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14 条记录 (耗时 0.027 秒)

    Industrial robot system
    1.
    发明授权
    Industrial robot system 失效
    工业机器人系统

    公开(公告)号：US5084826A

    公开(公告)日：1992-01-28

    申请号：US557074

    申请日：1990-07-25

    申请人： Kazuo Hariki ,  Tatsuya Koizumi ,  Kazuya Ishiguro ,  Kiyoshi Kanitani ,  Masaki Togitani ,  Kazuyuki Doi ,  Shin-ichi Izumisawa

    发明人： Kazuo Hariki ,  Tatsuya Koizumi ,  Kazuya Ishiguro ,  Kiyoshi Kanitani ,  Masaki Togitani ,  Kazuyuki Doi ,  Shin-ichi Izumisawa

    IPC分类号： B25J19/06 ,  B25J9/18 ,  G05B19/18 ,  G05B19/4155 ,  G05B19/418 ,  G05B19/42

    CPC分类号： G05B19/41815 ,  Y02P90/08

    摘要： An industrial robot system comprising a single working machine, and a plurality of robots arranged so as to transfer a work to and from this working machine. The operation of these robots and the working machine is controlled by a single control unit, and the operation of all the robots is controlled in a realtime manner in synchronism with the operation of the working machine, thereby ensuring the smooth operation of the overall system while obviating waiting time of each robot and the working machine without using a conventional mutual interlock system. The control unit is set so that clocks of the robots and the working machine and the system clock are counted up in the same cycle time, simultaneously therewith the original point clock value of the robot or the working machine located on the most upstream side of the system is set as the original clock value of the system, and each of the robots and the working machine is operated as the count of the system clock reaches the original clock value of the robot on the working machine.

    摘要翻译： 一种工业机器人系统，包括单个工作机器和多个机器人，其布置成将工件传送到该工作机器和从该工作机器传送工件。 这些机器人和作业机器的操作由单个控制单元控制，并且与作业机器的操作同步地实时地控制所有机器人的操作，从而确保整个系统的平稳运行，同时 无需使用传统的互锁系统，无需每台机器人和作业机器的等待时间。 控制单元被设置为使得机器人，工作机器和系统时钟的时钟在相同的周期时间内被计数，同时机器人或位于最上游侧的工作机器的原点时钟值 系统设置为系统的原始时钟值，并且每个机器人和工作机器都作为系统时钟的计数达到机器人在工作机器上的原始时钟值。

    Polyhydroxyphenol derivatives and preventive and therapeutic agents for bone and cartilage diseases containing the same
    2.
    发明授权
    Polyhydroxyphenol derivatives and preventive and therapeutic agents for bone and cartilage diseases containing the same 失效
    聚羟基苯酚衍生物以及含有其的骨和软骨疾病的预防和治疗剂

    公开(公告)号：US06177474B1

    公开(公告)日：2001-01-23

    申请号：US09180756

    申请日：1998-12-10

    申请人： Kunikazu Sakai ,  Yusuke Satoh ,  Kazuyuki Doi ,  Kazuyuki Kitamura

    发明人： Kunikazu Sakai ,  Yusuke Satoh ,  Kazuyuki Doi ,  Kazuyuki Kitamura

    IPC分类号： A61K3112

    CPC分类号： C07C49/84 ,  C07C45/00 ,  C07C45/46 ,  C07C45/512 ,  C07C45/62 ,  C07C45/68 ,  C07C45/71 ,  C07C49/713 ,  C07C49/743 ,  C07C49/747 ,  C07C49/825 ,  C07C49/83 ,  C07C49/835

    摘要： Compounds useful as preventive and therapeutic agents for bone and cartilage diseases; and drug compositions containing the same. The compounds are polyhydroxyphenol derivatives of general formula (I) and quinione analogues derived therefrom (wherein R1 is alkyl, optionally substituted benzyl or optionally substituted aryl; R2 is hydrogen, alkyl, alkenyl or optionally substituted benzyl; R3 is hydrogen, alkyl, alkenyl, optionally substituted benzyl, hydroxyl, alkoxy, alkenyloxy or optionally substituted benzyloxy; R4 is hydrogen, alkyl, alkenyl, optionally substituted benzyl or hydroxyl; and R5 and R6 are each independently hydrogen, alkyl, alkenyl or optionally substituted benzyl). The polyhydroxyphenol derivatives and the quinone analogues exhibit a potent inhibitory activity against bone resorption and are useful as preventive and therapeutic agents for bone and cartilage diseases.

