公开(公告)号：US20110125257A1

公开(公告)日：2011-05-26

申请号：US13010010

申请日：2011-01-20

Applicant: Jacques SEGUIN ,  Georg Börtlein

Inventor： Jacques SEGUIN ,  Georg Börtlein

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61B17/0218 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2210/0023 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0003 ,  A61F2250/0039 ,  A61F2250/0048 ,  A61F2250/0069 ,  Y10S623/904

Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.

Abstract translation: 一种用于替换缺陷天然瓣膜的人工瓣膜组件包括支撑在可扩张瓣膜支架上的置换瓣膜。 如果需要，可以使用一个或多个锚。 完全支撑瓣膜环，瓣膜小叶和瓣膜关节点的瓣膜支撑件被构造为可折叠的，用于经腔输送，并且当组件被适当定位时，其可扩张以接触天然瓣膜的解剖环。 当膨胀时，锚固件接合管腔壁，并且当定位就位时防止阀组件的大量迁移。 假体瓣膜组件围绕导管可压缩，并且被外护套限制为扩张。 导管可以插入体内的腔内，例如股动脉，并且被输送到期望的位置，例如心脏。 当外鞘缩回时，假体瓣膜组件膨胀到扩张位置，使得瓣膜和瓣膜支撑件在缺陷的天然瓣膜内膨胀，并且锚固件与腔壁接合。

公开(公告)号：US20110301692A1

公开(公告)日：2011-12-08

申请号：US13212227

申请日：2011-08-18

Applicant: Jacques SEGUIN

Inventor： Jacques SEGUIN

IPC: A61F2/82 ,  A61F2/24

CPC classification number: A61F2/2403 ,  A61F2/2418 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2230/0067 ,  A61F2250/006

Abstract: A prosthetic valve assembly can include a radially expandable stent. The stent can includea first expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen, a second expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen. The stent can also include a plurality of rods extending between the first annular portion and the second annular portion. The prosthetic valve assembly can further include an implantable prosthetic valve mounted to the stent such that the valve is between the first annular portion and the second annular portion. The prosthetic valve assembly is configured to be delivered by catheterization.

Abstract translation: 假体瓣膜组件可包括径向可扩张的支架。 支架可以包括第一可膨胀环形部分，其被构造成处于膨胀状态的第一可膨胀环形部分，以承受本体体腔的壁;第二可膨胀环形部分，其被构造成处于膨胀状态，以抵靠本机的壁 体腔。 支架还可以包括在第一环形部分和第二环形部分之间延伸的多个杆。 假体瓣膜组件还可包括安装到支架上的可植入假体瓣，使得瓣膜位于第一环形部分和第二环形部分之间。 假体瓣膜组件被构造成通过导管插入进行输送。

公开(公告)号：US20110238165A1

公开(公告)日：2011-09-29

申请号：US13156760

申请日：2011-06-09

Applicant: Jacques SEGUIN

Inventor： Jacques SEGUIN

IPC: A61F2/24

CPC classification number: A61B17/1285 ,  A61B17/00234 ,  A61B17/0218 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/10 ,  A61B17/122 ,  A61B17/30 ,  A61B90/03 ,  A61B2017/00243 ,  A61B2017/00353 ,  A61B2017/00783 ,  A61B2017/081 ,  A61B2017/1103 ,  A61B2017/306 ,  A61B2090/037

Abstract: The invention comprises a surgical instrument including an external tube (2) and two elongated members (4) positioned in said tube (2), each of which includes a distal end (10a) for capturing one of the two tissue zones (M1, M2) to be attached. The instrument (1) may further comprise a catching member (22, 25) for each tissue (M1, M2) to be attached; a rod (15, 16) linked to each catching member (22, 25) enabling tension to move axially, said rod (15, 16) being separable from said catching member (22, 25) when a tension is exerted on it beyond a certain threshold; and a member (17a) forming a stop for locking axially each catching member (22, 25) during said tension.

Abstract translation: 本发明包括外科器械，其包括外管（2）和位于所述管（2）中的两个细长构件（4），每个细长构件（4）包括用于捕获两个组织区（M1，M2 ）附加。 仪器（1）还可以包括用于要附接的每个组织（M1，M2）的捕获构件（22,25） 连接到每个捕获构件（22,25）的杆（15,16），使得张力能够轴向地移动，当其上施加张力超过一个或更多的张力时，所述杆（15,16）可与所述捕获构件（22,25）分离 一定的门槛; 以及形成用于在所述张力期间轴向地锁定每个捕获构件（22,25）的止挡件的构件（17a）。

公开(公告)号：US20100036485A1

公开(公告)日：2010-02-11

申请号：US12578818

申请日：2009-10-14

Applicant: Jacques SEGUIN

Inventor： Jacques SEGUIN

IPC: A61F2/24

CPC classification number: A61F2/2403 ,  A61F2/2418 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2230/0067 ,  A61F2250/006

