公开(公告)号：US20200061041A1

公开(公告)日：2020-02-27

申请号：US16289311

申请日：2019-02-28

申请人： Zacharia Cheruvallath ,  Jason Green ,  Ben Johnson ,  Kristin Schleicher ,  Huikai Sun ,  Mingnam Tang ,  Takeda Pharmaceutical Company Limited

发明人： Zacharia Cheruvallath ,  Jason Green ,  Ben Johnson ,  Kristin Schleicher ,  Huikai Sun ,  Mingnam Tang

IPC分类号： A61K31/4439 ,  C07D401/12 ,  A61K31/4545 ,  C07D403/12 ,  A61K31/506 ,  C07D401/14 ,  A61K31/40 ,  C07D207/14 ,  C07D211/58 ,  A61K31/4468 ,  A61K31/501 ,  A61K31/497 ,  A61K31/4355 ,  C07D491/048 ,  A61K31/438

摘要： Disclosed are compounds of Formula 1, stereoisomers thereof, and pharmaceutically acceptable salts thereof, wherein L, r, s, R5, R6, R7, R9, R10, R11, R12, X1, X2, X3, X4, X13, and X14 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating diseases, disorders, and conditions associated with SSTR4.

公开(公告)号：US09428047B2

公开(公告)日：2016-08-30

申请号：US14520848

申请日：2014-10-22

申请人： Jason Green

发明人： Jason Green

IPC分类号： B60K15/03 ,  B60K15/063 ,  B60K15/067 ,  B60K15/05

CPC分类号： B60K15/063 ,  B60K15/05 ,  B60K15/067 ,  B60K15/07 ,  B60K2015/03355 ,  B60K2015/0634 ,  B60Y2200/142

摘要： A system and attendant assembly for incorporating at least one alternate fuel supply, such as of the type used in combination with a conventional distillate fuel, to power a heavy duty industrial vehicle, such as a mine haul dump truck. The system and attendant assembly includes a mounting assembly structured for containment and support of a primary fuel tank and an auxiliary fuel tank. The mounting assembly is disposed on a mounting area laterally adjacent between the two tires on a side of the truck, wherein the mounting assembly and mounting area are cooperatively disposed and structured to facilitate storage of the alternate fuel and operative communication and distribution thereof with the powering operations of the vehicle.

摘要翻译： 用于将至少一种替代燃料供应（例如与常规馏出燃料组合使用的类型）相结合的系统和服务员组件为重型工业车辆（例如矿井运输自卸车）供电。 系统和服务员组件包括构造成用于容纳和支撑主燃料箱和辅助燃料箱的安装组件。 安装组件设置在横向相邻于卡车侧面的两个轮胎之间的安装区域上，其中安装组件和安装区域被协同地设置和构造，以便于备用燃料的存储和与其的动力连通和分配 车辆的作业。

公开(公告)号：US09248736B2

公开(公告)日：2016-02-02

申请号：US13234995

申请日：2011-09-16

申请人： Jason Green

发明人： Jason Green

IPC分类号： B60K15/067 ,  B60K15/063 ,  B60K15/07 ,  B66F9/07 ,  F02M37/00 ,  B60P1/00

CPC分类号： B60K15/063 ,  B60K15/067 ,  B60K15/07 ,  B60K2015/0637 ,  B60P1/00 ,  B60Y2200/142 ,  B66F9/07 ,  F02M37/00

摘要： A system and attendant structural components for incorporating an alternate fuel supply, such as of the type used in combination with a conventional distillate fuel, to power a heavy duty industrial vehicle, such as a mine haul dump truck. The system and attendant structure includes a mounting assembly structured for containment and support of the alternate fuel and a containment area disposed on the vehicle and structured and dimensioned to retain the mounting assembly therein. The containment area and the mounting assembly are disposed in laterally adjacent, exposed relation to an operator area of the mine haul truck, wherein the mounting assembly and the containment area are cooperatively disposed and structured to facilitate storage of the alternate fuel and operative communication and distribution thereof with the powering engine of the mine haul vehicle.