    摘要翻译： 用作骨和软骨疾病的预防和治疗剂的化合物; 和含有它们的药物组合物。 化合物是通式（I）的多羟基苯酚衍生物和由其衍生的醌基类似物（其中R1是烷基，任意取代的苄基或任意取代的芳基; R 2是氢，烷基，烯基或任选取代的苄基; R 3是氢，烷基，链烯基， 任选取代的苄基，羟基，烷氧基，烯氧基或任选取代的苄氧基; R 4是氢，烷基，烯基，任选取代的苄基或羟基;且R 5和R 6各自独立地为氢，烷基，烯基或任选取代的苄基。 多羟基苯酚衍生物和醌类似物表现出对骨吸收的有效抑制活性，并且可用作骨和软骨疾病的预防和治疗剂。

    Control unit for a construction machine
    4.
    发明授权
    Control unit for a construction machine 失效
    施工机械控制单元

    公开(公告)号：US4981047A

    公开(公告)日：1991-01-01

    申请号：US443472

    申请日：1989-11-30

    申请人： Rinta Denda ,  Masaharu Nishimoto ,  Hidetomo Kasa ,  Kazuyuki Doi

    发明人： Rinta Denda ,  Masaharu Nishimoto ,  Hidetomo Kasa ,  Kazuyuki Doi

    IPC分类号： B62D49/00 ,  B66C13/56 ,  E02F9/20 ,  G05G9/047

    CPC分类号： G05G9/047 ,  E02F9/2004 ,  G05G2009/04718 ,  Y10T137/5196 ,  Y10T137/87072 ,  Y10T403/32262 ,  Y10T403/66 ,  Y10T403/7039 ,  Y10T74/20201 ,  Y10T74/20618 ,  Y10T74/20624

    摘要： A control unit for controlling the hydraulic system of a construction machine, such as a hydraulic shovel, having a structure capable of being simply and quickly changed from one setup for another setup suitable for a desired mode of control operation. The control unit comprises a control lever pivotally supported for movement in longitudinal and transverse directions, and first and second link rods for transmitting the operating force of the control lever to first and second hydraulic control valves when the control lever is shifted in the longitudinal and transverse directions, respectively. An operating force transmitting member is put on the control lever so as to be rotatable about the axis of the control lever, and a locking member is mounted on the control lever so as to be slidable along the axis of the control lever and so as to be unable to rotate relative to the control lever. In changing the setup of the control unit, the locking member is disengaged from the operating power transmitting member, the operating power transmitting member is turned through an angle of 90.degree., and then the locking member is brought into engagement with the operating force transmitting member to lock the operating force transmitting lever in place relative to the control lever.

    Protein having an affinity for a heparin-binding growth factor
    5.
    发明授权
    Protein having an affinity for a heparin-binding growth factor 失效
    对肝素结合生长因子具有亲和力的蛋白质

    公开(公告)号：US5650495A

    公开(公告)日：1997-07-22

    申请号：US549752

    申请日：1996-03-05

    申请人： Michio Kimura ,  Kazuyuki Doi

    发明人： Michio Kimura ,  Kazuyuki Doi

    IPC分类号： A61K38/22 ,  A61P25/00 ,  A61P43/00 ,  C07K1/20 ,  C07K1/22 ,  C07K14/47 ,  C07K14/475 ,  C07K14/51

    CPC分类号： C07K14/475 ,  C07K14/4702 ,  Y10S930/12

    摘要： An isolated protein having the amino terminal sequence of SEQ ID No. 1 and having a molecular weight of about 200 KDa is described. This animal brain-derived protein binds to OSF-1 (HBGF-8), which is a heparin-binding growth factor that has neuronal differentiation-enhancing activity, and a proliferative action on osteoblasts.

