公开(公告)号：US20090320925A1

公开(公告)日：2009-12-31

申请号：US12146264

申请日：2008-06-25

申请人： Jon A. Nichols

发明人： Jon A. Nichols

IPC分类号： F16K11/02

CPC分类号： F16K11/0743 ,  F16K3/08 ,  Y10T137/0318 ,  Y10T137/86863

摘要： A shear valve assembly that includes a stator element having a body, a stator face and at least a first stator passage and a second stator passage extending through the stator body. The first passage and the second passage terminate at the stator face at a respective first stator port and a respective second stator port. The valve further includes a rotor element that defines a rotor face configured for fluid-tight contact against the stator face at a rotor/stator interface. The rotor face defines a first rotor port and a spaced second rotor port, and a rotor body thereof defines a first subterranean passage extending fully beneath the plane of the rotor face. One end of the subterranean passage terminates at the first rotor port at the rotor face surface, while an opposite end thereof terminates at the second rotor port at the rotor face. The rotor face and the stator face is rotatable about a rotation axis relative one another between a first position and a second position. In the first position, the first subterranean passage fluidly couples the first stator port and the second stator port with the first rotor port and the second rotor port, enabling fluid flow between the first stator passage, through the first subterranean passage, and the second stator passage. In the second position, the first subterranean passage is fluidly decoupled from at least one of the first stator port and the second stator port, preventing flow therethrough.

摘要翻译： 一种剪切阀组件，其包括具有本体的定子元件，定子面和至少第一定子通道以及延伸穿过定子体的第二定子通道。 第一通道和第二通道在相应的第一定子口和相应的第二定子口处在定子面处终止。 阀还包括转子元件，该转子元件限定了在转子/定子界面处被配置为与定子面流体紧密接触的转子面。 转子面限定第一转子端口和间隔开的第二转子端口，其转子本体限定了完全延伸在转子面平面下方的第一地下通道。 地下通道的一端在转子表面的第一转子端处终止，而其相对端终止在转子面处的第二转子端口处。 转子面和定子面可以在第一位置和第二位置之间相对于旋转轴线相对旋转。 在第一位置，第一地下通道将第一定子口和第二定子口与第一转子端口和第二转子端口流体耦合，使得第一定子通道之间的流体能够通过第一地下通道和第二定子 通道。 在第二位置，第一地下通道与第一定子口和第二定子口中的至少一个流体地分离，从而防止流过其中。

公开(公告)号：US06382035B1

公开(公告)日：2002-05-07

申请号：US09824865

申请日：2001-04-02

申请人： Jon A. Nichols

发明人： Jon A. Nichols

IPC分类号： G01N100

CPC分类号： G01N35/1097 ,  G01N30/16 ,  G01N30/20 ,  G01N30/24

摘要： A multi-function valve apparatus for use with a Probe-In-Loop (PIL) architecture sample injection assembly which enables both Partial-Fill and Complete-Fill injections. The rotor element is rotatable about a rotation axis relative the stator between: a Load Position, an Overfill Position, and an Injection Position. In the Load Position, a first bridge channel fluidly couples a metering syringe to the sample loop assembly enabling the probe to aspirate one of a discrete volume of sample into the probe, during a Partial-Fill Mode, and a second volume of sample into the probe, during a Complete-Fill Mode. In the Overfill Position, in the Complete-Fill Mode, a second bridge channel fluidly couples a downstream loop portion to a waste port, and the first bridge channel fluidly couples the metering syringe to an upstream loop portion of the sample loop assembly. This enables the metering pump to dispense the sample from the probe into the downstream loop portion and out the waste port to completely fill the downstream loop portion and the second bridge channel with a substantially precise known volume. In the Injection Position, the second bridge channel fluidly couples the downstream loop portion to the analyzing device to inject the sample into the analyzing device, in either the Partial-Fill Mode or and the Complete-Fill Mode.

摘要翻译： 一种多功能阀门装置，与Probe-In-Loop（PIL）结构样品注射组件一起使用，可实现部分填充和完全填充注射。 转子元件可绕相对于定子的旋转轴线在：负载位置，过度填充位置和喷射位置之间旋转。 在负载位置，第一桥接通道将计量注射器流体地耦合到样品环组件，使得探针能够在部分填充模式期间将离散体积的样品中的一个抽吸到探针中，并将第二体积的样品吸入 探针，在完全填充模式下。 在填充位置中，在完全填充模式中，第二桥接通道将下游环路部分流体地耦合到废物端口，并且第一桥接通道将计量注射器流体地耦合到样品环组件的上游环路部分。 这使得计量泵能够将样品从探针分配到下游环路部分中并从出口端口排出，以完全填充具有基本精确的已知体积的下游环路部分和第二桥接通道。 在注射位置，第二桥接通道将下游环路部分流体地耦合到分析装置，以将样品以部分填充模式或完全填充模式注入分析装置。

