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公开(公告)号：US08540078B2
公开(公告)日：2013-09-24
申请号：US12758119
申请日：2010-04-12
Applicant: Michael D. Leach , Jason Chavarria
Inventor： Michael D. Leach , Jason Chavarria
CPC classification number: B01D21/262 , A61B2017/00969 , A61M2202/08 , B01D17/0217 , B04B3/00 , B04B5/0442 , B04B11/06
Abstract: Extracting or removing at least a portion of liquid phase from a whole sample using a centrifugal force is disclosed. Centrifugal forces are used to apply pressure to a whole sample and drive a liquid phase through a passage region that can be perforated and/or porous and maintain a drier portion within a separation container. The whole sample can be dried, which includes a remaining sample where excess or a selected amount of liquid is removed. Direct access to the separation container or area can then be made to provide for an efficient withdrawal of the drier material from the separation container.
Abstract translation: 公开了使用离心力从整个样品中提取或去除至少一部分液相。 离心力用于对整个样品施加压力，并将液相驱动通过穿孔和/或多孔的通道区域，并将干燥器部分保持在分离容器内。 整个样品可以被干燥，其中包括剩余的样品，其中除去过量或选定量的液体。 然后可以直接进入分离容器或区域以提供干燥剂材料从分离容器的有效抽出。
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公开(公告)号：US08313954B2
公开(公告)日：2012-11-20
申请号：US12417789
申请日：2009-04-03
Applicant: Michael D. Leach , Jason Chavarria
Inventor： Michael D. Leach , Jason Chavarria
CPC classification number: B01D17/12 , A61M1/029 , A61M2202/0415 , A61M2202/0427 , A61M2202/0429 , A61M2202/0464 , A61M2202/10 , B01L3/0217 , B01L3/50215 , B01L2400/0409 , G01N33/491 , Y10T436/25 , Y10T436/25375 , Y10T436/2575
Abstract: A separation device including a first buoy, a second buoy, a first valve, and a second valve. The first buoy is mounted to a buoy guide post and slidably mounted within a separation chamber. The second buoy is slidably mounted to the guide post and movable between a first position and a second position. The second buoy closes the first valve and opens the second valve when in the first position. The second buoy opens the first valve and closes the second valve when in the second position. The second buoy has a density such that after spinning the device for a suitable period of time a first component of the composition is isolated between the first buoy and the second buoy and a second component of the composition is isolated between the second buoy and the end of the separation chamber that is opposite to a port.
Abstract translation: 一种分离装置，包括第一浮标，第二浮标，第一阀和第二阀。 第一浮标安装在浮标导向柱上并可滑动地安装在分离室内。 第二浮标可滑动地安装到引导柱上，并可在第一位置和第二位置之间移动。 第二个浮标关闭第一个阀，并在第一个位置打开第二个阀。 第二个浮标打开第一个阀，并在第二个位置关闭第二个阀。 第二浮标具有密度，使得在将装置旋转适当的时间段之后，组合物的第一组分在第一浮标和第二浮标之间分离，并且组合物的第二组分在第二浮标和末端之间被隔离 与分离室相对。
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公开(公告)号：US20100256595A1
公开(公告)日：2010-10-07
申请号：US12417789
申请日：2009-04-03
Applicant: Michael D. Leach , Jason Chavarria
Inventor： Michael D. Leach , Jason Chavarria
CPC classification number: B01D17/12 , A61M1/029 , A61M2202/0415 , A61M2202/0427 , A61M2202/0429 , A61M2202/0464 , A61M2202/10 , B01L3/0217 , B01L3/50215 , B01L2400/0409 , G01N33/491 , Y10T436/25 , Y10T436/25375 , Y10T436/2575
Abstract: A separation device including a first buoy, a second buoy, a first valve, and a second valve. The first buoy is mounted to a buoy guide post and slidably mounted within a separation chamber. The second buoy is slidably mounted to the guide post and movable between a first position and a second position. The second buoy closes the first valve and opens the second valve when in the first position. The second buoy opens the first valve and closes the second valve when in the second position. The second buoy has a density such that after spinning the device for a suitable period of time a first component of the composition is isolated between the first buoy and the second buoy and a second component of the composition is isolated between the second buoy and the end of the separation chamber that is opposite to a port.
