摘要:
The present invention relates to a method for producing transgenic plants, which involves producing hemagglutinin proteins of the H5N1 virus using a plant transformation recombinant vector, wherein said vector can express hemagglutinin proteins of the H5N1 virus, the highly pathogenic avian influenza virus, and transport proteins expressed in plants to the endoplasmic reticulum and enable the retention of the proteins in the endoplasmic reticulum to enable glycosylation required for antigen activity. The present invention also relates to a method for the mass production of hemagglutinin proteins of the antigenic H5N1 virus from transgenic plants or a vaccine composition for the avian influenza virus comprising the transgenic plants or the hemagglutinin proteins produced from the plants. The transgenic plants can be used as edible vaccines, antigenic hemagglutinin proteins produced can be used as protein vaccines for the H5N1 avian influenza virus, or as diagnostic reagents for avian influenza virus infection.
摘要:
The objective of this invention is to provide a process of manufacturing cephem derivatives expressed by the following formula (1), wherein the compound (2) is reacted with an condensing agent of the compound (4) and 1-hydroxy-6-trifluoromethyl benzotriazole(5) and the mixture is acylated with 7-aminocephosporanic acid (3) or its derivatives. ##STR1## According to this invention, a desirous product with high purity may be obtained, which is more cost-saving and industrially feasible than the conventional methods, under the following process steps: Without protecting amino group of organic acid (2), conversion of the reactive derivatives under mild temperature is made and the acylation is directly carried out to obtain the final product.
摘要:
The present invention relates to an intracellular viral vector delivery method employing an iron ion/viral vector composite. The iron ion/viral vector composite according to the present invention is not dependent on the expression of CAR and so improves the efficiency of delivery of viral vectors and gene expression in cells of diverse types, and has an outstanding virus-neutralizing antibody escape performance, exhibits little cytotoxicity and is outstandingly stable even when subjected to iron ion processing at low concentration, and hence can be used to advantage in recombinant viral vaccine compositions.
摘要:
The present invention relates to an alpha lipoic acid capsule composition stabilized in aqueous phase, which can effectively prevent alpha lipoic acid from decomposing due to external environmental conditions, such as water, temperature, light, and the like, and can maintain the stability of alpha lipoic acid from the interaction between the lipoic acid and other materials, which are added together with the lipoic acid when the lipoic acid is applied to cosmetics, foods, or medical supplies, by mixing water-dispersed alpha lipoic acid, a water-insoluble polymer having self-emulsification properties, and a hydrophilic solvent, thus capsulating alpha lipoic acid, and to a method of preparing the same.
摘要:
The present invention relates to an intracellular viral vector delivery method employing an iron ion/viral vector composite. The iron ion/viral vector composite according to the present invention is not dependent on the expression of CAR and so improves the efficiency of delivery of viral vectors and gene expression in cells of diverse types, and has an outstanding virus-neutralizing antibody escape performance, exhibits little cytotoxicity and is outstandingly stable even when subjected to iron ion processing at low concentration, and hence can be used to advantage in recombinant viral vaccine compositions.
摘要:
A theater seat providing a multi-dimensional sense is provided which allows the audience to directly or indirectly sense various special effects to be absorbed in a movie by stimulating the audience's five senses and presenting environmental conditions substantially similar to the movie. The theater seat providing a multi-dimensional sense includes: a seat having a seat section, a backrest, and a headrest; a motion unit allowing the seat to move vertically, horizontally, and anteroposteriorly; a vibration unit applying local vibrations to a user's hips, femoral region, and back and waist; a speaker transmitting sounds to the user; an actuator stimulating the user's back and waist; an ejection device ejecting a predetermined special effect material to the user; and a controller controlling operations of the motion unit, the vibration unit, the speaker, the actuator, and the ejection device.
摘要:
A wall panel structure for controlling humidity within a building having a panel assembly attachable to an inner wall surface of the building including: a first panel having a surface with a first predetermined porosity to moisture; and a second panel secured to said first panel with a space for accomodating airflow between the first and second panels, the second panel having a surface with a second predetermined porosity to moisture, the first perdetermined panel porosity being greater than the second predetermined porosity to thereby absorb moisture from air being circulated between the first and second panels; whereby humidity of an environment within the building is controllable. The first and second panels are fabricated from compressed wood particles, a first compression density of the first panel being selected to achieve the first predetermined porosity and a second compression density of the second panel being selected to achieve the second predetermined porosity, the first compression density being less than the second compression density. Airflow channels are formed in a criss-cross pattern in the second panel to facilitate air circulation between the panels.