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1.发明申请METHOD FOR OBTAINING MASTOCYTE LINES FROM PIG TISSUES AND FOR PRODUCING HEPARIN-TYPE MODULES 审中-公开用于从皮组织获得骨髓细胞生产线和用于生产肝细胞模型的方法公开(公告)号：US20080064095A1
公开(公告)日：2008-03-13
申请号：US11938422
申请日：2007-11-12
申请人： Jean-Marc GUILLAUME , Werner DITTRICH , Sandrine PEREZ , Christine Michelle ANDREONI , Romain PAILLOT
发明人： Jean-Marc GUILLAUME , Werner DITTRICH , Sandrine PEREZ , Christine Michelle ANDREONI , Romain PAILLOT
IPC分类号： C12N5/00
CPC分类号： C07K14/71 , C12N5/0642 , C12N9/16 , C12N2501/125 , C12N2501/22 , C12N2501/23 , C12N2510/02 , C12N2510/04 , C12P19/26 , C12P19/28
摘要： The present application relates to a method for obtaining mastocyte cultures or lines. It also relates to a method for producing heparin-type molecules, comprising the culturing of mastocyte cultures or lines.
摘要翻译： 本申请涉及获得肥大细胞培养物或细胞系的方法。 它还涉及一种生产肝素型分子的方法，其包括培养肥大细胞培养物或细胞系。
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2.发明申请Method for obtaining mastocyte lines from pig tissues and for producing heparin-type molecules 审中-公开从猪组织获得肥大细胞系和产生肝素型分子的方法公开(公告)号：US20050181484A1
公开(公告)日：2005-08-18
申请号：US10823142
申请日：2004-04-13
IPC分类号： C07K14/71 , C12N5/02 , C12N5/0787 , C12N9/16 , C12N15/12 , C12N15/55 , C12P19/26 , C12P19/28 , C12N5/08
CPC分类号： C07K14/71 , C12N5/0642 , C12N9/16 , C12N2501/125 , C12N2501/22 , C12N2501/23 , C12N2510/02 , C12N2510/04 , C12P19/26 , C12P19/28
摘要： The present application relates to a method for obtaining mastocyte cultures or lines. It also relates to a method for producing heparin-type molecules, comprising the culturing of mastocyte cultures or lines.
摘要翻译： 本申请涉及一种获得肥大细胞培养物或细胞系的方法。 它还涉及一种生产肝素型分子的方法，其包括培养肥大细胞培养物或细胞系。
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3.发明授权Analytical system and method for assessing certain characteristics of organizations 有权用于评估组织某些特征的分析系统和方法公开(公告)号：US09569729B1
公开(公告)日：2017-02-14
申请号：US15215570
申请日：2016-07-20
申请人： Richard Oehrle , Steven Lee Roberts , Elizabeth B Charnock , Katya Saint-Amand , Laurent Jean-Marc Guillaume Dupont
发明人： Richard Oehrle , Steven Lee Roberts , Elizabeth B Charnock , Katya Saint-Amand , Laurent Jean-Marc Guillaume Dupont
CPC分类号： G06Q10/063
摘要： A computer readable medium for analyzing and predicting the future behavior of organizations is disclosed. An embodiment of this invention is comprised of one or more repositories of data which involve comments or other actions by actors with some kind of relationship to a target organization, a repository of metadata relating to this data, a repository of updatable models of organizations, a natural language parsing engine, and an engine for generating and comparing the organizational models.
摘要翻译： 公开了一种用于分析和预测组织未来行为的计算机可读介质。 本发明的实施例包括一个或多个数据存储库，其涉及与目标组织具有某种关系的参与者的注释或其他动作，与该数据相关的元数据库，组织可更新模型的存储库， 自然语言解析引擎，以及用于生成和比较组织模型的引擎。
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公开(公告)号：US20050287657A1
公开(公告)日：2005-12-29
申请号：US11086678
申请日：2005-03-23
IPC分类号： C12N15/09 , A61K35/76 , A61K48/00 , B01D15/08 , B01D61/14 , B01J41/20 , C12N7/01 , C12N7/02 , C12N15/86 , C12N15/861 , G01N30/02
CPC分类号： C12N7/00 , B01D15/363 , B01D61/145 , B01J41/20 , C12N15/86 , C12N2710/10343 , C12N2710/10351 , G01N30/02
摘要： The invention concerns a method for producing recombinant adenovirus by which viral DNA is introduced in a packaging cell culture and the viruses produced are harvested after liberation in the supernatant. The invention also concerns the viruses produced and their use.
摘要翻译： 本发明涉及生产重组腺病毒的方法，通过该方法将病毒DNA引入包装细胞培养物中，并且在上清液中释放后收获产生的病毒。 本发明还涉及所产生的病毒及其用途。
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公开(公告)号：US20180189691A1
公开(公告)日：2018-07-05
申请号：US15397737
申请日：2017-01-04
摘要： A computer readable medium for analyzing and predicting the future behavior of organizations is disclosed. An embodiment of this invention is comprised of one or more repositories of data which involve comments or other actions by actors with some kind of relationship to a target organization, a repository of metadata relating to this data, a repository of updatable models of organizations, a natural language parsing engine, an engine for generating and comparing the organizational models, and presentations of avatars.
