Real time microarrays
    2.
    发明授权
    Real time microarrays 有权
    实时微阵列

    公开(公告)号:US09133504B2

    公开(公告)日:2015-09-15

    申请号:US11758621

    申请日:2007-06-05

    IPC分类号: C12Q1/68

    摘要: This invention provides methods and systems for measuring the binding of analytes in solution to probes bound to surfaces in real-time. The method involves contacting a fluid volume having a plurality of different analytes with a solid substrate having a plurality of different probes. The probes are capable of specifically binding to the analytes. The method also involves measuring signals at multiple time points while the fluid volume is in contact with the substrate. The signals measured at multiple time points can be correlated with the amount of binding of the analytes with the probes. The method eliminates the need to wash the probes before measuring the binding characteristics.

    摘要翻译: 本发明提供了用于测量溶液中分析物与实际上与表面结合的探针的结合的方法和系统。 该方法包括将具有多个不同分析物的流体体积与具有多个不同探针的固体基质接触。 探针能够特异性地结合分析物。 该方法还涉及在流体体积与基底接触时在多个时间点测量信号。 在多个时间点测量的信号可以与分析物与探针的结合量相关。 该方法消除了在测量结合特性之前洗涤探针的需要。