摘要:
In a construction machine of a small rotational inertia such as an intrawidth swing machine or a small-sized excavator, a rotative operability varies depending on the posture of a working attachment, and in a reduced state of reach, a change in rotating force is oversensitive to the operation of a working lever, so operation is difficult. To cope with this point, means for detecting the operation of a rotating direction control valve is provided, and an outlet of a center bypassing oil path in the rotating direction control valve and an oil tank are brought into communication with each other through a cut-off valve used for controlling the bleed-off thereof. Further, a pilot port of the cut-off valve and a source of a pilot oil pressure are brought into communication with each other through an electromagnetic proportional pressure reducing valve, and an operation command signal is issued from a controller to the electromagnetic proportional pressure control valve to control the acceleration of rotation and the maximum rotating speed.
摘要:
A control unit for controlling the hydraulic system of a construction machine, such as a hydraulic shovel, having a structure capable of being simply and quickly changed from one setup for another setup suitable for a desired mode of control operation. The control unit comprises a control lever pivotally supported for movement in longitudinal and transverse directions, and first and second link rods for transmitting the operating force of the control lever to first and second hydraulic control valves when the control lever is shifted in the longitudinal and transverse directions, respectively. An operating force transmitting member is put on the control lever so as to be rotatable about the axis of the control lever, and a locking member is mounted on the control lever so as to be slidable along the axis of the control lever and so as to be unable to rotate relative to the control lever. In changing the setup of the control unit, the locking member is disengaged from the operating power transmitting member, the operating power transmitting member is turned through an angle of 90.degree., and then the locking member is brought into engagement with the operating force transmitting member to lock the operating force transmitting lever in place relative to the control lever.
摘要:
Compounds useful as preventive and therapeutic agents for bone and cartilage diseases; and drug compositions containing the same. The compounds are polyhydroxyphenol derivatives of general formula (I) and quinione analogues derived therefrom (wherein R1 is alkyl, optionally substituted benzyl or optionally substituted aryl; R2 is hydrogen, alkyl, alkenyl or optionally substituted benzyl; R3 is hydrogen, alkyl, alkenyl, optionally substituted benzyl, hydroxyl, alkoxy, alkenyloxy or optionally substituted benzyloxy; R4 is hydrogen, alkyl, alkenyl, optionally substituted benzyl or hydroxyl; and R5 and R6 are each independently hydrogen, alkyl, alkenyl or optionally substituted benzyl). The polyhydroxyphenol derivatives and the quinone analogues exhibit a potent inhibitory activity against bone resorption and are useful as preventive and therapeutic agents for bone and cartilage diseases.
摘要翻译:用作骨和软骨疾病的预防和治疗剂的化合物; 和含有它们的药物组合物。 化合物是通式(I)的多羟基苯酚衍生物和由其衍生的醌基类似物(其中R1是烷基,任意取代的苄基或任意取代的芳基; R 2是氢,烷基,烯基或任选取代的苄基; R 3是氢,烷基,链烯基, 任选取代的苄基,羟基,烷氧基,烯氧基或任选取代的苄氧基; R 4是氢,烷基,烯基,任选取代的苄基或羟基;且R 5和R 6各自独立地为氢,烷基,烯基或任选取代的苄基。 多羟基苯酚衍生物和醌类似物表现出对骨吸收的有效抑制活性,并且可用作骨和软骨疾病的预防和治疗剂。
摘要:
An isolated protein having the amino terminal sequence of SEQ ID No. 1 and having a molecular weight of about 200 KDa is described. This animal brain-derived protein binds to OSF-1 (HBGF-8), which is a heparin-binding growth factor that has neuronal differentiation-enhancing activity, and a proliferative action on osteoblasts.
摘要:
An industrial robot system comprising a single working machine, and a plurality of robots arranged so as to transfer a work to and from this working machine. The operation of these robots and the working machine is controlled by a single control unit, and the operation of all the robots is controlled in a realtime manner in synchronism with the operation of the working machine, thereby ensuring the smooth operation of the overall system while obviating waiting time of each robot and the working machine without using a conventional mutual interlock system. The control unit is set so that clocks of the robots and the working machine and the system clock are counted up in the same cycle time, simultaneously therewith the original point clock value of the robot or the working machine located on the most upstream side of the system is set as the original clock value of the system, and each of the robots and the working machine is operated as the count of the system clock reaches the original clock value of the robot on the working machine.
摘要:
A method for coating steel structures in water which comprisescoating as a first layer an underwater-curable composition comprising(1) a two-pack resin blend system comprising(a) a blend system comprising an epoxy-based resin, and(b) a blend system comprising an underwater-curable curing agent capable of hardening the epoxy-based resin blend system, and(2) from 5 to 75% by weight, based on the total weight of the underwater-curable composition, of a metal powder having an ionization tendency greater than that of iron,on the steel structures, andcoating an underwater-curable composition comprising the two-pack resin blend system and a coloring pigment on the first layer as a second layer.
摘要:
A detailed linkage analysis of the Ehd1 region was performed with a large segregating population, essential for map-based cloning. As a result, the Ehd1 gene promoting rice heading (flowering) was successfully isolated. Rice heading time was also found to be altered upon introduction of this gene. Based on these facts, the newly isolated and identified Ehd1 gene is expected to be useful in promoting plant flowering.
摘要:
A detailed linkage analysis of the Ehd1 region was performed with a large segregating population, essential for map-based cloning. As a result, the Ehd1 gene promoting rice heading (flowering) was successfully isolated. Rice heading time was also found to be altered upon introduction of this gene. Based on these facts, the newly isolated and identified Ehd1 gene is expected to be useful in promoting plant flowering.
摘要:
Pharmaceutical composition for preventing or treating bone fracture comprising as an active ingredient a platelet factor 4.The present composition can promote differentiation of osteoblasts so that they are effective for prophylaxis and treatment of such diseases requiring bone differentiation and proliferation as bone fracture and the like.
摘要:
The invention is directed to purified and isolated concanavalin A-binding proteins from chondrocytes that are not present in dedifferentiated cells from chondrocytes. The invention is also directed to a purified and isolated chondrocyte membrane protein, (CMP), which is a concanavalin A-binding protein, with a molecular weight of about 76 kD in SDS-PAGE. After treatment with endoglycosidase, CMP has an apparent molecular weight of about 67 kD. The N-terminal amino acid sequence and several internal amino acid sequences are given for CMP. These proteins can be used in assays, methods, or treatments involving differentiation of chondrocytes and the control of cartilaginous osteogenesis.