公开(公告)号：US6012488A

公开(公告)日：2000-01-11

申请号：US179348

申请日：1998-09-17

申请人： Jon A. Nichols

发明人： Jon A. Nichols

IPC分类号： F16K11/074

CPC分类号： F16K11/0743 ,  Y10T137/86501 ,  Y10T137/86533

摘要： A valve that receives sample and solvent streams, and delivers slugs of different fluid samples separated by slugs of the solvent, to a detector. The valve includes a stator (140) having a central hole (40) and a circle of sample holes (51-54) and solvent holes (91-94). The valve also includes a rotor (150) with a first groove (162) that connects one of the sample or solvent holes to the central hole to flow to the detector. The first groove is wide enough and the space between adjacent supply holes is small enough, that as the first groove moves from one hole of the circle to the next, the groove becomes partially open to the next hole before it leaves the last hole to minimize the sudden increase in pressure along the flow to the detector. The stator face has a waste recess (144) and the rotor has one or more waste grooves (171-177) that extend between the first circle and the waste recess, so when a sample from a sample hole is not flowing as a slug toward the detector, the sample instead flows to the waste recess for disposal, to minimize the sudden increase in pressure at the sample holes.

摘要翻译： 接收样品和溶剂流并将不同流体样品的块塞从溶剂中分离出来的阀到检测器。 该阀包括具有中心孔（40）和一个样品孔（51-54）和溶剂孔（91-94）的圆的定子（140）。 阀还包括具有第一凹槽（162）的转子（150），其将样品或溶剂孔中的一个连接到中心孔以流向检测器。 第一沟槽足够宽，相邻供应孔之间的空间足够小，当第一槽从圆的一个孔移动到下一个孔时，槽在其离开最后一个孔之前对下一个孔部分地打开以最小化 沿着流向检测器的压力突然增加。 定子面具有废物凹部（144），转子具有一个或多个在第一个圆周和废物凹槽之间延伸的废物槽（171-177），因此当来自样品孔的样品不会以块状方式流动时 检测器，样品代替流入废物处理槽，以尽可能减少样品孔的压力突然增加。

公开(公告)号：US07575723B2

公开(公告)日：2009-08-18

申请号：US11025546

申请日：2004-12-28

申请人： Jon A. Nichols ,  Marc D. Foster

发明人： Jon A. Nichols ,  Marc D. Foster

IPC分类号： B10L11/00

CPC分类号： H01J49/04 ,  Y10T436/2575

摘要： While a large primary stream (24) of analytes flow from a chromatographic column (20) to containers of a receiver (108), small samples of the analytes are diverted for flow to a mass spectrometer (54) for analysis, by use of a transfer module (102). The transfer module includes a stator (110) and a rotor or shuttle (114). The shuttle has an aliquot passage (120) that initially lies in a first position where the primary stream flows through it so the aliquot passage receives a small sample. The shuttle then moves to a second position where the aliquot passage (at 122) is aligned with a pump (134) that pumps fluid out of the aliquot passage to the mass spectrometer.

摘要翻译： 尽管分析物的大的主要流（24）从色谱柱（20）流向接收器（108）的容器，但是将分析物的小样品转移到质谱仪（54）以进行分析，通过使用 传送模块（102）。 转移模块包括定子（110）和转子或梭（114）。 穿梭具有初始位于第一位置的等分通道（120），其中主流体流过它，使得等分通道接收小样品。 然后梭子移动到第二位置，其中等分试样通道（在122处）与泵（134）对准，泵（134）将流体从等分试样通道推出到质谱仪。

公开(公告)号：US07201185B2

公开(公告)日：2007-04-10

申请号：US11057395

申请日：2005-02-11

申请人： Carl H. Poppe ,  Carl M. Servin ,  Jon A. Nichols ,  Michael R. Straka

发明人： Carl H. Poppe ,  Carl M. Servin ,  Jon A. Nichols ,  Michael R. Straka

IPC分类号： F16K31/02

CPC分类号： F16K31/04 ,  Y10T137/5109 ,  Y10T137/8242 ,  Y10T137/87772

摘要： A multi-position micro-fluidic valve system that includes an actuator assembly with a housing and a drive shaft rotatably disposed in the housing for rotational displacement about a drive axis thereof. One end of the drive shaft is configured to couple to a drive motor for selective rotation of the drive shaft about the drive axis. One of at least two different multi-position fluid valve devices can be removably mated to the actuator assembly. Each valve device is configured for rotational movement of a corresponding valve shaft about a valve rotational axis thereof between a plurality of discrete fluid distribution positions. A coupling device selectively and removably mounts the valve shaft of the respective valve device to the drive shaft of the actuator assembly. This enables selective positioning of the multi-position fluid valve device at a discrete one of the plurality for discrete distribution positions.

