公开(公告)号：US10226275B2

公开(公告)日：2019-03-12

申请号：US12932370

申请日：2011-02-24

Applicant: Paul Q Escudero ,  John T To ,  Christopher J Danek ,  Uriel H Chee ,  August C Pombo ,  Torrey Smith ,  Brenda Hann

Inventor： Paul Q Escudero ,  John T To ,  Christopher J Danek ,  Uriel H Chee ,  August C Pombo ,  Torrey Smith ,  Brenda Hann

IPC: A61B17/32 ,  A61B17/22 ,  A61B17/3207 ,  A61M25/01 ,  A61B17/00 ,  A61B17/29

Abstract: Devices, systems, and methods are employed to restore patency to arterial lesions, e.g., by debulking restenosis in a blood vessel or within a stent or coil.

公开(公告)号：US09610095B2

公开(公告)日：2017-04-04

申请号：US12582638

申请日：2009-10-20

Applicant: John T. To

Inventor： John T. To

IPC: A61B17/34 ,  A61B10/06 ,  A61B1/313 ,  A61B5/00 ,  A61B8/12 ,  A61B17/02 ,  A61B17/00 ,  A61B17/32 ,  A61B90/00

CPC classification number: A61B17/3417 ,  A61B1/3135 ,  A61B5/0084 ,  A61B8/12 ,  A61B10/06 ,  A61B17/0218 ,  A61B90/361 ,  A61B2017/00261 ,  A61B2017/003 ,  A61B2017/00907 ,  A61B2017/320064 ,  A61B2017/3419

Abstract: Retractor cannula systems may be used for accessing and visualizing the spine and related methods of treatment, including a forward-looking retractor cannula system for creating a working space and the retractor cannula system having atraumatic dissection capability to allow visualization in spine. The devices and methods described may be used, for example, to perform annulus repair, herniated disc excision, and denervation of neurological tissue; to dispense pharmacological agents and/or cell or tissue therapy agents; to diagnose disc degeneration and bony degeneration, spinal stenosis, and nucleus decompression, and to perform disc augmentation.

公开(公告)号：US09492192B2

公开(公告)日：2016-11-15

申请号：US12215854

申请日：2008-06-30

Applicant: John T To ,  Christopher James Danek ,  Paul Quentin Escudero ,  Uriel Hiram Chee ,  August Christopher Pombo ,  Torrey Smith ,  Brenda Hann

Inventor： John T To ,  Christopher James Danek ,  Paul Quentin Escudero ,  Uriel Hiram Chee ,  August Christopher Pombo ,  Torrey Smith ,  Brenda Hann

IPC: A61B17/3207 ,  A61B17/00 ,  A61B17/22

CPC classification number: A61B17/320758 ,  A61B2017/003 ,  A61B2017/00685 ,  A61B2017/22039 ,  A61B2017/22044 ,  A61B2017/22068 ,  A61B2017/22094 ,  A61B2017/320716 ,  A61B2017/320766 ,  A61B2017/320775

Abstract: The devices and methods generally relate to treatment of occluded body lumens. In particular, the present devices and method relate to removal of the occluding material from the blood vessels as well as other body lumens.

公开(公告)号：US09049986B2

公开(公告)日：2015-06-09

申请号：US13237866

申请日：2011-09-20

Applicant: Lex P. Jansen ,  John T. To ,  John W. Davis ,  Stewart M. Kume ,  Wendy Twardzik

Inventor： Lex P. Jansen ,  John T. To ,  John W. Davis ,  Stewart M. Kume ,  Wendy Twardzik

IPC: A61B1/00 ,  A61B1/005 ,  A61B1/313 ,  A61B17/16 ,  A61B17/32 ,  A61B17/3205 ,  A61B17/34 ,  A61B1/015 ,  A61B1/018 ,  A61B17/17 ,  A61B17/22 ,  A61B17/00 ,  A61B19/00

