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公开(公告)号：US1741934A
公开(公告)日：1929-12-31
申请号：US21617627
申请日：1927-08-29
申请人： JOHN F HOLLAND , WILLIAM F HOLLAND
发明人： WALTER HARDEN
IPC分类号： G10H3/18
CPC分类号： G10H3/185 , G10H2220/471 , G10H2220/495
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2.发明授权Time-of-flight mass spectrometer combining fields non-linear in time and space 有权飞行时间质谱仪在时间和空间上组合非线性场公开(公告)号：US07372021B2
公开(公告)日：2008-05-13
申请号：US11352301
申请日：2006-02-13
摘要： A time-of-flight mass spectrometer which has an iron source, an evacuated tube proximate the ion source and adapted to receive ions from the ion source, and a detector disposed at an end of the evacuated tube opposite an end proximate the ion source. The ion source is constructed to generate an electric field that changes non-linearly as a function of position along a path from the ion source to the detector. The ion source is constructed to generate an electric field that changes as a function of time, the electric field being provided to accelerate ions from the ion source to the detector.
摘要翻译： 飞行时间质谱仪，其具有铁源，靠近离子源的真空管，并适于接收离子源的离子;以及检测器，设置在与靠近离子源的端部相对的真空管的端部处。 离子源被构造成产生电场，该电场作为沿着从离子源到检测器的路径的位置的函数而非线性地变化。 离子源被构造成产生随时间变化的电场，提供电场以加速离子从离子源到检测器的离子。
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公开(公告)号：US4624915A
公开(公告)日：1986-11-25
申请号：US513995
申请日：1983-07-14
CPC分类号： B07C5/342 , C12M47/04 , C12M47/06 , G01N2015/149
摘要： A method and apparatus for position selection of viable cells based upon differing chemical or physical properties or dynamic processes using a focussed radiant energy beam, such as a laser beam (11) to kill unwanted cells or to isolate wanted cells is described. The apparatus includes microscope means (14) and cell detection means (27) for identifying the cells to be killed or saved and attenuator means (12) for modifying the beam to prevent destruction of cells to be saved.
摘要翻译： 描述了基于使用聚焦辐射能束（例如激光束（11））去除不需要的细胞或隔离所需细胞的不同化学或物理特性或动态过程的活细胞位置选择的方法和装置。 该装置包括用于识别待杀死或保存的细胞的显微镜装置（14）和细胞检测装置（27）和用于修改光束的衰减装置（12），以防止要节省的细胞的破坏。
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公开(公告)号：US6119567A
公开(公告)日：2000-09-19
申请号：US891353
申请日：1997-07-10
CPC分类号： B26F3/08 , B26F1/3806
摘要： A method and preferred apparatus (10) to cut a preform material which is biodegradable and preferably dispersible in water, to produce a shaped article, is described. The cut is produced without producing harmful fumes or leaving a harmful residue and preferably without charring at the cut. Preferably, only small amounts of carbon dioxide and water are produced at the cut. Shaped articles which are in sheet or block form or which are for 2-D or 3-D shaped article formation can be produced.
摘要翻译： 描述了一种切割可生物降解且优选分散在水中的预成型材料的方法和优选设备（10），以生产成型制品。 切割产生而不产生有害烟雾或留下有害残留物，优选在切割时不起焦作用。 优选地，在切割处仅产生少量的二氧化碳和水。 可以制造片状或块状的成形制品或用于形成二维或三维形状的制品。
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5.发明授权Method and apparatus for monitoring and indicating the condition of a battery and the related circuitry 失效用于监测和指示电池状况和相关电路的方法和装置
公开(公告)号：US4665370A
公开(公告)日：1987-05-12
申请号：US187415
申请日：1980-09-15
申请人： John F. Holland
发明人： John F. Holland
CPC分类号： G01R19/16542 , G01R31/3682
摘要： A method and apparatus for testing the battery and the related circuitry of an internal combustion automobile every time the vehicle is started. The test is automatic and the results are available for visual interpretation at the discretion of the operator. The cranking motor furnishes the load for the battery and an electronic apparatus automatically measures the condition of the battery every time the engine is started. The battery tester compares the unloaded voltage of the battery with the voltage under load. If the difference is larger than a preset value, or if the voltage drops below a fixed level, an indicator on the dashboard of the vehicle shows that the battery is low in charge, or it is in a faulty condition, or because of faulty conductors its power is not being delivered to the engine.