Abstract: The present invention is an assembly comprising a prosthetic valve to be implanted; a radially expandable stent comprising at least one zone intended to be expanded to allow the stent, in the expanded state, to bear against the wall of the body duct to be fitted with the valve, this bearing making it possible to immobilize this stent with respect to this wall; and means for mounting the valve with respect to the stent, making it possible to connect the valve to the stent in such a way that the placement of the stent allows the valve to be mounted in the body duct, and expansion means such as a balloon catheter being provided to trigger expansion of the stent at the implantation site. According to the invention, the valve and the stent are designed in such a way that, at the moment when the stent is expanded, the valve is situated outside the zone or zones of the stent that are subjected to said expansion means. The invention thus consists in separating the valve and said zone or zones to be expanded, so that the expansion of the stent can be effected with an expansion force suitable for perfect anchoring of this stent in the wall of the body duct to be fitted with the valve, and without any risk of destruction or damage of the valve.

Abstract translation: 本发明是一种包括待植入的假体瓣膜的组件; 包括至少一个区域的径向可扩张的支架，所述至少一个区域旨在被扩张以允许处于膨胀状态的支架抵靠所述主体管道的壁以与所述瓣膜配合，所述轴承使得可以将该支架固定在 到这墙上 以及用于相对于支架安装阀的装置，使得可以将阀连接到支架，使得支架的放置允许阀安装在体导管中，并且膨胀装置例如气囊 提供导管以在植入部位触发支架的扩张。 根据本发明，阀和支架被设计成使得当支架膨胀时，阀位于经受所述膨胀装置的支架的区域之外。 因此，本发明在于将瓣膜和所述要扩张的区域或区域分开，使得支架的膨胀可以用适合于将该支架完美锚固在体导管的壁中的膨胀力来实现，以配合 阀门，并且没有任何破坏或损坏阀门的风险。

公开(公告)号：US20230076361A1

公开(公告)日：2023-03-09

申请号：US17466956

申请日：2021-09-03

Applicant: Jacques SEGUIN

Inventor： Jacques SEGUIN

IPC: G16H50/20 ,  G16H10/60 ,  G16H40/67 ,  G06Q20/38 ,  G06F21/60 ,  A61B5/0205

Abstract: Systems and methods are provided involving various medical monitoring and/or diagnostic systems. The monitoring and diagnostic systems may involve one or more connected devices (e.g., a smart watch and/or other sensor device) and may continuously monitor an individual and analyze physiological and other data to determine a medical device, condition or event has occurred. The monitoring and diagnostic systems may be a guided self-examination system for determining a medical diagnosis, condition or event. The medical monitoring and diagnostic systems may even be specific to a family or individuals in a certain geographic location.

公开(公告)号：US20230070895A1

公开(公告)日：2023-03-09

申请号：US17656206

申请日：2022-03-23

Applicant: Jacques SEGUIN

Inventor： Jacques SEGUIN

IPC: G16H40/67 ,  A61B5/00 ,  G16H10/60 ,  G16H80/00

Abstract: Systems and methods are provided involving various medical monitoring and/or diagnostic systems. The monitoring and diagnostic systems may involve one or more connected devices (e.g., a smart watch and/or other sensor device) and may continuously monitor an individual and analyze physiological and other data to determine a medical diagnosis, condition or event has occurred. The monitoring and diagnostic systems may be a guided self-examination system for determining a medical diagnosis, condition or event. The medical monitoring and diagnostic systems may even be specific to a family or individuals in a certain geographic location. The systems may determine treatment based on a medical diagnosis or event and may cause the treatment to be delivered to a location of the user or a medical facility.

公开(公告)号：US20160354558A1

公开(公告)日：2016-12-08

申请号：US15241030

申请日：2016-08-18

Applicant: Jacques SEGUIN ,  Emad SABRY

Inventor： Jacques SEGUIN ,  Emad SABRY

IPC: A61M11/00 ,  A61K31/135 ,  A61M15/08 ,  A61K9/00 ,  A61M39/22 ,  A61M31/00 ,  A61K31/4535 ,  A61K31/485

CPC classification number: A61M11/00 ,  A61K9/0043 ,  A61K9/0078 ,  A61K31/135 ,  A61K31/4535 ,  A61K31/485 ,  A61K31/5517 ,  A61K45/06 ,  A61M15/08 ,  A61M31/00 ,  A61M39/22 ,  A61M2016/0021 ,  A61M2205/33 ,  A61M2205/3334 ,  A61M2205/3569 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2205/583 ,  A61M2205/587 ,  A61M2205/8206 ,  A61M2205/8256 ,  A61M2205/8262 ,  A61M2210/0618 ,  A61M2230/005 ,  A61M2230/20 ,  A61M2230/205 ,  A61M2230/42 ,  A61M2230/435 ,  A61K2300/00

Abstract: Devices and methods for sequential aerosolized administration of pharmaceutical agents. A portable device may be used to administer an initial dose of an active formulation comprising at least one first pharmaceutical agent and a subsequent dose of an active formulation comprising at least one second pharmaceutical agent that may have the effect of countering, enhancing, or mitigating the first pharmaceutical agent.