CPC classification number: A61B1/00154 ,  A61B1/005 ,  A61B1/015 ,  A61B1/018 ,  A61B1/3135 ,  A61B17/00234 ,  A61B17/0218 ,  A61B17/1604 ,  A61B17/1637 ,  A61B17/1644 ,  A61B17/1671 ,  A61B17/1757 ,  A61B17/22031 ,  A61B17/320016 ,  A61B17/32053 ,  A61B17/3415 ,  A61B17/3423 ,  A61B2017/00261 ,  A61B2017/00398 ,  A61B2017/0262 ,  A61B2090/3937

Abstract: Systems and methods for treating spinal stenosis include endoscopic access devices and bone removal devices used to perform a foraminotomy or other bone removal procedures. A bone removal device includes a cannulotome with an endoscopic imaging lumen. Optionally, an endoscope retaining device can be used to facilitate advancement of the endoscope through the cannulotome.

Abstract translation: 用于治疗脊柱狭窄的系统和方法包括用于进行椎间孔切开术或其他骨移除手术的内窥镜检查装置和骨移除装置。 骨去除装置包括具有内窥镜成像内腔的插管切除器。 可选地，内窥镜保持装置可以用于促进内窥镜通过管腔切除器的前进。

公开(公告)号：US08808320B2

公开(公告)日：2014-08-19

申请号：US12825251

申请日：2010-06-28

Applicant: David Batten ,  John T. To ,  Hiep Nguyen

Inventor： David Batten ,  John T. To ,  Hiep Nguyen

IPC: A61B17/32

CPC classification number: A61B17/32002 ,  A61B17/1615 ,  A61B17/1617 ,  A61B17/1671 ,  A61B2017/320064

Abstract: Disclosed herein are tissue-removal devices and methods for treating spinal diseases using such devices. The tissue-removal devices may comprise a cable and/or extendable elements with a retracted and a deployed configuration. The cable and/or extendable elements may be distally supported and restrained by a support element such that the support element may be pushed transversely away when the extendable element is distally extended into its deployed configuration. An annular cutting element may be provided about the distal end of the extendable element or the support element. Various configurations of the extendable and support elements are described herein, as well as methods of using tissue-removal devices with extendable and support elements coupled by an annular cutting element for treating spinal diseases.

Abstract translation: 本文公开了使用这种装置治疗脊柱疾病的组织去除装置和方法。 组织去除装置可以包括具有缩回和展开构造的电缆和/或可延伸元件。 电缆和/或可延伸元件可以由支撑元件远端地支撑和限制，使得当可延伸元件向远侧延伸到其展开构型时，支撑元件可被横向推开。 可以围绕可延伸元件的远端或支撑元件设置环形切割元件。 本文描述了可延伸和支撑元件的各种构造，以及使用具有通过环形切割元件联接以治疗脊柱疾病的可延伸和支撑元件的组织去除装置的方法。

公开(公告)号：US20130282006A1

公开(公告)日：2013-10-24

申请号：US13917930

申请日：2013-06-14

Applicant: Simon W. H. THOMAS ,  Peter S. EDELSTEIN ,  John T. TO ,  Benjamin T. NORDELL ,  Stuart D. EDWARDS

Inventor： Simon W. H. THOMAS ,  Peter S. EDELSTEIN ,  John T. TO ,  Benjamin T. NORDELL ,  Stuart D. EDWARDS

IPC: A61B18/00

CPC classification number: A61B18/00 ,  A61B17/0625 ,  A61B18/02 ,  A61B18/14 ,  A61B18/1477 ,  A61B18/1485 ,  A61B2017/00805 ,  A61B2017/00867 ,  A61B2018/00029 ,  A61B2018/00035 ,  A61B2018/00178 ,  A61B2018/00285 ,  A61B2018/00523 ,  A61B2018/00553 ,  A61B2018/00559 ,  A61B2018/00916 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2218/007 ,  A61N1/06 ,  A61N7/022 ,  C08L2201/12

Abstract: Apparatus and methods are provided for treating female urinary incontinence by applying a form of energy to tissue in the vicinity of the urethra and/or bladder outlet to change tissue compliance without substantially narrowing the urethral and/or bladder outlet lumen. The apparatus comprises an elongated shaft having a means for treating urethral tissue and an expandable member deployable distal of the means for treating. The expandable member is configured to be anchored against the bladder outlet to dispose the means for treating at a desired treatment site in the urethra using only tactile feedback. The means for treating may include a needleless RF electrode, an ultrasound transducer, or a cryogenic probe configured to be advanced through a hollow needle, each of which are designed to reduce or eliminate symptoms associated with urinary incontinence.