摘要翻译： 一种用于每次车辆启动时测试内燃机车的电池和相关电路的方法和装置。 测试是自动的，结果可以由操作员自行决定进行视觉解释。 起动马达为电池提供负载，电子设备每次起动时自动测量电池的状态。 电池测试仪将电池的无负载电压与负载电压进行比较。 如果差值大于预设值，或者电压下降到固定水平以下时，车辆仪表板上的指示灯显示电池电量不足或处于故障状态，或由于导体故障 它的动力没有交付给发动机。
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6.发明授权Combination of time resolution and mass dispersive techniques in mass spectrometry 失效时间分辨率和质谱分析技术在质谱中的组合
公开(公告)号：US4472631A
公开(公告)日：1984-09-18
申请号：US385114
申请日：1982-06-04
CPC分类号： H01J49/40 , B01D59/44 , H01J49/004 , H01J49/28
摘要： Time of flight mass spectrometry techniques are simultaneously combined with path-bending spatial dispersion in magnetic- or electric-sector mass spectrometers to improve the mass resolution or, with an ion fragmentation region, to rapidly obtain multidimensional mass spectral data previously only obtainable by tandem mass spectrometry. The instrumentation generates data defining relationships between parent ions and daughter ions produced by fragmentation, metastable or induced, data to differentiate stable from metastable ions, and data to improve mass resolution. The subject time-resolved mass spectrometers can be combined with chromatography apparatus to obtain multidimensional MS/MS-type data during the relatively short duration of a single chromatographic peak.
摘要翻译： 飞行时间质谱技术与磁电或电扇区质谱仪中的路径弯曲空间色散同时组合以改善质量分辨率，或者利用离子碎片区域快速获得以前只能通过串联质量获得的多维质谱数据 光谱测定。 仪器产生的数据定义了通过断裂，亚稳态或诱导产生的亲本离子和子离子之间的关系，数据以区分稳定离子和亚稳态离子，并提供数据以改善质量分辨率。 主题时间分辨质谱仪可以与色谱装置组合，以在单个色谱峰的相对短的持续时间内获得多维MS / MS型数据。
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7.发明授权Integrating transient recorder apparatus for time array detection in time-of-flight mass spectrometry 失效在飞行时间质谱中集成瞬时记录仪用于时间阵列检测
公开(公告)号：US5367162A
公开(公告)日：1994-11-22
申请号：US81731
申请日：1993-06-23
CPC分类号： H01J49/025 , H01J49/40
摘要： An integrating transient recorder for time array detection of ions within an ion source extraction. The arrival times of all ions having various mass-to-charge ratios are calculated and integrating or peak detecting circuitry is activated just prior to the calculated time of arrival of each ion, and then only for a time duration in accordance with a predetermined data collection time window sufficient to enable each ion mass value to be completely measured. An analog-to-digital converter converts the area or peak analog signal for each ion into a corresponding digital signal and outputs the digital signals to a plurality of FIFO buffers. The FIFO buffers are read out for each successive transient by a digital signal processor and summed over a predetermined number of sequential transients in a mass locked registry creating a file of ion intensities versus mass-to-charge ratio of all ions detected. In a preferred embodiment the apparatus includes a mass defect detector which compares the actual arrival time of the ions with the calculated anticipated time of arrival and applies appropriate time delays from a selected one of a plurality of delta-mass tables. This causes the area or peak detection circuity to be turned on either slightly prior to or subsequent to the calculated times of arrival of each of the ions to thus cause each of the ions to be received clearly and completely within each data collection window. Preferred embodiments include combinations of analog or digital peak or area capture and analog or digital successive summations.