摘要翻译： 用于结合替代燃料供应的系统和附属结构部件，例如与常规馏出燃料组合使用的类型的燃料，为重型工业车辆，例如矿井自卸车提供动力。 系统和服务员结构包括构造成用于容纳和支撑替代燃料的安装组件和设置在车辆上的结构和尺寸，以将安装组件保持在其中。 容纳区域和安装组件与矿井运输车辆的操作者区域横向相邻暴露的关系设置，其中安装组件和容纳区域协同地设置和构造以便于替代燃料的储存和操作性通信和分配 与矿山运输车辆的动力发动机。

公开(公告)号：USD723582S1

公开(公告)日：2015-03-03

申请号：US29449783

申请日：2013-03-15

申请人： Jason Green ,  Kerry Hackney ,  Chert Nompone

设计人： Jason Green ,  Kerry Hackney ,  Chert Nompone

公开(公告)号：US20150000643A1

公开(公告)日：2015-01-01

申请号：US14295969

申请日：2014-06-04

申请人： Jason Green ,  Glenn Juber ,  Chert Nompone

发明人： Jason Green ,  Glenn Juber ,  Chert Nompone

IPC分类号： F02B43/10 ,  F02M43/00

CPC分类号： F02M21/0215 ,  F02B2043/103 ,  F02M21/029 ,  F02M21/06 ,  Y02T10/32 ,  Y02T10/36

摘要： A system designed and structured to fully integrate LNG conversion solution for power plants associated with locomotives, which include, but are not limited to, General Electric AC 4400 and Dash-9 locomotive power plants.

摘要翻译： 一个设计和结构的系统，用于将与机车有关的发电厂的LNG转换解决方案完全整合，其中包括但不限于通用电气AC 4400和Dash-9机车发电厂。

公开(公告)号：US20130069357A1

公开(公告)日：2013-03-21

申请号：US13478885

申请日：2012-05-23

申请人： Jason Green

发明人： Jason Green

IPC分类号： B60K15/067 ,  F16M13/02

CPC分类号： B60K15/067 ,  B60K15/07 ,  B60Y2200/142 ,  F16M13/02

摘要： A system and attendant structural components for incorporating an alternate fuel supply, such as of the type used in combination with a conventional distillate fuel, to power a heavy duty industrial vehicle, such as a mine haul dump truck. The system and attendant structure includes a mounting assembly structured for containment and support of the alternate fuel and a containment area disposed on the vehicle and structured and dimensioned to retain the mounting assembly therein. The containment area and the mounting assembly are disposed in laterally adjacent, exposed relation to an operator area of the mine haul truck, wherein the mounting assembly and the containment area are cooperatively disposed and structured to facilitate storage of the alternate fuel and operative communication and distribution thereof with the powering engine of the mine haul vehicle.

公开(公告)号：US08366526B2

公开(公告)日：2013-02-05

申请号：US12761888

申请日：2010-04-16

申请人： Nick Baynes ,  David Jefferies ,  Jason Green ,  Serkan Hassan

发明人： Nick Baynes ,  David Jefferies ,  Jason Green ,  Serkan Hassan

IPC分类号： A63F9/24

CPC分类号： A63F13/803 ,  A63F13/537 ,  A63F13/60 ,  A63F2300/609 ,  A63F2300/8017

摘要： Method, article and apparatus for executing computer games, and in particular, computer-based racing games. In a racing game, a player may be allowed to earn one or more game play options which may be exercised during the race. The game play options, when exercised, may modify the predefined race path to create an advantage for the player or a disadvantage to the competitors.

摘要翻译： 用于执行电脑游戏的方法，文章和装置，特别是基于计算机的赛车游戏。 在赛车游戏中，可允许玩家获得一个或多个在比赛期间可以行使的游戏选项。 游戏选项在行使时可能会修改预定义的比赛路径，为玩家创造优势或竞争对手的劣势。

公开(公告)号：US08110397B2

公开(公告)日：2012-02-07

申请号：US12172144

申请日：2008-07-11

申请人： Douglas Jason Green

发明人： Douglas Jason Green

IPC分类号： C12M1/26 ,  C12M3/00

CPC分类号： G01N1/28 ,  B01F15/0205 ,  B01F15/0212 ,  B01F15/0223 ,  B01L3/502 ,  B01L2200/0647 ,  B01L2200/16 ,  B01L2400/0683 ,  G01N1/02 ,  G01N2001/007 ,  G01N2001/027 ,  G01N2001/028 ,  Y02P20/582

摘要： A reconfigurable sample preparation device includes a rotary plunger device having a hollow body and a coupling device, provided above one end of the rotary plunger, and accommodating a sample. The device also includes at least one sealed reagent module. When the rotary plunger is rotated on the coupling device, a film of the reagent module is pierced, mixing the sample with a substance from the reagent module.