Abstract translation: 提供了用于通过向尿道和/或膀胱出口附近的组织施加能量来改变组织依从性而不使尿道和/或膀胱出口腔基本上变窄来治疗女性尿失禁的装置和方法。 该装置包括细长轴，其具有用于治疗尿道组织的装置和可展开装置的可扩展构件。 可膨胀构件被构造成锚固在膀胱出口上，以仅使用触觉反馈来将用于治疗的装置设置在尿道中的期望的治疗部位。 用于治疗的装置可以包括无针RF电极，超声换能器或构造成通过中空针前进的低温探针，每个都被设计为减少或消除与尿失禁相关的症状。

公开(公告)号：US20120197247A1

公开(公告)日：2012-08-02

申请号：US13443713

申请日：2012-04-10

Applicant: Simon W. H. Thomas ,  Peter S. Edelstein ,  John T. To ,  Benjamin T. Nordell ,  Stuart D. Edwards

Inventor： Simon W. H. Thomas ,  Peter S. Edelstein ,  John T. To ,  Benjamin T. Nordell ,  Stuart D. Edwards

IPC: A61B18/18

CPC classification number: A61B18/00 ,  A61B17/0625 ,  A61B18/02 ,  A61B18/14 ,  A61B18/1477 ,  A61B18/1485 ,  A61B2017/00805 ,  A61B2017/00867 ,  A61B2018/00029 ,  A61B2018/00035 ,  A61B2018/00178 ,  A61B2018/00285 ,  A61B2018/00523 ,  A61B2018/00553 ,  A61B2018/00559 ,  A61B2018/00916 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2218/007 ,  A61N1/06 ,  A61N7/022 ,  C08L2201/12

Abstract: Apparatus and methods are provided for treating female urinary incontinence by applying a form of energy to tissue in the vicinity of the urethra and/or bladder outlet to change tissue compliance without substantially narrowing the urethral and/or bladder outlet lumen. The apparatus comprises an elongated shaft having a means for treating urethral tissue and an expandable member deployable distal of the means for treating. The expandable member is configured to be anchored against the bladder outlet to dispose the means for treating at a desired treatment site in the urethra using only tactile feedback. The means for treating may include a needleless RF electrode, an ultrasound transducer, or a cryogenic probe configured to be advanced through a hollow needle, each of which are designed to reduce or eliminate symptoms associated with urinary incontinence.

Abstract translation: 提供了用于通过向尿道和/或膀胱出口附近的组织施加能量来改变组织依从性而不使尿道和/或膀胱出口腔基本上变窄来治疗女性尿失禁的装置和方法。 该装置包括细长轴，其具有用于治疗尿道组织的装置和可展开装置的可扩展构件。 可膨胀构件被构造成锚固在膀胱出口上，以仅使用触觉反馈来将用于治疗的装置设置在尿道中的期望的治疗部位。 用于治疗的装置可以包括无针RF电极，超声换能器或构造成通过中空针前进的低温探针，每个都被设计为减少或消除与尿失禁相关的症状。

公开(公告)号：US20120071714A1

公开(公告)日：2012-03-22

申请号：US13237866

申请日：2011-09-20

Applicant: Lex P. JANSEN ,  John T. To ,  John W. Davis ,  Stewart M. Kume ,  Wendy Twardzik

Inventor： Lex P. JANSEN ,  John T. To ,  John W. Davis ,  Stewart M. Kume ,  Wendy Twardzik

IPC: A61B1/00

CPC classification number: A61B1/00154 ,  A61B1/005 ,  A61B1/015 ,  A61B1/018 ,  A61B1/3135 ,  A61B17/00234 ,  A61B17/0218 ,  A61B17/1604 ,  A61B17/1637 ,  A61B17/1644 ,  A61B17/1671 ,  A61B17/1757 ,  A61B17/22031 ,  A61B17/320016 ,  A61B17/32053 ,  A61B17/3415 ,  A61B17/3423 ,  A61B2017/00261 ,  A61B2017/00398 ,  A61B2017/0262 ,  A61B2090/3937

Abstract: Systems and methods for treating spinal stenosis include endoscopic access devices and bone removal devices used to perform a foraminotomy or other bone removal procedures. A bone removal device includes a cannulotome with an endoscopic imaging lumen. Optionally, an endoscope retaining device can be used to facilitate advancement of the endoscope through the cannulotome.