Abstract translation: 一种分离装置，包括第一浮标，第二浮标，第一阀和第二阀。 第一浮标安装在浮标导向柱上并可滑动地安装在分离室内。 第二浮标可滑动地安装到引导柱上，并可在第一位置和第二位置之间移动。 第二个浮标关闭第一个阀，并在第一个位置打开第二个阀。 第二个浮标打开第一个阀，并在第二个位置关闭第二个阀。 第二浮标具有密度，使得在将装置旋转适当的时间段之后，组合物的第一组分在第一浮标和第二浮标之间分离，并且组合物的第二组分在第二浮标和末端之间被隔离 与分离室相对。
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公开(公告)号：US09011800B2
公开(公告)日：2015-04-21
申请号：US12504413
申请日：2009-07-16
Applicant: Michael D. Leach , Jason Chavarria
Inventor： Michael D. Leach , Jason Chavarria
CPC classification number: A61M1/029 , A61M1/3693 , A61M2202/0437 , A61M2202/10 , B01D21/262 , B01D21/307 , B01D2221/10
Abstract: According to various embodiments, a system can be provided to separate undifferentiated cells and/or stromal cells from a whole tissue sample. The whole tissue sample can be any appropriate tissue sample obtained directly from a patient. The tissue sample can be obtained during a selected operating procedure for immediate or quick application or re-application to the patient. Accordingly, autologous cells can be obtained intraoperatively for application to a patient substantially soon after obtaining a whole tissue sample.
Abstract translation: 根据各种实施方案，可以提供系统以从整个组织样品中分离未分化的细胞和/或基质细胞。 整个组织样本可以是直接从患者获得的任何合适的组织样本。 可以在选择的操作程序期间获得组织样品，以立即或快速施用或重新施用于患者。 因此，在获得整个组织样本之后，可以在术中基本上很快获得自体细胞以供给患者。
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公开(公告)号：US08486076B2
公开(公告)日：2013-07-16
申请号：US13016404
申请日：2011-01-28
Applicant: Jason Chavarria , Matthew T. Stone
Inventor： Jason Chavarria , Matthew T. Stone
IPC: A61B17/00
CPC classification number: A61B17/1684 , A61B17/1659 , A61B17/1735 , A61B17/1778 , A61B2090/036
Abstract: Oscillating rasps for the surgical preparation of the bone prior to the implantation of a glenoid or acetabular component with complex geometry are disclosed. Surgical methods for the use of such oscillating rasps are also disclosed. The oscillating rasp includes an attachment head configured to be secured in a chuck of an oscillating tool, and a cutting head secured to the attachment head. The cutting head includes a cutting surface extending posteriorly from the longitudinal axis of the oscillating surgical rasp. The cutting surface has a plurality of cutting teeth arranged in a geometry that, when oscillated along a predetermined path in contact with the glenoid of the patient, corresponds with the geometry of the augmented glenoid prosthesis.
Abstract translation: 公开了在植入具有复杂几何形状的关节盂或髋臼部件之前进行骨的手术准备的摆动锉。 还公开了使用这种摆动锉的手术方法。 振动锉刀包括被配置为固定在摆动工具的卡盘中的连接头和固定到附接头上的切割头。 切割头包括从摆动外科锉刀的纵向轴线向后延伸的切割表面。 切割表面具有多个切割齿，所述切割齿以几何形状布置，当沿着与患者的关节盂接触的预定路径摆动时，该切割齿对应于增大关节盂假体的几何形状。
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Patent Agency Ranking
公开(公告)号：US20100317099A1
公开(公告)日：2010-12-16
申请号：US12758119
申请日：2010-04-12
Applicant: Michael D. Leach , Jason Chavarria
Inventor： Michael D. Leach , Jason Chavarria
IPC: C12N5/0775 , C12M1/10
CPC classification number: B01D21/262 , A61B2017/00969 , A61M2202/08 , B01D17/0217 , B04B3/00 , B04B5/0442 , B04B11/06
Abstract: Extracting or removing at least a portion of liquid phase from a whole sample using a centrifugal force is disclosed. Centrifugal forces are used to apply pressure to a whole sample and drive a liquid phase through a passage region that can be perforated and/or porous and maintain a drier portion within a separation container. The whole sample can be dried, which includes a remaining sample where excess or a selected amount of liquid is removed. Direct access to the separation container or area can then be made to provide for an efficient withdrawal of the drier material from the separation container.
Abstract translation: 公开了使用离心力从整个样品中提取或去除至少一部分液相。 离心力用于对整个样品施加压力，并将液相驱动通过可穿孔和/或多孔的通道区域，并将干燥器部分保持在分离容器内。 整个样品可以被干燥，其中包括剩余的样品，其中除去过量或选定量的液体。 然后可以直接进入分离容器或区域以提供干燥剂材料从分离容器的有效抽出。
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公开(公告)号：US08337711B2
公开(公告)日：2012-12-25
申请号：US12395085
申请日：2009-02-27
Applicant: Randel Dorian , Michael D. Leach , Richard W. Storrs , Jason Chavarria
Inventor： Randel Dorian , Michael D. Leach , Richard W. Storrs , Jason Chavarria
CPC classification number: C12M47/04 , B01L3/5021 , B01L3/50825 , B01L3/5635 , B01L2200/026 , B01L2300/046 , C12M47/02 , G01N1/286 , G01N1/4077
Abstract: Disclosed is a system to separate, enrich, and/or purify a cellular population from a biological tissue, such as a tissue sample. For example, an adipose tissue sample can be acquired and disrupted. The disrupted tissue sample can then be separated and purified. The separated components can include multipotent, pluripotent, or other cell populations.