Abstract translation: 用于药剂的顺序雾化给药的装置和方法。 便携式装置可用于施用初始剂量的活性制剂，其包含至少一种第一药剂和随后剂量的活性制剂，其包含至少一种第二药剂，其可具有抵抗，增强或减轻 第一药剂。

公开(公告)号：US20170224477A1

公开(公告)日：2017-08-10

申请号：US15519078

申请日：2015-10-12

Applicant: Jacques SEGUIN

Inventor： Jacques SEGUIN

IPC: A61F2/24

CPC classification number: A61F2/246 ,  A61F2210/0014 ,  A61F2220/0016 ,  A61F2220/0075

Abstract: This implant (1) has a frame (2) and a membrane (3) covering this frame; —the frame (2) has: —an elongated base portion (5) formed by two curved or chevron branches being connected to connecting areas (7) of the implant (1) for connecting to the annulus of the mitral valve (100); —a longitudinal hoop (8) extending in a plane substantially perpendicular to the plane in which extends said base portion; —the membrane (3) is flexible and extends from one branch to the other while passing near the hoop (8), this membrane being connected to said branches without being stretched between these branches and this hoop so that the two thereby formed lateral portions (3a) of the membrane (3) on both sides of the implant are able to adopt either a concave shape, outwardly convex, or a recessed shape, outwardly concave.

公开(公告)号：US20160324639A1

公开(公告)日：2016-11-10

申请号：US14703775

申请日：2015-05-04

Applicant: Jacques SEGUIN

Inventor： Than NGUYEN ,  Jacques SEGUIN

IPC: A61F2/24

CPC classification number: A61F2/2454 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2427 ,  A61F2/246 ,  A61F2220/0016 ,  A61F2230/0095

Abstract: Apparatus and methods for repairing a cardiac valve, e.g., a mitral valve, are provided. The apparatus may include an expandable frame defining a curved structure in the expanded deployed state and a membrane coupled to the expandable frame. The membrane may curve around a native leaflet, e.g., the posterior leaflet, in a first plane and curve around another leaflet, e.g., the anterior leaflet, in an orthogonal plane. The membrane may be adapted to be suspended in the flow path of the cardiac valve such a first surface of the membrane abuts the native leaflet during systole and a second surface of the membrane abuts the other native leaflet during systole, thereby reducing cardiac valve regurgitation.

Abstract translation: 提供了用于修复心脏瓣膜例如二尖瓣的装置和方法。 该装置可以包括限定扩展展开状态下的弯曲结构的可扩展框架和联接到可扩展框架的膜。 膜可以在第一平面内围绕天然小叶例如后小叶弯曲，并且在正交平面中围绕另一小叶例如前小叶弯曲。 膜可以适于悬挂在心脏瓣膜的流动路径中，使得膜的第一表面在收缩期间与天然小叶相邻，并且膜的第二表面在收缩期间与另一个天然小叶邻接，从而减少心脏瓣膜反流。

公开(公告)号：US20140005774A9

公开(公告)日：2014-01-02

申请号：US13010010

申请日：2011-01-20

Applicant: Jacques SEGUIN ,  Georg Börtlein

Inventor： Jacques SEGUIN ,  Georg Börtlein

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61B17/0218 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2210/0023 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0003 ,  A61F2250/0039 ,  A61F2250/0048 ,  A61F2250/0069 ,  Y10S623/904

Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.

Abstract translation: 一种用于替换缺陷天然瓣膜的人工瓣膜组件包括支撑在可扩张瓣膜支架上的置换瓣膜。 如果需要，可以使用一个或多个锚。 完全支撑瓣膜环，瓣膜小叶和瓣膜关节点的瓣膜支撑件被构造为可折叠的，用于经腔输送，并且当组件被适当定位时，其可扩张以接触天然瓣膜的解剖环。 当膨胀时，锚固件接合管腔壁，并且当定位就位时防止阀组件的大量迁移。 假体瓣膜组件围绕导管可压缩，并且被外护套限制为扩张。 导管可以插入体内的腔内，例如股动脉，并且被输送到期望的位置，例如心脏。 当外鞘缩回时，假体瓣膜组件膨胀到扩张位置，使得瓣膜和瓣膜支撑件在缺陷的天然瓣膜内膨胀，并且锚固件与腔壁接合。