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公开(公告)号：US08883185B2
公开(公告)日：2014-11-11
申请号：US13115049
申请日：2011-05-24
申请人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Saumya Banerjee , Timothy Sargeant , Joshua Stopek
发明人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Saumya Banerjee , Timothy Sargeant , Joshua Stopek
CPC分类号： A61L27/16 , A61K9/06 , A61K31/00 , A61K47/08 , A61K47/18 , A61K47/32 , A61K47/34 , A61L27/18 , A61L27/52 , A61L27/54 , A61L31/145 , A61L2430/38
摘要： The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号：US08591929B2
公开(公告)日：2013-11-26
申请号：US13115066
申请日：2011-05-24
申请人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
发明人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
CPC分类号： A61K31/00 , A61L31/145 , A61L31/16 , A61L2300/00
摘要： The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号：US20110293699A1
公开(公告)日：2011-12-01
申请号：US13115079
申请日：2011-05-24
申请人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
发明人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
IPC分类号： A61K47/30 , A61K9/00 , A61K9/127 , A61P31/00 , A61P29/00 , A61P1/00 , A61P25/08 , A61P9/00 , A61P21/02 , A61P35/00 , A61P37/06 , A61K47/32 , A61P23/00
CPC分类号： A61K31/00 , A61K9/0024 , A61K9/06 , A61K47/34 , C08J3/075 , C08J3/246 , C08J2371/02 , A61K2300/00
摘要： The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号：US08734824B2
公开(公告)日：2014-05-27
申请号：US13115060
申请日：2011-05-24
申请人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
发明人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
CPC分类号： A61L24/0031 , A61K31/00 , A61L24/046 , A61L26/0014 , A61L31/10 , A61L31/14 , A61L31/145
摘要： The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
摘要翻译： 本公开涉及水凝胶组合物及其使用方法。 水凝胶组合物可包括在接触时彼此反应的前体以及与引发剂接触时反应的前体。 在实施方案中，所得到的水凝胶可具有不同密度和较不致密区域的交联水平。
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公开(公告)号：US20110293669A1
公开(公告)日：2011-12-01
申请号：US13115017
申请日：2011-05-24
申请人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
发明人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
CPC分类号： A61K47/10 , A61K9/06 , A61K31/00 , A61K47/32 , A61K47/34 , A61L24/0031 , A61L24/046 , A61L27/18 , A61L27/52 , A61L31/06 , A61L31/145
摘要： The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号：US08968783B2
公开(公告)日：2015-03-03
申请号：US13115017
申请日：2011-05-24
申请人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
发明人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla
IPC分类号： A61K47/34 , A61K9/00 , A61L27/52 , A61P7/04 , A61P9/00 , A61K47/32 , A61K9/06 , A61K31/00 , A61L24/00 , A61L24/04 , A61L27/18 , A61L31/06 , A61L31/14
CPC分类号： A61K47/10 , A61K9/06 , A61K31/00 , A61K47/32 , A61K47/34 , A61L24/0031 , A61L24/046 , A61L27/18 , A61L27/52 , A61L31/06 , A61L31/145
摘要： The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号：US08591950B2
公开(公告)日：2013-11-26
申请号：US13115079
申请日：2011-05-24
申请人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
发明人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
IPC分类号： A61K47/30 , A61K9/00 , A61K9/127 , A61P31/00 , A61P29/00 , A61P1/00 , A61P25/08 , A61P9/00 , A61P21/02 , A61P35/00 , A61P37/06 , A61K47/32 , A61P23/00
CPC分类号： A61K31/00 , A61K9/0024 , A61K9/06 , A61K47/34 , C08J3/075 , C08J3/246 , C08J2371/02 , A61K2300/00
摘要： The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号：US20120064299A1
公开(公告)日：2012-03-15
申请号：US13222801
申请日：2011-08-31
申请人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
发明人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Timothy Sargeant , Joshua Stopek
摘要： The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
摘要翻译： 本公开涉及水凝胶组合物及其使用方法。 水凝胶组合物可包括在接触时彼此反应的前体以及与引发剂接触时反应的前体。 在实施方案中，所得到的水凝胶可具有不同密度和较不致密区域的交联水平。
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公开(公告)号：US20110293687A1
公开(公告)日：2011-12-01
申请号：US13115049
申请日：2011-05-24
申请人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Saumya Banerjee , Timothy Sargeant , Joshua Stopek
发明人： Steven Bennett , Nathaniel Mast , Kevin Lavigne , Walter Skalla , Saumya Banerjee , Timothy Sargeant , Joshua Stopek
CPC分类号： A61L27/16 , A61K9/06 , A61K31/00 , A61K47/08 , A61K47/18 , A61K47/32 , A61K47/34 , A61L27/18 , A61L27/52 , A61L27/54 , A61L31/145 , A61L2430/38
摘要： The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
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公开(公告)号：US09592108B2
公开(公告)日：2017-03-14
申请号：US12791534
申请日：2010-06-01
申请人： Kevin Lavigne , Steven Bennett , Nathaniel Mast
发明人： Kevin Lavigne , Steven Bennett , Nathaniel Mast
CPC分类号： A61F2/0063 , A61B17/3468 , A61B2017/00287 , A61F2002/0072 , A61L27/34 , A61L27/52 , A61L27/56
摘要： The present disclosure includes systems and a method for in situ application of a surgical patch during minimally invasive surgery. The method includes the steps of inserting a surgical patch into a bag; transferring a polymeric bag containing a hemostatic patch into a body cavity; removing the surgical patch from the polymeric bag while the polymeric bag is within the body cavity; and applying the surgical patch to a tissue within the body cavity.
摘要翻译： 本公开包括在微创手术期间外科手术贴片的原位应用的系统和方法。 该方法包括将外科补片插入袋中的步骤; 将含有止血贴片的聚合物袋转移到体腔中; 当所述聚合物袋在所述体腔内时，从所述聚合物袋中移除所述手术贴片; 以及将所述外科补片应用于所述体腔内的组织。
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