摘要翻译： 用于时间阵列检测离子源提取中离子的积分瞬态记录仪。 计算具有各种质荷比的所有离子的到达时间，并且在计算的每个离子的到达时间之前激活积分或峰值检测电路，然后仅根据预定数据收集的持续时间 足以使每个离子质量值完全测量的时间窗。 模数转换器将每个离子的面积或峰值模拟信号转换成相应的数字信号，并将数字信号输出到多个FIFO缓冲器。 通过数字信号处理器对每个连续的瞬态读出FIFO缓冲器，并在质量锁定的注册表中的预定数量的顺序瞬变相加，从而产生离子强度的文件与检测到的所有离子的质荷比。 在优选实施例中，装置包括质量缺陷检测器，其将离子的实际到达时间与计算的预计到达时间进行比较，并从多个delta质量表中选择的一个施加适当的时间延迟。 这导致区域或峰值检测电路在计算出的每个离子的到达时间之前或之后稍微打开，从而使每个离子在每个数据收集窗口内被清楚和完全地接收。 优选实施例包括模拟或数字峰值或区域捕获以及模拟或数字连续求和的组合。
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公开(公告)号：US5175430A
公开(公告)日：1992-12-29
申请号：US702221
申请日：1991-05-17
CPC分类号： G01N30/8624 , G01N30/8679 , G01N30/7206 , G01N30/8631
摘要： A process and apparatus employing the time compression of chromatography in mass spectrometry with array detection in which the time compressed informatioin is deconvoluted by mathematical analysis for recovery of analytical information made inaccessible in the time compression and thereby resulting in a decrease in analysis time and improved component identification without loss of sensitivity.
摘要翻译： 一种使用质谱法进行色谱法时间压缩的方法和装置，其中通过数据分析对时间压缩信息进行解卷积，以便在时间压缩中使得不可接近的分析信息的回收被解卷积，从而导致分析时间的减少和改进的组分 识别而不失灵敏度。
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公开(公告)号：US4702111A
公开(公告)日：1987-10-27
申请号：US851499
申请日：1986-04-01
申请人： John F. Holland
发明人： John F. Holland
IPC分类号： G01N29/04
CPC分类号： G01N29/045 , G01N2291/0238
摘要： An improved non-destructive sonic testing apparatus is disclosed which is specially adapted for use in assessing the integrity of wooden utility poles. In one embodiment, the sonic testing apparatus of the present invention operates to perform a Fourier analysis on a signal which has been transmitted through a pole to be tested. Two or more criteria selected from the group of mode, mean, median and range are then determined for the resulting waveform and compared in order to provide a visual display representative of the condition of the pole being tested. In another embodiment of the present invention a software peak seeking algorithm is utilized to provide an envelope waveform from which successive half lives are determined. The relative time duration for successive half lives are compared to provide an indication of the amount of decay.
摘要翻译： 公开了一种改进的非破坏性声波测试装置，其特别适用于评估木制电线杆的完整性。 在一个实施例中，本发明的声音测试装置用于对通过待测试的极点传输的信号执行傅立叶分析。 然后对于所得到的波形确定从模式，平均值，中值和范围组中选择的两个或更多个标准，并进行比较，以便提供表示正在测试的极点的状态的视觉显示。 在本发明的另一个实施例中，使用软件峰值寻找算法来提供确定连续半衰期的包络波形。 比较连续半衰期的相对持续时间以提供衰减量的指示。
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公开(公告)号：US4490806A
公开(公告)日：1984-12-25
申请号：US385115
申请日：1982-06-04
CPC分类号： H01J49/0036 , G01R13/06 , G01R13/32
摘要： A system for high speed acquisition and storage of data from transient electrical signal waveforms sampled in time at a multiplicity of points, and where it is desired to collect and store data in real time in a mass storage unit, but where the data rate is in excess of the apparent rate at which data can be transferred to mass storage. The overall system employs two levels of data reduction, the first being digital integration (summation) and the second being data processing. In the digital summation section memory read and write cycles overlap for higher speed. In one embodiment, a charge-coupled device is employed as an input element to reduce the data rate prior to subsequent digital processing. The system is capable of recording all the intensities of all transients continuously without loss of data significance.
摘要翻译： 一种用于高速采集和存储来自在多个点上及时采样的瞬时电信号波形的数据的系统，并且其中期望在大容量存储单元中实时收集和存储数据，但是数据速率在 数据可以转移到大容量存储的表观速率过多。 整个系统采用两级数据缩减，首先是数字积分（summation），第二种是数据处理。 在数字求和部分，存储器的读写周期重叠较快。 在一个实施例中，电荷耦合器件被用作输入元件，以在随后的数字处理之前降低数据速率。 该系统能够连续记录所有瞬变的所有强度，而不会损失数据的意义。
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