摘要翻译： 一种多位置微流体阀系统，其包括具有壳体的致动器组件和可旋转地设置在壳体中的驱动轴，用于围绕其驱动轴线旋转移动。 驱动轴的一端构造成联接到驱动电动机，用于围绕驱动轴线选择性地旋转驱动轴。 至少两个不同的多位置流体阀装置中的一个可以可拆卸地配合到致动器组件。 每个阀装置构造成用于在多个离散流体分配位置之间绕其阀旋转轴线旋转相应阀轴的旋转运动。 联接装置选择性地并且可移除地将各个阀装置的阀轴安装到致动器组件的驱动轴上。 这使得多位置流体阀装置能够在离散分配位置的多个离散的位置之间进行选择性定位。

公开(公告)号：US06890489B2

公开(公告)日：2005-05-10

申请号：US09835198

申请日：2001-04-13

申请人： Jon A. Nichols ,  Marc D. Foster

发明人： Jon A. Nichols ,  Marc D. Foster

IPC分类号： H01J49/04 ,  B01L11/01 ,  G01N1/10

CPC分类号： H01J49/04 ,  Y10T436/2575

摘要： While a large primary stream (24) of analytes flow from a chromatographic column (20) to containers of a receiver (108), small samples of the analytes are diverted for flow to a mass spectrometer (54) for analysis, by use of a transfer module (102). The transfer module includes a stator (110) and a rotor or shuttle (114). The shuttle has an aliquot passage (120) that initially lies in a first position where the primary stream flows through it so the aliquot passage receives a small sample. The shuttle then moves to a second position where the aliquot passage (at 122) is aligned with a pump (134) that pumps fluid out of the aliquot passage to the mass spectrometer.

公开(公告)号：US06672336B2

公开(公告)日：2004-01-06

申请号：US09998529

申请日：2001-11-28

申请人： Jon A. Nichols

发明人： Jon A. Nichols

IPC分类号： F16K11074

CPC分类号： F16K11/074 ,  Y10T137/86501 ,  Y10T137/86863

摘要： A multi-function, random access, dual, three-way valve for use with fluid switching and the like is provided, whereby a first fluid flow to the valve is selectively placed in fluid communication with a first or a second outlet passage from the valve for selectively transferring the first fluid flow and a second fluid flow to the valve is, independent of the flow path of the first fluid, selectively placed in fluid communication with a third or a fourth outlet from the valve for simultaneously transferring the second fluid flow. A rotor element rotatably movable relative to a stationary stator element to at least four discrete angular positions actuates to multi-function switching capabilities of the valve when the rotor element is selectively placed in one of the at least four discrete positions. The valve directs the first fluid flow to one of two alternate outlet passages and, simultaneously and independently, directs the second fluid flow to one of at least two different outlet passages.

摘要翻译： 提供了一种用于流体切换等的多功能，随机存取，双向三通阀，由此，向阀的第一流体流选择性地与来自阀的第一或第二出口通道流体连通 用于选择性地将第一流体流转移到第二流体流，而与第一流体的流动路径无关，其选择性地与阀的第三或第四出口流体连通，以同时传送第二流体流。 当转子元件选择性地放置在至少四个离散位置中的一个位置时，可相对于固定定子元件可旋转地移动到至少四个离散角位置的转子元件致动阀的多功能切换能力。 阀将第一流体流引导到两个备选出口通道中的一个，并且同时且独立地将第二流体流引导至至少两个不同的出口通道中的一个。

公开(公告)号：US06453946B2

公开(公告)日：2002-09-24

申请号：US09800320

申请日：2001-03-06

申请人： Jon A. Nichols ,  Burney L. Baron

发明人： Jon A. Nichols ,  Burney L. Baron

IPC分类号： F16K11074

CPC分类号： F16K11/074 ,  F16K25/005 ,  G01N30/20 ,  G01N2030/201 ,  G01N2030/202 ,  Y10T137/86533

摘要： A rotary fluid switching valve has facewise adjacent rotor and stator faces of materials that result in an exceptionally long lifetime. One face is of a fluorocarbon-containing polymer, while the other face is Tungsten Carbide/Carbon (WC/C). The WC/C coating is preferably on a metal stator which has machined ports to accept tubing fittings that connect to stator passages that extend to the interface of stator and rotor.

摘要翻译： 旋转流体切换阀具有面向相邻的转子和材料的定子面，导致特别长的使用寿命。 一面是含碳氟化合物的聚合物，另一面是碳化钨/碳（WC / C）。 WC / C涂层优选在金属定子上，该金属定子具有加工端口以接纳连接到延伸到定子和转子的界面的定子通道的管接头。