    摘要翻译： PCT No.PCT / JP94 / 00832 Sec。 371日期：1996年3月5日 102（e）1996年3月5日PCT PCT 1994年5月25日PCT公布。 公开号WO94 / 28022 日期1994年12月8日描述了具有SEQ ID No.1的氨基末端序列并具有约200KDa分子量的分离的蛋白质。 这种动物脑源性蛋白与OSF-1（HBGF-8）结合，其是具有神经元分化增强活性的肝素结合生长因子和对成骨细胞的增殖作用。

    Medicine for preventing and curing bone fracture
    9.
    发明授权
    Medicine for preventing and curing bone fracture 失效
    用于预防和治愈骨折的药物

    公开(公告)号：US5622935A

    公开(公告)日：1997-04-22

    申请号：US335411

    申请日：1994-11-03

    申请人： Masayoshi Koyama ,  Mikiko Takahashi ,  Kazuyuki Doi

    发明人： Masayoshi Koyama ,  Mikiko Takahashi ,  Kazuyuki Doi

    IPC分类号： A61K47/02 ,  A61K38/00 ,  A61P43/00 ,  C07K14/52

    CPC分类号： C07K14/522 ,  A61K38/00

    摘要： Pharmaceutical composition for preventing or treating bone fracture comprising as an active ingredient a platelet factor 4.The present composition can promote differentiation of osteoblasts so that they are effective for prophylaxis and treatment of such diseases requiring bone differentiation and proliferation as bone fracture and the like.

    摘要翻译： 用于预防或治疗骨折的药物组合物，其包含作为活性成分的血小板因子4.本发明的组合物可以促进成骨细胞分化，使得它们有效预防和治疗需要骨分化和增殖的这种疾病作为骨折等。

    Concanavalin a binding proteins and a 76kD chondrocyte membrane protein (CMP) from chondrocytes and methods for obtaining same
    10.
    发明授权
    Concanavalin a binding proteins and a 76kD chondrocyte membrane protein (CMP) from chondrocytes and methods for obtaining same 失效
    伴刀豆球蛋白结合蛋白和来自软骨细胞的76kD软骨细胞膜蛋白（CMP）及其获得方法

    公开(公告)号：US5607920A

    公开(公告)日：1997-03-04

    申请号：US278617

    申请日：1994-07-21

    申请人： Yukio Kato ,  Haiou Pan ,  Kazuyuki Doi

    发明人： Yukio Kato ,  Haiou Pan ,  Kazuyuki Doi

    IPC分类号： A61K38/00 ,  C07K14/51 ,  C07K1/00 ,  C12N9/00

    CPC分类号： C07K14/51 ,  A61K38/00 ,  Y10S530/84

    摘要： The invention is directed to purified and isolated concanavalin A-binding proteins from chondrocytes that are not present in dedifferentiated cells from chondrocytes. The invention is also directed to a purified and isolated chondrocyte membrane protein, (CMP), which is a concanavalin A-binding protein, with a molecular weight of about 76 kD in SDS-PAGE. After treatment with endoglycosidase, CMP has an apparent molecular weight of about 67 kD. The N-terminal amino acid sequence and several internal amino acid sequences are given for CMP. These proteins can be used in assays, methods, or treatments involving differentiation of chondrocytes and the control of cartilaginous osteogenesis.

    摘要翻译： 本发明涉及来自软骨细胞的不存在于来自软骨细胞的去分化细胞中的纯化和分离的伴刀豆球蛋白A-结合蛋白。 本发明还涉及在SDS-PAGE中分子量约76kD的纯化和分离的软骨细胞膜蛋白（CMP），其是刀豆素A结合蛋白，分子量约为76kD。 用糖苷内切酶处理后，CMP的表观分子量约为67kD。 给出了N末端氨基酸序列和几个内部氨基酸序列。 这些蛋白质可用于测定，方法或涉及软骨细胞分化和控制软骨成骨的治疗。