 ,  A61F2002/91525 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2210/0019 ,  A61F2220/0058 ,  A61F2230/0013 ,  A61F2250/0006

Abstract: This invention features a device (1) comprising: at least one radially expansible segment (7, 8) with, in the expanded state, a transversal cross section substantially greater than the transversal cross section of one of the secondary ducts (3); one segment (6) with, in the expanded state, a truncated shape, corresponding to the shape of the bifurcation at the flared transition zone (11) which separates the main duct (2) from the secondary ducts (3), and a flexible link (9) between these two segments (6, 7), enabling their adjustment relative to each other, according to the orientation of the secondary duct (3) receiving the radially expandable segment (7) relative to the flared transition zone (11).

Abstract translation: PCT No.PCT / FR97 / 00999 Sec。 371日期：1998年4月3日 102（e）日期1998年4月3日PCT提交1997年6月5日PCT公布。 公开号WO97 / 46174 1997年12月11日的日期本发明的特征在于一种装置（1），包括：至少一个径向可膨胀段（7,8），其处于膨胀状态，横截面基本上大于其中一个副管道的横截面 （3）; 具有膨胀状态的一个截面形状（6）对应于将主管道（2）与次管道（3）分隔开的扩张过渡区域（11）处的分叉形状，并且具有柔性 根据相对于扩张过渡区域（11）接收径向可扩张段（7）的次级管道（3）的方向，使得它们能够相对于彼此调节， 。