摘要翻译： 可重构样品制备装置包括具有中空体的旋转柱塞装置和设置在旋转柱塞的一端上方并且容纳样品的联接装置。 该装置还包括至少一个密封的试剂模块。 当旋转柱塞在耦合装置上旋转时，刺穿试剂模块的膜，将样品与来自试剂模块的物质混合。

公开(公告)号：US20100192706A1

公开(公告)日：2010-08-05

申请号：US12449855

申请日：2008-02-28

申请人： Michael Roy Fairs ,  Thomas David Ford ,  Piers Sebastian Harding ,  Gary Stephen Howard ,  Barry Boyes ,  John Walter Czajka ,  Douglas Jason Green ,  Jay Lewington ,  Carmelo Volpe ,  Colin Fewster ,  Jason Betley ,  Catherine Mills ,  William Richard Mawer

发明人： Michael Roy Fairs ,  Thomas David Ford ,  Piers Sebastian Harding ,  Gary Stephen Howard ,  Barry Boyes ,  John Walter Czajka ,  Douglas Jason Green ,  Jay Lewington ,  Carmelo Volpe ,  Colin Fewster ,  Jason Betley ,  Catherine Mills ,  William Richard Mawer

IPC分类号： G01N1/10

CPC分类号： G01N1/28 ,  B01L3/502 ,  B01L3/5082 ,  B01L2300/046 ,  B01L2300/0681 ,  B01L2300/087 ,  B01L2400/0683 ,  G01N2035/1086

摘要： Apparatus for preparing a biological sample for PCR analysis has an inlet (4) for receiving the sample (15) and a sieve (13) through which the sample is forced by screwing down an inlet cap (16). A lysis solution between two rupturable seals (11 and 12) is effective to disrupt the cells of the sample and release nucleic acid. The apparatus is mounted releasably on a PCR machine (2) having a motor (2′) releasably coupled with a drive mechanism (3, 36,40) in the apparatus to effect a rotary and a vertical up and down movement of its components (30, 31, 32, 42). The apparatus has a transparent cuvette (5) and a needle (71) extending to the lower end of the cuvette, by which the prepared sample is dispensed to the cuvette for PCR analysis.

摘要翻译： 用于制备用于PCR分析的生物样品的装置具有用于接收样品（15）的入口（4）和通过拧入入口盖（16）来迫使样品被迫的筛子。 两个可破裂的密封件（11和12）之间的裂解溶液有效地破坏样品的细胞并释放核酸。 该装置可释放地安装在具有可释放地与设备中的驱动机构（3,36,40）联接的马达（2'）的PCR机（2）上，以实现其部件的旋转和垂直上下运动 30，31，32，42）。 该装置具有透明比色皿（5）和延伸到比色皿下端的针（71），通过该针将准备的样品分配到比色皿进行PCR分析。

公开(公告)号：US20090079975A1

公开(公告)日：2009-03-26

申请号：US12172142

申请日：2008-07-11

申请人： Douglas Jason Green ,  Jordan Fields

发明人： Douglas Jason Green ,  Jordan Fields

IPC分类号： G01N21/01

CPC分类号： G02B6/4201 ,  G01N21/645 ,  G01N2021/6484 ,  G02B6/424 ,  G02B6/4246 ,  G02B6/4257 ,  G02B6/4261 ,  G02B6/4268 ,  G02B6/4269 ,  G02B6/4286 ,  G02B6/4292

摘要： A sealed and decontaminated fiber optic detection apparatus includes an optics portion with individual chambers. Each chamber housing optical and electro-optical components. A manifold accommodates fibers, with each of the fibers being in optical communication with the optical and electro-optical components of a corresponding chamber. The apparatus also includes a sample holder that holds a sample to be tested and a mounting device provided between the sample holder and the manifold. The mounting device and the manifold form a sealed fiber optic interface between the sample holder and the optics portion.

摘要翻译： 密封和净化的光纤检测装置包括具有各个室的光学部分。 每个腔室都容纳光学和电光元件。 歧管容纳纤维，其中每个纤维与相应室的光学和电光学部件光学连通。 该装置还包括保持待测试样品的样品架和设置在样品保持器和歧管之间的安装装置。 安装装置和歧管在样品保持器和光学部件之间形成密封的光纤接口。