公开(公告)号：US20120016260A1

公开(公告)日：2012-01-19

申请号：US13245815

申请日：2011-09-26

Applicant: John T. To

Inventor： John T. To

IPC: A61B10/00 ,  A61B1/00

CPC classification number: A61B17/3417 ,  A61B1/3135 ,  A61B5/0084 ,  A61B8/12 ,  A61B10/06 ,  A61B17/0218 ,  A61B90/361 ,  A61B2017/00261 ,  A61B2017/003 ,  A61B2017/00907 ,  A61B2017/320064 ,  A61B2017/3419

Abstract: Retractor cannula systems may be used for accessing and visualizing the spine and related methods of treatment, including a forward-looking retractor cannula system for creating a working space and the retractor cannula system having atraumatic dissection capability to allow visualization in spine. The devices and methods described may be used, for example, to perform annulus repair, herniated disc excision, and denervation of neurological tissue; to dispense pharmacological agents and/or cell or tissue therapy agents; to diagnose disc degeneration and bony degeneration, spinal stenosis, and nucleus decompression, and to perform disc augmentation.

Abstract translation: 牵引器套管系统可以用于访问和可视化脊柱和相关的治疗方法，包括用于创建工作空间的前瞻性牵开器插管系统和具有无创解剖能力以允许在脊柱中可视化的牵开器套管系统。 所描述的装置和方法可以用于例如执行环带修复，突出的椎间盘切除和神经组织的去神经支配; 分配药理学试剂和/或细胞或组织治疗剂; 诊断椎间盘退变和骨变性，脊柱狭窄和细胞核减压，并进行椎间盘增大。

公开(公告)号：US20110152907A1

公开(公告)日：2011-06-23

申请号：US12932371

申请日：2011-02-24

Applicant: Paul Quentin Escudero ,  John T. To ,  Christopher James Danek ,  Uriel Hiran Chee ,  August Christopher Pombo ,  Torrey Smith ,  Brenda Hann

Inventor： Paul Quentin Escudero ,  John T. To ,  Christopher James Danek ,  Uriel Hiran Chee ,  August Christopher Pombo ,  Torrey Smith ,  Brenda Hann

IPC: A61B17/22

CPC classification number: A61B17/3207 ,  A61B17/320758 ,  A61B2017/003 ,  A61B2017/00309 ,  A61B2017/00685 ,  A61B2017/22039 ,  A61B2017/22044 ,  A61B2017/22068 ,  A61B2017/22094 ,  A61B2017/2929 ,  A61B2017/320032 ,  A61B2017/320775 ,  A61M25/0138

Abstract: Devices, systems, and methods are employed to perform an atherectomy in an identified region to restore patency to arterial lesions. A bioactive material is introduced into the identified region before, after or during performing the atherectomy. The bioactive material can be introduced, e.g., on a balloon coated with the bioactive material, which is expanded in contact with the identified region to deliver the bioactive material. The bioactive material can be, e.g., at least one of a restenosis-inhibiting agent, a thrombus-inhibiting agent, and an anti-inflammatory agent.

Abstract translation: 使用装置，系统和方法在识别的区域中进行粥样斑块切除术以恢复对动脉损伤的通畅。 在进行粥样斑块切除术之前，之后或期间将生物活性物质引入识别的区域。 生物活性材料可以例如引入涂覆有生物活性材料的球囊上，所述球囊与所识别的区域接触扩张以递送生物活性物质。 生物活性物质可以是例如再狭窄抑制剂，血栓抑制剂和抗炎剂中的至少一种。