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公开(公告)号：US06905862B2
公开(公告)日：2005-06-14
申请号：US10267865
申请日：2002-10-10
IPC分类号： C12N15/09 , A61K35/76 , A61K48/00 , B01D15/08 , B01D61/14 , B01J41/20 , C12N7/01 , C12N7/02 , C12N15/86 , C12N15/861 , G01N30/02
CPC分类号： C12N7/00 , B01D15/363 , B01D61/145 , B01J41/20 , C12N15/86 , C12N2710/10343 , C12N2710/10351 , G01N30/02
摘要： The invention concerns a method for producing recombinant adenovirus by which viral DNA is introduced in a packaging cell culture and the viruses produced are harvested after liberation in the supernatant. The invention also concerns the viruses produced and their use.
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公开(公告)号：US10445668B2
公开(公告)日：2019-10-15
申请号：US15397737
申请日：2017-01-04
摘要： A computer readable medium for analyzing and predicting the future behavior of Organizations, where an embodiment of this invention is comprised of one or more repositories of data which involve comments or other actions by actors with some kind of relationship to a target organization, a repository of metadata relating to this data, a repository of updatable models of organizations, a natural language parsing engine, an engine for generating and comparing the organizational models, and presentations of avatars.
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公开(公告)号：US06485958B2
公开(公告)日：2002-11-26
申请号：US09202545
申请日：1998-12-16
IPC分类号： C12N702
CPC分类号： C12N7/00 , B01D15/363 , B01D61/145 , B01J41/20 , C12N15/86 , C12N2710/10343 , C12N2710/10351 , G01N30/02
摘要： The invention concerns a method for producing recombinant adenovirus by which viral DNA is introduced in a packaging cell culture and the viruses produced are harvested after liberation in the supernatant. The invention also concerns the viruses produced and their use.
摘要翻译： 本发明涉及生产重组腺病毒的方法，通过该方法将病毒DNA引入包装细胞培养物中，并且在上清液中释放后收获产生的病毒。 本发明还涉及所产生的病毒及其用途。
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9.发明授权Perhydroisoindole derivatives, preparation thereof and pharmaceutical compositions containing same 失效全氢异吲哚衍生物，其制备方法和含有它们的药物组合物
公开(公告)号：US5631279A
公开(公告)日：1997-05-20
申请号：US448402
申请日：1995-06-07
申请人： Andre Crespo , Veronique Fardin , Jean-Marc Guillaume , Jean-Luc Malleron , Jean-Francois Peyronel
发明人： Andre Crespo , Veronique Fardin , Jean-Marc Guillaume , Jean-Luc Malleron , Jean-Francois Peyronel
IPC分类号： A61K31/40 , A61K31/403 , A61K31/4035 , A61P1/00 , A61P9/08 , A61P11/00 , A61P13/02 , A61P15/00 , A61P25/04 , A61P29/00 , A61P43/00 , C07D209/44 , C07D403/06
CPC分类号： C07D403/06 , C07D209/44
摘要： This invention relates to perhydroisoindole derivatives of 08/448,402 formula (I), wherein radicals R are phenyl radicals optionally 2-or 3-substituted by a halogen atom or a methyl radical; R.sub.1 is optionally substituted phenyl, cyclohexadienyl, naphthyl, indenyl or optionally substituted heterocyclyl; R.sub.2 is H, halogen, OH, alkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkoxy, alkylthio, acyloxy, acyloxy, carboxy, optionally substituted alkyloxycarbonyl, benzyloxycarbonyl, amino or acylamino; and R.sub.3 is optionally 2-substituted phenyl; optionally salts thereof where applicable; and preparation thereof. Said derivatives are particularly useful as neurokinin A antagonists. ##STR1##
摘要翻译： PCT No.PCT / FR94 / 00371 Sec。 371日期：1995年6月7日 102（e）日期1995年6月7日PCT 1994年4月1日PCT PCT。 第WO94 / 22822号公报 日本特开1994年10月13日本发明涉及08 / 448,402式（I）的全氢异吲哚衍生物，其中基团R是任选被卤素原子或甲基取代的2-或3-取代的苯基; R1是任选取代的苯基，环己二烯基，萘基，茚基或任选取代的杂环基; R 2是H，卤素，OH，烷基，氨基烷基，烷基氨基烷基，二烷基氨基烷基，烷氧基，烷硫基，酰氧基，酰氧基，羧基，任选取代的烷氧基羰基，苄氧羰基，氨基或酰氨基; 并且R 3是任选的2-取代的苯基; 任选的盐; 及其制备。 所述衍生物特别可用作神经激肽A拮抗剂。 （一）
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公开(公告)号：US20050042733A1
公开(公告)日：2005-02-24
申请号：US10492200
申请日：2002-10-22
申请人： Pierre Cans , Jean-Marc Guillaume , Helene Rigal
发明人： Pierre Cans , Jean-Marc Guillaume , Helene Rigal
IPC分类号： A61K31/727 , A61P7/02 , C08B37/00 , C08B37/10 , C12P19/26
CPC分类号： C12P19/26 , C08B37/0075
摘要： The invention concerns the production of heparin from mast cell cultures, in particular pig mast cells.
摘要翻译： 本发明涉及从肥大细胞培养物，特别是猪肥细胞中产生肝素。
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