Abstract translation: 公开了从生物组织如组织样品分离，富集和/或纯化细胞群的系统。 例如，可以获取并破坏脂肪组织样品。 然后可以分离和纯化破碎的组织样品。 分离的组分可以包括多能，多能或其他细胞群体。
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公开(公告)号：US08182769B2
公开(公告)日：2012-05-22
申请号：US12062817
申请日：2008-04-04
Applicant: Jason Chavarria
Inventor： Jason Chavarria
CPC classification number: B65B69/00 , B01L3/5021 , B01L3/508 , B01L9/06 , B01L2200/025 , B01L2200/141 , B01L2300/041 , B01L2300/0832 , B01L2400/0409 , Y10T436/2525 , Y10T436/25375
Abstract: A transportation system for transporting a biological material container between a sterile field and a nonsterile field and substantially maintaining sterility of the biological material container includes a housing assembly that removably houses the biological material container. The system also includes a port defined by the housing assembly, and the port provides communication into the biological material container from outside the housing assembly. The housing assembly includes a first member that covers a first portion of the biological material container such that a second portion of the biological material container extends from the first member. The housing assembly also includes a second member that covers the second portion of the biological material container. The second member is removably coupled to the first member to expose the second portion of the biological material container. A keying member that keys the transportation system in a centrifuge is also disclosed.
Abstract translation: 用于在无菌场和非无菌场之间运输生物材料容器并且基本上保持生物材料容器的无菌性的运输系统包括可移除地容纳生物材料容器的壳体组件。 该系统还包括由壳体组件限定的端口，并且该端口从壳体组件的外部提供到生物材料容器的连通。 壳体组件包括覆盖生物材料容器的第一部分的第一构件，使得生物材料容器的第二部分从第一构件延伸。 壳体组件还包括覆盖生物材料容器的第二部分的第二构件。 第二构件可移除地联接到第一构件以暴露生物材料容器的第二部分。 还公开了将离心机中的运输系统关键的键控构件。
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9.发明申请公开(公告)号：US20100106138A1
公开(公告)日：2010-04-29
申请号：US12260541
申请日：2008-10-29
Applicant: Jason Chavarria
Inventor： Jason Chavarria
IPC: A61M5/31
CPC classification number: A61B17/00491 , A61B2017/00495
Abstract: A system for expressing two materials onto a selected site is disclosed. The system can include a syringe that is operable to maintain two separated materials substantially separate until a selected time. The system can further include a tip portion operable to direct the two materials, either mixed or unmixed, to a selected site. The materials can include tissue sealants, growth factors, or other appropriate materials to be directed to a selected site.
Abstract translation: 公开了一种将两种材料表现在所选择的部位上的系统。 该系统可以包括可操作以将两个分离的材料基本上分离直到选定的时间的注射器。 该系统还可以包括可操作以将两种混合或不混合的材料引导到选定部位的尖端部分。 这些材料可以包括组织密封剂，生长因子或要被引导到选定部位的其它合适的材料。
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公开(公告)号：US20090253566A1
公开(公告)日：2009-10-08
申请号：US12062817
申请日：2008-04-04
Applicant: Jason Chavarria
Inventor： Jason Chavarria
CPC classification number: B65B69/00 , B01L3/5021 , B01L3/508 , B01L9/06 , B01L2200/025 , B01L2200/141 , B01L2300/041 , B01L2300/0832 , B01L2400/0409 , Y10T436/2525 , Y10T436/25375
Abstract: A transportation system for transporting a biological material container between a sterile field and a nonsterile field and substantially maintaining sterility of the biological material container includes a housing assembly that removably houses the biological material container. The system also includes a port defined by the housing assembly, and the port provides communication into the biological material container from outside the housing assembly. The housing assembly includes a first member that covers a first portion of the biological material container such that a second portion of the biological material container extends from the first member. The housing assembly also includes a second member that covers the second portion of the biological material container. The second member is removably coupled to the first member to expose the second portion of the biological material container. A keying member that keys the transportation system in a centrifuge is also disclosed.
Abstract translation: 用于在无菌场和非无菌场之间运输生物材料容器并且基本上保持生物材料容器的无菌性的运输系统包括可移除地容纳生物材料容器的壳体组件。 该系统还包括由壳体组件限定的端口，并且该端口从壳体组件的外部提供到生物材料容器的连通。 壳体组件包括覆盖生物材料容器的第一部分的第一构件，使得生物材料容器的第二部分从第一构件延伸。 壳体组件还包括覆盖生物材料容器的第二部分的第二构件。 第二构件可移除地联接到第一构件以暴露生物材料容器的第二部分。 还公开了将离心机中的运输系统关键的键控构件。
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