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    RADIOPAQUE INTRALUMINAL STENTS COMPRISING COBALT-BASED ALLOYS CONTAINING ONE OR MORE PLATINUM GROUP METALS, REFRACTORY METALS, OR COMBINATIONS THEREOF
    5.
    发明申请
    RADIOPAQUE INTRALUMINAL STENTS COMPRISING COBALT-BASED ALLOYS CONTAINING ONE OR MORE PLATINUM GROUP METALS, REFRACTORY METALS, OR COMBINATIONS THEREOF 审中-公开
    包含含有一种或多种铂族金属，碱金属或其组合的基于钴的合金的放射性体系

    公开(公告)号：US20120123525A1

    公开(公告)日：2012-05-17

    申请号：US13298070

    申请日：2011-11-16

    申请人： Pamela A. Kramer-Brown ,  Austin M. Leach ,  Randolf Von Oepen

    发明人： Pamela A. Kramer-Brown ,  Austin M. Leach ,  Randolf Von Oepen

    IPC分类号： A61F2/82

    CPC分类号： A61L31/022 ,  A61L31/18

    摘要： Embodiments are directed to radiopaque implantable structures (e.g., stents) formed of cobalt-based alloys that comprise cobalt, chromium and one or more platinum group metals, refractory metals, or combinations thereof. Platinum group metals include platinum, palladium, ruthenium, rhodium, osmium, and iridium. Here, the term “refractory metals” include zirconium, niobium, rhodium, molybdenum, hafnium, tantalum, tungsten, rhenium, as well as the precious metals silver and gold. In one embodiment, the one or more included platinum group or refractory metals substitute for nickel, such that the alloy is substantially nickel free. The stents exhibit improved radiopacity as compared to similar alloys including greater amounts of nickel.

    摘要翻译： 实施例涉及由包含钴，铬和一种或多种铂族金属，难熔金属或其组合的钴基合金形成的不透射线的可植入结构（例如，支架）。 铂族金属包括铂，钯，钌，铑，锇和铱。 这里，术语“难熔金属”包括锆，铌，铑，钼，铪，钽，钨，铼以及贵金属银和金。 在一个实施方案中，一种或多种包括的铂族或难熔金属代替镍，使得该合金基本上不含镍。 与包括更大量的镍的类似合金相比，支架表现出改善的射线不透性。

    IMPLANTABLE MEDICAL DEVICES INCLUDING A HEAT-TREATED TANTALUM-ALLOY BODY HAVING A DRUG-ELUTING COATING THEREON, AND METHODS OF MAKING AND USING SAME
    6.
    发明申请
    IMPLANTABLE MEDICAL DEVICES INCLUDING A HEAT-TREATED TANTALUM-ALLOY BODY HAVING A DRUG-ELUTING COATING THEREON, AND METHODS OF MAKING AND USING SAME 审中-公开
    包括具有药物涂覆涂层的热处理的钛合金体的可植入医疗装置及其制造方法和使用方法

    公开(公告)号：US20130096666A1

    公开(公告)日：2013-04-18

    申请号：US13271511

    申请日：2011-10-12

    申请人： Rainer Bregulla ,  Randolf Von Oepen ,  Pamela A. Kramer-Brown ,  Austin M. Leach

    发明人： Rainer Bregulla ,  Randolf Von Oepen ,  Pamela A. Kramer-Brown ,  Austin M. Leach

    IPC分类号： A61F2/82 ,  C22F1/18 ,  B05D3/02 ,  B05D7/14

    CPC分类号： A61L31/088 ,  A61L31/022 ,  A61L31/146 ,  A61L31/16 ,  A61L2300/416

    摘要： The present disclosure is directed to a drug-eluting implantable medical devices that includes a tantalum-alloy body having a drug-eluting coating thereon for delivering a drug to treat, for example, restenosis. In an embodiment, an implantable medical device includes a body sized and configured to be implanted in a living subject. At least a portion of the body may comprise a tantalum alloy. The tantalum alloy includes a tantalum content of about 77 weight % (“wt %”) to about 92 wt %, a niobium content of about 7 wt % to about 13 wt %, and a tungsten content of about 1 wt % to about 10 wt %. The tantalum alloy exhibits at least one mechanical property modified by heat treatment thereof. The body has a drug-eluting coating thereon.

    摘要翻译： 本公开涉及药物洗脱可植入医疗装置，其包括其上具有药物洗脱涂层的钽合金体，用于递送药物以治疗例如再狭窄。 在一个实施例中，可植入医疗装置包括尺寸和构造成植入生物体内的体。 身体的至少一部分可以包括钽合金。 钽合金包括约77重量％（“重量％”）至约92重量％的钽含量，约7重量％至约13重量％的铌含量和约1重量％至约10重量％的钨含量 重量％。 钽合金具有通过其热处理而改性的至少一种机械性能。 身体上有药物洗脱涂层。

    HEAT-TREATED TANTALUM-ALLOY PRODUCTS, IMPLANTABLE MEDICAL DEVICES INCORPORATING SAME, AND METHODS OF PROCESSING TANTALUM-ALLOY PRODUCTS
    8.
    发明申请
    HEAT-TREATED TANTALUM-ALLOY PRODUCTS, IMPLANTABLE MEDICAL DEVICES INCORPORATING SAME, AND METHODS OF PROCESSING TANTALUM-ALLOY PRODUCTS 有权
    热处理的钛合金产品，含有其的可植入医疗装置以及处理钛合金产品的方法

    公开(公告)号：US20130096667A1

    公开(公告)日：2013-04-18

    申请号：US13271869

    申请日：2011-10-12

    申请人： Rainer Bregulla ,  Randolf von Oepen ,  Pamela A. Kramer-Brown ,  Austin M. Leach

    发明人： Rainer Bregulla ,  Randolf von Oepen ,  Pamela A. Kramer-Brown ,  Austin M. Leach

    IPC分类号： A61F2/82 ,  C23F1/00 ,  C22F1/18

    CPC分类号： A61L31/022 ,  A61L31/14

    摘要： The present disclosure is directed to tantalum-alloy products, implantable medical devices that incorporate tantalum-alloy products such as stents or other implantable medical devices, methods of making and/or processing the tantalum-alloy products and implantable medical devices, and methods of using the implantable medical devices. In an embodiment, a stent includes a stent body having a plurality of struts. At least a portion of the stent body is made from a tantalum alloy. The tantalum alloy includes a tantalum content of about 77 weight % (“wt %”) to about 92 wt %, a niobium content of about 7 wt % to about 13 wt %, and a tungsten content of about 1 wt % to about 10 wt %. The tantalum alloy exhibits at least one mechanical property modified by heat treatment thereof, such as yield strength, ultimate tensile strength, or ductility.

    摘要翻译： 本公开涉及钽合金产品，结合钽合金产品例如支架或其他可植入医疗装置的可植入医疗装置，制造和/或加工钽合金产品和可植入医疗装置的方法以及使用方法 可植入医疗器械。 在一个实施例中，支架包括具有多个支柱的支架主体。 支架主体的至少一部分由钽合金制成。 钽合金包括约77重量％（“重量％”）至约92重量％的钽含量，约7重量％至约13重量％的铌含量和约1重量％至约10重量％的钨含量 重量％。 钽合金表现出至少一种通过其热处理改性的机械性能，例如屈服强度，极限拉伸强度或延展性。